Re-analyzing the trial that found ECT=ketamine in TRD, we learn: 1. ECT better for severe or hospitalized cases https://t.co/F3wQyQFhpV 2. Patient preference skewed the results in favor of ketamine: https://t.co/Fmt1KAdSGO Also, psychosis excluded, and responds better to ECT. https://t.co/BDbnk9qSEh
Ketamine vs Electroconvulsive Therapy for Treatment-Resistant Depression: A Secondary Analysis of a Randomized Clinical Trial.
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Jun 2024 – Mar 2025Where it's discussed
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X / Twitter19 posts
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News11 articles
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Blogs4 articles
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Facebook3 posts
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YouTube2 videos
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Bluesky1 posts
AI synopsis
What people are saying
The collective discussions show a focus on the comparative effectiveness of ketamine and ECT, with posts citing specific data like depression score improvements and patient suitability, using tone and terminology that indicate both support and curiosity about clinical implications and nuanced results.
Most discussions recognize that ketamine shows comparable or better outcomes than ECT, with some emphasizing its effectiveness, indicating general support for the study's findings.
Posts demonstrate moderate curiosity, referencing specific results like improvements in depression scores and highlighting particular patient groups, which suggests a decent level of engagement.
Several users reference detailed aspects such as patient preferences, clinical features, and statistical outcomes, showing a thoughtful and analytical approach.
The discussions highlight the potential for changing treatment approaches, especially favoring ketamine in certain cases, reflecting a recognition of meaningful implications.
Abstract in brief
- The ELEKT-D trial explored whether intravenous ketamine is as effective as ECT for patients with treatment-resistant depression (TRD), finding that ketamine is noninferior to ECT in this group.
- This secondary analysis aimed to identify which clinical features might predict better outcomes with either ketamine or ECT in treating TRD.
- The study involved 365 participants from five U.S. medical centers, comparing treatment responses based on various baseline factors, such as depression severity and cognitive function, using advanced statistical methods.
Top posts
Most liked on X and BlueskyKetamine vs Electroconvulsive Therapy for Treatment-Resistant Depression: A Secondary Analysis of a Randomized Clinical Trial - PubMed https://t.co/iPnBmnmrFS
Re-analyzing the trial that found ECT=ketamine in TRD, we learn: 1. ECT better for severe or hospitalized cases pubmed.ncbi.nlm.nih.gov/38916891 2. Patient preference skewed the results in favor of ketamine: pubmed.ncbi.nlm.nih.gov/40049091 Also, psychosis excluded, and responds better to ECT.
Bei moderater bis schwerer Depression besser Ketamin als EKT: Dallas – Im Fachblatt JAMA Network Open (2024; DOI: 10.1001/jamanetworkopen.2024.17786) berichten US-Forschende, an welchen Merkmalen man Patienten mit… https://t.co/vmPFVKrx8U #JAMANetworkOpen #NEJM https://t.co/Af8lFoyjqN
Study: Ketamine more effective than ECT for depression treatment. Well done @BrianBarnettMD ! https://t.co/3KPTnnViwL @JAMA_current
Greater improvement in depression was observed w/ IV ketamine among outpatients with nonpsychotic Treatment Resistant Depression (TRD) who had moderately severe or severe depression, suggesting these patients may consider ketamine over ECT for TRD. https://t.co/h2u5dQnhGh
All mentions
Exploring Ketamine Clinics: A Transformative Journey for Physicians
This episode of the Ketamine Startup Podcast shares insights on opening a ketamine clinic, discussing the efficacy of IV ketamine for mental health issues. Learn about treatment resistance, especially in depression, and…
Ketamine Clinics: Addressing Mental Health with Innovative Therapy
This episode covers the journey of opening a ketamine clinic with insights from a presentation by Sam at the ACEP Scientific Assembly. Learn about the efficacy of IV ketamine for treatment-resistant depression, anxiety…
RT @chrisaikenmd: Re-analyzing the trial that found ECT=ketamine in TRD, we learn: 1. ECT better for severe or hospitalized cases https://…
RT @chrisaikenmd: Re-analyzing the trial that found ECT=ketamine in TRD, we learn: 1. ECT better for severe or hospitalized cases https://…
RT @chrisaikenmd: Re-analyzing the trial that found ECT=ketamine in TRD, we learn: 1. ECT better for severe or hospitalized cases https://…
RT @chrisaikenmd: Re-analyzing the trial that found ECT=ketamine in TRD, we learn: 1. ECT better for severe or hospitalized cases https://…
Re-analyzing the trial that found ECT=ketamine in TRD, we learn: 1. ECT better for severe or hospitalized cases pubmed.ncbi.nlm.nih.gov/38916891 2. Patient preference skewed the results in favor of ketamine: pubmed.ncbi.nlm.nih.gov/40049091 Also, psychosis excluded, and responds better to ECT.
RT @chrisaikenmd: Re-analyzing the trial that found ECT=ketamine in TRD, we learn: 1. ECT better for severe or hospitalized cases https://…
RT @chrisaikenmd: Re-analyzing the trial that found ECT=ketamine in TRD, we learn: 1. ECT better for severe or hospitalized cases https://…
RT @chrisaikenmd: Re-analyzing the trial that found ECT=ketamine in TRD, we learn: 1. ECT better for severe or hospitalized cases https://…
RT @chrisaikenmd: Re-analyzing the trial that found ECT=ketamine in TRD, we learn: 1. ECT better for severe or hospitalized cases https://…
RT @chrisaikenmd: Re-analyzing the trial that found ECT=ketamine in TRD, we learn: 1. ECT better for severe or hospitalized cases https://…
Re-analyzing the trial that found ECT=ketamine in TRD, we learn: 1. ECT better for severe or hospitalized cases https://t.co/F3wQyQFhpV 2. Patient preference skewed the results in favor of ketamine: https://t.co/Fmt1KAdSGO Also, psychosis excluded, and responds better to ECT. https://t.co/BDbnk9qSEh
https://t.co/wzJ35QLhSN An amazing article showing efficacy of IV Ket vs ECT.
@the_sigh_op2 Here’s one that contradicts that: https://t.co/a1lK7vyUkk
Bei moderater bis schwerer Depression besser Ketamin als EKT: Dallas – Im Fachblatt JAMA Network Open (2024; DOI: 10.1001/jamanetworkopen.2024.17786) berichten US-Forschende, an welchen Merkmalen man Patienten mit… https://t.co/vmPFVKrx8U #JAMANetworkOpen #NEJM https://t.co/Af8lFoyjqN
Ketamine vs Electroconvulsive Therapy for Treatment-Resistant Depression https://t.co/DESq7JiS3F
RT @AndreyOstrovsky: Study: Ketamine more effective than ECT for depression treatment. Well done @BrianBarnettMD ! https://t.co/3KPTnnViwL…
Ketamine vs Electroconvulsive Therapy for Treatment-Resistant Depression: A Secondary Analysis of a Randomized Clinical Trial - PubMed https://t.co/iPnBmnmrFS
Study: Ketamine more effective than ECT for depression treatment. Well done @BrianBarnettMD ! https://t.co/3KPTnnViwL @JAMA_current
Post Hoc Analysis: > improvement (QIDS-SR16) was observed with IV ketamine vs. ECT among outpatients (−8.4 vs −6.2 points) with moderately severe or severe (−7.7 vs −5.6 points) nonpsychotic TRD https://t.co/eYhx6EKZT9 https://t.co/r3XVetGN6M
Greater improvement in depression was observed w/ IV ketamine among outpatients with nonpsychotic Treatment Resistant Depression (TRD) who had moderately severe or severe depression, suggesting these patients may consider ketamine over ECT for TRD. https://t.co/h2u5dQnhGh