November 2023 PMID 38938724

Effects of Vitamin K2 and D Supplementation on Coronary Artery Disease in Men: A RCT.

Selma Hasific, Kristian A Oevrehus, Jes S Lindholt, Anna Mejldal, Damini Dey, Jordi S Dahl, Niels Erik Frandsen, Søren Auscher, Jess Lambrechtsen, Susanne Hosbond, Dilek Alan, Grazina Urbonaviciene, Søren Becker, Lars M Rasmussen, Axel P Diederichsen

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Mentions

55
Peak: 7 in Nov 2023
across 6 sources since Nov 2023

Extended reach

3,709,789
potential audience

Total likes

118,498

Video views

3,315,758

Mentions per month

Nov 2023 – Dec 2025

Where it's discussed

  • X / Twitter34 posts
  • YouTube11 videos
  • News4 articles
  • Facebook2 posts
  • Reddit2 posts
  • Blogs2 articles

AI synopsis

What people are saying

The discussions reveal a generally positive view toward the study, with examples like users mentioning benefits for those with scores above 400 and discussing how vitamins K2 and D activate calcium-related proteins. The tone mixes scientific referencing and personal recommendations, reflecting moderate engagement and interest, but overall, the impact is cautious due to mixed study results.

AgreementModerate agreement

Most discussions acknowledge the study's neutral overall findings but highlight potential benefits for specific groups, such as those with higher calcium scores.

InterestHigh interest

Posts show high interest, referencing multiple sources, mentioning potential impacts, and discussing vitamin K2 and D's relevance in popular health topics.

EngagementModerate engagement

Several comments go beyond simple sharing, referencing physiological mechanisms, asking questions, or suggesting personal actions, indicating moderate but meaningful engagement.

ImpactModerate impact

While the study's neutral main result is recognized, many users focus on the potential benefits for individuals with high calcium scores, suggesting some influence on health perspectives.

Abstract in brief

  • The study examined whether vitamin K2 and D supplementation could slow down the progression of coronary artery calcification (CAC), which is linked to heart attacks and mortality.
  • A total of 389 participants were included in this double-blinded trial, but results showed no significant difference in overall CAC progression between the supplementation and placebo groups over two years.
  • However, those with higher CAC scores (≥400 AU) experienced less progression with the supplements, and safety events were lower in the supplementation group, suggesting potential benefits worth exploring in future research.

Top posts

Most liked on X and Bluesky
Dr Dave Cartland BMedSc MBChB Ex-MRCGP
@CartlandDavid · X

Effects of Vitamin K2 and D Supplementation on Coronary Artery Disease in Men: A RCT - ScienceDirect https://t.co/mZTC5pQ4Br

Jan 10, 2025 · 20 likes · 3 shares · 304,767 followers View post →
Mike Lustgarten, PhD
@mike_lustgarten · X

Effects of Vitamin K2 and D Supplementation on Coronary Artery Disease in Men: A RCT https://t.co/4XMH6JHZiN

Oct 26, 2024 · 14 likes · 9,717 followers View post →
Roger Blumenthal
@rblument1 · X

Effects of Vitamin K2 and D Supplementation on Coronary Artery Disease in Men: A RCT | JACC: Advances https://t.co/oL5jeqAs9z

Nov 14, 2023 · 5 likes · 3 shares · 8,806 followers View post →
André Wambier
@AndreWambier · X

Os MELHORES alimentos para LIMPAR Suas Artérias! Suplementos e vitamina... https://t.co/NB1AHMThqp via @YouTube

Apr 5, 2024 · 2 likes · 1 share · 179 followers View post →
Selma Hasific
@SelmaHasific · X

@NdidiWrites @damini_dey @KajetanGrodecki @DCAcademyDK @CardResearchOuh Hi! Thank you for your interest. Learn about the results of our study here https://t.co/o96RlwoI56. The primary results were neutral, however, we found a significant effect of vitamin K2 and D3 in patients with CAC score > 400.

Jul 18, 2024 · 2 likes · 92 followers View post →
Jaimie Drew
@JDrewsyBC · X

Anyone taking Vitamin K2 - worth a watch! https://t.co/VcIL0vgXOm

Mar 3, 2024 · 1 like · 7,346 followers View post →

All mentions

Greta Compton Dip DH RCSEd aka Gretsky
@Gretsky_Compton · X

Effects of Vitamin K2 and D Supplementation on Coronary Artery Disease in Men: A RCT | JACC: Advances https://t.co/fgLTy1p1wD

Mar 20, 2025 · 1 like · 903 followers View post →
SheelaghG.
@SheelaghG · X

RT @CartlandDavid: Effects of Vitamin K2 and D Supplementation on Coronary Artery Disease in Men: A RCT - ScienceDirect https://t.co/mZTC5p…

Jan 10, 2025 · 3 shares · 4,695 followers View post →
Dr Jennine Morgan
@jemmm85517813 · X

RT @CartlandDavid: Effects of Vitamin K2 and D Supplementation on Coronary Artery Disease in Men: A RCT - ScienceDirect https://t.co/mZTC5p…

Jan 10, 2025 · 3 shares · 16,590 followers View post →
We R Living on Planet Stupid
@101Planet100 · X

RT @CartlandDavid: Effects of Vitamin K2 and D Supplementation on Coronary Artery Disease in Men: A RCT - ScienceDirect https://t.co/mZTC5p…

Jan 10, 2025 · 3 shares · 425 followers View post →
Dr Dave Cartland BMedSc MBChB Ex-MRCGP
@CartlandDavid · X

Effects of Vitamin K2 and D Supplementation on Coronary Artery Disease in Men: A RCT - ScienceDirect https://t.co/mZTC5pQ4Br

Jan 10, 2025 · 20 likes · 3 shares · 304,767 followers View post →
#HelpYouGetGAINS
@helpYOUgetGAINS · X

RT @MichaelHen26343: Why Vitamin K2 & D3 Are Exploding in Popularity https://t.co/k2ZhdZP9XQ via @YouTube https://t.co/imvS1gC1h9

Jan 4, 2025 · 1 share · 16,831 followers View post →
Michael Henry
@MichaelHen26343 · X

Why Vitamin K2 & D3 Are Exploding in Popularity https://t.co/k2ZhdZP9XQ via @YouTube https://t.co/imvS1gC1h9

Jan 4, 2025 · 1 like · 1 share · 82 followers View post →
Scott Campbell
@ScottCa85749680 · X

Why Vitamin K2 & D3 Are Exploding in Popularity https://t.co/Qp8doZ9Bgv via @YouTube

Dec 25, 2024 · 1 followers View post →
Herbert_J_Mann
@Herbert_J_Mann · X

New Information on whether you should take Vitamin K2-MK-7 and Vitamin D3 Together? - YouTube https://t.co/GDHsyA7EUG

Nov 23, 2024 · 8,960 followers View post →
William Lagakos
@caloriesproper2 · X

@AdvancedForged @BowTiedOx Dunno about that, brief search suggests benefit https://t.co/Qt1NFTF5Of or no effect https://t.co/eka6sO8OKC & https://t.co/kYgwH8nHwo

Nov 15, 2024 · 2,693 followers View post →
Mike Lustgarten, PhD
@mike_lustgarten · X

Effects of Vitamin K2 and D Supplementation on Coronary Artery Disease in Men: A RCT https://t.co/4XMH6JHZiN

Oct 26, 2024 · 14 likes · 9,717 followers View post →
Carlos Eduardo Campos Simões
@dreduardoADVOGA · X

10 INCRÍVEIS ALIMENTOS que TRANSFORMAM sua CIRCULAÇÃO | LIMPAM até 95,6%... https://t.co/ZXxpbI0TIG via @YouTube

Oct 8, 2024 · 103 followers View post →
Dr.Glover31
@Glover31Dr · X

Effects of Vitamin K2 and D Supplementation on Coronary Artery Disease in Men: A RCT | JACC: Advances https://t.co/dm2i6N86UJ

Sep 11, 2024 · 36 followers View post →
terezinha mendonça bitencourt
@terezinhamend18 · X

10 INCRÍVEIS ALIMENTOS que TRANSFORMAM sua CIRCULAÇÃO | LIMPAM até 95,6%... https://t.co/7OLrPSlVes via @YouTube

Aug 1, 2024 · 1 like · 201 followers View post →
Selma Hasific
@SelmaHasific · X

@NdidiWrites @damini_dey @KajetanGrodecki @DCAcademyDK @CardResearchOuh Hi! Thank you for your interest. Learn about the results of our study here https://t.co/o96RlwoI56. The primary results were neutral, however, we found a significant effect of vitamin K2 and D3 in patients with CAC score > 400.

Jul 18, 2024 · 2 likes · 92 followers View post →
Peter Andrews
@PeterVermont · X

@pharmacymike21 Not a doctor but I would suggest adding Vitamin K2 if you don’t already take. Evidence is not terrific but it activates calcium related proteins (MGP, calcinin) which put calcium into bones rather than vascular system. https://t.co/Pn193nkoIA

Jul 3, 2024 · 310 followers View post →
Antônio Epaminondas
@AntnioEpam66655 · X

https://t.co/xiac7MqXTT

May 15, 2024 · 3 followers View post →
ela Cris
@crisdia45175536 · X

RT @AndreWambier: Os MELHORES alimentos para LIMPAR Suas Artérias! Suplementos e vitamina... https://t.co/NB1AHMThqp via @YouTube

May 12, 2024 · 1 share · 14 followers View post →
Tania Almeida
@TaniaAl65853424 · X

https://t.co/Avfi0Xlc8a

Apr 20, 2024 · 5 followers View post →
Marcel Güter
@Marcel_Guter · X

10 INCRÍVEIS ALIMENTOS que TRANSFORMAM sua CIRCULAÇÃO | LIMPAM até 95,6%... https://t.co/UpQxZh36UE via @YouTube

Apr 17, 2024 · 536 followers View post →
Matt
@mattdsegal · X

@MatthewJDalby I think my website is being shit again here's the original video https://t.co/lEBSbZ85AY

Apr 11, 2024 · 801 followers View post →
André Wambier
@AndreWambier · X

Os MELHORES alimentos para LIMPAR Suas Artérias! Suplementos e vitamina... https://t.co/NB1AHMThqp via @YouTube

Apr 5, 2024 · 2 likes · 1 share · 179 followers View post →
Steven Mathern
@StevenMathern · X

@RolandBakerIII , what do u think? i think it might reduced the cvd dr Bagai is showing here . https://t.co/E9msiEmdSE

Mar 11, 2024 · 1 like · 457 followers View post →
Jaimie Drew
@JDrewsyBC · X

Anyone taking Vitamin K2 - worth a watch! https://t.co/VcIL0vgXOm

Mar 3, 2024 · 1 like · 7,346 followers View post →
Chuan
@amitaba33 · X

https://t.co/JwZOM3oNCs

Feb 21, 2024 · 23 followers View post →
dr Julia Murlewska
@juliaewamurl · X

Various studies have been conducted to determine the impact of Vitamin K2 supplementation on calcium buildup in bones, heart valves, and blood vessels. https://t.co/owFX9K0pjH

Feb 18, 2024 · 827 followers View post →
Bartosz Białas
@BartoszBialas · X

https://t.co/Vhq6RwtsDZ

Feb 18, 2024 · 10 followers View post →
David Winchester @drdavemd.bsky.social
@drdavemd · X

Taking vitamins K and D for 2 years does not prevent progression of coronary calcium https://t.co/87X0vZXv1z @JACCJournals

Nov 28, 2023 · 1 like · 1,004 followers View post →
Coronary 4Front
@Coronary4front · X

Effects of Vitamin K2 & D Supplementation on CAD in Men: A RCT @JACCJournals⁩ .Thoughts? ⁦@webmd11⁩ ⁦@DavidLBrownMD⁩ ⁦@DrMarthaGulati⁩ ⁦@mirvatalasnag⁩ ⁦@pash22⁩ ⁦@drjohnm⁩ ⁦@gbiondizoccai⁩ ⁦@sbrugaletta⁩ https://t.co/om8FdhjWvD

Nov 25, 2023 · 1,766 followers View post →
Dr M. Mahesh (ಮಹೇಶ್) (he/him/his)
@mmahesh1 · X

Nice comparative study - People w Calcium scores greater than 400 benefitted & stabilized progression from vitamin K2 and D intake. https://t.co/hWcS2d5sqJ https://t.co/760QzkAxIU

Nov 16, 2023 · 1 like · 5,273 followers View post →
JG FNP-BC
@soonergise · X

RT @rblument1: Effects of Vitamin K2 and D Supplementation on Coronary Artery Disease in Men: A RCT | JACC: Advances https://t.co/oL5jeqAs9z

Nov 14, 2023 · 3 shares · 250 followers View post →
craig dolan
@craig_dolan · X

RT @rblument1: Effects of Vitamin K2 and D Supplementation on Coronary Artery Disease in Men: A RCT | JACC: Advances https://t.co/oL5jeqAs9z

Nov 14, 2023 · 3 shares · 150 followers View post →
Jeff A ⚜️
@JeffA000 · X

RT @rblument1: Effects of Vitamin K2 and D Supplementation on Coronary Artery Disease in Men: A RCT | JACC: Advances https://t.co/oL5jeqAs9z

Nov 14, 2023 · 3 shares · 123 followers View post →
Roger Blumenthal
@rblument1 · X

Effects of Vitamin K2 and D Supplementation on Coronary Artery Disease in Men: A RCT | JACC: Advances https://t.co/oL5jeqAs9z

Nov 14, 2023 · 5 likes · 3 shares · 8,806 followers View post →