Medication-Induced Weight Change Across Common Antidepressant Treatments: A Target Trial Emulation Study: Annals of Internal Medicine @jasonpblock and colleagues https://t.co/BVXgaPnGxB
Medication-Induced Weight Change Across Common Antidepressant Treatments : A Target Trial Emulation Study.
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Jul 2024 – Oct 2025Where it's discussed
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What people are saying
In the discussions, users frequently mention the implications of the study in practical terms, such as 'Will I gain weight?!' reflecting their concern before starting antidepressants. Several posts highlight bupropion as a 'correct answer' for those worried about weight gain, emphasizing its potential benefits. The choice of words like 'important question' and phrases that suggest a transformational insight indicate a strong engagement with the topic, contributing to the overall high sentiment around the article.
The majority of discussions reflect a strong consensus on the findings of the study regarding weight changes associated with different antidepressants, particularly highlighting the benefits of bupropion.
Participants show high curiosity, as evidenced by multiple posts referencing study findings and elaborating on different medications and their impacts on weight.
Many discussions dive into details about particular antidepressants and their effects, showing a deeper level of investigation and personal connection to the topic.
The discussions indicate that there is a strong belief in the significance of the study's findings in informing treatment options and addressing patient concerns about weight gain.
Abstract in brief
- This study compares weight changes among patients prescribed different first-line antidepressants over a 24-month period using electronic health records from 2010 to 2019 across multiple U.S. health systems.
- Researchers found that several antidepressants, such as escitalopram, paroxetine, and duloxetine, led to greater weight gain compared to sertraline, while bupropion was associated with weight loss.
- The analysis highlighted that escitalopram, paroxetine, and duloxetine increased the likelihood of gaining at least 5% of baseline weight, whereas bupropion significantly reduced that risk.
Top posts
Most liked on X and BlueskyFrom the Annals ‘Spotlight on 2024’ collection: A target trial emulation study found #bupropion was consistently associated with the least weight gain among 8 first-line #antidepressant treatments. https://t.co/fcdmuJ0UJf https://t.co/ICa9ZYaB0w
Correct answer is: Bupropion (Ref: https://t.co/zToWIkQsAa) (Note: Please follow your psychiatrist's advice regarding the choice, dose and duration of antidepressants)
All mentions
Impact of Antidepressants on Weight Change: A Comparative Study
This study compares weight changes among patients prescribed different first-line antidepressants over a 24-month period. Key findings reveal that certain medications led to significant weight gain, while others, like…
Impact of Antidepressants on Weight Change: Key Findings
This video discusses a study from Harvard University examining how certain antidepressants can lead to weight gain. It highlights key findings, including that escitalopram and paroxetine resulted in greater weight gain…
@naoparfait The study for anyone interested in the numbers: https://t.co/K9M8e46upO
RT @AnnalsofIM: From the Annals ‘Spotlight on 2024’ collection: A target trial emulation study found #bupropion was consistently associated…
RT @AnnalsofIM: From the Annals ‘Spotlight on 2024’ collection: A target trial emulation study found #bupropion was consistently associated…
RT @AnnalsofIM: From the Annals ‘Spotlight on 2024’ collection: A target trial emulation study found #bupropion was consistently associated…
From the Annals ‘Spotlight on 2024’ collection: A target trial emulation study found #bupropion was consistently associated with the least weight gain among 8 first-line #antidepressant treatments. https://t.co/fcdmuJ0UJf https://t.co/ICa9ZYaB0w
抗うつ薬と体重変化https://t.co/iGanenV5NR
retro cohort study: Estimated 6-month weight gain was higher for escitalopram (MD=0.41 kg), paroxetine (0.37 kg), duloxetine (0.34 kg), venlafaxine (0.17 kg), and citalopram (0.12 kg) vs. sertraline https://t.co/A9cLgzJojM
RT @AnnalsofIM: Trending on https://t.co/HQyUgwV2bm: Medication-Induced Weight Change Across Common Antidepressant Treatments: A Target Tri…
RT @AnnalsofIM: Trending on https://t.co/HQyUgwV2bm: Medication-Induced Weight Change Across Common Antidepressant Treatments: A Target Tri…
RT @AnnalsofIM: Trending on https://t.co/HQyUgwV2bm: Medication-Induced Weight Change Across Common Antidepressant Treatments: A Target Tri…
Trending on https://t.co/HQyUgwV2bm: Medication-Induced Weight Change Across Common Antidepressant Treatments: A Target Trial Emulation Study: https://t.co/6GmD867J71 https://t.co/KLIgiwywX4
Medication-Induced Weight Change Across Common Antidepressant Treatments: A Target Trial Emulation Study https://t.co/ovxjnu1fjN
Medication-Induced Weight Change Across Common Antidepressant Treatments: A Target Trial Emulation Study https://t.co/WIZU7Pz9DB
Medication-Induced Weight Change Across Common Antidepressant Treatments: A Target Trial Emulation Study https://t.co/naQB7jurE7
Medication-Induced Weight Change Across Common Antidepressant Treatments: A Target Trial Emulation Study https://t.co/p94l4pWcyq
المصدر https://t.co/z3QlZ5a5tu
Cambios de peso inducidos por medicación a lo largo de los tratamientos con antidepresivos comunes: estudio por ensayo de emulación del objetivo https://t.co/Uj8qxIwDs1 PMID 38950403
Which #Antidepressants Cause the Most #WeightGain? A new study revealed that #escitalopram, #paroxetine, and #duloxetine were associated with higher risk of gaining weight, whereas #bupropion showed the least. #AnnalsofInternalMedicine https://t.co/K6rUtn5QgM
RT @EARL_med_tw:
RT @EARL_med_tw:
RT @hyderabaddoctor: Correct answer is: Bupropion (Ref: https://t.co/zToWIkQsAa) (Note: Please follow your psychiatrist's advice regardin…
RT @davearterburn: Medication-Induced Weight Change Across Common Antidepressant Treatments: A Target Trial Emulation Study: Annals of Inte…
Medication-Induced Weight Change Across Common Antidepressant Treatments: A Target Trial Emulation Study: Annals of Internal Medicine: Vol 0, No 0 https://t.co/g7y8BM23XK
Medication-Induced Weight Change Across Common Antidepressant Treatments: A Target Trial Emulation Study: Annals of Internal Medicine: Vol 0, No 0 https://t.co/CT2U2RvOrf
RT @mickael_sp:
RT @mickael_sp:
Medication-Induced Weight Change Across Common Antidepressant Treatments: A Target Trial Emulation Study. https://t.co/KBjfzX4gev
RT @pinacol: 【RCT模倣研究】セルトラリンと比較して、エスシタロプラム、パロキセチン、デュロキセチン、ベンラファキシンおよびシタロプラムはより大きな体重増加が見込まれた。フルオキセチンは同様の体重増加をブプロピオンはより小さな体重増加が見込まれた。 #ペ読 htt…
【RCT模倣研究】セルトラリンと比較して、エスシタロプラム、パロキセチン、デュロキセチン、ベンラファキシンおよびシタロプラムはより大きな体重増加が見込まれた。フルオキセチンは同様の体重増加をブプロピオンはより小さな体重増加が見込まれた。 #ペ読 https://t.co/HFdx5pjqGE
Correct answer is: Bupropion (Ref: https://t.co/zToWIkQsAa) (Note: Please follow your psychiatrist's advice regarding the choice, dose and duration of antidepressants)
Cambio de peso inducido por medicamentos en tratamientos antidepresivos comunes: Se encontraron pequeñas diferencias en el cambio de peso medio entre 8 antidepresivos de primera línea, y el bupropión mostró consistentemente el menor aumento de peso,... https://t.co/NZVCBPsXAl
https://t.co/x7jt3LEYpf
RT @ichiipsy: ブプロピオンは日本では一般的でないけれど、体重増加については害が少ないそうだ。 Medication-Induced Weight Change Across Common Antidepressant Treatments: A Target T…
RT @ichiipsy: ブプロピオンは日本では一般的でないけれど、体重増加については害が少ないそうだ。 Medication-Induced Weight Change Across Common Antidepressant Treatments: A Target T…
ブプロピオンは日本では一般的でないけれど、体重増加については害が少ないそうだ。 Medication-Induced Weight Change Across Common Antidepressant Treatments: A Target Trial Emulation Study: Annals of Internal Medicine: Vol 0, No 0 https://t.co/FcRphIN2pX
https://t.co/x7jt3LEYpf
https://t.co/HeaPNdCuJh Will I gain weight?! This is a very important question for a lot of patients prior to initiation of anti-depressant medication
Researchers compared weight change across 8 common antidepressants for patients starting treatment. Study shows differences in weight, with bupropion consistently causing the least weight gain. Findings provide strong evidence on expected weight changes … https://t.co/pkxV8sGjdZ
RT @davearterburn: Medication-Induced Weight Change Across Common Antidepressant Treatments: A Target Trial Emulation Study: Annals of Inte…
In a new study, antidepressants users had an adjusted rate ratio of 1.21 for >5% weight gain. Risk was elevated for at least 6 years follow-up. Escitalopram, paroxetine, and duloxetine users were 10%-15% more likely to gain weight compared to sertraline. https://t.co/MbX64Z5SBC https://t.co/Hv53o4nPCB
RT @davearterburn: Medication-Induced Weight Change Across Common Antidepressant Treatments: A Target Trial Emulation Study: Annals of Inte…
RT @enango: 米国の8つの医療システムにおける2010~2019年までの電子カルテデータを用いた標的試験模倣(target trial emulation)では,うつ病の第一選択薬による推定6ヵ月体重増加は,服薬アドヒアランスは低かったものの,ブプロピオンが一貫して最…
米国の8つの医療システムにおける2010~2019年までの電子カルテデータを用いた標的試験模倣(target trial emulation)では,うつ病の第一選択薬による推定6ヵ月体重増加は,服薬アドヒアランスは低かったものの,ブプロピオンが一貫して最も体重増加が少なかった. https://t.co/NUnDvncAFi
RT @Pi_iDebbyLin: Our recent work investigated weight gain associated common antidepressants use. Check out the article here: https://t.co/…
RT @davearterburn: Medication-Induced Weight Change Across Common Antidepressant Treatments: A Target Trial Emulation Study: Annals of Inte…
RT @davearterburn: Medication-Induced Weight Change Across Common Antidepressant Treatments: A Target Trial Emulation Study: Annals of Inte…
RT @3stars67664378:
A target trial emulation study found bupropion was consistently associated with the least weight gain among 8 first-line antidepressant treatments. These findings could help guide treatment decisions for patients concerned about weight: https://t.co/6GmD867J71 https://t.co/DFYssNdR5F
Our recent work investigated weight gain associated common antidepressants use. Check out the article here: https://t.co/HT7YPVSYdf
Medication-Induced Weight Change Across Common Antidepressant Treatments: A Target Trial Emulation Study: Annals of Internal Medicine @jasonpblock and colleagues https://t.co/BVXgaPnGxB
Online now in @AnnalsofIM: a new study led by @DeptPopMed's Joshua Petimar adds rigorous evidence on expected weight gain across common first-line antidepressant treatments. Read what Dr. Petimar and team found: https://t.co/NLAnkPm9NU https://t.co/Mr1laQPvfM
Los principales antidepresivos inducen pocos cambios de peso, bupropion muestra la menor ganancia de peso, adhesión a medicamentos es baja, por lo que debe considerarse el aumento de peso cuando se inicien los antidepresivos #antidepressant #weight https://t.co/6xyyX1jqlx
RT @3stars67664378:
RT @3stars67664378: