Researchers from Washington University School of Medicine in St. Louis find that Alzheimer's disease is rare in people with multiple sclerosis with a "rate of amyloid-β plasma biomarker positivity...approximately half the rate in 300 non-MS controls." https://t.co/FjpSKDShhS
Unexpected Low Rate of Amyloid-β Pathology in Multiple Sclerosis Patients.
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Jul 2024 – Jul 2025Where it's discussed
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X / Twitter77 posts
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AI synopsis
What people are saying
Multiple contributors discussed how the study highlights that people with MS have a significantly lower risk of developing Alzheimer's disease, evidenced by phrases like 'far less likely' and detailed statistics about amyloid-β positivity rates. The tone of excitement is reflected in comments such as 'this is interesting on pathophysiological pathway implications', showing that participants view this finding as crucial for future research and treatment strategies.
Discussions show strong consensus and positive reactions to the study's findings.
Contributors express a high level of curiosity and relevance regarding the findings.
Many posts delve deeply into implications, methods, and the significance of the results.
The publication is perceived as having considerable importance for future research and clinical practice.
Abstract in brief
- * A study involving 100 MS patients found that the rate of amyloid-β biomarker positivity was about half compared to 300 non-MS controls, indicating a lower risk of Alzheimer’s in MS patients.
- * Most MS patients with amyloid-β pathology exhibited atypical symptoms for MS, suggesting that the relationship between MS and Alzheimer’s disease could lead to new research opportunities.
Top posts
Most liked on X and BlueskyPeople with MS are far less likely to have Alzheimer's disease, a US study in Annals of Neurology says. The authors - led by @MatthewBrier - found MS patients had far fewer amyloid plaques, a hallmark of Alzheimer's, vs adults without MS. @WUDeptMedicine https://t.co/2bVsEKYeeS
Unexpected Low Rate of Amyloid‐β Pathology in Multiple Sclerosis Patients https://t.co/J2z9HNSJVr
A very provocative study led by @MatthewBrier and @AnneHCross1: Unexpected Low Rate of Amyloid‐β Pathology in Multiple Sclerosis Patients - Brier - Annals of Neurology - Wiley Online Library https://t.co/cVUDNROwws
Does Multiple Sclerosis prevent Alzheimer's Disease? https://t.co/khXl3RjZW4 https://t.co/0PCkLCK8hA
Unexpected Low Rate of Amyloid‐β Pathology in Multiple Sclerosis Patients - Brier - Annals of Neurology - Wiley Online Library https://t.co/GD7nsWtC1h
All mentions
Impact of Multiple Sclerosis on Alzheimer's Disease Risk
A recent study indicates that individuals with multiple sclerosis (MS) have a significantly lower risk of developing Alzheimer's disease. Researchers found that MS patients showed about half the rate of amyloid-β…
Exploring Multiple Sclerosis' Protective Effects Against Alzheimer's
Would it surprise you to find out that MS is actually good for something? A recent study shows that MS patients experience a significantly lower rate of Alzheimer’s, with only half showing amyloid-β positivity compared…
Hello @brandon-beaber.bsky.social, reading this news
RT @thmonk_pf: MS患者群では非MS対照群と比較してAlzheimer病理が有意に少ない APS2陽性率(7.1% vs 15.3%)、p-tau217比陽性率(9% vs 18.3%)が有意に低値 現時点ではメカニズムは不明、ただしMS症例の90%はDMTを…
RT @thmonk_pf: MS患者群では非MS対照群と比較してAlzheimer病理が有意に少ない APS2陽性率(7.1% vs 15.3%)、p-tau217比陽性率(9% vs 18.3%)が有意に低値 現時点ではメカニズムは不明、ただしMS症例の90%はDMTを…
RT @Brandon_Beaber: Does Multiple Sclerosis prevent Alzheimer's Disease? https://t.co/khXl3RjZW4 https://t.co/0PCkLCK8hA
RT @Brandon_Beaber: Does Multiple Sclerosis prevent Alzheimer's Disease? https://t.co/khXl3RjZW4 https://t.co/0PCkLCK8hA
Does Multiple Sclerosis prevent Alzheimer's Disease? https://t.co/khXl3RjZW4 https://t.co/0PCkLCK8hA
Does Multiple Sclerosis prevent Alzheimer's Disease? https://t.co/XmFCnQy1uA via @YouTube
https://t.co/PRuva3FAal
RT @WashUNeurology: A study from Matthew Brier, MD, PhD (@MatthewBrier), and other #WashUMed researchers found #MultipleSclerosis may prote…
RT @WashUNeurology: A study from Matthew Brier, MD, PhD (@MatthewBrier), and other #WashUMed researchers found #MultipleSclerosis may prote…
RT @WashUNeurology: A study from Matthew Brier, MD, PhD (@MatthewBrier), and other #WashUMed researchers found #MultipleSclerosis may prote…
RT @WashUNeurology: A study from Matthew Brier, MD, PhD (@MatthewBrier), and other #WashUMed researchers found #MultipleSclerosis may prote…
A study from Matthew Brier, MD, PhD (@MatthewBrier), and other #WashUMed researchers found #MultipleSclerosis may protect against #Alzheimers disease. These findings could point to new strategies to treat Alzheimer’s. https://t.co/MNCcIIpFI5 Read the study https://t.co/O5iZ5ZlJIe https://t.co/S7rZlSvGO7
RT @IJMSCtweets: "100 [indivs w/] #MultipleSclerosis, rate of amyloid-β plasma biomarker positivity was ~half rate in 300 nonMS matched on…
Unexpected Low Rate of Amyloid-β Pathology in Multiple Sclerosis Patients https://t.co/oc9jRY9jVi https://t.co/q9PnGLLO2I
RT @thmonk_pf: MS患者群では非MS対照群と比較してAlzheimer病理が有意に少ない APS2陽性率(7.1% vs 15.3%)、p-tau217比陽性率(9% vs 18.3%)が有意に低値 現時点ではメカニズムは不明、ただしMS症例の90%はDMTを…
RT @MIRimaging: First author @MatthewBrier, MD, PhD, @WashUNeurology assistant prof. and @BenzingerNeuro1 member, suggests that uncovering…
RT @Brandon_Beaber: Researchers from Washington University School of Medicine in St. Louis find that Alzheimer's disease is rare in people…
RT @Brandon_Beaber: Researchers from Washington University School of Medicine in St. Louis find that Alzheimer's disease is rare in people…
RT @Brandon_Beaber: Researchers from Washington University School of Medicine in St. Louis find that Alzheimer's disease is rare in people…
RT @MIRimaging: First author @MatthewBrier, MD, PhD, @WashUNeurology assistant prof. and @BenzingerNeuro1 member, suggests that uncovering…
First author @MatthewBrier, MD, PhD, @WashUNeurology assistant prof. and @BenzingerNeuro1 member, suggests that uncovering the protective elements in MS biology or patient genetics could lead to new strategies to treat Alzheimer’s. Read in @ANA_journals. https://t.co/iyK7snepHV
RT @Brandon_Beaber: Researchers from Washington University School of Medicine in St. Louis find that Alzheimer's disease is rare in people…
"100 [indivs w/] #MultipleSclerosis, rate of amyloid-β plasma biomarker positivity was ~half rate in 300 nonMS matched on age, sex, apolipoprotein E proteotype & cognitive status....results support that MS is associated w/ reduced #Alzheimer disease risk." https://t.co/bmqY0Qfa9J https://t.co/yXieREOFfF
RT @Dr_LPJ: Unexpected Low Rate of Amyloid-β Pathology in Multiple Sclerosis Patients https://t.co/UwJslQgXRZ
RT @Brandon_Beaber: Researchers from Washington University School of Medicine in St. Louis find that Alzheimer's disease is rare in people…
Unexpected Low Rate of Amyloid-β Pathology in Multiple Sclerosis Patients https://t.co/UwJslQgXRZ
Unexpected Low Rate of Amyloid-β Pathology in Multiple Sclerosis Patients https://t.co/FxnVdwAWjZ https://t.co/y9MHstKVWL
RT @NeuroscienceNew: “Unexpected low rate of amyloid-β pathology in multiple sclerosis patients” by Matthew Brier et al. Annals of Neurolog…
MS患者群では非MS対照群と比較してAlzheimer病理が有意に少ない APS2陽性率(7.1% vs 15.3%)、p-tau217比陽性率(9% vs 18.3%)が有意に低値 現時点ではメカニズムは不明、ただしMS症例の90%はDMTを行っているのでその影響は否定できない #MS #Alzheimers #papers https://t.co/FjDaWjki77 https://t.co/etINkki71k
RT @Brandon_Beaber: Researchers from Washington University School of Medicine in St. Louis find that Alzheimer's disease is rare in people…
RT @Brandon_Beaber: Researchers from Washington University School of Medicine in St. Louis find that Alzheimer's disease is rare in people…
RT @Brandon_Beaber: Researchers from Washington University School of Medicine in St. Louis find that Alzheimer's disease is rare in people…
RT @Brandon_Beaber: Researchers from Washington University School of Medicine in St. Louis find that Alzheimer's disease is rare in people…
RT @Brandon_Beaber: Researchers from Washington University School of Medicine in St. Louis find that Alzheimer's disease is rare in people…
RT @RachelHorne19: People with MS are far less likely to have Alzheimer's disease, a US study in Annals of Neurology says. The authors - le…
RT @Brandon_Beaber: Researchers from Washington University School of Medicine in St. Louis find that Alzheimer's disease is rare in people…
RT @Brandon_Beaber: Researchers from Washington University School of Medicine in St. Louis find that Alzheimer's disease is rare in people…
Researchers from Washington University School of Medicine in St. Louis find that Alzheimer's disease is rare in people with multiple sclerosis with a "rate of amyloid-β plasma biomarker positivity...approximately half the rate in 300 non-MS controls." https://t.co/FjpSKDShhS
RT @RachelHorne19: People with MS are far less likely to have Alzheimer's disease, a US study in Annals of Neurology says. The authors - le…
RT @RachelHorne19: People with MS are far less likely to have Alzheimer's disease, a US study in Annals of Neurology says. The authors - le…
RT @RachelHorne19: People with MS are far less likely to have Alzheimer's disease, a US study in Annals of Neurology says. The authors - le…
RT @RachelHorne19: People with MS are far less likely to have Alzheimer's disease, a US study in Annals of Neurology says. The authors - le…
People with MS are far less likely to have Alzheimer's disease, a US study in Annals of Neurology says. The authors - led by @MatthewBrier - found MS patients had far fewer amyloid plaques, a hallmark of Alzheimer's, vs adults without MS. @WUDeptMedicine https://t.co/2bVsEKYeeS
#Multiplesclerosis appears to protect against #Alzheimersdisease - #MS patients are less likely to have #amyloid plaques, a hallmark of #Alzheimer's disease, than adults without MS. https://t.co/XOR6H3qGcX https://t.co/3LvUyUY4Yx
RT @NeuroscienceNew: “Unexpected low rate of amyloid-β pathology in multiple sclerosis patients” by Matthew Brier et al. Annals of Neurolog…
RT @NeuroscienceNew: “Unexpected low rate of amyloid-β pathology in multiple sclerosis patients” by Matthew Brier et al. Annals of Neurolog…
RT @NeuroscienceNew: “Unexpected low rate of amyloid-β pathology in multiple sclerosis patients” by Matthew Brier et al. Annals of Neurolog…
“Unexpected low rate of amyloid-β pathology in multiple sclerosis patients” by Matthew Brier et al. Annals of Neurology https://t.co/JJRxPpnkjE 3/3
RT @WashUNeurology: A new study in @ANA_journals from Matthew Brier, MD, PhD (@MatthewBrier) & colleagues found Alzheimer disease pathology…
RT @WashUNeurology: A new study in @ANA_journals from Matthew Brier, MD, PhD (@MatthewBrier) & colleagues found Alzheimer disease pathology…
A new study in @ANA_journals from Matthew Brier, MD, PhD (@MatthewBrier) & colleagues found Alzheimer disease pathology is uncommon in #MultipleSclerosis patients based on blood biomarkers. The mechanism of this intriguing finding is being investigated. https://t.co/58ANVUcefQ
RT @NatRevNeurol: Unexpected Low Rate of Amyloid‐β Pathology in Multiple Sclerosis Patients https://t.co/J2z9HNSJVr
100 people with #MultipleSclerosis: "rate of #amyloid-β plasma #biomarker positivity was approx half rate in 300 non-MS controls matched on age, sex, apolipoprotein E proteotype, and cognitive status." https://t.co/bmqY0QeCkb @MatthewBrier @AnneHCross1 @WashUDPS @WashUNeurology https://t.co/yH6OAKMShV
RT @Pluchinolab: Unexpected Low Rate of Amyloid‐β Pathology in Multiple Sclerosis Patients - Brier - Annals of Neurology - Wiley Online Lib…
RT @NatRevNeurol: Unexpected Low Rate of Amyloid‐β Pathology in Multiple Sclerosis Patients https://t.co/J2z9HNSJVr
Unexpected Low Rate of Amyloid‐β Pathology in Multiple Sclerosis Patients - Brier - Annals of Neurology - Wiley Online Library https://t.co/GD7nsWtC1h
RT @NatRevNeurol: Unexpected Low Rate of Amyloid‐β Pathology in Multiple Sclerosis Patients https://t.co/J2z9HNSJVr
RT @NatRevNeurol: Unexpected Low Rate of Amyloid‐β Pathology in Multiple Sclerosis Patients https://t.co/J2z9HNSJVr
RT @NatRevNeurol: Unexpected Low Rate of Amyloid‐β Pathology in Multiple Sclerosis Patients https://t.co/J2z9HNSJVr
RT @NatRevNeurol: Unexpected Low Rate of Amyloid‐β Pathology in Multiple Sclerosis Patients https://t.co/J2z9HNSJVr
RT @NatRevNeurol: Unexpected Low Rate of Amyloid‐β Pathology in Multiple Sclerosis Patients https://t.co/J2z9HNSJVr
RT @NatRevNeurol: Unexpected Low Rate of Amyloid‐β Pathology in Multiple Sclerosis Patients https://t.co/J2z9HNSJVr
RT @NatRevNeurol: Unexpected Low Rate of Amyloid‐β Pathology in Multiple Sclerosis Patients https://t.co/J2z9HNSJVr
RT @NatRevNeurol: Unexpected Low Rate of Amyloid‐β Pathology in Multiple Sclerosis Patients https://t.co/J2z9HNSJVr
RT @NatRevNeurol: Unexpected Low Rate of Amyloid‐β Pathology in Multiple Sclerosis Patients https://t.co/J2z9HNSJVr
RT @NatRevNeurol: Unexpected Low Rate of Amyloid‐β Pathology in Multiple Sclerosis Patients https://t.co/J2z9HNSJVr
RT @NatRevNeurol: Unexpected Low Rate of Amyloid‐β Pathology in Multiple Sclerosis Patients https://t.co/J2z9HNSJVr
RT @NatRevNeurol: Unexpected Low Rate of Amyloid‐β Pathology in Multiple Sclerosis Patients https://t.co/J2z9HNSJVr
RT @NatRevNeurol: Unexpected Low Rate of Amyloid‐β Pathology in Multiple Sclerosis Patients https://t.co/J2z9HNSJVr
RT @NatRevNeurol: Unexpected Low Rate of Amyloid‐β Pathology in Multiple Sclerosis Patients https://t.co/J2z9HNSJVr
Unexpected Low Rate of Amyloid‐β Pathology in Multiple Sclerosis Patients https://t.co/J2z9HNSJVr
Now this is interesting on pathophysiological pathway implications and treatment avenues. First though, it’s worth looking into p-tau biomarkers to get a better picture. https://t.co/PrlJ12sRm2
Trend up+262: Brier MR, ..., Cross AH (Ann Neurol) __Unexpected Low Rate of Amyloid-β Pathology in Multiple Sclerosis Patients__ https://t.co/Pilcfq7pBH
RT @MS_ResearchDoc: A very provocative study led by @MatthewBrier and @AnneHCross1: Unexpected Low Rate of Amyloid‐β Pathology in Multiple…
RT @MS_ResearchDoc: A very provocative study led by @MatthewBrier and @AnneHCross1: Unexpected Low Rate of Amyloid‐β Pathology in Multiple…
RT @MS_ResearchDoc: A very provocative study led by @MatthewBrier and @AnneHCross1: Unexpected Low Rate of Amyloid‐β Pathology in Multiple…
A very provocative study led by @MatthewBrier and @AnneHCross1: Unexpected Low Rate of Amyloid‐β Pathology in Multiple Sclerosis Patients - Brier - Annals of Neurology - Wiley Online Library https://t.co/cVUDNROwws