Interesting new meta-regression suggests that strength gains are largely independent of intensity of effort, but optimal hypertrophy requires sets taken close to failure. Authors do an excellent job highlighting limitations of the exploratory approach https://t.co/pXCZU9hSc2
Exploring the Dose-Response Relationship Between Estimated Resistance Training Proximity to Failure, Strength Gain, and Muscle Hypertrophy: A Series of Meta-Regressions.
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May 2023 – Nov 2025Where it's discussed
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AI synopsis
What people are saying
Discussions surrounding the article consistently highlight the findings regarding the proximity to failure in resistance training. Phrases like 'failure is the best stimulus' and references to different muscle training outcomes indicate that the content is prompting thoughtful conversation. The choice of enthusiastic language alongside direct references to the study facilitates an engaging discourse that resonates well with the audience.
The majority of discussions lean toward supporting the findings of the publication, reflecting a consensus on the effectiveness of training close to failure for muscle hypertrophy.
Posts display a strong curiosity and relevance to fitness enthusiasts and professionals, indicating that the research has grabbed attention across the community.
Although some posts delve into specifics, such as technical terms like 'reps in reserve', the overall debate remains accessible to a wider audience.
Many participants perceive the publication as having significant implications for training practices, particularly concerning optimizing methods for hypertrophy and strength.
Abstract in brief
- The study examines how the proximity to failure (measured by repetitions in reserve or RIR) impacts strength gain and muscle growth during resistance training.
- Through a series of multilevel meta-regressions on existing research, the analysis finds that terminating sets closer to failure does not significantly enhance strength gains, as indicated by confidence intervals containing a null point.
- However, for muscle hypertrophy, the findings suggest that terminating sets closer to failure is associated with greater increases in muscle size, highlighting a clear negative relationship between RIR and muscle growth outcomes.
Top posts
Most liked on X and BlueskyMeta-analysis: going closer to failure
Exploring the Dose-Response Relationship Between Estimated Resistance Training Proximity to Failure, Strength Gain, and Muscle Hypertrophy: A Series of Meta-Regressions https://t.co/b39NbCGEEn https://t.co/tLPMXehlY6
https://t.co/AXr29AJOkM
筋トレでのRIR(各セットで何回余力を残すか)が低い(例:余力0回)ほど筋肥大効果は大きくなる傾向があるが、筋力向上効果はどんなRIRでもあまり変わらない可能性があることを示唆するメタ回帰。 https://t.co/VAgEzjRMq5
筋力の向上において 努力量(追い込み度合い)はほとんど無関係らしい https://t.co/6mvGiwW4lx
All mentions
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@Lunens__ placing here for lurkers: (the study) https://t.co/n2I2exDJcm https://t.co/IJ0zXgDZZM
新しいメタ分析では限界から遠い追い込みは筋肉の成長が減少することがわかった しかし、筋力については追い込みとの関連は見つからなかった。重量が停滞している種目はあえて追い込まずに多くのセットに挑戦したほうがいいかもしれません。 https://t.co/t77zWk1m2p
@Malthael02 Hay una meta regresión que dice que mientras menos reps en reserva haya hay más hipertrofia https://t.co/44mmKkdB3m
@hisholyhugeness Hi and thanks for the note! Dr. Mike is awesome, but some new research and meta-analysis have been published pushing the science further with the conclusion failure is the best stimulus: Robinson et al, https://t.co/Xco8M5ZIXU
“The dose-response relationship between proximity to failure and strength gain appears to differ from the relationship with muscle hypertrophy, with only the latter being meaningfully influenced by RIR.” https://t.co/PPepaFOZyh
@emesoul_ https://t.co/IFPy4mPPh8
Checkout the full study: “Exploring the Dose-Response Relationship Between Estimated Resistance Training Proximity to Failure, Strength Gain, and Muscle Hypertrophy: A Series of Meta-Regressions” –https://pubmed.ncbi.nlm.nih.gov/38970765/
RT @akito_ida: https://t.co/AXr29AJOkM
https://t.co/AXr29AJOkM
RT @drdairy50: optimal proximity to failure may differ between strength & muscle hypertrophy, caution is warranted on interpretation Explo…
RT @drdairy50: optimal proximity to failure may differ between strength & muscle hypertrophy, caution is warranted on interpretation Explo…
optimal proximity to failure may differ between strength & muscle hypertrophy, caution is warranted on interpretation Exploring the Dose-Response Relationship Between Estimated Resistance Training Proximity to Failure, Strength Gain, & Muscle Hypertrophy pubmed.ncbi.nlm.nih.gov/38970765/
optimal proximity to failure may differ between strength & muscle hypertrophy, caution is warranted on interpretation Exploring the Dose-Response Relationship Between Estimated Resistance Training Proximity to Failure, Strength Gain, & Muscle Hypertrophy https://t.co/btrj63gfxN
RT @AtualizadoSaber: (1) Publicação do estudo: Zourdos et al. (2024). Exploring the Dose–Response Relationship Between Estimated Resistan…
(1) Publicação do estudo: Zourdos et al. (2024). Exploring the Dose–Response Relationship Between Estimated Resistance Training Proximity to Failure, Strength Gain, and Muscle Hypertrophy: A Series of Meta-Regressions. Sports Medicine. https://t.co/z3vIW4KGZN
RT @taku0726_tr: 筋トレでのRIR(各セットで何回余力を残すか)が低い(例:余力0回)ほど筋肥大効果は大きくなる傾向があるが、筋力向上効果はどんなRIRでもあまり変わらない可能性があることを示唆するメタ回帰。 https://t.co/VAgEzjRMq5
RT @Bioqexercicio: Tá buscando aumentar o tamanho dos músculos? "muscle hypertrophy improves as sets are terminated closer to failure" "A…
れる傾向がありました。https://t.co/af4xqhHS8Z
New research finds that if you’re aiming for #muscle growth, training closer to failure (the point where you can’t do another rep) might be more effective. For strength, how close you push to failure doesn’t seem to matter as much. https://t.co/bFmKEFWk8L https://t.co/rZjr0GQrLT
RT @tiga_style: When to train to failure depends on your goal. For strength, it’s not very impactful; and could be recommended to avoid…
When to train to failure depends on your goal. For strength, it’s not very impactful; and could be recommended to avoid it to reduce fatigue on compound lifts. For muscle gain, training to failure or close to it can yield the best results. https://t.co/ueC5HzUZqD
@lxstlosty Exploring the Dose-Response Relationship Between Estimated Resistance Training Proximity to Failure, Strength Gain, and Muscle Hypertrophy: A Series of Meta-Regressions = failure is superior for hypertrophy training (in most cases)
Se rapprocher de l'échec entraîne une plus grande hypertrophie musculaire ; mais, pas nécessaire pour les gains de force : https://t.co/MV5OewJaEq
Se rapprocher de l'échec entraîne une plus grande hypertrophie musculaire ; mais, pas nécessaire pour les gains de force : https://t.co/MV5OewJaEq
限界まで追い込んだ際の筋肥大と筋力増強の用量反応関係に関するシステマティックレビュー RIR(予備反復回数)をもとに筋肥大反応と筋力増強(1RM)の反応を詳細に解析 有益な情報が多数含まれています 筋力は管理が複雑であることが分かります 今後の記事で取り上げます https://t.co/1TJ6A4jFpN https://t.co/a9IuvUXkSH
Exploring the Dose–Response Relationship Between Estimated Resistance Training Proximity to Failure, Strength Gain, and Muscle Hypertrophy: A Series of Meta-Regressions https://t.co/J8AomsCoLT
RT @BradSchoenfeld: Interesting new meta-regression suggests that strength gains are largely independent of intensity of effort, but optima…
RT @BradSchoenfeld: Interesting new meta-regression suggests that strength gains are largely independent of intensity of effort, but optima…
RT @BradSchoenfeld: Interesting new meta-regression suggests that strength gains are largely independent of intensity of effort, but optima…
RT @BradSchoenfeld: Interesting new meta-regression suggests that strength gains are largely independent of intensity of effort, but optima…
DEVO TREINAR ATÉ A FALHA? Um recente estudo nos ajuda a entender um pouco sobre o tema... https://t.co/xpv4mGkKpn
RT @BradSchoenfeld: Interesting new meta-regression suggests that strength gains are largely independent of intensity of effort, but optima…
RT @BradSchoenfeld: Interesting new meta-regression suggests that strength gains are largely independent of intensity of effort, but optima…
RT @BradSchoenfeld: Interesting new meta-regression suggests that strength gains are largely independent of intensity of effort, but optima…
https://t.co/wU9NfI8gB8
RT @BradSchoenfeld: Interesting new meta-regression suggests that strength gains are largely independent of intensity of effort, but optima…
RT @BradSchoenfeld: Interesting new meta-regression suggests that strength gains are largely independent of intensity of effort, but optima…
RT @BradSchoenfeld: Interesting new meta-regression suggests that strength gains are largely independent of intensity of effort, but optima…
RT @BradSchoenfeld: Interesting new meta-regression suggests that strength gains are largely independent of intensity of effort, but optima…
RT @BradSchoenfeld: Interesting new meta-regression suggests that strength gains are largely independent of intensity of effort, but optima…
https://t.co/TnfZH31l9H 追い込むと筋肥大に繋がるが筋力には繋がらない。どれくらいの重量を扱ったかは分からない。
RT @BradSchoenfeld: Interesting new meta-regression suggests that strength gains are largely independent of intensity of effort, but optima…
筋力の向上において 努力量(追い込み度合い)はほとんど無関係らしい https://t.co/6mvGiwW4lx
RT @BradSchoenfeld: Interesting new meta-regression suggests that strength gains are largely independent of intensity of effort, but optima…
RT @BradSchoenfeld: Interesting new meta-regression suggests that strength gains are largely independent of intensity of effort, but optima…
RT @BradSchoenfeld: Interesting new meta-regression suggests that strength gains are largely independent of intensity of effort, but optima…
RT @Bioqexercicio: Tá buscando aumentar o tamanho dos músculos? "muscle hypertrophy improves as sets are terminated closer to failure" "A…
RT @BradSchoenfeld: Interesting new meta-regression suggests that strength gains are largely independent of intensity of effort, but optima…
Exploring the Dose–Response Relationship Between Estimated Resistance Training Proximity to Failure, Strength Gain, and Muscle Hypertrophy: A Series of Meta-Regressions https://t.co/olH42xcqCl
RT @BradSchoenfeld: Interesting new meta-regression suggests that strength gains are largely independent of intensity of effort, but optima…
RT @BradSchoenfeld: Interesting new meta-regression suggests that strength gains are largely independent of intensity of effort, but optima…
RT @BradSchoenfeld: Interesting new meta-regression suggests that strength gains are largely independent of intensity of effort, but optima…
RT @BradSchoenfeld: Interesting new meta-regression suggests that strength gains are largely independent of intensity of effort, but optima…
RT @BradSchoenfeld: Interesting new meta-regression suggests that strength gains are largely independent of intensity of effort, but optima…
Tá buscando aumentar o tamanho dos músculos? "muscle hypertrophy improves as sets are terminated closer to failure" "A hipertrofia muscular melhora à medida que as séries são terminadas mais próximas da falha." https://t.co/xU9CJ4PtnI
RT @BradSchoenfeld: Interesting new meta-regression suggests that strength gains are largely independent of intensity of effort, but optima…
RT @BradSchoenfeld: Interesting new meta-regression suggests that strength gains are largely independent of intensity of effort, but optima…
"Exploring the Dose–Response Relationship Between Estimated Resistance Training Proximity to Failure, Strength Gain, and Muscle Hypertrophy: A Series of Meta-Regressions" — Read it on @ResearchGate: https://t.co/1NpCJmURJv
RT @BradSchoenfeld: Interesting new meta-regression suggests that strength gains are largely independent of intensity of effort, but optima…
RT @BradSchoenfeld: Interesting new meta-regression suggests that strength gains are largely independent of intensity of effort, but optima…
RT @BradSchoenfeld: Interesting new meta-regression suggests that strength gains are largely independent of intensity of effort, but optima…
RT @BradSchoenfeld: Interesting new meta-regression suggests that strength gains are largely independent of intensity of effort, but optima…
RT @BradSchoenfeld: Interesting new meta-regression suggests that strength gains are largely independent of intensity of effort, but optima…
RT @BradSchoenfeld: Interesting new meta-regression suggests that strength gains are largely independent of intensity of effort, but optima…
筋トレでのRIR(各セットで何回余力を残すか)が低い(例:余力0回)ほど筋肥大効果は大きくなる傾向があるが、筋力向上効果はどんなRIRでもあまり変わらない可能性があることを示唆するメタ回帰。 https://t.co/VAgEzjRMq5
RT @BradSchoenfeld: Interesting new meta-regression suggests that strength gains are largely independent of intensity of effort, but optima…
RT @BradSchoenfeld: Interesting new meta-regression suggests that strength gains are largely independent of intensity of effort, but optima…
RT @DanielBerglind: Meta-analysis: going closer to failure
RT @BradSchoenfeld: Interesting new meta-regression suggests that strength gains are largely independent of intensity of effort, but optima…
RT @BradSchoenfeld: Interesting new meta-regression suggests that strength gains are largely independent of intensity of effort, but optima…
RT @BradSchoenfeld: Interesting new meta-regression suggests that strength gains are largely independent of intensity of effort, but optima…
Exploración de cómo la cantidad de esfuerzo cerca del fallo muscular afecta la ganancia de fuerza y el crecimiento muscular durante el entrenamiento de FUERZA: un análisis detallado de varios estudios.
RT @BradSchoenfeld: Interesting new meta-regression suggests that strength gains are largely independent of intensity of effort, but optima…
RT @BradSchoenfeld: Interesting new meta-regression suggests that strength gains are largely independent of intensity of effort, but optima…
RT @BradSchoenfeld: Interesting new meta-regression suggests that strength gains are largely independent of intensity of effort, but optima…
RT @BradSchoenfeld: Interesting new meta-regression suggests that strength gains are largely independent of intensity of effort, but optima…
RT @BradSchoenfeld: Interesting new meta-regression suggests that strength gains are largely independent of intensity of effort, but optima…
RT @BradSchoenfeld: Interesting new meta-regression suggests that strength gains are largely independent of intensity of effort, but optima…
RT @BradSchoenfeld: Interesting new meta-regression suggests that strength gains are largely independent of intensity of effort, but optima…
RT @BradSchoenfeld: Interesting new meta-regression suggests that strength gains are largely independent of intensity of effort, but optima…
Interesting new meta-regression suggests that strength gains are largely independent of intensity of effort, but optimal hypertrophy requires sets taken close to failure. Authors do an excellent job highlighting limitations of the exploratory approach https://t.co/pXCZU9hSc2
レジスタンストレーニングで限界まで繰り返すことは、筋肉量の増加には効果的だけど、筋力の増強にはそうではない。 Exploring the Dose–Response Relationship Between Estimated Resistance Training Proximity to Failure, Strength Gain, and Muscle Hypertrophy https://t.co/JvT2g0MoEw
Timely, once again, after our prior posts i came across this analysis, @StrengthDebates "optimal proximity to failure may differ between strength and muscle hypertrophy outcomes" although, nuanced differences may exist...direct evidence req @MashElite https://t.co/kkIb6KAEmu
RT @DanielBerglind: Meta-analysis: going closer to failure
RT @DanielBerglind: Meta-analysis: going closer to failure
RT @DanielBerglind: Meta-analysis: going closer to failure
RT @DanielBerglind: Meta-analysis: going closer to failure
RT @DanielBerglind: Meta-analysis: going closer to failure
RT @DanielBerglind: Meta-analysis: going closer to failure
RT @DanielBerglind: Meta-analysis: going closer to failure
RT @DanielBerglind: Meta-analysis: going closer to failure
RT @DanielBerglind: Meta-analysis: going closer to failure
RT @DanielBerglind: Meta-analysis: going closer to failure
RT @DanielBerglind: Meta-analysis: going closer to failure
RT @Mattjones0203: Exploring the Dose-Response Relationship Between Estimated Resistance Training Proximity to Failure, Strength Gain, and…
RT @DanielBerglind: Meta-analysis: going closer to failure
RT @DanielBerglind: Meta-analysis: going closer to failure
RT @DanielBerglind: Meta-analysis: going closer to failure
RT @DanielBerglind: Meta-analysis: going closer to failure
RT @DanielBerglind: Meta-analysis: going closer to failure
RT @DanielBerglind: Meta-analysis: going closer to failure
RT @DanielBerglind: Meta-analysis: going closer to failure
RT @DanielBerglind: Meta-analysis: going closer to failure
RT @DanielBerglind: Meta-analysis: going closer to failure
RT @DanielBerglind: Meta-analysis: going closer to failure
RT @DanielBerglind: Meta-analysis: going closer to failure
RT @DanielBerglind: Meta-analysis: going closer to failure
RT @DanielBerglind: Meta-analysis: going closer to failure
Meta-analysis: going closer to failure
RT @Mattjones0203: Exploring the Dose-Response Relationship Between Estimated Resistance Training Proximity to Failure, Strength Gain, and…
Exploring the Dose-Response Relationship Between Estimated Resistance Training Proximity to Failure, Strength Gain, and Muscle Hypertrophy: A Series of Meta-Regressions https://t.co/2mNNW0Ms1u
Exploring the Dose–Response Relationship Between Estimated Resistance Training Proximity to Failure, Strength Gain, and Muscle Hypertrophy: A Series of Meta-Regressions https://t.co/URJC2dMtBg
Great to see another paper, final version, led by @zac__robinson Exploring the Dose–Response Relationship Between Estimated Resistance Training Proximity to Failure, Strength Gain, and Muscle Hypertrophy: A Series of Meta-Regressions
RT @Jozo_Grgic: Exploring the Dose-Response Relationship Between Estimated Resistance Training Proximity to Failure, Strength Gain, and Mus…
Zac has done a great job updating his preprint after feedback. Exploring the Dose-Response Relationship Between Estimated Resistance Training Proximity to Failure, Strength Gain, and Muscle Hypertrophy A Series of Meta-Regressions Check out the latest
Optimal hipertrofi için tükenişe gitmek şart değildir. -Robinson et al. (2023). Exploring the Dose-Response Relationship Between Estimated Resistance Training Proximity to Failure, Strength Gain, and Muscle Hypertrophy: A Series of Meta-Regressions
Exploring the Dose-Response Relationship Between Estimated Resistance Training Proximity to Failure, Strength Gain, and Muscle Hypertrophy https://t.co/qWbGbv6Ybo
RT @Jozo_Grgic: Exploring the Dose-Response Relationship Between Estimated Resistance Training Proximity to Failure, Strength Gain, and Mus…
RT @Jozo_Grgic: Exploring the Dose-Response Relationship Between Estimated Resistance Training Proximity to Failure, Strength Gain, and Mus…
RT @Jozo_Grgic: Exploring the Dose-Response Relationship Between Estimated Resistance Training Proximity to Failure, Strength Gain, and Mus…
RT @Jozo_Grgic: Exploring the Dose-Response Relationship Between Estimated Resistance Training Proximity to Failure, Strength Gain, and Mus…
RT @Jozo_Grgic: Exploring the Dose-Response Relationship Between Estimated Resistance Training Proximity to Failure, Strength Gain, and Mus…
RT @Jozo_Grgic: Exploring the Dose-Response Relationship Between Estimated Resistance Training Proximity to Failure, Strength Gain, and Mus…
RT @Jozo_Grgic: Exploring the Dose-Response Relationship Between Estimated Resistance Training Proximity to Failure, Strength Gain, and Mus…
RT @Jozo_Grgic: Exploring the Dose-Response Relationship Between Estimated Resistance Training Proximity to Failure, Strength Gain, and Mus…
RT @Jozo_Grgic: Exploring the Dose-Response Relationship Between Estimated Resistance Training Proximity to Failure, Strength Gain, and Mus…
RT @Jozo_Grgic: Exploring the Dose-Response Relationship Between Estimated Resistance Training Proximity to Failure, Strength Gain, and Mus…
RT @Jozo_Grgic: Exploring the Dose-Response Relationship Between Estimated Resistance Training Proximity to Failure, Strength Gain, and Mus…
RT @Jozo_Grgic: Exploring the Dose-Response Relationship Between Estimated Resistance Training Proximity to Failure, Strength Gain, and Mus…
RT @Jozo_Grgic: Exploring the Dose-Response Relationship Between Estimated Resistance Training Proximity to Failure, Strength Gain, and Mus…
RT @Jozo_Grgic: Exploring the Dose-Response Relationship Between Estimated Resistance Training Proximity to Failure, Strength Gain, and Mus…
RT @Jozo_Grgic: Exploring the Dose-Response Relationship Between Estimated Resistance Training Proximity to Failure, Strength Gain, and Mus…
Exploring the Dose-Response Relationship Between Estimated Resistance Training Proximity to Failure, Strength Gain, and Muscle Hypertrophy: A Series of Meta-Regressions https://t.co/b39NbCGEEn https://t.co/tLPMXehlY6
Think I missed sharing this great work from Zac Robinson: Exploring the Dose-Response Relationship Between Estimated Resistance Training Proximity to Failure, Strength Gain, and Muscle Hypertrophy: A Series of Meta-Regressions
RT @agingdoc1: Exploring the Dose-Response Relationship Between Estimated Resistance Training Proximity to Failure, Strength Gain, and Musc…
RT @agingdoc1: Exploring the Dose-Response Relationship Between Estimated Resistance Training Proximity to Failure, Strength Gain, and Musc…
Exploring the Dose-Response Relationship Between Estimated Resistance Training Proximity to Failure, Strength Gain, and Muscle Hypertrophy: A Series of Meta-Regressions