Three-dimensional genome architecture persists in a 52,000-year-old woolly mammoth skin sample https://t.co/x0XIkvJ5BX #biorxiv_genomic
Three-dimensional genome architecture persists in a 52,000-year-old woolly mammoth skin sample.
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Jul 2023 – Oct 2025Where it's discussed
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AI synopsis
What people are saying
The social discussions reveal a mix of admiration and curiosity, with posts praising the innovative approach, such as the use of PaleoHi-C, and contemplating the potential for reviving extinct species, indicated by phrases like 'amazing' and 'worth reading.' The tone shifts between technical appreciation and speculative excitement, showing deep engagement and recognition of the research's significance.
Most discussions support or are intrigued by the findings, with some expressing enthusiasm about potential implications.
The posts demonstrate high curiosity, mentioning techniques like PaleoHi-C and emphasizing the significance of preserving ancient DNA structures.
Participants delve into methodological details and speculate about broader impacts, indicating meaningful engagement.
Many highlight the groundbreaking nature of revealing genome architecture in ancient samples, suggesting these findings could shape future research.
Abstract in brief
- Researchers sequenced DNA from a 52,000-year-old woolly mammoth skin and found it retained its ancient genome structure.
- Using a technique called PaleoHi-C, they assembled the mammoth's genome into 28 large chromosome-length segments.
- The study revealed that the mammoth's genome organization is similar to that of Asian elephants, offering insights into genetic differences that may have influenced their evolution.
Top posts
Most liked on X and BlueskyYou don't want to miss the supplement, folks. Video S1 is an AI-generated song featuring shooting dehydrated beef liver with a shotgun https://t.co/wcIo6Uzr3E https://t.co/XRSlNLtb51
Three-dimensional genome architecture persists in a 52,000-year-old woolly mammoth skin sample "We began by creating a modified Hi-C protocol, dubbed PaleoHi-C, optimized for ancient samples ..." Sandoval-Velasco et al. bioRxiv https://t.co/yLx5GpieYm https://t.co/vpioFsv2dU
Amazing that long-range contact between DNA fragments is still maintained after 50k years. "Three-dimensional genome architecture persists in a 52,000-year-old woolly mammoth skin sample" https://t.co/Dtga5AzPwQ
Referencia: Three-dimensional genome architecture persists in a 52,000-year-old woolly mammoth skin sample. Marcela Sandoval-Velasco et al. Cell. JULY 11, 2024. DOI 10.1016/j.cell.2024.06.002
In the latest issue! Three-dimensional genome architecture persists in a 52,000-year-old woolly mammoth skin sample https://t.co/SGOSfCaMLn
All mentions
Reviving Extinct Animals: Can 52,000-Year-Old DNA Make It Possible?
In 2018, researchers discovered well-preserved mammoth remains in Russia, including DNA that retains its 3D structure. A recent study shows that ancient genome architecture persists, opening possibilities for…
Ancient Woolly Mammoth Chromosomes Preserved in 52,000-Year-Old Ice
Ancient Genome Structure of Woolly Mammoth Revealed by PaleoHi-C
Researchers sequenced DNA from a 52,000-year-old woolly mammoth skin, demonstrating retention of its ancient genome structure using PaleoHi-C. The genome is organized into 28 large chromosome segments, highlighting…
Ancient Mammoth Genome Reconstruction Reveals 3D Chromosome Structure
Researchers sequenced DNA from a 52,000-year-old mammoth skin and found it retained its ancient genome structure. Using PaleoHi-C, they assembled the genome into 28 large chromosome segments, providing insights into…
Reawakening Woolly Mammoths Using CRISPR Technology
Researchers sequenced DNA from a 52,000-year-old woolly mammoth skin and found it retained its ancient genome structure. The study reveals similarities to Asian elephants and offers insights into genetic differences…
Runner up would be: Three-dimensional genome architecture persists in a 52,000-year-old woolly mammoth skin sample, purely because of the supplemental video running over dehydrated beef liver with a car, shooting it with a shotgun, Ron Mathis hitting it with a fastball, ... cell.com/cms/10.1016/...
Three-dimensional genome architecture persists in a 52,000-year-old woolly mammoth skin sample: Cell https://t.co/JXij7rBs1b
Three-dimensional genome architecture persists in a 52,000-year-old woolly mammoth skin sample: Cell https://t.co/IdUjzkogBu
RT @profvrr: Starting Soon! ⏰ Nels and Vincent livestream an episode of This Week in Evolution on Wednesday, July 24 at 1pm EST. The paper…
Starting Soon! ⏰ Nels and Vincent livestream an episode of This Week in Evolution on Wednesday, July 24 at 1pm EST. The paper for discussion is "Three-dimensional genome architecture persists in a 52,000-year-old woolly mammoth skin sample."
https://t.co/D4H1no7CHQ
RT @evol_genomics: Three-dimensional genome architecture persists in a 52,000-year-old woolly mammoth skin sample https://t.co/0b6vYQBY8c @…
Three-dimensional genome architecture persists in a 52,000-year-old woolly mammoth skin sample https://t.co/0b6vYQBY8c @CellCellPress
¿ES POSIBLE REVIVIR ANIMALES EXTINTOS?
Three-dimensional genome architecture persists in a 52,000-year-old woolly mammoth skin sample: Cell https://t.co/QkgsHqstNc
¿ES POSIBLE REVIVIR ANIMALES EXTINTOS?
RT @doctorfision: Referencia: Three-dimensional genome architecture persists in a 52,000-year-old woolly mammoth skin sample. Marcela Sando…
Three-dimensional genome architecture persists in a 52,000-year-old woolly mammoth skin sample https://t.co/u3i1XxhU2i
RT @doctorfision: Referencia: Three-dimensional genome architecture persists in a 52,000-year-old woolly mammoth skin sample. Marcela Sando…
Referencia: Three-dimensional genome architecture persists in a 52,000-year-old woolly mammoth skin sample. Marcela Sandoval-Velasco et al. Cell. JULY 11, 2024. DOI 10.1016/j.cell.2024.06.002
Yes, the paper in Cell is cool and everything, but have you seen the accompanying music video? It sets a new bar
https://t.co/XHAqhf8cea
RT @CellCellPress: In the latest issue! Three-dimensional genome architecture persists in a 52,000-year-old woolly mammoth skin sample http…
Ben G Thomas Woolly Mammoth Chromosomes Found Frozen in Ice (52,000 Years Old!) | 7 Days of Science https://t.co/y0do5IGDI9
M. Sandoval-Velasco, et al., Three-dimensional genome architecture persists in a 52,000-year-old woolly mammoth skin sample. Cell 187, 3541–3562.e51 (2024). https://t.co/jqhkGEvtw4
RT @CellCellPress: In the latest issue! Three-dimensional genome architecture persists in a 52,000-year-old woolly mammoth skin sample http…
RT @CellCellPress: In the latest issue! Three-dimensional genome architecture persists in a 52,000-year-old woolly mammoth skin sample http…
In the latest issue! Three-dimensional genome architecture persists in a 52,000-year-old woolly mammoth skin sample https://t.co/SGOSfCaMLn
Amazing story- and check out Video 1 made with the help of generative AI. Three-dimensional genome architecture persists in a 52,000-year-old woolly mammoth skin sample: Cell https://t.co/bOvnOyvF08
Questions somewhat resolved by the film clip / rap of the paper showing the method in action https://t.co/72IW2j7Fqh
Reading a paper about wooly mammoth chromosome structure, and didn't think my question would be how exactly does one hit a tissue sample with a fastball? https://t.co/tjbM84UcGl https://t.co/jSI9r00A55
Three-dimensional genome architecture persists in a 52,000-year-old woolly mammoth skin sample #science #publication #research #journal https://t.co/vMcJpI9h2V
RT @alfonslopeztena: •Three-dimensional genome architecture persists in a 52,000-year-old woolly mammoth skin sample •PaleoHi-C makes it po…
RT @alfonslopeztena: •Three-dimensional genome architecture persists in a 52,000-year-old woolly mammoth skin sample •PaleoHi-C makes it po…
RT @kae_koganebuchi: 5万年前のマンモスでゲノムの3次元構造を解明!古いサンプルでこのような分析ができるとはおもしろい。論文中にマンモスのアイコンがいっぱい描かれていてかわいい
RT @kae_koganebuchi: 5万年前のマンモスでゲノムの3次元構造を解明!古いサンプルでこのような分析ができるとはおもしろい。論文中にマンモスのアイコンがいっぱい描かれていてかわいい
RT @Ribonucleotidic: Three-dimensional genome architecture persists in a 52,000-year-old woolly mammoth skin sample: Cell https://t.co/of8G…
RT @kae_koganebuchi: 5万年前のマンモスでゲノムの3次元構造を解明!古いサンプルでこのような分析ができるとはおもしろい。論文中にマンモスのアイコンがいっぱい描かれていてかわいい
Three-dimensional genome architecture persists in a 52,000-year-old woolly mammoth skin sample: Cell https://t.co/sPPsl1fkFl
RT @strnr: You don't want to miss the supplement, folks. Video S1 is an AI-generated song featuring shooting dehydrated beef liver with a s…
RT @strnr: You don't want to miss the supplement, folks. Video S1 is an AI-generated song featuring shooting dehydrated beef liver with a s…
RT @strnr: You don't want to miss the supplement, folks. Video S1 is an AI-generated song featuring shooting dehydrated beef liver with a s…
RT @strnr: You don't want to miss the supplement, folks. Video S1 is an AI-generated song featuring shooting dehydrated beef liver with a s…
RT @strnr: You don't want to miss the supplement, folks. Video S1 is an AI-generated song featuring shooting dehydrated beef liver with a s…
Three-dimensional genome architecture persists in a 52,000-year-old woolly mammoth skin sample https://t.co/nwCc0CDPV3 https://t.co/BPYUSlYOgH
Three-dimensional genome architecture persists in a 52,000-year-old woolly mammoth skin sample: Cell https://t.co/of8GUKST4V
Three-dimensional genome architecture persists in a 52,000-year-old woolly mammoth skin sample https://t.co/1Vq5VUHUJC
Three-dimensional genome architecture persists in a 52,000-year-old woolly mammoth skin sample https://t.co/7hRtIwlDZ9
すげーな、5万2000年前のマンモスゲノム解読。 下の方にあるビデオは、一般の方でも楽しめると思います Three-dimensional genome architecture persists in a 52,000-year-old wo... https://t.co/0APXSjjnTJ
Three-dimensional genome architecture persists in a 52,000-year-old woolly mammoth skin sample #science #publication #research #publications https://t.co/9jXfGiUA7O
Three-dimensional genome architecture persists in a 52,000-year-old woolly mammoth skin sample | Cell https://t.co/GGabebzJxj
Three-dimensional genome architecture persists in a 52,000-year-old woolly mammoth skin sample https://t.co/GHbIvSmX2F. Don’t skip the supplemental video https://t.co/wcIo6Uzr3E
Three-dimensional genome architecture persists in a 52,000-year-old woolly mammoth skin sample www.cell.com/cell/fulltex.... Don’t skip the supplemental video www.cell.com/cms/10.1016/...
Bibi voorspelt dat we nog tijdens ons leven kudde mammoeten int Zoniënwoud zien rondhuppelen
Nice work!
En jostain syystä saa aikaiseksi nättiä linkkiä Cell:n https://t.co/us9vDyFaxJ
ARTÍCULO REFERENCIA (acceso abierto) Three-dimensional genome architecture persists in a 52,000-year-old woolly mammoth skin sample https://t.co/tMmiTBRIfb vía #Cell https://t.co/KJnUympdoY
RT @strnr: You don't want to miss the supplement, folks. Video S1 is an AI-generated song featuring shooting dehydrated beef liver with a s…
RT @kae_koganebuchi: 5万年前のマンモスでゲノムの3次元構造を解明!古いサンプルでこのような分析ができるとはおもしろい。論文中にマンモスのアイコンがいっぱい描かれていてかわいい
Sandoval-Velasco et al. 2024. Three-dimensional genome architecture persists in a 52,000-year-old woolly mammoth skin sample. Cell. https://t.co/fF7AyjWX21 5200 万年前のケナガマンモス化石の染色体レベルでのゲノム解読。必見。
Worth reading
5万年前のマンモスでゲノムの3次元構造を解明!古いサンプルでこのような分析ができるとはおもしろい。論文中にマンモスのアイコンがいっぱい描かれていてかわいい
Three-dimensional genome architecture persists in a 52,000-year-old woolly mammoth skin sample: Cell https://t.co/IdUjzkogBu
@nvidia @MSFTResearch @awscloud some papers mentioned A maternal brain hormone that builds bone: https://t.co/jgV6SCjp3R Wooly Mammoth DNA: https://t.co/CznvVYwdHJ Molecular glue based sickle cell pill: https://t.co/qwL7Ast7qs Prov-Gigapath: https://t.co/B16QDyeOx3
Three-dimensional genome architecture persists in a 52,000-year-old woolly mammoth skin sample | Cell https://t.co/Q59csbN6CU
RT @strnr: You don't want to miss the supplement, folks. Video S1 is an AI-generated song featuring shooting dehydrated beef liver with a s…
Three-dimensional genome architecture persists in a 52,000-year-old woolly mammoth skin sample. #3Dgenome #WoollyMammothGenome @CellCellPress https://t.co/W5Ea8gCUMr
Three-dimensional genome architecture persists in a 52,000-year-old woolly mammoth skin sample: Cell https://t.co/A3dHae8U2U
RT @strnr: You don't want to miss the supplement, folks. Video S1 is an AI-generated song featuring shooting dehydrated beef liver with a s…
The paper in "Cell" the above "ABC News" article is based upon, & links to: “Three-dimensional genome architecture persists in a 52,000-year-old woolly mammoth skin sample” 2/2 https://t.co/16lxntR8uV
The paper in "Cell" the above "ABC News" article is based upon, & links to: “Three-dimensional genome architecture persists in a 52,000-year-old woolly mammoth skin sample” 2/2 https://t.co/16lxntQAFn
RT @strnr: You don't want to miss the supplement, folks. Video S1 is an AI-generated song featuring shooting dehydrated beef liver with a s…
You don't want to miss the supplement, folks. Video S1 is an AI-generated song featuring shooting dehydrated beef liver with a shotgun https://t.co/wcIo6Uzr3E https://t.co/XRSlNLtb51
Three-dimensional genome architecture persists in a 52,000-year-old woolly mammoth skin sample: Cell https://t.co/1fKiAZij9z
RT @alfonslopeztena: •Three-dimensional genome architecture persists in a 52,000-year-old woolly mammoth skin sample •PaleoHi-C makes it po…
RT @alfonslopeztena: •Three-dimensional genome architecture persists in a 52,000-year-old woolly mammoth skin sample •PaleoHi-C makes it po…
RT @alfonslopeztena: •Three-dimensional genome architecture persists in a 52,000-year-old woolly mammoth skin sample •PaleoHi-C makes it po…
If this isn't the start of Jurassic Park I dunno what is Three-dimensional genome architecture persists in a 52,000-year-old woolly mammoth skin sample: Cell https://t.co/mV4o9Kaj17
RT @alfonslopeztena: •Three-dimensional genome architecture persists in a 52,000-year-old woolly mammoth skin sample •PaleoHi-C makes it po…
RT @alfonslopeztena: •Three-dimensional genome architecture persists in a 52,000-year-old woolly mammoth skin sample •PaleoHi-C makes it po…
RT @alfonslopeztena: •Three-dimensional genome architecture persists in a 52,000-year-old woolly mammoth skin sample •PaleoHi-C makes it po…
•Three-dimensional genome architecture persists in a 52,000-year-old woolly mammoth skin sample •PaleoHi-C makes it possible to assemble the woolly mammoth’s genome •Chromatin compartments also persist, enabling study of mammoth gene expression https://t.co/sNSy7rxsUY https://t.co/u774fQk3x1
Three-dimensional genome architecture persists in a 52,000-year-old woolly mammoth skin sample https://t.co/FmrIHkxW7F
RT @biorxiv_genomic: Three-dimensional genome architecture persists in a 52,000-year-old woolly mammoth skin sample https://t.co/x0XIkvJ5B…
RT @gglinskii: Three-dimensional genome architecture persists in a 52,000-year-old woolly mammoth skin sample. https://t.co/CNgo0C4f5B
Three-dimensional genome architecture persists in a 52,000-year-old woolly mammoth skin sample. https://t.co/CNgo0C4f5B
RT @biorxiv_genomic: Three-dimensional genome architecture persists in a 52,000-year-old woolly mammoth skin sample https://t.co/x0XIkvJ5B…
RT @strnr: Three-dimensional genome architecture persists in a 52,000-year-old woolly mammoth skin sample https://t.co/IKtkaAxbGi
RT @strnr: Three-dimensional genome architecture persists in a 52,000-year-old woolly mammoth skin sample https://t.co/IKtkaAxbGi
RT @strnr: Three-dimensional genome architecture persists in a 52,000-year-old woolly mammoth skin sample https://t.co/IKtkaAxbGi
Three-dimensional genome architecture persists in a 52,000-year-old woolly mammoth skin sample https://t.co/IKtkaAxbGi
RT @boris_ctcf: Three-dimensional genome architecture persists in a 52,000-year-old woolly mammoth skin sample https://t.co/oRyil0jzN4 http…
RT @biorxiv_genomic: Three-dimensional genome architecture persists in a 52,000-year-old woolly mammoth skin sample https://t.co/x0XIkvJ5B…
RT @ShaiCarmi: Amazing that long-range contact between DNA fragments is still maintained after 50k years. "Three-dimensional genome archit…
Three-dimensional genome architecture persists in a 52,000-year-old woolly mammoth skin sample https://t.co/oRyil0jzN4 https://t.co/9pzMNYU6mu
RT @ShaiCarmi: Amazing that long-range contact between DNA fragments is still maintained after 50k years. "Three-dimensional genome archit…
Amazing that long-range contact between DNA fragments is still maintained after 50k years. "Three-dimensional genome architecture persists in a 52,000-year-old woolly mammoth skin sample" https://t.co/Dtga5AzPwQ
RT @biorxiv_genomic: Three-dimensional genome architecture persists in a 52,000-year-old woolly mammoth skin sample https://t.co/x0XIkvJ5B…
RT @biorxiv_genomic: Three-dimensional genome architecture persists in a 52,000-year-old woolly mammoth skin sample https://t.co/x0XIkvJ5B…
RT @biorxiv_genomic: Three-dimensional genome architecture persists in a 52,000-year-old woolly mammoth skin sample https://t.co/x0XIkvJ5B…
RT @doctorveera: Three-dimensional genome architecture persists in a 52,000-year-old woolly mammoth skin sample "We began by creating a m…
RT @biorxiv_genomic: Three-dimensional genome architecture persists in a 52,000-year-old woolly mammoth skin sample https://t.co/x0XIkvJ5B…
Three-dimensional genome architecture persists in a 52,000-year-old woolly mammoth skin sample "We began by creating a modified Hi-C protocol, dubbed PaleoHi-C, optimized for ancient samples ..." Sandoval-Velasco et al. bioRxiv https://t.co/yLx5GpieYm https://t.co/vpioFsv2dU
Three-dimensional genome architecture persists in a 52,000-year-old woolly mammoth skin sample
RT @biorxiv_genomic: Three-dimensional genome architecture persists in a 52,000-year-old woolly mammoth skin sample https://t.co/x0XIkvJ5B…
RT @biorxiv_genomic: Three-dimensional genome architecture persists in a 52,000-year-old woolly mammoth skin sample https://t.co/x0XIkvJ5B…
Three-dimensional genome architecture persists in a 52,000-year-old woolly mammoth skin sample https://t.co/AidLNMEf2Q https://t.co/Sn37A9fGzf
RT @biorxiv_genomic: Three-dimensional genome architecture persists in a 52,000-year-old woolly mammoth skin sample https://t.co/x0XIkvJ5B…
Three-dimensional genome architecture persists in a 52,000-year-old woolly mammoth skin sample https://t.co/ktcVaH7sfG
RT @biorxiv_genomic: Three-dimensional genome architecture persists in a 52,000-year-old woolly mammoth skin sample https://t.co/x0XIkvJ5B…
RT @biorxiv_genomic: Three-dimensional genome architecture persists in a 52,000-year-old woolly mammoth skin sample https://t.co/x0XIkvJ5B…
RT @biorxiv_genomic: Three-dimensional genome architecture persists in a 52,000-year-old woolly mammoth skin sample https://t.co/x0XIkvJ5B…
Three-dimensional genome architecture persists in a 52,000-year-old woolly mammoth skin sample https://t.co/x0XIkvJ5BX #biorxiv_genomic