JAMA Neurol September 2024 PMID 39008284

Substantia Nigra Pathology, Contact Sports Play, and Parkinsonism in Chronic Traumatic Encephalopathy.

Jason W Adams, Daniel Kirsch, Samantha M Calderazzo, Fatima Tuz-Zahra, Yorghos Tripodis, Jesse Mez, Michael L Alosco, Victor E Alvarez, Bertrand R Huber, Caroline Kubilus, Kerry A Cormier, Raymond Nicks, Madeline Uretsky, Evan Nair, Eva Kuzyk

Mentions

84
Peak: 18 in Jul 2024
across 5 sources since Jul 2024

Extended reach

828,149
potential audience

Total likes

333

Video views

2,864

Mentions per month

Jul 2024 – Mar 2025

Where it's discussed

  • News40 articles
  • X / Twitter36 posts
  • Facebook3 posts
  • Blogs3 articles
  • YouTube2 videos

AI synopsis

What people are saying

The overall discussions reflect an interest in the connection between contact sports, brain pathology, and parkinsonism, highlighted by phrases like 'unusual pathology' and 'significant connection,' which indicate engagement and recognition of potential implications for sports safety and neurological research.

AgreementModerate agreement

Most posts acknowledge the research’s findings and seem to support the link between contact sports-related brain injuries and parkinsonism.

InterestModerate interest

Generally, the discussions show moderate interest, with many posts emphasizing the significance of the findings and potential health implications.

EngagementModerate engagement

Several posts reference specific data points, such as the 25% prevalence rate, and mention the unusual pathology associated with CTE, indicating thoughtful engagement.

ImpactModerate impact

The posts suggest the study’s results could influence understanding and awareness of sports-related brain injuries and their long-term effects.

Abstract in brief

  • Parkinsonism is often linked to chronic traumatic encephalopathy (CTE) caused by repetitive head injuries, but the exact causes of parkinsonism in CTE patients are not fully understood.
  • This study examined brain donors diagnosed with CTE to determine how often parkinsonism occurs and its relationship with brain damage due to past sports-related injuries.
  • Results indicated that 24.7% of CTE participants experienced parkinsonism, which was associated with older age, higher dementia rates, and more severe stages of CTE, suggesting a significant connection between the severity of CTE and parkinsonism.

Top posts

Most liked on X and Bluesky
JAMA Neurology
@JAMANeuro · X

Study of deceased contact sports athletes with CTE reports that nearly 25% had parkinsonism during life. Most had an unusual pathology related to CTE and football play and not the typical Lewy body pathology found in most cases of Parkinson disease. https://t.co/D8vAvJM14Z https://t.co/ZHANobYbZV

Jul 15, 2024 · 87 likes · 31 shares · 65,067 followers View post →
JAMA Neurology
@JAMANeuro · X

Study of deceased contact sports athletes with CTE reports that nearly 25% had parkinsonism during life. Most had an unusual pathology related to CTE and football play and not the typical Lewy body pathology found in most cases of Parkinson disease. https://t.co/183CBkOT1I https://t.co/YrJVKPidsZ

Sep 14, 2024 · 70 likes · 34 shares · 65,067 followers View post →
JAMA
@JAMA_current · X

From @JAMANeuro: Study of deceased contact sports athletes w/ CTE reports that nearly 25% had parkinsonism during life. Most had an unusual pathology related to CTE & football play & not the typical Lewy body pathology found in most cases of Parkinson https://t.co/oNOsN2u1Cl https://t.co/bxY3u5PoUA

Jul 15, 2024 · 40 likes · 15 shares · 488,091 followers View post →
Gastón F Rodríguez
@GastonFRodrigu1 · X

Patología de Substantia Nigra, juego deportivo de contacto y parkinsonismo en la encefalopatía traumática crónica | Neurología | Neurología JAMA | Red JAMA https://t.co/66vXez6Ppf

Jul 16, 2024 · 4 likes · 2 shares · 1,155 followers View post →
Gustavo Domeniconi
@gdomeni · X

Substantia Nigra Pathology, Contact Sports Play, and Parkinsonism in Chronic Traumatic Encephalopathy | Neurology | JAMA Neurology #TBI ⁦@ociredeF_MD⁩ https://t.co/ToSW4C0KU8

Sep 15, 2024 · 3 likes · 2 shares · 904 followers View post →
TBI One Love/James Durham
@tbionelove · X

A new study from BU CTE Center was with 481 brain donors of contact sports who died with #CTE. 25% developed movement symptoms that looked like Parkinson's disease. Learn more: https://t.co/b6dCypgxJM One love #braininjury #awareness #invisible #disability https://t.co/UqfjyuVdGH

Jul 16, 2024 · 1 like · 832 followers View post →

All mentions

Asociación Parkinson Madrid
@ParkinsonMadrid · X

Substantia nigra pathology, contact sports play, and #parkinsonism in chronic traumatic encephalopathy: https://t.co/bxNNVoCBqx via @JAMANetwork

Sep 16, 2024 · 6,566 followers View post →
Neuro Criticos
@neurointensivos · X

RT @gdomeni: Substantia Nigra Pathology, Contact Sports Play, and Parkinsonism in Chronic Traumatic Encephalopathy | Neurology | JAMA Neuro…

Sep 15, 2024 · 2 shares · 2,815 followers View post →
Federico Rodríguez Lucci
@ociredeF_MD · X

RT @gdomeni: Substantia Nigra Pathology, Contact Sports Play, and Parkinsonism in Chronic Traumatic Encephalopathy | Neurology | JAMA Neuro…

Sep 15, 2024 · 2 shares · 313 followers View post →
Gustavo Domeniconi
@gdomeni · X

Substantia Nigra Pathology, Contact Sports Play, and Parkinsonism in Chronic Traumatic Encephalopathy | Neurology | JAMA Neurology #TBI ⁦@ociredeF_MD⁩ https://t.co/ToSW4C0KU8

Sep 15, 2024 · 3 likes · 2 shares · 904 followers View post →
Tom Varghese Jr. MD, MS, MBA, FACS, MAMSE
@TomVargheseJr · X

RT @JAMANeuro: Study of deceased contact sports athletes with CTE reports that nearly 25% had parkinsonism during life. Most had an unusual…

Sep 14, 2024 · 34 shares · 25,773 followers View post →
Tatiana Prowell, MD
@tmprowell · X

RT @JAMANeuro: Study of deceased contact sports athletes with CTE reports that nearly 25% had parkinsonism during life. Most had an unusual…

Sep 14, 2024 · 34 shares · 60,287 followers View post →
Sahit Nallani Menon
@sahitmenon · X

RT @JAMANeuro: Study of deceased contact sports athletes with CTE reports that nearly 25% had parkinsonism during life. Most had an unusual…

Sep 14, 2024 · 34 shares · 714 followers View post →
ICUsteps
@ICUsteps · X

RT @JAMANeuro: Study of deceased contact sports athletes with CTE reports that nearly 25% had parkinsonism during life. Most had an unusual…

Sep 14, 2024 · 34 shares · 9,033 followers View post →
Jordan Vajda MD MPH MA MDiv
@jordan_vajda · X

RT @JAMANeuro: Study of deceased contact sports athletes with CTE reports that nearly 25% had parkinsonism during life. Most had an unusual…

Sep 14, 2024 · 34 shares · 485 followers View post →
Dr Dorina Cadar
@DorinaCadar · X

RT @JAMANeuro: Study of deceased contact sports athletes with CTE reports that nearly 25% had parkinsonism during life. Most had an unusual…

Sep 14, 2024 · 34 shares · 1,946 followers View post →
Pierre Mégevand
@pierre_vanmedge · X

RT @JAMANeuro: Study of deceased contact sports athletes with CTE reports that nearly 25% had parkinsonism during life. Most had an unusual…

Sep 14, 2024 · 34 shares · 1,302 followers View post →
Dale Schenck
@tocatchahacker_ · X

RT @JAMANeuro: Study of deceased contact sports athletes with CTE reports that nearly 25% had parkinsonism during life. Most had an unusual…

Sep 14, 2024 · 34 shares · 1,137 followers View post →
Michael Okun
@MichaelOkun · X

RT @JAMANeuro: Study of deceased contact sports athletes with CTE reports that nearly 25% had parkinsonism during life. Most had an unusual…

Sep 14, 2024 · 34 shares · 38,508 followers View post →
Jamie Clarke, MD, MS
@JamieClarkeRad · X

RT @JAMANeuro: Study of deceased contact sports athletes with CTE reports that nearly 25% had parkinsonism during life. Most had an unusual…

Sep 14, 2024 · 34 shares · 2,035 followers View post →
Neuron Atlas
@NeuronAtlas · X

RT @JAMANeuro: Study of deceased contact sports athletes with CTE reports that nearly 25% had parkinsonism during life. Most had an unusual…

Sep 14, 2024 · 34 shares · 75 followers View post →
Robert Howard also on BlueSky as @ProfRobHoward
@ProfRobHoward · X

RT @JAMANeuro: Study of deceased contact sports athletes with CTE reports that nearly 25% had parkinsonism during life. Most had an unusual…

Sep 14, 2024 · 34 shares · 18,034 followers View post →
ong beng hooi
@ongbenghooi1 · X

RT @JAMANeuro: Study of deceased contact sports athletes with CTE reports that nearly 25% had parkinsonism during life. Most had an unusual…

Sep 14, 2024 · 34 shares · 534 followers View post →
JAMA Neurology
@JAMANeuro · X

Study of deceased contact sports athletes with CTE reports that nearly 25% had parkinsonism during life. Most had an unusual pathology related to CTE and football play and not the typical Lewy body pathology found in most cases of Parkinson disease. https://t.co/183CBkOT1I https://t.co/YrJVKPidsZ

Sep 14, 2024 · 70 likes · 34 shares · 65,067 followers View post →
@investigando
@rocatanho · X

Impactos cefálicos repetitivos pueden incitar procesos neuropatológicos que conducen a síntomas de parkinsonismo en pacientes con encefalopatía traumática crónica #CTE. #contactsports #substantianigra https://t.co/i9JRAKdfQu

Jul 22, 2024 · 400 followers View post →
TBI One Love/James Durham
@tbionelove · X

A new study from BU CTE Center was with 481 brain donors of contact sports who died with #CTE. 25% developed movement symptoms that looked like Parkinson's disease. Learn more: https://t.co/b6dCypgxJM One love #braininjury #awareness #invisible #disability https://t.co/UqfjyuVdGH

Jul 16, 2024 · 1 like · 832 followers View post →
SAMM
@pipasMoreno · X

RT @GastonFRodrigu1: Patología de Substantia Nigra, juego deportivo de contacto y parkinsonismo en la encefalopatía traumática crónica | Ne…

Jul 16, 2024 · 2 shares · 860 followers View post →
Ofabpix
@ascarislum · X

RT @GastonFRodrigu1: Patología de Substantia Nigra, juego deportivo de contacto y parkinsonismo en la encefalopatía traumática crónica | Ne…

Jul 16, 2024 · 2 shares · 114 followers View post →
Gastón F Rodríguez
@GastonFRodrigu1 · X

Patología de Substantia Nigra, juego deportivo de contacto y parkinsonismo en la encefalopatía traumática crónica | Neurología | Neurología JAMA | Red JAMA https://t.co/66vXez6Ppf

Jul 16, 2024 · 4 likes · 2 shares · 1,155 followers View post →
Gustavo Domeniconi
@gdomeni · X

RT @JAMANeuro: Study of deceased contact sports athletes with CTE reports that nearly 25% had parkinsonism during life. Most had an unusual…

Jul 15, 2024 · 31 shares · 904 followers View post →
Rarely Wright
@2Rarely · X

Jason W. Adams et al, Substantia Nigra Pathology, Contact Sports Play, and Parkinsonism in Chronic Traumatic Encephalopathy, JAMA Neurology (2024). DOI: 10.1001/jamaneurol.2024.2166 https://t.co/PzvlE8Q7sx

Jul 15, 2024 · 1,538 followers View post →
ong beng hooi
@ongbenghooi1 · X

RT @JAMA_current: From @JAMANeuro: Study of deceased contact sports athletes w/ CTE reports that nearly 25% had parkinsonism during life. M…

Jul 15, 2024 · 15 shares · 534 followers View post →
Researching the Brain
@Brain_Database · X

RT @JAMANeuro: Study of deceased contact sports athletes with CTE reports that nearly 25% had parkinsonism during life. Most had an unusual…

Jul 15, 2024 · 31 shares · 1,038 followers View post →
KoupeDeVille
@KoupeDeVille · X

RT @JAMA_current: From @JAMANeuro: Study of deceased contact sports athletes w/ CTE reports that nearly 25% had parkinsonism during life. M…

Jul 15, 2024 · 15 shares · 236 followers View post →
Concussion Legacy Foundation
@ConcussionLF · X

RT @JAMA_current: From @JAMANeuro: Study of deceased contact sports athletes w/ CTE reports that nearly 25% had parkinsonism during life. M…

Jul 15, 2024 · 15 shares · 21,810 followers View post →
Robbi Michale Holloway Powell
@MichaleH1967 · X

RT @JAMA_current: From @JAMANeuro: Study of deceased contact sports athletes w/ CTE reports that nearly 25% had parkinsonism during life. M…

Jul 15, 2024 · 15 shares · 1,077 followers View post →
Charles Jourdan Reyes, Ph.D.
@reyes_jourdan · X

RT @JAMANeuro: Study of deceased contact sports athletes with CTE reports that nearly 25% had parkinsonism during life. Most had an unusual…

Jul 15, 2024 · 31 shares · 624 followers View post →
Karl C. Mayer
@Neuro24de · X

RT @JAMANeuro: Study of deceased contact sports athletes with CTE reports that nearly 25% had parkinsonism during life. Most had an unusual…

Jul 15, 2024 · 31 shares · 1,318 followers View post →
Pedro Pinzon B.
@pedroa_pinzon · X

RT @JAMANeuro: Study of deceased contact sports athletes with CTE reports that nearly 25% had parkinsonism during life. Most had an unusual…

Jul 15, 2024 · 31 shares · 437 followers View post →
ChiRadio™️©️
@chiradio · X

RT @JAMA_current: From @JAMANeuro: Study of deceased contact sports athletes w/ CTE reports that nearly 25% had parkinsonism during life. M…

Jul 15, 2024 · 15 shares · 2,195 followers View post →
JAMA
@JAMA_current · X

From @JAMANeuro: Study of deceased contact sports athletes w/ CTE reports that nearly 25% had parkinsonism during life. Most had an unusual pathology related to CTE & football play & not the typical Lewy body pathology found in most cases of Parkinson https://t.co/oNOsN2u1Cl https://t.co/bxY3u5PoUA

Jul 15, 2024 · 40 likes · 15 shares · 488,091 followers View post →
JAMA Neurology
@JAMANeuro · X

Study of deceased contact sports athletes with CTE reports that nearly 25% had parkinsonism during life. Most had an unusual pathology related to CTE and football play and not the typical Lewy body pathology found in most cases of Parkinson disease. https://t.co/D8vAvJM14Z https://t.co/ZHANobYbZV

Jul 15, 2024 · 87 likes · 31 shares · 65,067 followers View post →