PubHawk
Psychiatry Clin Neurosci September 2024 PMID 39041066

Arachidonic acid-derived dihydroxy fatty acids in neonatal cord blood relate symptoms of autism spectrum disorders and social adaptive functioning: Hamamatsu Birth Cohort for Mothers and Children (HBC Study).

Takaharu Hirai, Naoko Umeda, Taeko Harada, Akemi Okumura, Chikako Nakayasu, Takayo Ohto-Nakanishi, Kenji J Tsuchiya, Tomoko Nishimura, Hideo Matsuzaki

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Mentions

210
Peak: 72 in Aug 2024
across 6 sources since Jul 2024

Extended reach

1,267,229
potential audience

Total likes

8,367

Video views

205,149

Mentions per month

Jul 2024 – Sep 2025

Where it's discussed

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AI synopsis

What people are saying

Several discussions highlight the study's findings, with comments like 'a significant connection between increase in PUFA fatty acids' suggesting interest in the details. The use of phrases such as 'could improve early diagnosis and prevention' indicates a serious consideration of the research's potential implications. Additionally, remarks regarding the correlation between specific fatty acids and autism symptoms reflect a tone of urgency and importance, enhancing overall engagement with the publication.

AgreementModerate agreement

Most discussions express a level of support for the findings of the publication, acknowledging the potential link between fatty acids and autism.

InterestHigh interest

The majority of posts show strong curiosity and engagement with the topic, indicating that participants find the subject compelling.

EngagementModerate engagement

While some discussions reference the methodologies and implications of the research, many seem to remain at a surface level.

ImpactHigh impact

Users perceive the publication as having significant implications for early diagnosis and prevention strategies in relation to autism.

Abstract in brief

  • The study explored the relationship between dihydroxy fatty acids derived from arachidonic acid in neonatal cord blood and symptoms of autism spectrum disorder (ASD) and social functioning in children.
  • High levels of the specific fatty acid 1112diHETrE were linked to increased severity of ASD symptoms and socialization impairment, while lower levels of 89diHETrE were associated with repetitive behaviors.
  • Findings indicate that the balance of certain fatty acids during fetal development plays a critical role in the risk of ASD and suggests the need for further research on the impacts of diol metabolites on neurodevelopment.
Read the full abstract

Top posts

Most liked on X and Bluesky
Andra
@BioavailableNd · X

Research Link: https://t.co/8jMJhBMjrQ

Aug 4, 2024 · 209 likes · 45 shares · 139,285 followers View post →
Seed Oil Scout
@SeedOilScout · X

@hubermanlab 2024: In 200 Japanese children, PUFA metabolite AA in neonatal cord blood was STRONGLY correlated with autism symptom severity. https://t.co/UDOLhp3XfI https://t.co/TB0NZhy4oS

Dec 10, 2024 · 160 likes · 6 shares · 38,623 followers View post →
Diljan Mansoor MD
@DiljanMansoor · X

https://t.co/C7lsDygF3S Japanese Scientists discovered a significant connection between increase in PUFA fatty acids in umbilical cord blood and severity autism symptoms in children. @LDLSkeptic @FructoseNo @lowcarbGP @drjasonfung

Aug 6, 2024 · 20 likes · 5 shares · 4,320 followers View post →
Digital Brain
@yourdigitalbrain.bsky.social · Bluesky

A Japanese study suggests that certain fatty acids in umbilical cord blood may be linked to the development of autism, opening the door to earlier diagnoses and potential preventive measures during pregnancy. DOI: 10.1111/pcn.13710

Jun 10, 2025 · 14 likes · 6 shares View post →
exfatloss
@exfatloss · X

Seed oils cause autism lol https://t.co/WOqVff5xhT

Jul 31, 2024 · 10 likes · 6,674 followers View post →
Neuroscience News
@NeuroscienceNew · X

“Arachidonic acid-derived dihydroxy fatty acids in neonatal cord blood relate symptoms of autism spectrum disorders and social adaptive functioning: Hamamatsu Birth Cohort for Mothers and Children (HBC Study)” by Hideo Matsuzaki et al. Psychiatry and Clinical Neurosciences

Jul 29, 2024 · 5 likes · 2 shares · 505,522 followers View post →

All mentions

Classimo
@Classimo3 · X

@cremieuxrecueil Are you familiar with this study? Would love to hear your thoughts: DOI:10.1111/pcn.13710 https://t.co/sLGcytQxeO

Sep 24, 2025 · 1 like · 239 followers View post →
Cerebro Digital
@cerebrodigital.net · Bluesky

Un estudio en Japón halló un posible vínculo entre ácidos grasos en sangre del cordón umbilical y el autismo, lo que podría mejorar el diagnóstico temprano y la prevención durante el embarazo. DOI: 10.1111/pcn.13710 Descubre más aquí: cerebrodigital.net/estudio-...

Sep 1, 2025 · 3 likes View post →
Cerebro Digital
@cerebrodigital.net · Bluesky

Un estudio en Japón encontró una posible relación entre ácidos grasos en sangre del cordón umbilical y el desarrollo del autismo, lo que podría mejorar el diagnóstico temprano y la prevención durante el embarazo. DOI: 10.1111/pcn.13710 Te explicamos aquí:

Aug 8, 2025 · 3 likes View post →
David
@davidmmoss.bsky.social · Bluesky

Did you hear that Japanese scientists found the cause of autism? That's the topic for this week's video! youtu.be/iP3pucodkL0

Jul 2, 2025 View post →
accommodate-this.bsky.social
@accommodate-this.bsky.social · Bluesky

Did you hear that Japanese scientists found the cause of autism? That's the topic for this week's video! youtu.be/iP3pucodkL0

Jul 2, 2025 View post →
Digital Brain
@digitalbrain01 · X

A Japanese study suggests that certain fatty acids in umbilical cord blood may be linked to the development of autism, opening the door to earlier diagnoses and potential preventive measures during pregnancy. DOI: 10.1111/pcn.13710 https://t.co/TQBd09pyjH

Jun 10, 2025 · 1 followers View post →
Digital Brain
@yourdigitalbrain.bsky.social · Bluesky

A Japanese study suggests that certain fatty acids in umbilical cord blood may be linked to the development of autism, opening the door to earlier diagnoses and potential preventive measures during pregnancy. DOI: 10.1111/pcn.13710

Jun 10, 2025 · 14 likes · 6 shares View post →
Juan Manuel González
@jmgosan · X

@followero Publicaban en algunos estudios que había correlación entre ciertas conductas y metabolitos de ácidos grasos en el cordón umbilical: https://t.co/AnuWsbSuMH

Jan 27, 2025 · 329 followers View post →
Socialista de Xiaomi
@_poxatony · X

@proudsouthernsc @whatsap36898821 @brasilemfuria Leia a pesquisa, anjo. O estudo mostra correlação entre metabólitos no sangue do cordão umbilical e sintomas de autismo, mas não prova causalidade devido à natureza observacional e falta de intervenções experimentais. É só ler a pesquisa... https://t.co/lnDrqA6K1i

Jan 9, 2025 · 1 like · 130 followers View post →
Jerry Downhouse
@dd10432_jerry · X

"Autism spectrum disorder (ASD) is associated w/ abnormal lipid metabolism, such as a high total ratio of omega-6 to omega-3 in polyunsaturated fatty acids (PUFAs). ...this study provide important insight into the role of diHETrE & ASD pathophysiology."https://t.co/5jjKJOoRfQ

Dec 19, 2024 · 146 followers View post →
Gerd Moe-Behrens
@GerdMoeBehrens · X

Arachidonic acid-derived dihydroxy fatty acids in neonatal cord blood relate symptoms of autism spectrum disorders and social adaptive functioning: Hamamatsu Birth Cohort for Mothers and Children (HBC Study) https://t.co/hWHWzMd9F2

Dec 19, 2024 · 2,446 followers View post →
Sara McGrath
@saramcgrath77 · X

RT @SeedOilScout: @hubermanlab 2024: In 200 Japanese children, PUFA metabolite AA in neonatal cord blood was STRONGLY correlated with autis…

Dec 10, 2024 · 6 shares · 947 followers View post →
Anthony Stine
@pontificatormax · X

RT @SeedOilScout: @hubermanlab 2024: In 200 Japanese children, PUFA metabolite AA in neonatal cord blood was STRONGLY correlated with autis…

Dec 10, 2024 · 6 shares · 39,404 followers View post →
Elizabeth T
@TElizabethPhD · X

RT @SeedOilScout: @hubermanlab 2024: In 200 Japanese children, PUFA metabolite AA in neonatal cord blood was STRONGLY correlated with autis…

Dec 10, 2024 · 6 shares · 2,503 followers View post →
Diamond Truths
@DiamondTruths_ · X

RT @SeedOilScout: @hubermanlab 2024: In 200 Japanese children, PUFA metabolite AA in neonatal cord blood was STRONGLY correlated with autis…

Dec 10, 2024 · 6 shares · 151 followers View post →
Mark
@MarkusOfCoast · X

RT @SeedOilScout: @hubermanlab 2024: In 200 Japanese children, PUFA metabolite AA in neonatal cord blood was STRONGLY correlated with autis…

Dec 10, 2024 · 6 shares · 225 followers View post →
Seed Oil Scout
@SeedOilScout · X

@hubermanlab 2024: In 200 Japanese children, PUFA metabolite AA in neonatal cord blood was STRONGLY correlated with autism symptom severity. https://t.co/UDOLhp3XfI https://t.co/TB0NZhy4oS

Dec 10, 2024 · 160 likes · 6 shares · 38,623 followers View post →
OhSoDull
@OhSoDullHQ · X

@marksandspencer @MJtweetings https://t.co/Zr3Ma94zbI

Oct 20, 2024 · 536 followers View post →
OhSoDull
@OhSoDullHQ · X

RT @OhSoDullHQ: @marksandspencer SEED OILS STUDY! Are you killing your customers? https://t.co/Zr3Ma94zbI

Oct 20, 2024 · 1 share · 536 followers View post →
Andrea Hurley
@andreahurley606 · X

@FAWADBAHAWAL @LeadingReport This IS science. This research indicates inflammatory cytokines may be responsible for ASD. ~20% of Americans are living with Mast Cell Activation Syndrome, which is sometimes triggered by vaccines (among a multitude of other things.) https://t.co/3P4xJhpV57

Sep 3, 2024 · 1 like · 133 followers View post →
Andrea Hurley
@andreahurley606 · X

@Cynical_Reality @LeadingReport Link : https://t.co/3P4xJhpV57

Sep 3, 2024 · 133 followers View post →
StillerNP
@LogosFNP · X

Arachidonic acid‐derived dihydroxy fatty acids in neonatal cord blood relate symptoms of autism spectrum disorders and social adaptive functioning: Hamamatsu Birth Cohort for Mothers and Children (HBC Study) - Hirai - Psychiatry and Clinical Neuroscience https://t.co/gOmBUEXbyo

Aug 20, 2024 · 30 followers View post →
Jim Dean
@JimDean31126390 · X

Autism spectrum disorder (ASD) is associated with abnormal lipid metabolism, such as a high total ratio of omega-6 to omega-3 in polyunsaturated fatty acids (PUFAs). https://t.co/pEl40eKz8K

Aug 20, 2024 · 156 followers View post →
Dr. Miladys Cepero-Perez, NBCT
@Mcepero · X

https://t.co/lge6VuhgIi nic acid‐derived dihydroxy fatty acids in neonatal cord blood relate symptoms of autism spectrum disorders and social adaptive functioning: Hamamatsu Birth Cohort for Mothers and Children (HBC Study) -

Aug 17, 2024 · 1,063 followers View post →
KetoCN
@KetoCNOfficial · X

RT @BioavailableNd: Research Link: https://t.co/8jMJhBMjrQ

Aug 6, 2024 · 45 shares · 45 followers View post →
Mamiko_Yamada
@No_hpvv_kanagaw · X

RT @carolynkidman: Arachidonic acid-derived dihydroxy fatty acids in neonatal cord blood relate symptoms of autism spectrum disorders … htt…

Aug 6, 2024 · 2 shares · 1,081 followers View post →
seki_yo
@seki_yo · X

RT @carolynkidman: Arachidonic acid-derived dihydroxy fatty acids in neonatal cord blood relate symptoms of autism spectrum disorders … htt…

Aug 6, 2024 · 2 shares · 1,365 followers View post →
GWΞI LO
@gweilonft · X

@BioavailableNd How can you call a sample size of 200 as research? https://t.co/Bwbtzfv8Uj

Aug 6, 2024 · 1,132 followers View post →
Bruno P. Crocco
@bruno_crocco · X

RT @DiljanMansoor: https://t.co/C7lsDygF3S Japanese Scientists discovered a significant connection between increase in PUFA fatty acids in…

Aug 6, 2024 · 5 shares · 1,536 followers View post →
黒崎未知子
@carolynkidman · X

Arachidonic acid-derived dihydroxy fatty acids in neonatal cord blood relate symptoms of autism spectrum disorders … https://t.co/lNzjvoEmm2 新生児臍帯血中のアラキドン酸由来ジヒドロキシ脂肪酸は自閉症スペクトラム障害の症状と社会適応機能に関連づける:浜松母子出生コホート(HBC研究)

Aug 6, 2024 · 1 like · 2 shares · 2,966 followers View post →
seal_2020
@seal_2020 · X

RT @BioavailableNd: Research Link: https://t.co/8jMJhBMjrQ

Aug 6, 2024 · 45 shares · 457 followers View post →
Onphel
@onphel · X

@robertlufkinmd Seed oils rich in PUFA linked to autism. https://t.co/69SixJUeBq

Aug 6, 2024 · 1 like · 68 followers View post →
Pavan
@Pavanstweetz · X

RT @DiljanMansoor: https://t.co/C7lsDygF3S Japanese Scientists discovered a significant connection between increase in PUFA fatty acids in…

Aug 6, 2024 · 5 shares · 1,211 followers View post →
Awakened Princess
@GastricpH · X

RT @DiljanMansoor: https://t.co/C7lsDygF3S Japanese Scientists discovered a significant connection between increase in PUFA fatty acids in…

Aug 6, 2024 · 5 shares · 1,014 followers View post →
David Diamond
@LDLSkeptic · X

RT @DiljanMansoor: https://t.co/C7lsDygF3S Japanese Scientists discovered a significant connection between increase in PUFA fatty acids in…

Aug 6, 2024 · 5 shares · 44,758 followers View post →
Airborne
@debrief87 · X

@GrandSolarMini @BioavailableNd https://t.co/HpCkbTJt5o

Aug 6, 2024 · 26 followers View post →
Ted Clark
@tedrsa · X

RT @BioavailableNd: Research Link: https://t.co/8jMJhBMjrQ

Aug 6, 2024 · 45 shares · 182 followers View post →
Diljan Mansoor MD
@DiljanMansoor · X

https://t.co/C7lsDygF3S Japanese Scientists discovered a significant connection between increase in PUFA fatty acids in umbilical cord blood and severity autism symptoms in children. @LDLSkeptic @FructoseNo @lowcarbGP @drjasonfung

Aug 6, 2024 · 20 likes · 5 shares · 4,320 followers View post →
Sayed Tahir
@drsayedtahir · X

RT @BioavailableNd: Research Link: https://t.co/8jMJhBMjrQ

Aug 6, 2024 · 45 shares · 2,178 followers View post →
Meltdown Observer
@Constantin22409 · X

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Aug 6, 2024 · 45 shares · 342 followers View post →
OhSoDull
@OhSoDullHQ · X

@marksandspencer SEED OILS STUDY! Are you killing your customers? https://t.co/Zr3Ma94zbI

Aug 6, 2024 · 1 like · 1 share · 536 followers View post →
6のタマ
@6oftama · X

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Aug 5, 2024 · 57 followers View post →
kt
@ktgrigri · X

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Silvia de Dios
@SilviadeDios12 · X

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Enrique Manzulli
@e_manfitnesss · X

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Monique Tran
@MoniqueTran04 · X

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Jacuzzi Frog - In the Soup!
@Typ0negative · X

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TBennett
@be46990499 · X

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Matthew B
@Wontevertweet27 · X

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Terri Lewis
@terriblewis1 · X

RT @BioavailableNd: Research Link: https://t.co/8jMJhBMjrQ

Aug 5, 2024 · 45 shares · 3,009 followers View post →
Ask
@SensorySnout · X

New study reveals a link between high levels of arachidonic acid-derived fatty acids in neonatal cord blood and increased severity of ASD symptoms. Highlights the role of lipid metabolism in neurodevelopment. #ASD #Research #Neurodevelopment #PUFA https://t.co/iuJoWrtZGg

Aug 5, 2024 · 7 followers View post →
Prenatal Ease
@PrenatalEase · X

New study highlights how high levels of certain omega-6 fatty acids in neonatal cord blood are linked to increased ASD symptoms. This underscores the importance of balancing omega-6 with omega-3, especially during pregnancy. #Omega3 #prenatalease https://t.co/UlMf4YSolI

Aug 5, 2024 · 573 followers View post →
B Fisher
@NearlyPlumb · X

RT @BioavailableNd: Research Link: https://t.co/8jMJhBMjrQ

Aug 5, 2024 · 45 shares · 213 followers View post →
klamka
@pustaera · X

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Aug 5, 2024 · 45 shares · 536 followers View post →
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@IlchevLazar · X

RT @BioavailableNd: Research Link: https://t.co/8jMJhBMjrQ

Aug 5, 2024 · 45 shares · 751 followers View post →
Me
@TheM1chelinMan · X

RT @BioavailableNd: Research Link: https://t.co/8jMJhBMjrQ

Aug 5, 2024 · 45 shares · 351 followers View post →
Kelly A. Hogan Ph.D.
@Loose_Lab_Rat · X

Arachidonic acid-derived dihydroxy fatty acids in neonatal cord blood relate symptoms of autism spectrum disorders and social adaptive functioning: Hamamatsu Birth Cohort for Mothers and Children https://t.co/lELPXgFO2R

Aug 5, 2024 · 1 like · 2,240 followers View post →
Alienincologne
@alienincologne · X

RT @BioavailableNd: Research Link: https://t.co/8jMJhBMjrQ

Aug 5, 2024 · 45 shares · 185 followers View post →
Follower of the Goddess, Sophia
@GrandSolarMini · X

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@KeepOnesHopesUp · X

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Dr. Jessie Keener
@DrJessieKeener · X

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dkhd
@reryan2020 · X

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Fish Lips
@Fish_Lips_ · X

Yup, seed oils again sce: https://t.co/f1TaOQt4a4 https://t.co/a7fezcdIVh

Aug 5, 2024 · 1,388 followers View post →
Ana Pravda
@pravda_ana · X

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girlgoyle; gay
@recovereap · X

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NXT
@pratik_mahendra · X

I thought I repost one of the research paper that links autism to rally acid found in seed oil. https://t.co/qC6H6hIPqp https://t.co/903VKNQ35a

Aug 5, 2024 · 90 followers View post →
End The Evil Now
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@Psychopathicra3 · X

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@argosaki · X

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@knotme14 · X

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Debbie @ Genetic Lifehacks
@GeneticLifehack · X

Arachidonic acid-derived dihydroxy fatty acids in neonatal cord blood relate symptoms of autism spectrum disorders and social adaptive functioning: Hamamatsu Birth Cohort for Mothers and Children (HBC Study) - PubMed https://t.co/T6agvc6hED

Aug 4, 2024 · 1 like · 1,528 followers View post →
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@Bethelight99585 · X

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kippa777
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@MDoc1234567 · X

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Andra
@BioavailableNd · X

Research Link: https://t.co/8jMJhBMjrQ

Aug 4, 2024 · 209 likes · 45 shares · 139,285 followers View post →
klemps
@fullnrgy · X

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Aug 4, 2024 · 336 followers View post →
F.Yusufzai
@obsurfer84 · X

RT @agingdoc1: Arachidonic acid-derived dihydroxy fatty acids in neonatal cord blood relate symptoms of autism spectrum disorders and socia…

Aug 3, 2024 · 1 share · 295 followers View post →
Agingdoc
@agingdoc1 · X

Arachidonic acid-derived dihydroxy fatty acids in neonatal cord blood relate symptoms of autism spectrum disorders and social adaptive functioning: Hamamatsu Birth Cohort for Mothers and Children (HBC Study) https://t.co/WDXXXPJRCK https://t.co/i9LujVzikO

Aug 3, 2024 · 3 likes · 1 share · 41,683 followers View post →
Sama Hoole
@SamaHoole · X

Sauce - https://t.co/038hKwGMBf

Aug 1, 2024 · 1 like · 28,063 followers View post →
Florian
@loflude · X

@bioenergy_space Source: https://t.co/sLb2iwBR4U

Aug 1, 2024 · 1 like · 156 followers View post →
dheurtevent
@dheurtevent1 · X

Arachidonic acid-derived dihydroxy fatty acids in neonatal cord blood relate symptoms of #autism spectrum disorders and social adaptive functioning: Hamamatsu Birth Cohort for Mothers and Children (HBC Study) https://t.co/5hIjcoQ6MZ

Aug 1, 2024 · 224 followers View post →
exfatloss
@exfatloss · X

Seed oils cause autism lol https://t.co/WOqVff5xhT

Jul 31, 2024 · 10 likes · 6,674 followers View post →
Ilias Partsenidis
@IPartsenidis · X

Very interesting study looking into the pathophysiology of autism spectrum disorder. https://t.co/7O2ifCRKvy

Jul 31, 2024 · 4 likes · 52 followers View post →
Dr Imran Sheikh
@DrImranSheikh · X

Arachidonic acid-derived dihydroxy fatty acids in neonatal cord blood relate symptoms of autism spectrum disorders and social adaptive functioning: Hamamatsu Birth Cohort for Mothers and Children (HBC Study) https://t.co/UsnVkSsorR https://t.co/Qt2mRkNj7O

Jul 30, 2024 · 1 like · 24,203 followers View post →
Richard S
@Richard01173388 · X

RT @NeuroscienceNew: “Arachidonic acid-derived dihydroxy fatty acids in neonatal cord blood relate symptoms of autism spectrum disorders an…

Jul 30, 2024 · 2 shares · 155 followers View post →
Richard Smith
@Richard79215390 · X

RT @NeuroscienceNew: “Arachidonic acid-derived dihydroxy fatty acids in neonatal cord blood relate symptoms of autism spectrum disorders an…

Jul 29, 2024 · 2 shares · 228 followers View post →
Disabled World (DW)
@DisabledWorld · X

@leovdd https://t.co/ndzkMe7Eaf

Jul 29, 2024 · 42,640 followers View post →
Neuroscience News
@NeuroscienceNew · X

“Arachidonic acid-derived dihydroxy fatty acids in neonatal cord blood relate symptoms of autism spectrum disorders and social adaptive functioning: Hamamatsu Birth Cohort for Mothers and Children (HBC Study)” by Hideo Matsuzaki et al. Psychiatry and Clinical Neurosciences

Jul 29, 2024 · 5 likes · 2 shares · 505,522 followers View post →
University of Fukui
@UnivFukui_offl · X

Professor Hideo Matsuzaki and Dr. Takaharu Hirai from the University of Fukui was published online in Psychiatry and Clinical Neurosciences. https://t.co/lR8QmCg5R7

Jul 24, 2024 · 27 followers View post →