Magn Reson Med December 2024 PMID 39044608

Acute nicotinamide riboside supplementation increases human cerebral NAD levels in vivo.

Ravi Prakash Reddy Nanga, Corinde E Wiers, Mark A Elliott, Neil E Wilson, Fang Liu, Quy Cao, Sophie Swago, Paul S Jacobs, Ryan Armbruster, Damodara Reddy, Joseph A Baur, Walter R Witschey, John A Detre, Ravinder Reddy

Mentions

33
Peak: 18 in Jul 2024
across 3 sources since Jul 2024

Extended reach

162,690
potential audience

Total likes

294

Video views

6,546

Mentions per month

Jul 2024 – Dec 2025

Where it's discussed

  • X / Twitter27 posts
  • News4 articles
  • YouTube2 videos

AI synopsis

What people are saying

The discussions mostly support the article's findings, referencing technical aspects like 7T MRI scans and NAD measurement methods, which demonstrate deep interest and engagement. Words like 'promising' and 'confirm' reflect enthusiasm, but the overall tone suggests recognition of preliminary potential rather than definitive impact yet.

AgreementModerate agreement

Most discussions express support or positive anticipation regarding the findings, suggesting general agreement with the article's conclusions.

InterestHigh interest

The posts show high engagement and curiosity, frequently mentioning specific details like MRI techniques and NAD level increases.

EngagementModerate engagement

Users actively cite technical methods, implications, and potential benefits, indicating meaningful engagement.

ImpactModerate impact

Although preliminary, there's recognition that the research could influence future studies on brain health and supplements.

Abstract in brief

  • The study investigated how a single dose of nicotinamide riboside (900mg) affects NAD levels in the human brain using a specialized MRI technique, finding that NAD levels increased significantly 4 hours after ingestion.
  • Researchers performed multiple scans on 10 healthy volunteers to compare NAD levels before and after taking NR and confirmed that the increase was due to the supplement rather than variability in measurements.
  • The results suggest that acute NR supplementation can boost brain NAD levels, highlighting the potential of this method (DF H MRS) to reliably measure NAD in humans in vivo for future research.

Top posts

Most liked on X and Bluesky
Agingdoc
@agingdoc1 · X

Acute nicotinamide riboside supplementation increases human cerebral NAD+ levels in vivo

Jul 24, 2024 · 47 likes · 11 shares · 43,179 followers View post →
RaisingNAD.com
@RaisingNad · X

NEW: Acute nicotinamide riboside supplementation increases human cerebral NAD+ levels in vivo https://t.co/uA9OJ4qyYH "These preliminary results confirm that acute NR supplementation increases cerebral NAD+ levels in healthy human volunteers and shows the promise of...

Jul 24, 2024 · 13 likes · 5 shares · 1,064 followers View post →
thmonk
@thmonk_pf · X

健常人のnicotinamide riboside(NR)服用が脳内NAD+ levelへの影響を7T 1H MRSで評価 NR摂取4hr後にNAD+濃度が有意に上昇し、NRがヒト脳内NAD+ levelを高める有望な食品である可能性 低磁場側がproton交換が激しいので水抑制の無いsequenceを使用 OA #MRS #NAD #papers https://t.co/FBOvp5N2B8 https://t.co/ttyQLChKZn

Oct 1, 2024 · 4 likes · 1 share · 1,653 followers View post →
thmonk
@thmonk_pf · X

Nicotinamide Riboside(NMN)900mg経口投与4時間後の脳内NAD+増加を7T MRIを用いたMRSにて確認 NMN補給は加齢や神経疾患関連の脳内NAD+低下を改善する治療戦略となり得る NAD+ peakは水交換基なのでSequenceは狭帯域励起でSNOB refocus、水照射は無し OA #NAD #MRS #papers https://t.co/FBOvp5MuLA https://t.co/xmeq7mrp1k

Jul 31, 2024 · 3 likes · 2 shares · 1,653 followers View post →
Kelly A. Hogan Ph.D.
@Loose_Lab_Rat · X

Acute nicotinamide riboside supplementation increases human cerebral NAD+ levels in vivo https://t.co/GuBYfMpWfr

Jul 24, 2024 · 2 likes · 2,238 followers View post →
Charles Brenner, PhD
@CharlesMBrenner · X

RT @RaisingNad: NEW: Acute nicotinamide riboside supplementation increases human cerebral NAD+ levels in vivo https://t.co/uA9OJ4qyYH "Thes…

Jul 24, 2024 · 5 shares · 57,230 followers View post →

All mentions

luis hernan graffe
@hernangraffe · X

https://t.co/wUjHGIk5WJ

Aug 4, 2025 · 3,139 followers View post →
thmonk
@thmonk_pf · X

RT @thmonk_pf: 健常人のnicotinamide riboside(NR)服用が脳内NAD+ levelへの影響を7T 1H MRSで評価 NR摂取4hr後にNAD+濃度が有意に上昇し、NRがヒト脳内NAD+ levelを高める有望な食品である可能性 低磁場側…

Oct 6, 2024 · 1 share · 1,653 followers View post →
thmonk
@thmonk_pf · X

健常人のnicotinamide riboside(NR)服用が脳内NAD+ levelへの影響を7T 1H MRSで評価 NR摂取4hr後にNAD+濃度が有意に上昇し、NRがヒト脳内NAD+ levelを高める有望な食品である可能性 低磁場側がproton交換が激しいので水抑制の無いsequenceを使用 OA #MRS #NAD #papers https://t.co/FBOvp5N2B8 https://t.co/ttyQLChKZn

Oct 1, 2024 · 4 likes · 1 share · 1,653 followers View post →
Kelly A. Hogan Ph.D.
@Loose_Lab_Rat · X

Acute nicotinamide riboside supplementation increases human cerebral NAD+ levels in vivo https://t.co/GuBYfMpWfr

Sep 27, 2024 · 2,238 followers View post →
in2caffeine
@in2caffeine · X

Acute nicotinamide riboside supplementation increases human cerebral NAD+ levels in vivo - Nanga - Magnetic Resonance in Medicine - Wiley Online Library https://t.co/FrEMo5jcIx

Aug 17, 2024 View post →
Integrative Psychiatry Oklahoma
@Intpsychok · X

RT @agingdoc1: Acute nicotinamide riboside supplementation increases human cerebral NAD+ levels in vivo

Aug 12, 2024 · 11 shares · 153 followers View post →
Bill Walker
@BWalkerTTAGGG · X

RT @RaisingNad: NEW: Acute nicotinamide riboside supplementation increases human cerebral NAD+ levels in vivo https://t.co/uA9OJ4qyYH "Thes…

Aug 7, 2024 · 5 shares · 1,427 followers View post →
Hao Yin
@HaoYin20 · X

RT @thmonk_pf: Nicotinamide Riboside(NMN)900mg経口投与4時間後の脳内NAD+増加を7T MRIを用いたMRSにて確認 NMN補給は加齢や神経疾患関連の脳内NAD+低下を改善する治療戦略となり得る NAD+ peakは水交換基なの…

Aug 2, 2024 · 2 shares · 12,558 followers View post →
thmonk
@thmonk_pf · X

RT @thmonk_pf: Nicotinamide Riboside(NMN)900mg経口投与4時間後の脳内NAD+増加を7T MRIを用いたMRSにて確認 NMN補給は加齢や神経疾患関連の脳内NAD+低下を改善する治療戦略となり得る NAD+ peakは水交換基なの…

Aug 2, 2024 · 2 shares · 1,653 followers View post →
ysaito
@ysaito8015 · X

RT @thmonk_pf: Nicotinamide Riboside(NMN)900mg経口投与4時間後の脳内NAD+増加を7T MRIを用いたMRSにて確認 NMN補給は加齢や神経疾患関連の脳内NAD+低下を改善する治療戦略となり得る NAD+ peakは水交換基なの…

Jul 31, 2024 · 2 shares · 2,824 followers View post →
thmonk
@thmonk_pf · X

Nicotinamide Riboside(NMN)900mg経口投与4時間後の脳内NAD+増加を7T MRIを用いたMRSにて確認 NMN補給は加齢や神経疾患関連の脳内NAD+低下を改善する治療戦略となり得る NAD+ peakは水交換基なのでSequenceは狭帯域励起でSNOB refocus、水照射は無し OA #NAD #MRS #papers https://t.co/FBOvp5MuLA https://t.co/xmeq7mrp1k

Jul 31, 2024 · 3 likes · 2 shares · 1,653 followers View post →
Mind Your Science!
@MindYourSci · X

RT @agingdoc1: Acute nicotinamide riboside supplementation increases human cerebral NAD+ levels in vivo

Jul 29, 2024 · 11 shares · 131 followers View post →
Well Done
@welldone00 · X

RT @agingdoc1: Acute nicotinamide riboside supplementation increases human cerebral NAD+ levels in vivo

Jul 25, 2024 · 11 shares · 1,075 followers View post →
Simon Manning
@_Simon_K · X

RT @RaisingNad: NEW: Acute nicotinamide riboside supplementation increases human cerebral NAD+ levels in vivo https://t.co/uA9OJ4qyYH "Thes…

Jul 24, 2024 · 5 shares · 1,800 followers View post →
Alexander Dakhovnik
@ADakhovnik · X

RT @agingdoc1: Acute nicotinamide riboside supplementation increases human cerebral NAD+ levels in vivo

Jul 24, 2024 · 11 shares · 78 followers View post →
Charles Jourdan Reyes, Ph.D.
@reyes_jourdan · X

RT @agingdoc1: Acute nicotinamide riboside supplementation increases human cerebral NAD+ levels in vivo

Jul 24, 2024 · 11 shares · 626 followers View post →
Rafael Téllez
@rafaeltellez · X

RT @RaisingNad: NEW: Acute nicotinamide riboside supplementation increases human cerebral NAD+ levels in vivo https://t.co/uA9OJ4qyYH "Thes…

Jul 24, 2024 · 5 shares · 877 followers View post →
missfearleslie
@missfearleslie · X

RT @agingdoc1: Acute nicotinamide riboside supplementation increases human cerebral NAD+ levels in vivo

Jul 24, 2024 · 11 shares · 9,394 followers View post →
JR
@JR78202114 · X

RT @agingdoc1: Acute nicotinamide riboside supplementation increases human cerebral NAD+ levels in vivo

Jul 24, 2024 · 11 shares · 511 followers View post →
P123
@P1231032850 · X

RT @agingdoc1: Acute nicotinamide riboside supplementation increases human cerebral NAD+ levels in vivo

Jul 24, 2024 · 11 shares · 3,422 followers View post →
klamka
@pustaera · X

RT @RaisingNad: NEW: Acute nicotinamide riboside supplementation increases human cerebral NAD+ levels in vivo https://t.co/uA9OJ4qyYH "Thes…

Jul 24, 2024 · 5 shares · 517 followers View post →
Charles Brenner, PhD
@CharlesMBrenner · X

RT @RaisingNad: NEW: Acute nicotinamide riboside supplementation increases human cerebral NAD+ levels in vivo https://t.co/uA9OJ4qyYH "Thes…

Jul 24, 2024 · 5 shares · 57,230 followers View post →
John Greene
@Greene_Thoughts · X

RT @agingdoc1: Acute nicotinamide riboside supplementation increases human cerebral NAD+ levels in vivo

Jul 24, 2024 · 11 shares · 1,712 followers View post →
RaisingNAD.com
@RaisingNad · X

NEW: Acute nicotinamide riboside supplementation increases human cerebral NAD+ levels in vivo https://t.co/uA9OJ4qyYH "These preliminary results confirm that acute NR supplementation increases cerebral NAD+ levels in healthy human volunteers and shows the promise of...

Jul 24, 2024 · 13 likes · 5 shares · 1,064 followers View post →
Gohsuke Takama
@gohsuket · X

RT @agingdoc1: Acute nicotinamide riboside supplementation increases human cerebral NAD+ levels in vivo

Jul 24, 2024 · 11 shares · 2,978 followers View post →
Agingdoc
@agingdoc1 · X

Acute nicotinamide riboside supplementation increases human cerebral NAD+ levels in vivo

Jul 24, 2024 · 47 likes · 11 shares · 43,179 followers View post →
Kelly A. Hogan Ph.D.
@Loose_Lab_Rat · X

Acute nicotinamide riboside supplementation increases human cerebral NAD+ levels in vivo https://t.co/GuBYfMpWfr

Jul 24, 2024 · 2 likes · 2,238 followers View post →
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