Transl Psychiatry July 2024 PMID 39060246

Distinct saliva DNA methylation profiles in relation to treatment outcome in youth with posttraumatic stress disorder.

Judith B M Ensink, Peter Henneman, Andrea Venema, Jasper B Zantvoord, Rosanne Op den Kelder, Marcel M A M Mannens, Ramón J L Lindauer

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Mentions

Peak: 3 in Jul 2024

across 2 sources since Jul 2024

Extended reach

5,441

potential audience

Total likes

Video views

266

Mentions per month

Jul 2024 – Oct 2024

Where it's discussed

X / Twitter4 posts
YouTube2 videos

AI synopsis

What people are saying

The discourse revolves around the article’s exploration of saliva DNA methylation in relation to PTSD treatment outcomes, exemplified by Marissa's comment linking it to exposure therapies and questioning their necessity, which shows engagement with clinical implications. The repeated mention of the study's title indicates general recognition of the research's importance, while the tone balances curiosity and cautious skepticism, reflecting a moderate impact on perceptions of PTSD treatment strategies.

AgreementModerate agreement

Most contributions acknowledge or reference the publication’s focus on DNA methylation and PTSD, showing moderate support or neutral stance.

InterestModerate interest

Discussions display moderate curiosity, with some mentions of the research’s relevance and potential implications.

EngagementModerate engagement

Participants reference specific aspects like therapy methods and scientific details, indicating a curiosity-driven engagement.

ImpactModerate impact

The overall tone suggests that these social discussions could influence opinions on PTSD treatments or epigenetic research, though without decisive conclusions.

Abstract in brief

This study explored how DNA methylation in saliva might be connected to treatment outcomes in youth with PTSD, focusing on whether epigenetic changes could explain why some youths respond well to therapy and others do not.
Researchers found distinct methylation patterns in specific genes, such as C18orf63 and CRHR2, between treatment responders and nonresponders, with some changes in methylation related to cortisol secretion and therapy success.
The findings suggest that salivary DNA methylation could serve as a molecular marker for PTSD treatment response in youth, but further research is needed to confirm these results and better understand the underlying mechanisms.

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All mentions

The Hidden Impact of Trauma on DNA and Body Health

How sixteen minutes cost the life of a man and what it teaches us about the covert effect of trauma on your body and DNA. This video explores the biological changes caused by trauma, including DNA methylation and its…

Dr. Linda F. Williams, DSW · Oct 18, 2024 171 views

The Hidden Impact of Trauma on DNA and Brain Function

This video explores how a sixteen-minute incident can affect the body and DNA, highlighting trauma's covert effects like DNA methylation changes and anxiety symptoms. It emphasizes that successful PTSD treatment can…

Dr. Linda F. Williams, DSW · Oct 16, 2024 95 views

Elena

@Eowynth · X

Sep 8, 2024 · 1 like · 331 followers View post →

CopperKettle

@Artyom_Yekat · X

RT @bertogliolab: Distinct saliva DNA methylation profiles in relation to treatment outcome in youth with PTSD https://t.co/pteEsZkJ8h

Jul 29, 2024 · 2 shares · 378 followers View post →

Nathalia Le Hen

@NathaliaLeHen · X

RT @bertogliolab: Distinct saliva DNA methylation profiles in relation to treatment outcome in youth with PTSD https://t.co/pteEsZkJ8h

Jul 29, 2024 · 2 shares · 2,741 followers View post →

Bertoglio lab (FMC/UFSC)

@bertogliolab · X

Distinct saliva DNA methylation profiles in relation to treatment outcome in youth with PTSD https://t.co/pteEsZkJ8h

Jul 29, 2024 · 8 likes · 2 shares · 1,714 followers View post →