September 2024 PMID 39117878

Proteomic aging clock predicts mortality and risk of common age-related diseases in diverse populations.

M Austin Argentieri, Sihao Xiao, Derrick Bennett, Laura Winchester, Alejo J Nevado-Holgado, Upamanyu Ghose, Ashwag Albukhari, Pang Yao, Mohsen Mazidi, Jun Lv, Iona Millwood, Hannah Fry, Rodosthenis S Rodosthenous, Jukka Partanen, Zhili Zheng

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Mentions

Peak: 13 in Aug 2024

across 7 sources since Sep 2023

Extended reach

117,680

potential audience

Total likes

277

Video views

6,864

Mentions per month

Sep 2023 – Aug 2025

Where it's discussed

News38 articles
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AI synopsis

What people are saying

The discussions highlight the importance of the proteomic aging clock in health prediction, with mentions of its application across diverse populations and its potential to transform understanding of aging and mortality, as exemplified by phrases like 'predicts mortality' and 'risk of age-related diseases.' The tone emphasizes curiosity and the significance of the study, while some participants note their limitations in critiquing the research but recognize its importance.

AgreementModerate agreement

Most discussions acknowledge the significance of the proteomic aging clock in predicting health risks, reflecting general support for the study's findings.

InterestHigh interest

The discussions show high curiosity about the biological and health implications, with many referencing the potential of this research for understanding aging and mortality.

EngagementModerate engagement

Participants reference specific aspects like long-term biobank data and biological markers, indicating moderate engagement with the details of the study.

ImpactModerate impact

There is an overall perception that this research may influence future health assessments and research directions, suggesting noticeable impact.

Abstract in brief

Circulating plasma proteins are crucial for human health and can help measure biological age, which may predict risks for age-related diseases and overall mortality.
A study using data from the UK Biobank identified 204 proteins that accurately predict chronological age and are linked to 18 chronic diseases, as well as various health measures such as cognitive function and frailty.
The findings were validated in studies from China and Finland, showing that this proteomic age clock can reliably assess age-related health risks across different populations.

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All mentions

Understanding the Proteomic Aging Clock and Its Health Implications

Circulating plasma proteins are crucial for human health and can help measure biological age, which may predict risks for age-related diseases and overall mortality. This study used data from the UK Biobank to identify…

The Sheekey Science Show · Aug 24, 2024 5,519 views

Biological Age Measurement Using DNA Methylation and Proteomic Clocks

Measuring time in molecules with Dr. Laurena Law. This video discusses DNA methylation and proteomic clocks that assess biological age as biomarkers for longevity interventions, health risks, and age-related diseases…

Dr. Laurena Law · Jun 11, 2025 1,346 views

Clinical Chemistry

@Clin_Chem_ADLM · X

New Clinical Chemistry podcast: Proteomic aging clock predicts mortality and risk of common age-related diseases https://t.co/dlaI18JjQc

Aug 19, 2025 · 11,610 followers View post →

Agingdoc

@agingdoc1 · X

Is aging linear or non-linear? @SheekeyScience https://t.co/dFaMNTsUMI https://t.co/Q32J1Y5E2t

Sep 5, 2024 · 2 likes · 40,964 followers View post →

Koshi Kinoshita

@bruinwhitered · X

RT @Pon_yurublog: 血漿のプロテオーム解析によって年齢、慢性疾患などを推定するモデルを作ったというNature Medの論文プロテオーム年齢は実際の年齢とかなり高い相関を示し、加齢に関わる疾患や死亡リスクを推定するために重要な因子のようです https://…

Aug 23, 2024 · 3 shares · 74 followers View post →

機械の中の機械 2号

@S_Machine_2 · X

Aug 22, 2024 · 3 shares · 81 followers View post →

もやっしー

@moyasshi15 · X

Aug 22, 2024 · 3 shares · 323 followers View post →

Pon｜食と健康

@PonNutr · X

Aug 22, 2024 · 11 likes · 3 shares · 2,626 followers View post →

CRISP_SCIENCE

@ScienceCrisp · X

"Proteomic aging clock predicts mortality and risk of common age-related diseases in diverse populations" Argentieri MA [..] van Duijn CM. Nat Med. 2024-08-08. https://t.co/56DKl1ip6i

Aug 18, 2024 · 1,917 followers View post →

Elliot Tapper

@ebtapper · X

Aug 18, 2024 · 6 likes · 41,899 followers View post →

PubMed Trending

@PubTrend · X

Trending on PubMed: Proteomic aging clock predicts mortality and risk of common age-related diseases in diverse populations. https://t.co/c7IZ2or6j6

Aug 17, 2024 · 5,160 followers View post →

Reiner

@erlangen.bsky.social · Bluesky

Was das Blut über die Lebenserwartung verrät www.welt.de/wissenschaft... Proteomic aging clock predicts mortality and risk of common age-related diseases in diverse populations www.nature.com/articles/s41... Biological age: risk prediction for age-related diseases, multimorbidity, mortality

Aug 16, 2024 View post →

FRCBSresearch

@frcbsresearch · X

@JukkaPartanen1 @Veripalvelu participating in large collaboration work "#Proteomic #aging_clock predicts #mortality and risk of common #age_related #diseases in diverse populations". https://t.co/1yuWFQWxCi #bloodserviceresearch #biobank #Olink_Explore @OlinkProteomics

Aug 15, 2024 · 146 followers View post →

BYTESEU

@byteseu.bsky.social · Bluesky

Proteomic aging clock predicts mortality and risk of common age-related diseases in diverse populations (2024) https://www.byteseu.com/327662/ Proteomic aging clock predicts mortality and risk of common age-related diseases in diverse populations (2024) …

Aug 10, 2024 View post →

Alessandro Riolo

@aledeniz · X

Aug 10, 2024 · 1 like · 3,751 followers View post →

Kelly A. Hogan Ph.D.

@Loose_Lab_Rat · X

Proteomic aging clock predicts mortality and risk of common age-related diseases in diverse populations https://t.co/tl7QeI48YM

Aug 9, 2024 · 1 like · 2,242 followers View post →

medRxivpreprint

@medrxivpreprint.bsky.social · Bluesky

Proteomic aging clock predicts mortality and risk of common age-related diseases in diverse populations https://www.medrxiv.org/content/10.1101/2023.09.13.23295486v1

Sep 13, 2023 View post →