Am J Physiol Heart Circ Physiol October 2024 PMID 39150392

Constipation is associated with an increased risk of major adverse cardiac events in a UK population.

Tenghao Zheng, Leticia Camargo Tavares, Mauro D'Amato, Francine Z Marques

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Mentions

197
Peak: 48 in Aug 2024
across 5 sources since Jan 2024

Extended reach

307,567
potential audience

Total likes

185

Video views

8

Mentions per month

Jan 2024 – May 2025

Where it's discussed

  • News118 articles
  • X / Twitter67 posts
  • Blogs8 articles
  • YouTube2 videos
  • Facebook2 posts

AI synopsis

What people are saying

Various discussions emphasize the article's findings, with phrases such as 'constipation is a risk factor' and 'increased risk of major cardiac events' underlining the significance of the research. The tone ranges from informative to celebratory, with some posts expressing excitement over the publication's recognition in scientific circles. The language used—especially terms like 'important' and 'must consider'—reinforces the perceived urgency and relevance of the topic.

AgreementStrong agreement

The discussions generally reflect a strong consensus supporting the findings of the study, with many users expressing agreement with the link between constipation and heart risks.

InterestHigh interest

The topic sparked significant curiosity, as many posts highlight the implications of this connection, indicating a high level of engagement with the content.

EngagementHigh engagement

Posts delve into specific aspects of the research, often referencing methodologies and health implications, showcasing a deep level of interest and engagement among commentators.

ImpactHigh impact

The perception of impact is high, as numerous participants highlight the potential consequences for cardiovascular health and the importance of recognizing constipation as a risk factor.

Abstract in brief

  • Traditional cardiovascular risk factors like hypertension don’t fully explain the occurrence of major adverse cardiac events (MACEs), indicating the need to explore additional risk factors.
  • The study investigates the link between constipation and MACE using data from the UK Biobank, revealing that individuals with constipation have a significantly higher risk of developing conditions like heart failure, ischemic stroke, and acute coronary syndrome.
  • Positive genetic correlations were found between constipation and these MACE subgroups, suggesting that constipation may be an underestimated risk factor for cardiovascular diseases, prompting the need for more research into its implications and underlying mechanisms.

Top posts

Most liked on X and Bluesky
John Damianos, M.D.
@john_damianosMD · X

#Constipation is associated with a higher risk of cardiovascular disease #MedTwitter #GITwitter #motility https://t.co/IywgYFzaSZ

Aug 17, 2024 · 36 likes · 10 shares · 24,003 followers View post →
Prof Francine Marques
@FZMarques · X

Big thanks to @APSPhysiology and @merrylindseyphd for selecting our paper published in @ajpheartcirc for the APSselect

Oct 2, 2024 · 20 likes · 4 shares · 9,864 followers View post →
Prof Francine Marques
@FZMarques · X

Thanks @sarzberry for featuring our research on constipation and heart disease https://t.co/ts9EfT8QqI Original paper

Aug 25, 2024 · 20 likes · 4 shares · 9,864 followers View post →
METODOLOGICA_CL
@metodologica_cl · X

Aug 19, 2024 · 18 likes · 7 shares · 3,834 followers View post →
Prof Francine Marques
@FZMarques · X

Thanks @Carmendemigue12 for the editorial about our findings linking cardiovascular disease and constipation published in @ajpheartcirc https://t.co/oBDe5ZFgRI Original paper: https://t.co/SU2va4sPYw

Oct 17, 2024 · 15 likes · 4 shares · 9,864 followers View post →
Prof Francine Marques
@FZMarques · X

Congratulations to Dr Zheng and Dr @ctavaresleticia on the publication of our latest paper in @ajpheartcirc collab w @damato_mauro We examined whether constipation is a risk factor for cardiovascular events in the @uk_biobank https://t.co/PXvcfzCpkd

Aug 19, 2024 · 14 likes · 6 shares · 9,864 followers View post →

All mentions

Saeed Doroudiani, MSc/PhD, PEng
@SaeedDoroudiani · X

May 2, 2025 · 937 followers View post →
Sreeraj
@TechWriteCritic · X

Constipation is associated with an increased risk of major adverse cardiac events in a UK population https://t.co/AIpDhXFJhn? #health #news

Oct 29, 2024 · 163 followers View post →
Débora Simões A. Colombari
@dsac2023 · X

RT @FZMarques: Thanks @Carmendemigue12 for the editorial about our findings linking cardiovascular disease and constipation published in @a…

Oct 26, 2024 · 4 shares · 63 followers View post →
AJP-Heart and Circ
@ajpheartcirc · X

RT @FZMarques: Thanks @Carmendemigue12 for the editorial about our findings linking cardiovascular disease and constipation published in @a…

Oct 25, 2024 · 4 shares · 6,841 followers View post →
Dr Leticia Camargo Tavares
@ctavaresleticia · X

RT @FZMarques: Thanks @Carmendemigue12 for the editorial about our findings linking cardiovascular disease and constipation published in @a…

Oct 18, 2024 · 4 shares · 118 followers View post →
Carmen De Miguel, PhD, MS, FAHA
@Carmendemigue12 · X

RT @FZMarques: Thanks @Carmendemigue12 for the editorial about our findings linking cardiovascular disease and constipation published in @a…

Oct 17, 2024 · 4 shares · 3,368 followers View post →
Prof Francine Marques
@FZMarques · X

Thanks @Carmendemigue12 for the editorial about our findings linking cardiovascular disease and constipation published in @ajpheartcirc https://t.co/oBDe5ZFgRI Original paper: https://t.co/SU2va4sPYw

Oct 17, 2024 · 15 likes · 4 shares · 9,864 followers View post →
Prof Francine Marques
@FZMarques · X

Our paper is in there

Oct 7, 2024 · 12 likes · 9,864 followers View post →
AJP-Heart and Circ
@ajpheartcirc · X

RT @FZMarques: Big thanks to @APSPhysiology and @merrylindseyphd for selecting our paper published in @ajpheartcirc for the APSselect

Oct 4, 2024 · 4 shares · 6,841 followers View post →
Mauro D’Amato
@damato_mauro · X

RT @FZMarques: Big thanks to @APSPhysiology and @merrylindseyphd for selecting our paper published in @ajpheartcirc for the APSselect

Oct 3, 2024 · 4 shares · 393 followers View post →
Dr Leticia Camargo Tavares
@ctavaresleticia · X

Oh wow, our study is taking off! It has been featured by the APSselect board as one of the outstanding APS scientific papers of the month

Oct 2, 2024 · 6 likes · 118 followers View post →
Rikeish R. Muralitharan MD, PhD
@rikeishm · X

RT @FZMarques: Big thanks to @APSPhysiology and @merrylindseyphd for selecting our paper published in @ajpheartcirc for the APSselect

Oct 2, 2024 · 4 shares · 711 followers View post →
Prof Francine Marques
@FZMarques · X

Big thanks to @APSPhysiology and @merrylindseyphd for selecting our paper published in @ajpheartcirc for the APSselect

Oct 2, 2024 · 20 likes · 4 shares · 9,864 followers View post →
ラハール公式
@rahall_jp · X

RT @rahall_jp:

Sep 9, 2024 · 1 share · 207 followers View post →
ラハール公式
@rahall_jp · X

Sep 7, 2024 · 1 share · 207 followers View post →
alfred fischer
@alfredfischer17 · X

Es wurde eine Assoziation zwischen Verstopfung und schweren kardiologischen Events gefunden. #medizin #kardiologie #epidemiologie Constipation is associated with an increased risk of major adverse cardiac events in a UK population. https://t.co/RUjjOGarjp

Sep 5, 2024 · 2 likes · 363 followers View post →
Asher Mendelson, MD PhD
@AsherMendelson · X

RT @ajpheartcirc: #ArticlesInPress: Constipation is associated with an increased risk of major adverse cardiac events in a UK population Te…

Sep 4, 2024 · 3 shares · 714 followers View post →
Mauro D’Amato
@damato_mauro · X

RT @ajpheartcirc: #ArticlesInPress: Constipation is associated with an increased risk of major adverse cardiac events in a UK population Te…

Sep 4, 2024 · 3 shares · 393 followers View post →
AJP-Heart and Circ
@ajpheartcirc · X

#ArticlesInPress: Constipation is associated with an increased risk of major adverse cardiac events in a UK population Tenghao Zheng et al. https://t.co/SM8sNaX7EL @FZMarques @zhengxuhao @damato_mauro @ctavares.leticia #MACE #UKBiobank #risk #genomics https://t.co/fdiPifspai

Sep 4, 2024 · 5 likes · 3 shares · 6,841 followers View post →
Fradi Frad Dreizehn
@frad_fradi · X

Constipation is associated with an increased risk of major adverse cardiac events in a UK population | American Journal of Physiology-Heart and Circulatory Physiology https://t.co/qGz2e3i1v7

Sep 1, 2024 · 2,456 followers View post →
Bina Pattel
@BinaPattel · X

#CONSTIPATION ASSOCIATED WITH INCREASED RISK OF MAJOR ADVERSE #CARDIAC EVENTS IN UK POPULATION – NEW STUDY https://t.co/8QOnqmp8cN INCLUDING #HEART ATTACKS, #STROKES AND HEART FAILURE #CONSTIPATION – TWICE AS LIKELY TO SUFFER FROM A MAJOR #CARDIAC EVENT https://t.co/mQnZFUN9p0 https://t.co/NrMMovHsXJ

Aug 30, 2024 · 36 followers View post →
Solimut Mutuelle
@SolimutMutuelle · X

#ETUDESANTEDUSOIR La #constipation est un facteur de risque important de crises cardiaques, #AVC et insuffisance cardiaque. 1 risque qui s'accroit encore en cas d'#HTA Par @MonashUni Via @ajpheartcirc https://t.co/BZqCPpKLcW

Aug 27, 2024 · 2,653 followers View post →
Dr Leticia Camargo Tavares
@ctavaresleticia · X

RT @FZMarques: Thanks @sarzberry for featuring our research on constipation and heart disease https://t.co/ts9EfT8QqI Original paper

Aug 27, 2024 · 4 shares · 118 followers View post →
Carmen De Miguel, PhD, MS, FAHA
@Carmendemigue12 · X

RT @FZMarques: Thanks @sarzberry for featuring our research on constipation and heart disease https://t.co/ts9EfT8QqI Original paper

Aug 25, 2024 · 4 shares · 3,368 followers View post →
Monash Science
@Monash_Science · X

RT @FZMarques: Thanks @sarzberry for featuring our research on constipation and heart disease https://t.co/ts9EfT8QqI Original paper

Aug 25, 2024 · 4 shares · 5,100 followers View post →
Sarah Berry
@sarzberry · X

RT @FZMarques: Thanks @sarzberry for featuring our research on constipation and heart disease https://t.co/ts9EfT8QqI Original paper

Aug 25, 2024 · 4 shares · 2,343 followers View post →
Prof Francine Marques
@FZMarques · X

Thanks @sarzberry for featuring our research on constipation and heart disease https://t.co/ts9EfT8QqI Original paper

Aug 25, 2024 · 20 likes · 4 shares · 9,864 followers View post →
Dr Melina Georgousakis
@Melina_Gee · X

RT @FZMarques: It was a nice surprise to see someone else wrote a @ConversationEDU article about our @ajpheartcirc paper

Aug 23, 2024 · 3 shares · 4,181 followers View post →
Hany Ragy
@Hragy · X

RT @FZMarques: It was a nice surprise to see someone else wrote a @ConversationEDU article about our @ajpheartcirc paper

Aug 23, 2024 · 3 shares · 80,637 followers View post →
Prof Francine Marques
@FZMarques · X

RT @ctavaresleticia: Link to our paper: https://t.co/bK9fW8z5G1

Aug 23, 2024 · 1 share · 9,864 followers View post →
Prof Francine Marques
@FZMarques · X

It was a nice surprise to see someone else wrote a @ConversationEDU article about our @ajpheartcirc paper

Aug 23, 2024 · 6 likes · 3 shares · 9,864 followers View post →
Dr Leticia Camargo Tavares
@ctavaresleticia · X

Link to our paper: https://t.co/bK9fW8z5G1

Aug 23, 2024 · 3 likes · 1 share · 118 followers View post →
Kidney in Cardiovascular Disease
@KidneyInCVD · X

RT @FZMarques: Congratulations to Dr Zheng and Dr @ctavaresleticia on the publication of our latest paper in @ajpheartcirc collab w @damato…

Aug 21, 2024 · 6 shares · 1,920 followers View post →
Gerry Tye
@GerryTye · X

RT @FZMarques: While we cannot change some risk factors for constipation (eg being female, ageing, genetic contribution) we can change othe…

Aug 21, 2024 · 4 shares · 1,550 followers View post →
Dr Anthony Martin
@AMAinsight · X

Constipation is associated with an increased risk of major adverse cardiac events in a UK population | American Journal of Physiology-Heart and Circulatory Physiology https://t.co/TUjJztBYZ8

Aug 20, 2024 · 913 followers View post →
American Physiological Society
@APSPhysiology · X

"We identified constipation as a potential risk factor independently associated with higher [major adverse cardiac events] prevalence." Read more in @AJPHeartCirc #ArticlesInPResS: https://t.co/ObqWCyRfHl https://t.co/XQr3zZ2lr0

Aug 20, 2024 · 4 likes · 1 share · 13,987 followers View post →
Xendela
@toshihiko_KMR · X

脳卒中サバイバのゼンデラ Ⅱ: 便秘が脳梗塞リスクを2倍以上に引き上げる!遺伝的要因が示す新たな脅威 https://t.co/Uh7iQ7wPHB Constipation is associated with an increased risk of major adverse cardiac events in a UK population https://t.co/Y3RhVLmmyC

Aug 20, 2024 · 39 followers View post →
Dotcomnieuws
@dotcomnieuws · X

https://t.co/RrOkscObED https://t.co/7cbWJH3H10

Aug 20, 2024 · 2,061 followers View post →
Rikeish R. Muralitharan MD, PhD
@rikeishm · X

RT @FZMarques: Congratulations to Dr Zheng and Dr @ctavaresleticia on the publication of our latest paper in @ajpheartcirc collab w @damato…

Aug 20, 2024 · 6 shares · 711 followers View post →
Matt Dun, PhD
@MattDun17 · X

RT @FZMarques: While we cannot change some risk factors for constipation (eg being female, ageing, genetic contribution) we can change othe…

Aug 19, 2024 · 4 shares · 3,170 followers View post →
Arturo Trostel
@XxTurok · X

RT @metodologica_cl:

Aug 19, 2024 · 7 shares · 201 followers View post →
call me red
@Hpixiie · X

RT @metodologica_cl:

Aug 19, 2024 · 7 shares · 345 followers View post →
Janet
@Janet90476632 · X

RT @metodologica_cl:

Aug 19, 2024 · 7 shares · 5,865 followers View post →
Carmen De Miguel, PhD, MS, FAHA
@Carmendemigue12 · X

RT @FZMarques: While we cannot change some risk factors for constipation (eg being female, ageing, genetic contribution) we can change othe…

Aug 19, 2024 · 4 shares · 3,368 followers View post →
Mauro D’Amato
@damato_mauro · X

RT @FZMarques: Congratulations to Dr Zheng and Dr @ctavaresleticia on the publication of our latest paper in @ajpheartcirc collab w @damato…

Aug 19, 2024 · 6 shares · 393 followers View post →
Comunista libertaria | Ⓐ☭
@Anarcacomunista · X

RT @metodologica_cl:

Aug 19, 2024 · 7 shares · 416 followers View post →
Dr. Keith R. Brunt
@prof_brunt · X

RT @FZMarques: Congratulations to Dr Zheng and Dr @ctavaresleticia on the publication of our latest paper in @ajpheartcirc collab w @damato…

Aug 19, 2024 · 6 shares · 2,528 followers View post →
Seymourdiera
@PZajatt · X

RT @metodologica_cl:

Aug 19, 2024 · 7 shares · 333 followers View post →
Francisco Figueroa
@PanchoFigueroas · X

RT @metodologica_cl:

Aug 19, 2024 · 7 shares · 2,617 followers View post →
METODOLOGICA_CL
@metodologica_cl · X

Aug 19, 2024 · 18 likes · 7 shares · 3,834 followers View post →
Carmen De Miguel, PhD, MS, FAHA
@Carmendemigue12 · X

RT @FZMarques: Congratulations to Dr Zheng and Dr @ctavaresleticia on the publication of our latest paper in @ajpheartcirc collab w @damato…

Aug 19, 2024 · 6 shares · 3,368 followers View post →
Paulo Morais
@PauloMo60053925 · X

RT @FZMarques: Congratulations to Dr Zheng and Dr @ctavaresleticia on the publication of our latest paper in @ajpheartcirc collab w @damato…

Aug 19, 2024 · 6 shares · 146 followers View post →
Fernando Guimaraes
@Fer_NK_nando · X

RT @FZMarques: While we cannot change some risk factors for constipation (eg being female, ageing, genetic contribution) we can change othe…

Aug 19, 2024 · 4 shares · 2,440 followers View post →
Prof Francine Marques
@FZMarques · X

While we cannot change some risk factors for constipation (eg being female, ageing, genetic contribution) we can change other risk factors that also contribute to cardiovascular disease including increasing exercise & dietary fibre intake Our paper

Aug 19, 2024 · 11 likes · 4 shares · 9,864 followers View post →
Prof Francine Marques
@FZMarques · X

Congratulations to Dr Zheng and Dr @ctavaresleticia on the publication of our latest paper in @ajpheartcirc collab w @damato_mauro We examined whether constipation is a risk factor for cardiovascular events in the @uk_biobank https://t.co/PXvcfzCpkd

Aug 19, 2024 · 14 likes · 6 shares · 9,864 followers View post →
Nutrióloga Jessica Pérez
@nutriJesssica · X

RT @john_damianosMD: #Constipation is associated with a higher risk of cardiovascular disease #MedTwitter #GITwitter #motility https://…

Aug 18, 2024 · 10 shares · 763 followers View post →
LUIS GARCIA CARRION
@LGARCIALSM · X

RT @john_damianosMD: #Constipation is associated with a higher risk of cardiovascular disease #MedTwitter #GITwitter #motility https://…

Aug 18, 2024 · 10 shares · 489 followers View post →
System
@liyongcsco12 · X

RT @john_damianosMD: #Constipation is associated with a higher risk of cardiovascular disease #MedTwitter #GITwitter #motility https://…

Aug 18, 2024 · 10 shares · 61 followers View post →
Mayela HJ
@MAYELAHJ · X

RT @john_damianosMD: #Constipation is associated with a higher risk of cardiovascular disease #MedTwitter #GITwitter #motility https://…

Aug 18, 2024 · 10 shares · 210 followers View post →
Anant Jawahar Raina
@AJRaina01 · X

RT @john_damianosMD: #Constipation is associated with a higher risk of cardiovascular disease #MedTwitter #GITwitter #motility https://…

Aug 17, 2024 · 10 shares · 536 followers View post →
Alper Aydın (Dietitian )
@aydinnalper · X

RT @john_damianosMD: #Constipation is associated with a higher risk of cardiovascular disease #MedTwitter #GITwitter #motility https://…

Aug 17, 2024 · 10 shares · 1,427 followers View post →
Viviana
@VivianAya93 · X

RT @john_damianosMD: #Constipation is associated with a higher risk of cardiovascular disease #MedTwitter #GITwitter #motility https://…

Aug 17, 2024 · 10 shares · 134 followers View post →
richar hipolito
@richar_andres · X

RT @john_damianosMD: #Constipation is associated with a higher risk of cardiovascular disease #MedTwitter #GITwitter #motility https://…

Aug 17, 2024 · 10 shares · 406 followers View post →
Adriana B
@Adribottero · X

RT @john_damianosMD: #Constipation is associated with a higher risk of cardiovascular disease #MedTwitter #GITwitter #motility https://…

Aug 17, 2024 · 10 shares · 728 followers View post →
John Damianos, M.D.
@john_damianosMD · X

#Constipation is associated with a higher risk of cardiovascular disease #MedTwitter #GITwitter #motility https://t.co/IywgYFzaSZ

Aug 17, 2024 · 36 likes · 10 shares · 24,003 followers View post →
Kewin Siah
@KewinSiah · X

#stoolcankill: New study reveals #constipation increases risk of major adverse cardiac events by 2.15 times!

Aug 17, 2024 · 10 likes · 2,361 followers View post →
medRxiv
@medrxivpreprint · X

Constipation is associated with an increased risk of major adverse cardiac events in a UK population https://t.co/7nalpwdaSE #medRxiv

Jan 24, 2024 · 1 like · 17,457 followers View post →