Low-cost and scalable projected light-sheet microscopy for the high-resolution imaging of cleared tissue and living samples | Nature Biomedical Engineering https://t.co/dsiUVHyle6
Low-cost and scalable projected light-sheet microscopy for the high-resolution imaging of cleared tissue and living samples.
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Aug 2024 – Nov 2024Where it's discussed
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X / Twitter19 posts
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YouTube12 videos
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News3 articles
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What people are saying
This collection of discussions overwhelmingly supports the publication, with posts calling it a 'game changer' and emphasizing its role in democratizing high-resolution imaging for biomedical research. The tone is optimistic and excited, especially when mentioning applications for brain studies and live sample imaging, demonstrating both enthusiasm and a recognition of its transformative potential.
Most comments praise the development as a valuable innovation, emphasizing its affordability and versatility.
Discussions reflect high curiosity about the technology's applications, especially in biomedical research and brain imaging.
Some posts delve into technical details and potential uses, indicating active participation and deeper understanding.
Multiple posts highlight the significance of making high-resolution imaging more accessible, suggesting strong potential influence on the field.
Abstract in brief
- Light-sheet fluorescence microscopy (LSFM) is effective for imaging cleared tissue and living samples, but traditional systems are expensive and difficult to scale.
- The newly developed 'projected light-sheet microscopy' (pLSM) offers a low-cost and versatile alternative using consumer-grade components, optimized optics, and software-driven control for high-resolution imaging.
- pLSM has been successfully tested for mapping mouse brains, analyzing human brain samples, and live imaging of bacterial biofilms, making high-resolution LSFM more accessible for biomedical research.
Top posts
Most liked on X and BlueskyLow-cost and scalable projected light-sheet microscopy for the high-resolution imaging of cleared tissue and living samples (relevance: 97%) https://t.co/eTZW5KbmxW #biophotonics #biomedicaloptics
DYK research from a #NewInnovator award funded by our #NIHHighRisk Research Program enabled development of a low-cost #microscope that can image whole organs and live specimens? See how it can increase access to #3D imaging & its application to the #brain: https://t.co/6NGkDah6lO https://t.co/Fp9XPX8e1K
RT @seiriki_: Low-cost and scalable projected light-sheet microscopy for the high-resolution imaging of cleared tissue and living samples |…
RT @seiriki_: Low-cost and scalable projected light-sheet microscopy for the high-resolution imaging of cleared tissue and living samples |…
RT @seiriki_: Low-cost and scalable projected light-sheet microscopy for the high-resolution imaging of cleared tissue and living samples |…
All mentions
High-Resolution Imaging of Human Brain Tissue Using Light-Sheet Microscopy
High-resolution imaging of Alzheimer's and neurotypical human brains using scalable projected light-sheet microscopy, providing a cost-effective alternative for detailed tissue analysis and live sample imaging.
Scalable Low-Cost Light-Sheet Microscopy for Brain Imaging
Light-sheet fluorescence microscopy is effective for imaging cleared tissue and living samples, but traditional systems are expensive and difficult to scale. The new projected light-sheet microscopy (pLSM) offers a…
High-Resolution Imaging of Human Brain Vasculature Using pLSM
High-resolution rendering of vasculature at different depths in human brain samples using scalable projected light-sheet microscopy, a low-cost technique for imaging cleared tissue and living samples, enhancing access…
High-Resolution Imaging of Bacterial Biofilms at Air-Liquid Interface using pLSM
Live imaging of bacterial biofilm pellicles at the air-liquid interface using low-cost projected light-sheet microscopy, a versatile technique for high-resolution imaging of living samples and tissues, making advanced…
High-Resolution Imaging of Brain Vasculature with Projected Light-Sheet Microscopy
The video showcases multichannel pLSM imaging of vasculature in a human brain sample, highlighting a low-cost, scalable approach for high-resolution imaging of cleared tissues and living samples using consumer-grade…
High-Resolution Mouse Brain Neuron Imaging with pLSM Microscopy
This video demonstrates detailed visualization of mouse brain neurons using projected light-sheet microscopy. pLSM offers a low-cost, scalable approach for high-resolution imaging of cleared tissue and live samples…
Automatic Mapping of Mouse Brain Dopamine System Using pLSM and COLM Imaging
This video demonstrates the use of projected light-sheet microscopy for high-resolution, scalable imaging of the mouse brain's dopamine system, highlighting the method's affordability and effectiveness in…
Whole-brain visualization of a transgenic mouse using pLSM microscopy
Whole-brain rendering of CLARITY-cleared Thy1eYFP transgenic mouse brain imaged using pLSM, a low-cost scalable projected light-sheet microscopy technique for high-resolution imaging of cleared tissue and living…
Low-Cost Projected Light-Sheet Microscopy for High-Resolution Imaging
Volumetric rendering of hiPS cell-derived vessel organoids using pLSM microscopy. This technique offers a scalable, low-cost approach for high-resolution imaging of cleared tissues and live samples, enhancing biomedical…
Low-Cost Projected Light-Sheet Microscopy for Brain Imaging
Light-sheet fluorescence microscopy is effective for imaging cleared tissue and living samples, but traditional systems are expensive and difficult to scale. The newly developed pLSM offers a low-cost, versatile…
Bacterial biofilms formed at air–liquid interface | pLSM live imaging
Bacterial biofilms formed at air–liquid interface | pLSM live imaging
DYK research from a #NewInnovator award funded by our #NIHHighRisk Research Program enabled development of a low-cost #microscope that can image whole organs and live specimens? See how it can increase access to #3D imaging & its application to the #brain: https://t.co/6NGkDah6lO https://t.co/Fp9XPX8e1K
RT @seiriki_: Low-cost and scalable projected light-sheet microscopy for the high-resolution imaging of cleared tissue and living samples |…
RT @seiriki_: Low-cost and scalable projected light-sheet microscopy for the high-resolution imaging of cleared tissue and living samples |…
RT @seiriki_: Low-cost and scalable projected light-sheet microscopy for the high-resolution imaging of cleared tissue and living samples |…
RT @seiriki_: Low-cost and scalable projected light-sheet microscopy for the high-resolution imaging of cleared tissue and living samples |…
RT @seiriki_: Low-cost and scalable projected light-sheet microscopy for the high-resolution imaging of cleared tissue and living samples |…
RT @seiriki_: Low-cost and scalable projected light-sheet microscopy for the high-resolution imaging of cleared tissue and living samples |…
Low-cost and scalable projected light-sheet microscopy for the high-resolution imaging of cleared tissue and living samples | Nature Biomedical Engineering https://t.co/dsiUVHyle6
(rt) Low-cost and scalable projected light-sheet microscopy for the high-resolution imaging of cleared tissue and living samples https://t.co/eTZW5KbmxW #biophotonics #biomedicaloptics
RT @biophotonicat: Low-cost and scalable projected light-sheet microscopy for the high-resolution imaging of cleared tissue and living samp…
RT @biophotonicat: Low-cost and scalable projected light-sheet microscopy for the high-resolution imaging of cleared tissue and living samp…
RT @biophotonicat: Low-cost and scalable projected light-sheet microscopy for the high-resolution imaging of cleared tissue and living samp…
RT @biophotonicat: Low-cost and scalable projected light-sheet microscopy for the high-resolution imaging of cleared tissue and living samp…
RT @biophotonicat: Low-cost and scalable projected light-sheet microscopy for the high-resolution imaging of cleared tissue and living samp…
RT @biophotonicat: Low-cost and scalable projected light-sheet microscopy for the high-resolution imaging of cleared tissue and living samp…
RT @biophotonicat: Low-cost and scalable projected light-sheet microscopy for the high-resolution imaging of cleared tissue and living samp…
RT @biophotonicat: Low-cost and scalable projected light-sheet microscopy for the high-resolution imaging of cleared tissue and living samp…
Low-cost and scalable projected light-sheet microscopy for the high-resolution imaging of cleared tissue and living samples (relevance: 97%) https://t.co/eTZW5KbmxW #biophotonics #biomedicaloptics
Low-cost and scalable projected light-sheet microscopy for the high-resolution imaging of cleared tissue and living samples https://t.co/rWB7Q0gVol