Int J Cancer January 2025 PMID 39222307

Use of menopausal hormone therapy before and after diagnosis and ovarian cancer survival-A prospective cohort study in Australia.

Renhua Na, Susan J Jordan, Anna DeFazio, Merran Williams, Karen Livingstone, Andreas Obermair, Michael Friedlander, Peter Grant, Penelope M Webb

Mentions

3
Peak: 1 in Sep 2024
across 2 sources since Sep 2024

Extended reach

5,673
potential audience

Total likes

4

Video views

23

Mentions per month

Sep 2024 – Nov 2024

Where it's discussed

  • X / Twitter2 posts
  • YouTube1 videos

AI synopsis

What people are saying

The discussions show moderate agreement and interest, with responses emphasizing survival benefits linked to MHT and referencing specifics such as higher survival rates for women with HGSC. Phrases like 'may improve survival' and mentions of age groups reflect a focus on clinical implications, demonstrating engaged and somewhat impactful responses.

AgreementModerate agreement

Most discussions acknowledge the potential positive effects of MHT on survival, especially for HGSC, indicating a general agreement with the publication's findings.

InterestModerate interest

Posts demonstrate moderate curiosity, focusing on the survival benefits and clinical implications, though not extensively exploring broader issues.

EngagementHigh engagement

Several discussions actively interpret key points like the specific impacts on subgroups and potential treatment considerations, showing deep engagement.

ImpactModerate impact

The discussions highlight the importance of these findings for clinical decision-making and future research, but the overall influence on practice appears moderate.

Abstract in brief

  • The study found that women who used menopausal hormone therapy (MHT) before their ovarian cancer diagnosis generally had better survival rates, especially for a type called high-grade serous carcinoma (HGSC), regardless of how long or recent the use was.
  • Using MHT after ovarian cancer treatment did not seem to affect survival for women with HGSC, but those who started MHT after treatment reported lower health-related quality of life (HRQOL) both before and after beginning therapy.
  • Overall, prediagnosis MHT is linked to improved survival in ovarian cancer, particularly HGSC, but posttreatment MHT use doesn’t improve survival and may negatively impact quality of life, highlighting the need for more research on menopause-specific issues in these patients.]

Top posts

Most liked on X and Bluesky
International Journal of Cancer
@IntJCanc · X

NOW ONLINE Authors from @QIMRB_Institute suggest menopausal hormone therapy may improve survival for #OvarianCancer patients and help manage symptoms in younger women

Oct 31, 2024 · 3 likes · 1,788 followers View post →
Dr. José Luis Neyro
@doctorneyro · X

Pre-#diagnosis #MHT use was associated with improved #survival, particularly in #HGSC. Among women ≤55 years, use of MHT following #treatment was not associated with #poorersurvival for HGSC. #highgrade #serouscarcinoma https://t.co/DAAlUIqDf3 https://t.co/QVIztUdaxC

Sep 28, 2024 · 1 like · 3,863 followers View post →

All mentions

International Journal of Cancer
@IntJCanc · X

NOW ONLINE Authors from @QIMRB_Institute suggest menopausal hormone therapy may improve survival for #OvarianCancer patients and help manage symptoms in younger women

Oct 31, 2024 · 3 likes · 1,788 followers View post →
Dr. José Luis Neyro
@doctorneyro · X

Pre-#diagnosis #MHT use was associated with improved #survival, particularly in #HGSC. Among women ≤55 years, use of MHT following #treatment was not associated with #poorersurvival for HGSC. #highgrade #serouscarcinoma https://t.co/DAAlUIqDf3 https://t.co/QVIztUdaxC

Sep 28, 2024 · 1 like · 3,863 followers View post →