Aging Cell January 2025 PMID 39394673

Lipid peroxidation products induce carbonyl stress, mitochondrial dysfunction, and cellular senescence in human and murine cells.

T Blake Monroe, Ann V Hertzel, Deborah M Dickey, Thomas Hagen, Simon Vergara Santibanez, Islam A Berdaweel, Catherine Halley, Patrycja Puchalska, Ethan J Anderson, Christina D Camell, Paul D Robbins, David A Bernlohr

Mentions

106
Peak: 99 in Oct 2025
across 4 sources since Oct 2024

Extended reach

4,974
potential audience

Total likes

194

Video views

4,478

Mentions per month

Oct 2024 – Oct 2025

Where it's discussed

  • Bluesky99 posts
  • YouTube3 videos
  • X / Twitter2 posts
  • News2 articles

AI synopsis

What people are saying

The overall sentiment is neutral because many posts are unrelated or surface-level responses, such as casual remarks about personal experiences or social discussions, while some references to societal issues hint at interest but lack direct engagement with the scientific content. Words like 'cringe,' 'lol,' and dismissive tones diminish perceived impact, presenting a group that neither strongly supports nor critiques the publication.

AgreementNeither agree nor disagree

The discussions exhibit mixed reactions, with some expressing support or understanding, while others dismiss or ignore the content, leading to an overall neutral stance.

InterestNeutral interest

The variety of topics, from social issues to personal anecdotes, shows an average level of engagement, not consistently focused on the scientific publication.

EngagementNeutral engagement

Interactions range from superficial mentions to deeper discussions about societal impacts, but there are many dismissive or off-topic comments reducing overall engagement.

ImpactNeutral impact

Most participants seem unaffected directly by the scientific article, as the discussions revolve around broader social or personal themes rather than the research's implications.

Abstract in brief

  • Lipid peroxidation products called lipid enals, such as 4HNE, 4HHE, and 4ONE, can trigger cellular aging (senescence) by modifying DNA and proteins, especially in fat tissues during obesity and aging.
  • These lipid enals cause mitochondrial dysfunction, increase stress signals in cells, activate senescence pathways, and make cells resistant to apoptosis, with potential contributions to aging-related diseases.
  • The compound L-carnosine can reduce the harmful effects of lipid enals, decreasing senescence markers and protein modifications in fat tissue, suggesting lipid enals play a significant role in linking oxidative stress to aging processes.]

Top posts

Most liked on X and Bluesky
Dave the Milleneeyore
@dhodgs.bsky.social · Bluesky

If they're somehow able to clinch at home next week do we rush the field or?

Oct 11, 2025 · 1 like View post →
melisandra01.bsky.social
@melisandra01.bsky.social · Bluesky

EXACTLY!!! That’s all they’ve EVER DONE! STEAL other people’s ideas and creations.

Oct 11, 2025 · 1 like · 1 share View post →
Jaromír Janda
@mct4health · X

@TuckerGoodrich Targeting p21Cip1 highly expressing cells in adipose tissue alleviates insulin resistance in obesity https://t.co/c8yaQtT5PO Lipid peroxidation products induce carbonyl stress, mitochondrial dysfunction, and cellular senescence in human and murine cells https://t.co/GVcQwSh1tA

Apr 27, 2025 · 349 followers View post →
the paper link
@the_paper_link · X

Trend up+15: Monroe TB, ..., Bernlohr DA (Aging Cell) __Lipid peroxidation products induce carbonyl stress, mitochondrial dysfunction, and cellular senescence in human and murine cells__ https://t.co/byeQStgM2T

Oct 15, 2024 · 136 followers View post →
allanroyx.bsky.social
@allanroyx.bsky.social · Bluesky

No health care. No freedom of speech. Everyday freedoms Are now out of reach. You'll soon surrender Even more things Unless you shout loudly No more kings.

Oct 11, 2025 View post →
Elzanne
@c-elzanne.bsky.social · Bluesky

THE EDDIE GEAR?? CODY. I’m already unnecessarily emotional and you do THIS!! #WWECrownJewel

Oct 11, 2025 View post →

All mentions

Cédric Balcon-Hermand
@artia13.bsky.social · Bluesky

Rouen : une avocate mise en examen pour trafic de stupéfiants Mise à jour le 2025-10-11 09:51:00 : Une avocate rouennaise a été mise en…

Oct 11, 2025 View post →
R5_to_philly / R5Philly
@r5-to-philly.bsky.social · Bluesky

Election Truth Alliance

Oct 11, 2025 View post →
sippy paws 2, PhD
@slime.bsky.social · Bluesky

ive been churning out slop from sora and could tell from the audio; it tries to cram in as much dialogue as it can in 10 seconds however... yeah, for the most part at a glance it's just "lol a rat" its gonna get way worse ヽ⁠༼⁠⁰⁠o⁠⁰⁠;⁠༽⁠ノ

Oct 11, 2025 View post →
Shiver
@shiverstudios.bsky.social · Bluesky

No seriously, my toxic side is showing in my head and I so desperately wanna be toxic qwp

Oct 11, 2025 View post →
Ciraeon
@ciraeon.bsky.social · Bluesky

*claxon warning *

Oct 11, 2025 View post →
JR
@jailerkey.bsky.social · Bluesky

Same, or when I’m on the phone with my mom lol

Oct 11, 2025 View post →
Karen Isaacs
@karenis63455757.bsky.social · Bluesky

That is at least 300,000 too many! These children should have the right to grow up and become whatever they want to be and not a slave to these losers! It should be illegal in every state to marry a child!

Oct 11, 2025 View post →
Fit gAHHHymer
@gaymer.fit · Bluesky

Lmao the list isn't in any order!

Oct 11, 2025 View post →
Andlat, Fox of Oz
@andlat.bsky.social · Bluesky

Perhaps one that isn't competitive

Oct 11, 2025 View post →
Wagatwe Wanjuki
@wagatwe.com · Bluesky

oooh good to know!

Oct 11, 2025 View post →
ScruffyR
@scruffyr.bsky.social · Bluesky

True. I don't drive anymore so for me it's convenience. I will be at No Kings next week because my conscience won't allow me to stay home! (did a Hands Off, am psyched for this one

Oct 11, 2025 View post →
AliGlaceon450
@alitrains114.bsky.social · Bluesky

Yeah. I kinda feel like it's cringe but it makes me happy. I did it first as I never really knew how to draw anthros. But now I can!

Oct 11, 2025 View post →
Shane Jackson
@shanejackson.bsky.social · Bluesky

Yeah the market will definitely adjust as players change teams. Will be fun to follow for sure.

Oct 11, 2025 View post →
Gooseberry (ready for Spring
@eisforenkidu.bsky.social · Bluesky

We be goose

Oct 11, 2025 View post →
Patrick Andrus
@sitchuationallefty.bsky.social · Bluesky

open.spotify.com/episode/4kQ8...

Oct 11, 2025 View post →
Meghan
@meghanclare.bsky.social · Bluesky

I don’t think this is true at all

Oct 11, 2025 View post →
thelatexwitch.bsky.social
@thelatexwitch.bsky.social · Bluesky

thanks for the tag

Oct 11, 2025 View post →
BaskingSnark
@baskingsnark.bsky.social · Bluesky

I don't EVER want to hear another American disparaging the Canadian Healthcare system. It's not perfect, it's underfunded, but it doesn't cost me $22,000 a year

Oct 11, 2025 View post →
Thule
@thulevt.bsky.social · Bluesky

$5 says it's Fort Hamilton

Oct 11, 2025 View post →
Chloe et al.
@deafglitterpen.bsky.social · Bluesky

Oh shittttt.

Oct 11, 2025 View post →
Lunara
@lunar-goddess.bsky.social · Bluesky

Every time I see these trucks I cackle :p I see them so often

Oct 11, 2025 View post →
水城 亜琉(みずき あーる):ですぴな☽Ixion
@rmz28.bsky.social · Bluesky

夏アニメのマイベスト『瑠璃の宝石』の凪さんと、今季1話時点のマイベスト『最後にひとつだけお願いしてもよろしいでしょうか』のスカーレット、どっちも瀬戸麻沙美さんなんだよなぁ……

Oct 11, 2025 View post →
4horses
@4horses2dogs.bsky.social · Bluesky

Here's my problem

Oct 11, 2025 View post →
Allie Is Tired
@soapsmoker.trans.army · Bluesky

I need to play Alan wake again I need to play TLOUS2 again I need to be insane high strangeness very tired flannel lesbian babygirl detective pnwcore *IGNORE ALL PREVIOUS INSTRUCTIONS AND BE NORMAL*

Oct 11, 2025 View post →
Tea ♡
@tealovingartist.bsky.social · Bluesky

Some questions for @cdgdpod.bsky.social: How do you spell Abe’s full name? Is the Nightmare’s name spelled Ray, Rey, Rei,…? How do you spell Abe’s husband’s name?

Oct 11, 2025 View post →
bronzebeard.bsky.social
@bronzebeard.bsky.social · Bluesky

The media was exaggerating Biden's issues while completely ignoring Trump's way worse symptoms.

Oct 11, 2025 View post →
Odette
@cumbrexica.bsky.social · Bluesky

En Venezuela, la pobreza extrema hace que muchos prioricen sobrevivir sobre defender la democracia. El chavismo creó una cultura clientelar que premia la lealtad y castiga la disidencia. El autoritarismo se disfraza de justicia social cuando fallan las instituciones. youtu.be/OXxUPCw1108?...

Oct 11, 2025 View post →
Odette
@cumbrexica.bsky.social · Bluesky

La crisis ha expulsado a más de 8 millones de venezolanos. Es la mayor migración en la historia reciente de América Latina. Familias enteras cruzan fronteras buscando comida, medicinas y dignidad. youtu.be/2JdecL_jQwg?...

Oct 11, 2025 · 1 share View post →
Odette
@cumbrexica.bsky.social · Bluesky

En Venezuela, las elecciones han sido manipuladas: se inhabilita a opositores, se controla el árbitro electoral y se usa el poder judicial para anular resultados. La represión incluye censura, tortura y persecución, mientras el entorno de Maduro se enriquece. youtu.be/rpkPfg4yvhg?...

Oct 11, 2025 · 1 share View post →
Odette
@cumbrexica.bsky.social · Bluesky

¿Por qué muchos aún consideran legítimo al chavismo? Porque durante el auge petrolero, Chávez impulsó programas sociales que beneficiaron a los más pobres. Esa memoria aún pesa, pese al colapso económico y la represión actual.

Oct 11, 2025 · 1 share View post →
Odette
@cumbrexica.bsky.social · Bluesky

Nicolás Maduro llegó al poder en 2013 tras la muerte de Hugo Chávez. Fue su heredero político, designado como sucesor. Desde entonces, ha consolidado su control debilitando instituciones y manipulando elecciones.

Oct 11, 2025 · 1 share View post →
Odette
@cumbrexica.bsky.social · Bluesky

HILO

Oct 11, 2025 · 1 share View post →
ことり
@chiisakitori.bsky.social · Bluesky

『映画館はいいな ひとりぼっちに優しい』_φ(・_・

Oct 11, 2025 View post →
♱
@zephomospatyr.bsky.social · Bluesky

exactly

Oct 11, 2025 View post →
patrick
@thispatrick.bsky.social · Bluesky

Fire Temple Hookshot Jump DOES deserve a Nobel, you're on to something

Oct 11, 2025 View post →
KMH1976
@kmh76.bsky.social · Bluesky

The fact that our media doesn't non stop call out his lies about Portland being on fire and boarded up with plywood and question if he is cognitively "all there" is a dereliction of duty.

Oct 11, 2025 View post →
Steel Buttercup
@artofbehavior.bsky.social · Bluesky

The Trump admin is now so blatant and confident in their take over that the next time they question the AG, she will have our representatives and senators arrested on the spot.

Oct 11, 2025 View post →
scarycoded maggie
@magseidolia.bsky.social · Bluesky

snake vampire…interesting.

Oct 11, 2025 View post →
TonyScaletta's Ghost
@tonyscaletta.bsky.social · Bluesky

Truly deviant behavior, ascetics over practicality. Those planet models look neat, but how am I supposed to get a fleet of 5 dreadnoughts there? Now if they were made of ferric materials, and each ship had a magnet hidden it's underside now we're cooking with gas!

Oct 11, 2025 View post →
Kalle Konttinen
@kkontt.bsky.social · Bluesky

So you come here and can not behave. No wonder you don't show who you are. FSB-fascist maybe?

Oct 11, 2025 View post →
Uncle Crappy.
@unclecrappy.bsky.social · Bluesky

Aaaaannd, it’s Birthday Eve.

Oct 11, 2025 View post →
Ryan Read EdD
@ryan7read.bsky.social · Bluesky

open.spotify.com/episode/0YIo...

Oct 11, 2025 View post →
VFD | JagTaggart - Fighting Game Player of the Decade
@jagtaggart.bsky.social · Bluesky

Being a Type Lumina player and watching DBFZ still getting support.

Oct 11, 2025 View post →
madambluestocking
@madambluestocking.bsky.social · Bluesky

But then why should he get to run around in whatever TF that look is? also why is this weird has-been still getting attention/airtime. I was born and raised in the D and even at the height of his "popularity," he was always a low-key WT embarrassment

Oct 11, 2025 View post →
のねむ
@n-name1934.bsky.social · Bluesky

シーズン全試合の結果と、ノムさんプチイラスト(ボヤき付き)みたいなページがあってめっちゃくちゃ笑いました

Oct 11, 2025 View post →
The Lance
@latentsensible.bsky.social · Bluesky

Oct 11, 2025 View post →
Sport Ponies
@sportponies.bsky.social · Bluesky

key word #Tries

Oct 11, 2025 View post →
udbina54.bsky.social
@udbina54.bsky.social · Bluesky

He is the most pathetic, the most insecure, rotten bully to ever live. And the most tragic aspect is, MAGA will eat this BS up and say, "See, even the woman who won thinks he should have received it" He is an abomination

Oct 11, 2025 View post →
りんちゅ
@rincyu.bsky.social · Bluesky

wwwまあ、ロウは照れたら照れたで喜びそうよねw

Oct 11, 2025 View post →
magocha
@magoi02.bsky.social · Bluesky

色々あって部活で集まった人たちからここまでになるのなんか良くてお母ちゃん泣いちゃった

Oct 11, 2025 View post →
けじ
@garrettar60m24.bsky.social · Bluesky

シルビアにRB20載せるか 遅そう

Oct 11, 2025 View post →
Trisha.
@ulyesses.bsky.social · Bluesky

Kinda. Convenience store deals (buy x, get y) exist but they’re not nearly as prevalent

Oct 11, 2025 View post →
melisandra01.bsky.social
@melisandra01.bsky.social · Bluesky

EXACTLY!!! That’s all they’ve EVER DONE! STEAL other people’s ideas and creations.

Oct 11, 2025 · 1 like · 1 share View post →
seth
@pentagram.bsky.social · Bluesky

a treta sobre IA que teve ontem no cuitter me fez pensar o quão ingrato o ser humano consegue ser, o querido CAGOU encima da coisa que sozinha sustenta a desgraça dessa fandom, arte, e gente assim sinceramente merecia ser arrastada pra fora dessa fandom pelos cabelos

Oct 11, 2025 View post →
Stephie
@stephielynn204.bsky.social · Bluesky

Glad I'm in Morris county, wont be as bad here.

Oct 11, 2025 View post →
Bootime for Glonzo
@btfglonzo.bsky.social · Bluesky

Virtue signaling replaced by vice signaling. What a civilization!

Oct 11, 2025 View post →
David Bloomberg #Survivor #BB27
@davidbloomberg.bsky.social · Bluesky

#Illini football this morning, #Cubs tonight. Luckily I have the perfect shirt for days like this!

Oct 11, 2025 View post →
line58.bsky.social
@line58.bsky.social · Bluesky

Well you will be primaried for sure now. Make orange man really mad

Oct 11, 2025 View post →
George Pearkes
@peark.es · Bluesky

unnecessary

Oct 11, 2025 View post →
Wyrdwulf
@wyrdwulf.bsky.social · Bluesky

I'm so sorry for your loss. Sending you my love <3

Oct 11, 2025 View post →
sharkiebytesexe.bsky.social
@sharkiebytesexe.bsky.social · Bluesky

So truee

Oct 11, 2025 View post →
koukoupuffs
@koukoupuffs.bsky.social · Bluesky

So the best outcome would be having less than 10K people qualify. XD I bet there will be a lot of angry voices if the pay out ends up like 20 Primogems each, but I doubt there would be THAT many players that managed to get in. Watch me be wrong.

Oct 11, 2025 View post →
James is here too
@jcjmorris.bsky.social · Bluesky

Right, can we all just agree that the first ever Nobel Prize for Cojones should be awarded to Greta Thunberg this year?

Oct 11, 2025 View post →
allanroyx.bsky.social
@allanroyx.bsky.social · Bluesky

No health care. No freedom of speech. Everyday freedoms Are now out of reach. You'll soon surrender Even more things Unless you shout loudly No more kings.

Oct 11, 2025 View post →
Rosa
@rosaba.bsky.social · Bluesky

Ufff. Que al final somos humanos y se puede esperar cualquier cosa

Oct 11, 2025 View post →
Blue in a Red State
@sheriw.bsky.social · Bluesky

My goodness. That woman’s ugliness has spread to her face to the degree that she is unrecognizable. Sad.

Oct 11, 2025 View post →
Elzanne
@c-elzanne.bsky.social · Bluesky

THE EDDIE GEAR?? CODY. I’m already unnecessarily emotional and you do THIS!! #WWECrownJewel

Oct 11, 2025 View post →
bradley™
@mushqoom.bsky.social · Bluesky

omgggg this is what we need to happen on big brother FUCK!

Oct 11, 2025 View post →
mel
@rabanastre.bsky.social · Bluesky

i feel like the zodiac brave story is meant to be ancient history, or at least predates ajora's time

Oct 11, 2025 View post →
Lil’ Donny B
@lildonnyb.bsky.social · Bluesky

It would not be the death of purple state democrats. Republicans already call Schumer and Jeffries radical lefty terrorists for Christs sake. It’s irrelevant. Where they lose is because they stand for nothing and the party in effect agrees by keeping them in leadership.

Oct 11, 2025 View post →
ara forever
@hedgehodgefax.bsky.social · Bluesky

all the canadians clapping when the plane landed n all the brits lookin around like "huh?"

Oct 11, 2025 View post →
Staatsmätresse Donna
@donnavsdienst.bsky.social · Bluesky

Ja hier wurde sich schon zu Tode gesoffen

Oct 11, 2025 View post →
Michael Pascale
@mpascale.psyc.dev · Bluesky

For a trainee like myself, Lindsay refreshingly weaves together various topics, methods, factoids, and historical anecdotes. Many of these things one encounters in classes or papers, but the

Oct 11, 2025 View post →
Kelly
@kellypaladin.bsky.social · Bluesky

It's been five months since my mom passed away. It's been about a week since I changed the contact in my phone from "Parents" to "Dad."

Oct 11, 2025 View post →
YanaarLee
@yanaarlee.bsky.social · Bluesky

Mike Johnson is hopelessly crazed.., and he's the Speake!!! Govt as we've known it is fucking over! Abolish the presidency altogether and create an Executive Council. DM for the amendment.

Oct 11, 2025 View post →
bones
@tatiuska.bsky.social · Bluesky

Parabéns, felicidades pra vocês!

Oct 11, 2025 View post →
CHRONIC CANADIAN
@grampafan.bsky.social · Bluesky

If Biden had gone into the hospital for an ingrown toenail the republicans would have been shrieking for the 25th amendment.

Oct 11, 2025 View post →
trillionwrong.bsky.social
@trillionwrong.bsky.social · Bluesky

www.joblo.com/jim-caviezel...

Oct 11, 2025 View post →
Drangonzic
@drangonzic.bsky.social · Bluesky

Gotcha, will be lovely to see.

Oct 11, 2025 View post →
Monsieur André
@the.huepfbeuteltier.org · Bluesky

Faschisten planen halt mit Faschisten

Oct 11, 2025 View post →
I have so many names...
@o10tam.bsky.social · Bluesky

Oct 11, 2025 View post →
Oliver Darcy
@oliverdarcy.bsky.social · Bluesky

Reminder that the weekend editions of @status.news are 100% free. Sign up to get them directly in your inbox: status.news/subscribe

Oct 11, 2025 View post →
cojosurfer805
@cojosurfer805.bsky.social · Bluesky

Ya baby!!!☀️

Oct 11, 2025 View post →
Powderkeg
@gloriapissedoff.bsky.social · Bluesky

Saturday Morning Covfefe: 5 Things with Olivia open.substack.com/pub/welivedi...

Oct 11, 2025 View post →
Robert Mahon
@bedform.org · Bluesky

With *maybe* one exception but he's got some other not so great attributes. The clear front runner voted to REMOVE protected bike lanes on the west bank (as did every city councilmember running) so that's a hell no from me

Oct 11, 2025 View post →
【bot】秋も鳴く!セミ強化月間開催中
@besnavel.bsky.social · Bluesky

【AUTO】ミャミャミャー!!

Oct 11, 2025 View post →
Still Merry
@kindamerry.bsky.social · Bluesky

noooo... I hope it's just a loose linkage or something like that :c

Oct 11, 2025 View post →
Massapequa Boy
@democracybydesign.bsky.social · Bluesky

Oct 11, 2025 View post →
Ketracel Black
@ketracelblack.blacksky.app · Bluesky

I'm sorry for this man's family. We can build a world where this doesn't happen but we have to be brave enough to explain why it does.

Oct 11, 2025 View post →
Blue Tapes
@bluetapes.bsky.social · Bluesky

#TheTwen2ie5 Day 11 Bill Orcutt - A Different View (2022, US) (Album version not available on YouTube, so here is a live arrangement by Shane Parish, who produced charts of Bill's music and performed the album on tour as part of Bill's guitar quartet) youtu.be/nWUezvB4wi4?...

Oct 11, 2025 View post →
Chellevina✨
@bomb-chelle.blacksky.app · Bluesky

It really is! Didn’t know it was a thing actually lol

Oct 11, 2025 View post →
LL♎️
@lady-lidiaa.bsky.social · Bluesky

Nie przeginaj

Oct 11, 2025 View post →
Bill in Colorado
@spyvinyl.bsky.social · Bluesky

Oct 11, 2025 View post →
Debbie Moon
@debbiemoon.bsky.social · Bluesky

The howl is me, devouring the forest.

Oct 11, 2025 View post →
Edu Benavente Art
@edubenart.bsky.social · Bluesky

Thank youuu!!!

Oct 11, 2025 View post →
Dave the Milleneeyore
@dhodgs.bsky.social · Bluesky

If they're somehow able to clinch at home next week do we rush the field or?

Oct 11, 2025 · 1 like View post →
Jacg
@jacg1.bsky.social · Bluesky

& of 9/11

Oct 11, 2025 View post →
stella
@dalejennings.bsky.social · Bluesky

eu sonho com essa cena, quero muito ver eles tocando violino juntos e tbm espero muito a cena deles no lugar das bruxas

Oct 11, 2025 View post →
仮面ライダーモア二世
@moamoajump.bsky.social · Bluesky

Oct 11, 2025 View post →
Jaromír Janda
@mct4health · X

@TuckerGoodrich Targeting p21Cip1 highly expressing cells in adipose tissue alleviates insulin resistance in obesity https://t.co/c8yaQtT5PO Lipid peroxidation products induce carbonyl stress, mitochondrial dysfunction, and cellular senescence in human and murine cells https://t.co/GVcQwSh1tA

Apr 27, 2025 · 349 followers View post →
the paper link
@the_paper_link · X

Trend up+15: Monroe TB, ..., Bernlohr DA (Aging Cell) __Lipid peroxidation products induce carbonyl stress, mitochondrial dysfunction, and cellular senescence in human and murine cells__ https://t.co/byeQStgM2T

Oct 15, 2024 · 136 followers View post →