January 2025 PMID 39466903

Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis.

Philippe Généreux, Allan Schwartz, J Bradley Oldemeyer, Philippe Pibarot, David J Cohen, Philipp Blanke, Brian R Lindman, Vasilis Babaliaros, William F Fearon, David V Daniels, Adnan K Chhatriwalla, Clifford Kavinsky, Hemal Gada, Pinak Shah, Molly Szerlip

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Mentions

221

Peak: 80 in Jan 2025

across 7 sources since Oct 2024

Extended reach

3,698,475

potential audience

Total likes

357

Video views

1,245

Mentions per month

Oct 2024 – Nov 2025

Where it's discussed

X / Twitter171 posts
News32 articles
Blogs8 articles
YouTube3 videos
Facebook3 posts
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AI synopsis

What people are saying

Discussions consistently support the findings of the study, citing phrases like 'practice-changing' and 'superior to surveillance,' and referencing the trial's significance with words like 'landmark' and 'exciting results.' The tone is highly positive and focused on clinical advancements, reflecting strong interest and belief in the study's potential to alter current practices.

AgreementStrong agreement

Most discussions highlight support for early TAVR, emphasizing its potential benefits and practice-changing implications, showing strong consensus with the article's findings.

InterestHigh interest

The discussions demonstrate high curiosity about the trial results, clinical impact, and the future of treatment guidelines, reflecting strong engagement and interest.

EngagementHigh engagement

Posts reference detailed trial outcomes, discuss implications for clinical practice, and compare to existing standards, indicating deep engagement.

ImpactHigh impact

The discussions suggest that this research could significantly influence treatment protocols and guidelines for asymptomatic severe AS, indicating high potential impact.

Abstract in brief

Patients with asymptomatic severe aortic stenosis were studied to determine if early TAVR (transcatheter aortic valve replacement) improves outcomes compared to routine clinical surveillance, as current guidelines suggest a lack of definitive data on this topic.
A total of 901 patients, mostly around 76 years old and generally at low surgical risk, were randomly assigned to undergo either TAVR or clinical surveillance, with outcomes measured by the occurrence of death, stroke, or unplanned hospitalizations.
Results indicated that those who underwent TAVR had significantly better outcomes, with only 26.8% experiencing the composite primary endpoint versus 45.3% in the surveillance group, suggesting that early intervention with TAVR can reduce severe complications

Read the full abstract

All mentions

FDA Approves TAVR for Asymptomatic Aortic Stenosis Patients

The FDA approval of TAVR for patients with asymptomatic Aortic Stenosis is discussed. Additionally, the video covers a study comparing subcutaneous and transvenous ICDs, highlighting device-related complications and…

Medscape · May 2, 2025 758 views

Early Aortic Valve Replacement Benefits in Asymptomatic Patients

The AVATAR trial investigated early surgical aortic valve replacement (SAVR) versus conservative treatment in asymptomatic patients with severe aortic stenosis. Results showed that early SAVR significantly reduced major…

Medscape · Feb 28, 2025 420 views

Early TAVR for Severe Asymptomatic Aortic Stenosis Shows Improved Outcomes

This video discusses a study on early transcatheter aortic valve replacement for asymptomatic severe aortic stenosis, indicating that early intervention can reduce complications and improve patient outcomes compared to…

Cardio & News by Dr Caroli · Mar 4, 2025 68 views

International Office, CoM

@iocom_au · X

We are glad to kick off the first Journal Club this year! Topic: Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis Moderated by Dr. Dania Mohty Hosted by Ebraheem Hoda (MS2) Presented by Anan Alharbi, Abduhu Amer, Tala Daqqa, and Lema Sibai (MS3) https://t.co/YkwWsIRT5u

Nov 14, 2025 · 3 likes · 834 followers View post →

Tidal Grace

@Tidal_Grace · X

RT @NEJM: Original Article: Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis (EARLY TAVR trial) https://t.co/…

Oct 6, 2025 · 30 shares · 189 followers View post →

ZaraBlaze

@ZaraBlaze321 · X

RT @drraviele: https://t.co/AHhqiM9Q0P

Jun 13, 2025 · 2 shares · 293 followers View post →

Vumedi Cardio

@Cardio_Vumedi · X

Dr. Philippe Genereux breaks down EARLY TAVR in asymptomatic severe AS, early intervention halved the risk of death, stroke, or CV hospitalization vs surveillance. A pivotal trial with practice-changing potential. Watch the full analysis now on #Vumedi: https://t.co/GGq5N5NJ2N

Jun 2, 2025 · 1 like · 420 followers View post →

Courtney McDonnell

@TheValveNurse · X

Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis | New England Journal of Medicine https://t.co/aiibVvdp4y #SevereAorticStenosis #asymtomaticAS #TAVR #ValveTeam #FDAapproved #patientcare

May 26, 2025 · 5 followers View post →

Dr Nikki Stamp FRACS

@drnikkistamp · X

FDA approving #TAVR for asymptomatic early AS is hardly surprising - AS symptoms may be 'unnoticeable', but the impact to the heart is cumulative. However, #TAVR will need to excel in its results esp. complications and cost https://t.co/jJyPpLQnJD

May 13, 2025 · 21,684 followers View post →

John Zendo

@JohnZendo · X

RT @NEJM: Original Article: Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis (EARLY TAVR trial) https://t.co/…

Apr 16, 2025 · 29 shares · 19 followers View post →

Juan Senior

@jsenior64 · X

EARLY TAVR Trial 2025 https://t.co/XMQU7ZHa8p

Apr 3, 2025 · 11,064 followers View post →

Jerry Valenzuela

@JeraValenzuela · X

RT @DrCCaroli:

Mar 5, 2025 · 5 shares · 167 followers View post →

Augusto Rojas Carrión

@AugustoR04 · X

RT @DrCCaroli:

Mar 5, 2025 · 5 shares · 329 followers View post →

jorge gamboa

@jorgega62811906 · X

RT @DrCCaroli:

Mar 5, 2025 · 5 shares · 64 followers View post →

Juan Pedro Romero

@JuanPedroRome20 · X

RT @DrCCaroli:

Mar 4, 2025 · 5 shares · 205 followers View post →

Carlos Fava

@CarlosFava4 · X

RT @DrCCaroli:

Mar 4, 2025 · 5 shares · 647 followers View post →

Christian Caroli

@DrCCaroli · X

Mar 4, 2025 · 14 likes · 5 shares · 2,408 followers View post →

Wail AlkashkariFSCAI,FPICSوائل القشقرى

@AlkashkariWail · X

RT @mirvatalasnag: @jimcongress @drnvanmieghem @AdamGreenbaumMD @AlkashkariWail @kiadeb87 @amrabbasmd @georgedangas @SCAI Focus on Early…

Feb 21, 2025 · 3 shares · 17,048 followers View post →

JIM Congress

@jimcongress · X

RT @mirvatalasnag: @jimcongress @drnvanmieghem @AdamGreenbaumMD @AlkashkariWail @kiadeb87 @amrabbasmd @georgedangas @SCAI Focus on Early…

Feb 21, 2025 · 3 shares · 265 followers View post →

Chiara De Biase

@kiadeb87 · X

RT @mirvatalasnag: @jimcongress @drnvanmieghem @AdamGreenbaumMD @AlkashkariWail @kiadeb87 @amrabbasmd @georgedangas @SCAI Focus on Early…

Feb 21, 2025 · 3 shares · 1,454 followers View post →

MIЯVΛƬ #IC ༄ ｡°

@mirvatalasnag · X

@jimcongress @drnvanmieghem @AdamGreenbaumMD @AlkashkariWail @kiadeb87 @amrabbasmd @georgedangas @SCAI Focus on Early TAVR @PhilGenereuxMD Young Bicuspid Coronary disease All worth considering

Feb 21, 2025 · 15 likes · 3 shares · 26,024 followers View post →

ALKINDY Abdulrhman

@Abdul_alkindy · X

RT @KhalidFAlhabib: https://t.co/iLVs78m45x

Feb 16, 2025 · 2 shares · 816 followers View post →

Kuchal Agadi

@AgadiKuchal · X

RT @drbennisahmed: EARLY TAVR Trial ACC 2025 Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis strategy of e…

Feb 1, 2025 · 10 shares · 120 followers View post →

がむしゃら院長

@gamushara_incho · X

無症候性の重度大動脈弁狭窄症を見つけれるかどうかがポイント無症候性の重度大動脈弁狭窄症で早期TAVRが死亡や脳卒中などの発生率を有意に低下。大規模無作為化試験より。#TAVR #心臓病 #臨床試験 https://t.co/awQhn1DX5K https://t.co/pf1tzwB4K6

Jan 30, 2025 · 35 followers View post →

Dr Ihab Suliman

@IhabFathiSulima · X

RT @Dr_ibrahimHarbi: “ Early TAVR “ https://t.co/VSEPFGvLwW “ CLEAR SYNERGY “ https://t.co/Iwexgimh49 https://t.co/X0fzh60w9E

Jan 27, 2025 · 1 share · 87,178 followers View post →

إبراهيم الحربي Ibrahim Alharbi

@Dr_ibrahimHarbi · X

“ Early TAVR “ https://t.co/VSEPFGvLwW “ CLEAR SYNERGY “ https://t.co/Iwexgimh49 https://t.co/X0fzh60w9E

Jan 27, 2025 · 4 likes · 1 share · 9,003 followers View post →

Wei-Guo Ma, MD

@Dr_Ma_of_PUMC · X

RT @drbennisahmed: EARLY TAVR Trial ACC 2025 Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis strategy of e…

Jan 27, 2025 · 10 shares · 2,364 followers View post →

Carlos F. Matute-Martínez

@Felipe_Matute · X

Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis | New England Journal of Medicine https://t.co/AeoGGpEWlo

Jan 27, 2025 · 214 followers View post →

Hassan Al-Harith

@h_a_progress · X

RT @drbennisahmed: EARLY TAVR Trial ACC 2025 Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis strategy of e…

Jan 27, 2025 · 10 shares · 5 followers View post →

juan ramon

@RamonTasmania · X

RT @drbennisahmed: EARLY TAVR Trial ACC 2025 Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis strategy of e…

Jan 27, 2025 · 10 shares · 92 followers View post →

Andrew Evans

@healthtechdrew · X

RT @drbennisahmed: EARLY TAVR Trial ACC 2025 Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis strategy of e…

Jan 27, 2025 · 10 shares · 22 followers View post →

我闯入猫的城镇

@scarlett_viven · X

RT @drbennisahmed: EARLY TAVR Trial ACC 2025 Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis strategy of e…

Jan 27, 2025 · 10 shares · 50 followers View post →

nike

@wot_mikey · X

RT @drbennisahmed: EARLY TAVR Trial ACC 2025 Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis strategy of e…

Jan 27, 2025 · 10 shares · 462 followers View post →

Gurjaspreet Kaur Bhattal

@GBhattal_MD · X

RT @drbennisahmed: EARLY TAVR Trial ACC 2025 Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis strategy of e…

Jan 26, 2025 · 10 shares · 257 followers View post →

د . احمد سمان

@Ahmed43101178 · X

RT @drbennisahmed: EARLY TAVR Trial ACC 2025 Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis strategy of e…

Jan 26, 2025 · 10 shares · 6,359 followers View post →

Ahmed Bennis MD

@drbennisahmed · X

Jan 26, 2025 · 31 likes · 10 shares · 2,638 followers View post →

STITCHES Medicine - the Best of Medical Research

@STITCHESMed · X

Early TAVR significantly reduced death, stroke, or unplanned hospitalizations compared to clinical surveillance in asymptomatic severe aortic stenosis patients. by Généreux P, Schwartz A (...) Sheth T et 16 al. in N Engl J Med https://t.co/AffKT2nf2n #MedX #MedResearch

Jan 25, 2025 · 82 followers View post →

Matt Daniels MD PhD

@cardiacpolymath · X

RT @MCoylewright: Is it safe to watch severe AS? Debate today @CSIAmerica on unplanned hospitalization as trial endpoint. Check out supp ta…

Jan 23, 2025 · 1 share · 2,985 followers View post →

megan coylewright md mph

@MCoylewright · X

Is it safe to watch severe AS? Debate today @CSIAmerica on unplanned hospitalization as trial endpoint. Check out supp table to see what landed patients in hospital when waiting. TAVR in Asymptomatic Severe Aortic Stenosis | NEJM https://t.co/dcoveaNAcg

Jan 23, 2025 · 2 likes · 1 share · 1,987 followers View post →

東北大学循環器内科

@cardio_tu · X

2 min cardiology（臨床、担当：小沼翔） Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis P Genereux et al. NEJM 28 Oct, 2024 https://t.co/NDIKOvQJsT →

Jan 20, 2025 · 1 like · 1,312 followers View post →

DarkQueen

@DraNajrit · X

RT @NEJM: In the EARLY TAVR trial, researchers assessed whether early transcatheter aortic-valve replacement (TAVR) would lead to better ou…

Jan 20, 2025 · 12 shares · 1,396 followers View post →

Manoj Mayogi Mishra

@mayogisense · X

RT @NEJM: In the EARLY TAVR trial, researchers assessed whether early transcatheter aortic-valve replacement (TAVR) would lead to better ou…

Jan 20, 2025 · 12 shares · 573 followers View post →

Sanal MG

@sanalmg · X

RT @NEJM: In the EARLY TAVR trial, researchers assessed whether early transcatheter aortic-valve replacement (TAVR) would lead to better ou…

Jan 20, 2025 · 12 shares · 90 followers View post →

Habib Cissé

@Kissiland_man · X

RT @NEJM: In the EARLY TAVR trial, researchers assessed whether early transcatheter aortic-valve replacement (TAVR) would lead to better ou…

Jan 20, 2025 · 12 shares · 893 followers View post →

Nouf Al hemmadi

@NoufAhmedAlham2 · X

RT @NEJM: In the EARLY TAVR trial, researchers assessed whether early transcatheter aortic-valve replacement (TAVR) would lead to better ou…

Jan 20, 2025 · 12 shares · 1,273 followers View post →

Joseph Grover

@JGroverEMSDoc · X

Interesting study looking at early TAVR vs surveillance for severe AS. It would seem this should lead to early intervention even in asymptomatic patients. https://t.co/1jj44PGw3N

Jan 20, 2025 · 2 likes · 2 shares · 161 followers View post →

Eric

@ericsophia12 · X

RT @NEJM: In the EARLY TAVR trial, researchers assessed whether early transcatheter aortic-valve replacement (TAVR) would lead to better ou…

Jan 20, 2025 · 12 shares · 97 followers View post →

Dr.Ezhil Mugunthan

@Ezhil_mugunthan · X

RT @NEJM: In the EARLY TAVR trial, researchers assessed whether early transcatheter aortic-valve replacement (TAVR) would lead to better ou…

Jan 20, 2025 · 12 shares · 60 followers View post →

Joshua Kimbrell

@joshkimbre · X

RT @NEJM: In the EARLY TAVR trial, researchers assessed whether early transcatheter aortic-valve replacement (TAVR) would lead to better ou…

Jan 20, 2025 · 12 shares · 1,611 followers View post →

NEJM

@NEJM · X

Jan 20, 2025 · 60 likes · 12 shares · 935,591 followers View post →

医療法人社団ゆみの

@yumino_medical · X

【DrゆみのWeekly Journal Scan】＊無症候性ASに対するTAVR from NEJM＊ https://t.co/jceHkrgnEy 無症候性重度大動脈弁狭窄（AS）患者に対し、経カテーテル大動脈弁置換術（TAVR）の早期介入が有効かどうかを検証するための多施設ランダム化試験（EARLY

Jan 19, 2025 · 8 likes · 1,226 followers View post →

Salvador Pedraza

@salvasapedraza · X

Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis. https://t.co/r5iAc3tOWi https://t.co/nwpC1PS7Ep

Jan 19, 2025 · 1 like · 6,523 followers View post →

Khalid Minhas, MD FACC

@minhaskh · X

RT @drraviele: https://t.co/AHhqiM9Q0P

Jan 19, 2025 · 2 shares · 11,344 followers View post →

Raviele Antonio

@drraviele · X

https://t.co/AHhqiM9Q0P

Jan 19, 2025 · 2 shares · 23,301 followers View post →

echoka

@t_dakao · X

RT @NEJM: Original Article: Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis (EARLY TAVR trial) https://t.co/…

Jan 19, 2025 · 29 shares · 379 followers View post →

Piluca Martin-Davila

@DavilaPiluca · X

RT @NEJM: Original Article: Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis (EARLY TAVR trial) https://t.co/…

Jan 19, 2025 · 29 shares · 609 followers View post →

Ian Weissman, DO

@DrIanWeissman · X

RT @Nigelj08223326: Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis | New England Journal of Medicine https:…

Jan 18, 2025 · 1 share · 43,057 followers View post →

Truthoverdishonesty

@Nigelj08223326 · X

Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis | New England Journal of Medicine https://t.co/09nQpFNw3T @DrIanWeissman @juniorjuri Intervention with TAVI is better than surveillance

Jan 18, 2025 · 6 likes · 1 share · 1,611 followers View post →

mdk

@ccionuomision · X

https://t.co/G1cI4PJgXw

Jan 18, 2025 · 106 followers View post →

Ivan Shekerev

@ShekerevMD · X

RT @NEJM: Original Article: Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis (EARLY TAVR trial) https://t.co/…

Jan 18, 2025 · 29 shares · 433 followers View post →

Mneee3

@crafty8798 · X

RT @NEJM: Original Article: Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis (EARLY TAVR trial) https://t.co/…

Jan 18, 2025 · 29 shares · 290 followers View post →

John P Erwin III MD MBA MACC (#BigPoppy )

@HeartOTXHeartMD · X

RT @NEJM: Original Article: Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis (EARLY TAVR trial) https://t.co/…

Jan 18, 2025 · 29 shares · 39,655 followers View post →

Jose Luis Díez Gil

@JL_10_HILL · X

RT @NEJM: Original Article: Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis (EARLY TAVR trial) https://t.co/…

Jan 18, 2025 · 29 shares · 1,342 followers View post →

Carles Falces

@CarlesFalces · X

RT @NEJM: Original Article: Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis (EARLY TAVR trial) https://t.co/…

Jan 18, 2025 · 29 shares · 2,691 followers View post →

Marjorie

@SitiBad94 · X

RT @VictorDayan1: The power of randomization in open blinded trials….it gets almost 30% of patients with AS who were asymptomatic for years…

Jan 17, 2025 · 38 shares · 213 followers View post →

Dhruva Biswas, MD/PhD

@dhruva_biswas · X

RT @NEJM: Original Article: Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis (EARLY TAVR trial) https://t.co/…

Jan 17, 2025 · 29 shares · 591 followers View post →

Valva Mitralis

@Mitrovalvology · X

RT @NEJM: Original Article: Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis (EARLY TAVR trial) https://t.co/…

Jan 17, 2025 · 29 shares · 4,131 followers View post →

EOLO MORANDI JR.

@eolojr · X

RT @NEJM: Original Article: Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis (EARLY TAVR trial) https://t.co/…

Jan 17, 2025 · 29 shares · 539 followers View post →

Regina Dalmau

@reginadalmau · X

RT @NEJM: Original Article: Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis (EARLY TAVR trial) https://t.co/…

Jan 17, 2025 · 29 shares · 4,459 followers View post →

H. El-Sourani

@el_sourani · X

RT @NEJM: Original Article: Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis (EARLY TAVR trial) https://t.co/…

Jan 17, 2025 · 29 shares · 159 followers View post →

esteban rengel

@estebanrengel · X

RT @NEJM: Original Article: Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis (EARLY TAVR trial) https://t.co/…

Jan 17, 2025 · 29 shares · 33 followers View post →

Jay Khambhati

@JKhambhati · X

RT @NEJM: Original Article: Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis (EARLY TAVR trial) https://t.co/…

Jan 17, 2025 · 29 shares · 1,506 followers View post →

Dr. Shashank Joshi

@AskDrShashank · X

RT @NEJM: Original Article: Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis (EARLY TAVR trial) https://t.co/…

Jan 17, 2025 · 29 shares · 32,520 followers View post →

Omar Chehab, MD, MSc

@OmarChehab1 · X

RT @NEJM: Original Article: Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis (EARLY TAVR trial) https://t.co/…

Jan 17, 2025 · 29 shares · 1,842 followers View post →

Pat

@Hlth_News · X

RT @NEJM: Original Article: Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis (EARLY TAVR trial) https://t.co/…

Jan 17, 2025 · 29 shares · 702 followers View post →

Fadi Khalil

@fadi_grace · X

RT @NEJM: Original Article: Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis (EARLY TAVR trial) https://t.co/…

Jan 17, 2025 · 29 shares · 1 followers View post →

Seigo Izumo

@SeigoIzumo · X

RT @NEJM: Original Article: Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis (EARLY TAVR trial) https://t.co/…

Jan 17, 2025 · 29 shares · 3,968 followers View post →

Pawan Rao MD, FASN

@nephronus · X

RT @NEJM: Original Article: Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis (EARLY TAVR trial) https://t.co/…

Jan 17, 2025 · 29 shares · 994 followers View post →

Powell Kafwanka, MBChB, MSc

@PowellKafwanka · X

RT @NEJM: Original Article: Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis (EARLY TAVR trial) https://t.co/…

Jan 17, 2025 · 29 shares · 91 followers View post →

Dr. Sue Gross

@DrSueGross · X

RT @NEJM: Original Article: Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis (EARLY TAVR trial) https://t.co/…

Jan 16, 2025 · 29 shares · 3,030 followers View post →

William Frankel

@williamcfrankel · X

RT @NEJM: Original Article: Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis (EARLY TAVR trial) https://t.co/…

Jan 16, 2025 · 29 shares · 2,490 followers View post →

Juan Pedro Romero

@JuanPedroRome20 · X

RT @NEJM: Original Article: Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis (EARLY TAVR trial) https://t.co/…

Jan 16, 2025 · 29 shares · 205 followers View post →

Yonemoto N

@nyonenyone · X

RT @NEJM: Original Article: Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis (EARLY TAVR trial) https://t.co/…

Jan 16, 2025 · 29 shares · 1,272 followers View post →

Yonemoto N

@nyonenyone · X

RT @NEJM: New in the January 16, 2025, issue of NEJM: TAVR for Asymptomatic Severe Aortic Stenosis (EARLY TAVR trial) https://t.co/bmCLd…

Jan 16, 2025 · 4 shares · 1,272 followers View post →

Habib Cissé

@Kissiland_man · X

RT @NEJM: Original Article: Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis (EARLY TAVR trial) https://t.co/…

Jan 16, 2025 · 29 shares · 893 followers View post →

Grabbir Boubi

@GrabbirBoubee · X

RT @NEJM: Original Article: Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis (EARLY TAVR trial) https://t.co/…

Jan 16, 2025 · 29 shares · 6 followers View post →

ريم الكيلاني

@geneCulinary · X

RT @NEJM: Original Article: Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis (EARLY TAVR trial) https://t.co/…

Jan 16, 2025 · 29 shares · 5 followers View post →

Hany Ragy

@Hragy · X

RT @NEJM: New in the January 16, 2025, issue of NEJM: TAVR for Asymptomatic Severe Aortic Stenosis (EARLY TAVR trial) https://t.co/bmCLd…

Jan 16, 2025 · 4 shares · 80,365 followers View post →

NEJM

@NEJM · X

Jan 16, 2025 · 90 likes · 29 shares · 935,591 followers View post →

Kimberley

@MollyDu127 · X

RT @acorderofort: Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis @NEJM

Jan 16, 2025 · 1 share · 286 followers View post →

旅人 tabito

@tabibito250 · X

Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis | New England Journal of Medicine https://t.co/abF4mBkmcG

Jan 16, 2025 · 1 like · 1,076 followers View post →

NEJM

@NEJM · X

Jan 16, 2025 · 26 likes · 4 shares · 935,591 followers View post →

johan RBH boie

@jobo1111 · X

Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis | New England Journal of Medicine https://t.co/aV0Z94A6pT

Jan 16, 2025 · 407 followers View post →

Alberto Cordero

@acorderofort · X

Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis @NEJM

Jan 16, 2025 · 4 likes · 1 share · 4,887 followers View post →

Julian P Villacastin

@jvillacastin · X

Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis https://t.co/LYqdb43d8G https://t.co/4LZZw5Mt4I

Jan 16, 2025 · 1 like · 23,335 followers View post →

Professor M Z Khalil

@mzkhalil · X

Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis | NEJM A strategy of early #TAVR was superior to clinical surveillance in reducing the incidence of death, stroke, or unplanned hospitalization for cardiovascular causes. https://t.co/iImTiLtXim https://t.co/OHAG8aehNu

Jan 15, 2025 · 4 likes · 2,855 followers View post →

総合診療医Andy

@Tak0123 · X

65歳以上の無症状のSevere ASに対して、早期のTAVRは、死亡、脳卒中、予定外の心血管病による入院の複合アウトカムを減らす（26.8% vs 45.3%) 無症状のASの紹介閾値が変わりそうな研究ですね https://t.co/LrVjy57DNM

Jan 15, 2025 · 9 likes · 2,139 followers View post →

Jan Hartmann, MD

@JanHartmannMD · X

Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis | New England Journal of Medicine https://t.co/L1L2c0lknM

Jan 15, 2025 · 308 followers View post →

George Ferzli

@drferzli · X

Among patients with asymptomatic severe aortic stenosis, a strategy of early TAVR was superior to clinical surveillance in reducing the incidence of death, stroke, or unplanned hospitalization for cardiovascular causes. New England Journal of Medicine https://t.co/m2rqz8nppF

Jan 15, 2025 · 378 followers View post →

Segun Olusanya (He/Him) iceman_ex@critcare.social

@iceman_ex · X

Interesting recentl trials in AS: 1. early TAVR- early TAVI in asymptomatic severe AS https://t.co/oRvVAcPuQQ Primary end point was composite of hospitalisations/death etc 19% ARR

Jan 10, 2025 · 5 likes · 19,585 followers View post →

Stacey Hilliar

@HilliarStacey · X

RT @DrDamluji: Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis: @NEJM

Jan 3, 2025 · 94 shares · 261 followers View post →

Dr. Faisal Rahman

@frahman480 · X

@JAMACardio https://t.co/Db82I517WT Excellent review to help understand why #aorticstenosis and why treating asymptomatic disease may be beneficial in #EARLYTAVR trial @EdwardsLifesci https://t.co/ysHsKV8xxi @NEJM https://t.co/MZzoboMrVk

Jan 1, 2025 · 1 like · 771 followers View post →

Dr. Faisal Rahman

@frahman480 · X

@JAMACardio Excellent review of #aorticstenosis https://t.co/3sA4cZ73ZQ Helps make sense of the findings of #EARLYTAVR trial (https://t.co/ysHsKV95mQ) and consideration of #TAVR in asymptomatic pts. https://t.co/4JxADSMEhk

Jan 1, 2025 · 771 followers View post →

Khanchouch Faicel

@KhanchouchFaic1 · X

RT @vass_vassiliou: EARLY TAVR put @NEJM - early TAVR for asymptomatic severe Aortic Stenosis- astonishing results fully supportive of earl…

Dec 26, 2024 · 35 shares · 983 followers View post →

Yetunde Kemi Fatade, MD, MPH

@joyfuldockemi · X

RT @OrgCardiology:

Dec 8, 2024 · 5 shares · 1,231 followers View post →

Ogunniyi Research Group (ORG)

@orgcardiology.bsky.social · Bluesky

Dec 8, 2024 · 4 likes · 5 shares View post →

リハヒロ（Hiroshi Shoji）

@RehaHiro · X

無症候性重度大動脈弁狭窄症に対すて予防的TAVIを支持。アブストのみ。 https://t.co/PmeXfv4VCo

Dec 8, 2024 · 238 followers View post →

Anita Osabutey MD MPH

@dr_Carmi · X

RT @OrgCardiology:

Dec 7, 2024 · 5 shares · 283 followers View post →

Joshua Stephens, MD

@therealjosh_s · X

RT @OrgCardiology:

Dec 7, 2024 · 5 shares · 886 followers View post →

Modele Ogunniyi, MD, MPH

@modeldoc · X

RT @OrgCardiology:

Dec 7, 2024 · 5 shares · 3,356 followers View post →

ORG

@OrgCardiology · X

Dec 7, 2024 · 8 likes · 5 shares · 60 followers View post →

Suraj Kannan

@TheSurajKannan · X

Finally got around to reading EARLY-TAVR. Still learning about endpoint design (for example - I still don't fully understand controversies about HF trial endpoints), but this one seems obvi questionable. Not sure there's enough to change guidelines. https://t.co/74G07IPM0S

Dec 1, 2024 · 762 followers View post →

Yousef Alshehri | يوسف الشهري

@YousefAlshehrri · X

آخر الأبحاث.. https://t.co/jsrGZuWXAk https://t.co/IEtbeNnfLe

Nov 28, 2024 · 1 like · 659 followers View post →

Venk Murthy MD PhD

@venkmurthy · X

@ProfDFrancis @mugander @rajkumar_chris @drjohnm @rallamee @bnallamo Direct link below. Bottom of Page 15 https://t.co/NpZydnkd8v

Nov 24, 2024 · 1 like · 22,349 followers View post →

Shu-I Lin

@yardbird881 · X

https://t.co/h8DOGOlpZZ

Nov 17, 2024 · 10 followers View post →

Consejo de Cardiología Clínica y Terapéutica

@clinicasac · X

✋Importantes limitaciones https://t.co/CFzcZLpoNA

Nov 14, 2024 · 2 likes · 8,093 followers View post →

nicola d'aurizio

@nicoladarizio · X

RT @DrDamluji: Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis: @NEJM

Nov 11, 2024 · 94 shares · 47 followers View post →

Jose Marquez

@JoseMarquezCard · X

RT @SantasEnrique: TAVI vs seguimiento clínico en pacientes con EAo grave asintomática #TCT @NEJM EARLY TAVR trial 901

Nov 6, 2024 · 6 shares · 228 followers View post →

Proyecto CarPriMur

@carprimur · X

RT @SantasEnrique: TAVI vs seguimiento clínico en pacientes con EAo grave asintomática #TCT @NEJM EARLY TAVR trial 901

Nov 6, 2024 · 6 shares · 7,226 followers View post →

Juan Tormo Molina

@Sieteenpunto · X

En pacientes con estenosis aórtica severa, asintomáticos, el reemplazo valvular por cateterismo redujo la incidencia de muerte, ictus y hospitalización comparado con sólo vigilancia clínica. https://t.co/SBnDiRWd38

Nov 4, 2024 · 194 followers View post →

Kurt Pfeifer

@KurtPfeifer · X

Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis | New England Journal of Medicine https://t.co/ySBzAd0TZb

Nov 4, 2024 · 1 like · 1,130 followers View post →

Eric Widera, MD

@EWidera · X

@dwsir @alzassociation I feel that if you are going to zoom in on the y axis, it should be done as a inset, like in this NEJM study of TAVR for Asymptomatic Severe Aortic Stenosis. https://t.co/QnrD5vDLav https://t.co/VxP1oWu2jJ

Nov 3, 2024 · 1 like · 15,122 followers View post →

Jose Luis Díez Gil

@JL_10_HILL · X

RT @josalar13: EARLY‐TAVR. Landmark study ‼️ In ASYMPTOMATIC Severe Aortic Stenosis: ▶️Early TAVR superior to Clinical surveillance…

Nov 3, 2024 · 2 shares · 1,342 followers View post →

ACI-SEC: Hemodinamica

@shci_sec · X

RT @josalar13: EARLY‐TAVR. Landmark study ‼️ In ASYMPTOMATIC Severe Aortic Stenosis: ▶️Early TAVR superior to Clinical surveillance…

Nov 3, 2024 · 2 shares · 5,741 followers View post →

Primastcar

@primastcar · X

Nov 2, 2024 · 2,341 followers View post →

Pierre McCabe

@PierreMcCabeMD · X

Félicitation @PhilGenereuxMD ! A great publication! Congrats

Nov 2, 2024 · 1 like · 760 followers View post →

Philippe Genereux

@PhilGenereuxMD · X

https://t.co/jkkn3lOFLg

Nov 2, 2024 · 2 likes · 4,351 followers View post →

Josean Alarcon

@josalar13 · X

EARLY‐TAVR. Landmark study ‼️ In ASYMPTOMATIC Severe Aortic Stenosis: ▶️Early TAVR superior to Clinical surveillance in reducing death, stroke or unplanned hospitalization for cardiovasc. causes. @secardiologia @EACVIPresident @shci_sec @JovenesSec https://t.co/dIyk3aVcsq

Nov 1, 2024 · 1 like · 2 shares · 915 followers View post →

Anesthesia Camp

@anesthesiacamp · X

"Among patients with asymptomatic severe aortic stenosis...early TAVR was superior to clinical surveillance in reducing... death, stroke, or unplanned CV hospitalization." NYT: https://t.co/5j1ucZjsmE NEJM abstract: https://t.co/SAHrPB49Iq NEJM PDF: https://t.co/7xHsnmDgdo https://t.co/OIaUHKuspg

Oct 31, 2024 · 928 followers View post →

Domingo Ruiz Hidalgo

@DomingoRuizHid2 · X

https://t.co/eIxTLqzmeo

Oct 31, 2024 · 147 followers View post →

H. El-Sourani

@el_sourani · X

RT @NEJM: Original Article: Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis (EARLY TAVR) https://t.co/bmCLd0…

Oct 31, 2024 · 8 shares · 159 followers View post →

Mathias Orban

@maorban · X

RT @VictorDayan1: The power of randomization in open blinded trials….it gets almost 30% of patients with AS who were asymptomatic for years…

Oct 31, 2024 · 38 shares · 174 followers View post →

Julian P Villacastin

@jvillacastin · X

Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis | New England Journal of Medicine https://t.co/LYqdb43d8G

Oct 31, 2024 · 2 likes · 23,335 followers View post →

Syed Shahrul Naz

@drshahrul80 · X

RT @DrDamluji: Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis: @NEJM

Oct 31, 2024 · 94 shares · 6,925 followers View post →

DiveDoc

@LJLMD · X

RT @EricTopol: Challenging the adage "If it ain't broke, don't fix it." People with severe aortic stenosis— without any symptoms— benefited…

Oct 30, 2024 · 22 shares · 4,692 followers View post →

Dr. Manuel Mendez

@manumenfer · X

RT @DrDamluji: Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis: @NEJM

Oct 30, 2024 · 94 shares · 214 followers View post →

Blake Nield

@MADTurnUP · X

RT @VictorDayan1: The power of randomization in open blinded trials….it gets almost 30% of patients with AS who were asymptomatic for years…

Oct 30, 2024 · 38 shares · 184 followers View post →

EOLO MORANDI JR.

@eolojr · X

RT @FCademartiri: EARLY TAVR trial Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis NCT03042104 The article…

Oct 30, 2024 · 4 shares · 539 followers View post →

Sintayehu Abebe

@sinta_gf · X

RT @ZHeart11768530:

Oct 30, 2024 · 1 share · 450 followers View post →

The Heart

@ZHeart11768530 · X

Oct 30, 2024 · 2 likes · 1 share · 32,856 followers View post →

Savvas Nicolaou, MD

@EmergTraumaRad · X

RT @FCademartiri: EARLY TAVR trial Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis NCT03042104 The article…

Oct 30, 2024 · 4 shares · 1,368 followers View post →

Mounir Basalus (Ⲃⲁⲥⲓⲗⲓⲟⲥ)

@Basalus · X

RT @FCademartiri: EARLY TAVR trial Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis NCT03042104 The article…

Oct 30, 2024 · 4 shares · 4,954 followers View post →

د . احمد سمان

@Ahmed43101178 · X

RT @FCademartiri: EARLY TAVR trial Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis NCT03042104 The article…

Oct 30, 2024 · 4 shares · 6,359 followers View post →

Dr. Filippo Cademartiri

@FCademartiri · X

EARLY TAVR trial Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis NCT03042104 The article examines a trial on transcatheter aortic-valve replacement (TAVR) for patients with asymptomatic severe aortic stenosis (AS). Typically, clinical guidelines https://t.co/UWSni3m5Wn

Oct 30, 2024 · 8 likes · 4 shares · 2,785 followers View post →

Arturo J. Uscanga Padrón

@Arthu_uscanga · X

RT @DrDamluji: Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis: @NEJM

Oct 30, 2024 · 94 shares · 262 followers View post →

Abstream

@abstreamme · X

Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis #science #publication #research #publications https://t.co/8BsThgR1Ea

Oct 30, 2024 · 788 followers View post →

Zaigham Chughtai

@zaighamchughtai · X

RT @DrDamluji: Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis: @NEJM

Oct 30, 2024 · 94 shares · 149 followers View post →

EOLO MORANDI JR.

@eolojr · X

RT @DrDamluji: Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis: @NEJM

Oct 30, 2024 · 94 shares · 539 followers View post →

Ahmed M. El Said

@medox1234 · X

RT @DrDamluji: Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis: @NEJM

Oct 30, 2024 · 94 shares · 2,053 followers View post →

Misako TOKI

@misako_desu · X

RT @DrDamluji: Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis: @NEJM

Oct 30, 2024 · 94 shares · 938 followers View post →

Geoff Wong

@DrGeoffWong · X

RT @DrDamluji: Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis: @NEJM

Oct 30, 2024 · 94 shares · 512 followers View post →

Jaymin S Shah

@JayminSShah1 · X

RT @DrDamluji: Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis: @NEJM

Oct 30, 2024 · 94 shares · 262 followers View post →

Walid Alkeridy وليد الكريدي

@WalidAlkeridy · X

RT @DrDamluji: Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis: @NEJM

Oct 30, 2024 · 94 shares · 1,289 followers View post →

AhmedMugharbil

@MdMugharbil · X

RT @DrDamluji: Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis: @NEJM

Oct 29, 2024 · 94 shares · 241 followers View post →

bujaj49

@bujaj49 · X

RT @DrDamluji: Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis: @NEJM

Oct 29, 2024 · 94 shares · 1,040 followers View post →

Vincent Sachs

@VincentSachs · X

RT @DrDamluji: Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis: @NEJM

Oct 29, 2024 · 94 shares · 30 followers View post →

Kamal Ilyas

@kamalkilyas · X

RT @DrDamluji: Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis: @NEJM

Oct 29, 2024 · 94 shares · 57 followers View post →

Dr. C. P. Thakur

@itscpthakur · X

RT @NEJM: Original Article: Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis (EARLY TAVR) https://t.co/bmCLd0…

Oct 29, 2024 · 8 shares · 39 followers View post →

Gigi Liu

@G2Disrupt · X

RT @DrDamluji: Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis: @NEJM

Oct 29, 2024 · 94 shares · 1,691 followers View post →

Areen Basman Al-Taie, MD, FACC

@AreenMD · X

RT @DrDamluji: Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis: @NEJM

Oct 29, 2024 · 94 shares · 344 followers View post →

Jerry Valenzuela

@JeraValenzuela · X

RT @DrDamluji: Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis: @NEJM

Oct 29, 2024 · 94 shares · 167 followers View post →

dachuang wei

@Dr_littleheart · X

RT @DrDamluji: Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis: @NEJM

Oct 29, 2024 · 94 shares · 31 followers View post →

Shaunak Mangeshkar, MD.

@ShaunakAFC · X

RT @DrDamluji: Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis: @NEJM

Oct 29, 2024 · 94 shares · 1,045 followers View post →

Bartosz Rymuza

@BartoszRymuza · X

RT @DrDamluji: Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis: @NEJM

Oct 29, 2024 · 94 shares · 4 followers View post →

emily pastfield

@PASTIE81 · X

RT @DrDamluji: Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis: @NEJM

Oct 29, 2024 · 94 shares · 255 followers View post →

ricksouu

@ricksou_oket · X

RT @DrDamluji: Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis: @NEJM

Oct 29, 2024 · 94 shares · 53 followers View post →

Prakriti Gaba

@PrakritiGaba · X

RT @NEJM: Original Article: Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis (EARLY TAVR) https://t.co/bmCLd0…

Oct 29, 2024 · 8 shares · 10,668 followers View post →

Obayda Azizy

@O_Azizy_MD · X

RT @DrDamluji: Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis: @NEJM

Oct 29, 2024 · 94 shares · 4,896 followers View post →

andr€

@Andreesitt0 · X

RT @DrDamluji: Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis: @NEJM

Oct 29, 2024 · 94 shares · 90 followers View post →

Steven Castillo

@StevenC0527 · X

RT @DrDamluji: Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis: @NEJM

Oct 29, 2024 · 94 shares · 75 followers View post →

Cyril Nijs, MD

@cyrilnijs · X

RT @DrDamluji: Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis: @NEJM

Oct 29, 2024 · 94 shares · 145 followers View post →

Alex Halstead DNP, FNP-BC, CRNA

@alex_crna · X

RT @DrDamluji: Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis: @NEJM

Oct 29, 2024 · 94 shares · 153 followers View post →

義一YOSHIKAZU.YOSHIKAZU零

@5Iu0cZWla0sxrni · X

RT @EARL_med_tw: N Engl J Med 2024 Oct.28

Oct 29, 2024 · 2 shares · 5,556 followers View post →

5910siki

@5910mikiya · X

RT @EARL_med_tw: N Engl J Med 2024 Oct.28

Oct 28, 2024 · 2 shares · 594 followers View post →

EARLの医学&AIノート

@EARL_med_tw · X

N Engl J Med 2024 Oct.28

Oct 28, 2024 · 8 likes · 2 shares · 147,595 followers View post →

Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis.

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Early Aortic Valve Replacement Benefits in Asymptomatic Patients

Early TAVR for Severe Asymptomatic Aortic Stenosis Shows Improved Outcomes