December 2024 PMID 39482487

The 24-hour molecular landscape after exercise in humans reveals MYC is sufficient for muscle growth.

Sebastian Edman, Ronald G Jones Iii, Paulo R Jannig, Rodrigo Fernandez-Gonzalo, Jessica Norrbom, Nicholas T Thomas, Sabin Khadgi, Pieter J Koopmans, Francielly Morena, Toby L Chambers, Calvin S Peterson, Logan N Scott, Nicholas P Greene, Vandre C Figueiredo, Christopher S Fry

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Mentions

67
Peak: 24 in Oct 2024
across 4 sources since Oct 2024

Extended reach

232,925
potential audience

Total likes

489

Video views

5,559

Mentions per month

Oct 2024 – Feb 2025

Where it's discussed

  • X / Twitter52 posts
  • News9 articles
  • YouTube3 videos
  • Blogs3 articles

AI synopsis

What people are saying

Discussions surrounding the article prominently highlight its implications, with comments like 'Congrats to 1st authors!' and references to the importance of MYC in muscle growth. The celebratory tone and emphasis on the research's innovative aspects, such as 'temporal resource for understanding molecular adaptations,' reflect a strong engagement with the content and acknowledge the study's relevance in advancing knowledge in muscle biology.

AgreementModerate agreement

Most discussions show a positive inclination toward the findings, indicating common support for the conclusions.

InterestHigh interest

There is a high level of curiosity and relevance expressed in these posts, suggesting that the topic resonates with many individuals in the field.

EngagementModerate engagement

The depth of engagement appears moderate, with users referencing specific details and implications but not delving deeply into critiques or analyses.

ImpactHigh impact

Many participants perceive the research to have significant implications for muscle growth treatments and exercise science.

Abstract in brief

  • A study on how skeletal muscle responds to resistance exercise reveals important molecular changes that can help develop treatments to boost muscle mass.
  • Key findings include a timeline of genetic responses: immediate DNA changes at 30 minutes, surges in translation and transcription-related factors between 3 to 8 hours, and peak protein-coding gene expression at 8 hours.
  • Testing showed that increasing the MYC protein in muscle can promote muscle growth and larger muscle fibers in mice, pointing to MYC's critical role in muscle hypertrophy after exercise.

Top posts

Most liked on X and Bluesky
Kevin Murach
@KevinMurachPhD · X

A 5+ year odyssey with @FerdinandvW “The 24-hour molecular landscape after exercise in humans reveals MYC is sufficient for muscle growth” in @emboreports https://t.co/8gfd52FCDG Congrats to 1st authors! @SebastianEdman @RonaldGJones3 Database: https://t.co/y1hmLXWUtf #myotwitter

Oct 31, 2024 · 99 likes · 23 shares · 2,977 followers View post →
Daniel J Drucker
@DanielJDrucker · X

A temporally resolved resource for understanding molecular adaptations to resistance #exercise in human muscle https://t.co/gJCNj6n6ry https://t.co/KWJX2kvWak

Nov 2, 2024 · 45 likes · 12 shares · 34,249 followers View post →
Muscle Cell News
@musclecellnews · X

Nov 8, 2024 · 19 likes · 4 shares · 3,191 followers View post →
DSHB
@DSHB_antibodies · X

Feb 17, 2025 · 7 likes · 3 shares · 2,025 followers View post →
Agingdoc
@agingdoc1 · X

The 24-hour molecular landscape after exercise in humans reveals MYC is sufficient for muscle growth https://t.co/7nmXywM2Le https://t.co/rrgODvBmok

Nov 1, 2024 · 5 likes · 41,609 followers View post →
EMBO Reports
@emboreports · X

The 24-hour molecular landscape after exercise in humans reveals MYCis sufficient for muscle growth. https://t.co/dydQymFhzW https://t.co/9GbxEKK9oN https://t.co/AUVneRZmO3

Oct 31, 2024 · 5 likes · 3 shares · 15,893 followers View post →

All mentions

The Role of MYC in Muscle Growth Post-Exercise

This video explores how the MYC gene influences muscle growth in response to exercise. Key findings indicate that MYC levels peak 8 hours post-exercise, crucially affecting recovery and muscle-building. Research also…

Fitness School · Dec 8, 2024 5 views
Alejandro García Núñez
@AleGarNu81 · X

RT @DSHB_antibodies:

Feb 17, 2025 · 3 shares · 110 followers View post →
Hao Yin
@HaoYin20 · X

RT @DSHB_antibodies:

Feb 17, 2025 · 3 shares · 12,284 followers View post →
Douglas W. Houston
@dw_houston · X

RT @DSHB_antibodies:

Feb 17, 2025 · 3 shares · 274 followers View post →
DSHB
@DSHB_antibodies · X

Feb 17, 2025 · 7 likes · 3 shares · 2,025 followers View post →
Agingdoc
@agingdoc1 · X

The 24-hour molecular landscape after exercise in humans reveals MYC is sufficient for muscle growth https://t.co/7nmXywM2Le https://t.co/UteGx4Y700

Dec 19, 2024 · 3 likes · 41,609 followers View post →
Desi Veleva
@Desi_Veleva24 · X

The 24-hour molecular landscape after exercise in humans reveals MYC is sufficient for muscle growth | EMBO reports https://t.co/QWdl7iTicf

Dec 6, 2024 · 201 followers View post →
Muscle Cell News
@musclecellnews · X

Nov 8, 2024 · 19 likes · 4 shares · 3,191 followers View post →
Professor Adam Sharples
@DrAdamPSharples · X

RT @KevinMurachPhD: A 5+ year odyssey with @FerdinandvW “The 24-hour molecular landscape after exercise in humans reveals MYC is sufficient…

Nov 5, 2024 · 23 shares · 7,313 followers View post →
Mattia Quattrocelli
@mattiaquattro · X

The 24-hour molecular landscape after exercise in humans reveals MYC is sufficient for muscle growth https://t.co/n6qGyA5qfX of note: serial human muscle biopsies for 24hr after exercise bout; repetitive transient MYC overexpression increases soleus mass in mice

Nov 4, 2024 · 3 likes · 1,737 followers View post →
Alex
@AlexViKu · X

The 24-hour molecular landscape after exercise in humans reveals MYC is sufficient for muscle growth | EMBO reports https://t.co/2wk6uN5mkX

Nov 4, 2024 · 96 followers View post →
给你中
@wzx_7926 · X

RT @DanielJDrucker: A temporally resolved resource for understanding molecular adaptations to resistance #exercise in human muscle https://…

Nov 3, 2024 · 12 shares · 81 followers View post →
Matías Monsalves-Álvarez
@profemonsalves · X

RT @DanielJDrucker: A temporally resolved resource for understanding molecular adaptations to resistance #exercise in human muscle https://…

Nov 3, 2024 · 12 shares · 1,508 followers View post →
Samuel Montalvo, PhD, CSCS,*D., CPSS
@Dr_Montalvo_ · X

RT @DanielJDrucker: A temporally resolved resource for understanding molecular adaptations to resistance #exercise in human muscle https://…

Nov 3, 2024 · 12 shares · 476 followers View post →
Joachim Nielsen
@JoachimNielsen6 · X

RT @DanielJDrucker: A temporally resolved resource for understanding molecular adaptations to resistance #exercise in human muscle https://…

Nov 3, 2024 · 12 shares · 1,298 followers View post →
Abigail Mackey
@AbigailMackey1 · X

RT @DanielJDrucker: A temporally resolved resource for understanding molecular adaptations to resistance #exercise in human muscle https://…

Nov 3, 2024 · 12 shares · 3,708 followers View post →
Joe Gordon
@josephwgordon · X

RT @DanielJDrucker: A temporally resolved resource for understanding molecular adaptations to resistance #exercise in human muscle https://…

Nov 3, 2024 · 12 shares · 2,106 followers View post →
Nick Krontiris
@nick_krontiris · X

The 24-hour molecular landscape after exercise in humans reveals MYC is sufficient for muscle growth (open access) https://t.co/sf1GOcZK5G

Nov 3, 2024 · 1 like · 19,054 followers View post →
Kathy DelGiorno
@DelgiornoKathy · X

RT @DanielJDrucker: A temporally resolved resource for understanding molecular adaptations to resistance #exercise in human muscle https://…

Nov 2, 2024 · 12 shares · 1,899 followers View post →
Tim Kambič
@TimKambic · X

RT @DanielJDrucker: A temporally resolved resource for understanding molecular adaptations to resistance #exercise in human muscle https://…

Nov 2, 2024 · 12 shares · 232 followers View post →
Mind Your Science!
@MindYourSci · X

RT @DanielJDrucker: A temporally resolved resource for understanding molecular adaptations to resistance #exercise in human muscle https://…

Nov 2, 2024 · 12 shares · 131 followers View post →
Rx Readmore Livemore
@SopitaSirirata1 · X

RT @DanielJDrucker: A temporally resolved resource for understanding molecular adaptations to resistance #exercise in human muscle https://…

Nov 2, 2024 · 12 shares · 167 followers View post →
Mitchell Sammut
@SammutMitchell · X

RT @DanielJDrucker: A temporally resolved resource for understanding molecular adaptations to resistance #exercise in human muscle https://…

Nov 2, 2024 · 12 shares · 193 followers View post →
Shams Salah Mahdi
@ShamsPath · X

RT @DanielJDrucker: A temporally resolved resource for understanding molecular adaptations to resistance #exercise in human muscle https://…

Nov 2, 2024 · 12 shares · 1,443 followers View post →
Daniel J Drucker
@DanielJDrucker · X

A temporally resolved resource for understanding molecular adaptations to resistance #exercise in human muscle https://t.co/gJCNj6n6ry https://t.co/KWJX2kvWak

Nov 2, 2024 · 45 likes · 12 shares · 34,249 followers View post →
Chloé Yeung
@ccstorytime · X

RT @KevinMurachPhD: A 5+ year odyssey with @FerdinandvW “The 24-hour molecular landscape after exercise in humans reveals MYC is sufficient…

Nov 2, 2024 · 23 shares · 1,695 followers View post →
Matthew S. Alexander
@Matt_Muscle_Guy · X

RT @KevinMurachPhD: A 5+ year odyssey with @FerdinandvW “The 24-hour molecular landscape after exercise in humans reveals MYC is sufficient…

Nov 1, 2024 · 23 shares · 5,455 followers View post →
PJ Koopmans
@PJKoopmans · X

RT @KevinMurachPhD: A 5+ year odyssey with @FerdinandvW “The 24-hour molecular landscape after exercise in humans reveals MYC is sufficient…

Nov 1, 2024 · 23 shares · 164 followers View post →
Agingdoc
@agingdoc1 · X

The 24-hour molecular landscape after exercise in humans reveals MYC is sufficient for muscle growth https://t.co/7nmXywM2Le https://t.co/rrgODvBmok

Nov 1, 2024 · 5 likes · 41,609 followers View post →
Joe Gordon
@josephwgordon · X

RT @KevinMurachPhD: A 5+ year odyssey with @FerdinandvW “The 24-hour molecular landscape after exercise in humans reveals MYC is sufficient…

Oct 31, 2024 · 23 shares · 2,106 followers View post →
daniel varela PhD
@dr_dvarela_P4T · X

RT @KevinMurachPhD: A 5+ year odyssey with @FerdinandvW “The 24-hour molecular landscape after exercise in humans reveals MYC is sufficient…

Oct 31, 2024 · 23 shares · 920 followers View post →
André Katayama Yamada
@KatayamaYamada · X

RT @emboreports: The 24-hour molecular landscape after exercise in humans reveals MYCis sufficient for muscle growth. https://t.co/dydQymF…

Oct 31, 2024 · 3 shares · 403 followers View post →
André Katayama Yamada
@KatayamaYamada · X

RT @KevinMurachPhD: A 5+ year odyssey with @FerdinandvW “The 24-hour molecular landscape after exercise in humans reveals MYC is sufficient…

Oct 31, 2024 · 23 shares · 403 followers View post →
Sebastian Edman
@SebastianEdman · X

RT @KevinMurachPhD: A 5+ year odyssey with @FerdinandvW “The 24-hour molecular landscape after exercise in humans reveals MYC is sufficient…

Oct 31, 2024 · 23 shares · 174 followers View post →
Joshua Keller
@joshkeller10 · X

RT @KevinMurachPhD: A 5+ year odyssey with @FerdinandvW “The 24-hour molecular landscape after exercise in humans reveals MYC is sufficient…

Oct 31, 2024 · 23 shares · 942 followers View post →
Dieter
@Wuhle · X

RT @emboreports: The 24-hour molecular landscape after exercise in humans reveals MYCis sufficient for muscle growth. https://t.co/dydQymF…

Oct 31, 2024 · 3 shares · 491 followers View post →
Kirby Lab
@KirbyLab_AmsUMC · X

RT @KevinMurachPhD: A 5+ year odyssey with @FerdinandvW “The 24-hour molecular landscape after exercise in humans reveals MYC is sufficient…

Oct 31, 2024 · 23 shares · 305 followers View post →
Nathalia Le Hen
@NathaliaLeHen · X

RT @KevinMurachPhD: A 5+ year odyssey with @FerdinandvW “The 24-hour molecular landscape after exercise in humans reveals MYC is sufficient…

Oct 31, 2024 · 23 shares · 2,785 followers View post →
Nathalia Le Hen
@NathaliaLeHen · X

RT @emboreports: The 24-hour molecular landscape after exercise in humans reveals MYCis sufficient for muscle growth. https://t.co/dydQymF…

Oct 31, 2024 · 3 shares · 2,785 followers View post →
EMBO Reports
@emboreports · X

The 24-hour molecular landscape after exercise in humans reveals MYCis sufficient for muscle growth. https://t.co/dydQymFhzW https://t.co/9GbxEKK9oN https://t.co/AUVneRZmO3

Oct 31, 2024 · 5 likes · 3 shares · 15,893 followers View post →
Abigail Mackey
@AbigailMackey1 · X

RT @KevinMurachPhD: A 5+ year odyssey with @FerdinandvW “The 24-hour molecular landscape after exercise in humans reveals MYC is sufficient…

Oct 31, 2024 · 23 shares · 3,708 followers View post →
Matías Monsalves-Álvarez
@profemonsalves · X

RT @KevinMurachPhD: A 5+ year odyssey with @FerdinandvW “The 24-hour molecular landscape after exercise in humans reveals MYC is sufficient…

Oct 31, 2024 · 23 shares · 1,508 followers View post →
niclasrausch
@niclasrausch · X

RT @KevinMurachPhD: A 5+ year odyssey with @FerdinandvW “The 24-hour molecular landscape after exercise in humans reveals MYC is sufficient…

Oct 31, 2024 · 23 shares · 61 followers View post →
SeaWolff
@Wolff_C89 · X

RT @KevinMurachPhD: A 5+ year odyssey with @FerdinandvW “The 24-hour molecular landscape after exercise in humans reveals MYC is sufficient…

Oct 31, 2024 · 23 shares · 1,028 followers View post →
Rafael Casuso
@rafaelcasuso · X

RT @KevinMurachPhD: A 5+ year odyssey with @FerdinandvW “The 24-hour molecular landscape after exercise in humans reveals MYC is sufficient…

Oct 31, 2024 · 23 shares · 433 followers View post →
Lucas Tafur
@structureltp · X

RT @KevinMurachPhD: A 5+ year odyssey with @FerdinandvW “The 24-hour molecular landscape after exercise in humans reveals MYC is sufficient…

Oct 31, 2024 · 23 shares · 285 followers View post →
Fran
@Franmorena98 · X

RT @KevinMurachPhD: A 5+ year odyssey with @FerdinandvW “The 24-hour molecular landscape after exercise in humans reveals MYC is sufficient…

Oct 31, 2024 · 23 shares · 472 followers View post →
Gilles Gouspillou
@GGouspillou · X

RT @KevinMurachPhD: A 5+ year odyssey with @FerdinandvW “The 24-hour molecular landscape after exercise in humans reveals MYC is sufficient…

Oct 31, 2024 · 23 shares · 1,822 followers View post →
Lukas Moesgaard
@LukasMoesgaard · X

RT @KevinMurachPhD: A 5+ year odyssey with @FerdinandvW “The 24-hour molecular landscape after exercise in humans reveals MYC is sufficient…

Oct 31, 2024 · 23 shares · 71 followers View post →
Ildus I. Ahmetov
@SportsGenomics · X

RT @KevinMurachPhD: A 5+ year odyssey with @FerdinandvW “The 24-hour molecular landscape after exercise in humans reveals MYC is sufficient…

Oct 31, 2024 · 23 shares · 588 followers View post →
Volkan Adak
@VolkanAdak · X

RT @KevinMurachPhD: A 5+ year odyssey with @FerdinandvW “The 24-hour molecular landscape after exercise in humans reveals MYC is sufficient…

Oct 31, 2024 · 23 shares · 93 followers View post →
William Apró, PhD
@WiApro · X

RT @KevinMurachPhD: A 5+ year odyssey with @FerdinandvW “The 24-hour molecular landscape after exercise in humans reveals MYC is sufficient…

Oct 31, 2024 · 23 shares · 1,334 followers View post →
Kevin Murach
@KevinMurachPhD · X

A 5+ year odyssey with @FerdinandvW “The 24-hour molecular landscape after exercise in humans reveals MYC is sufficient for muscle growth” in @emboreports https://t.co/8gfd52FCDG Congrats to 1st authors! @SebastianEdman @RonaldGJones3 Database: https://t.co/y1hmLXWUtf #myotwitter

Oct 31, 2024 · 99 likes · 23 shares · 2,977 followers View post →