“Extracellular vesicles from human-induced pluripotent stem cell-derived neural stem cells alleviate proinflammatory cascades within disease-associated microglia in Alzheimer’s disease” by Ashok K. Shetty et al. Journal of Extracellular Vesicles https://t.co/0ah54Bm2yh
Extracellular vesicles from human-induced pluripotent stem cell-derived neural stem cells alleviate proinflammatory cascades within disease-associated microglia in Alzheimer's disease.
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Jul 2023 – Dec 2024Where it's discussed
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News52 articles
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X / Twitter13 posts
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Blogs3 articles
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YouTube2 videos
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What people are saying
Several comments emphasize the breakthrough nature of using extracellular vesicles from neural stem cells, with specific mentions of reduced neuroinflammation and cognitive improvements in mice. The tone varies from optimistic reports on potential clinical applications to detailed technical discussions, highlighting high engagement and perceived impact of this research.
Most posts agree on the therapeutic potential of extracellular vesicles in Alzheimer's treatment, highlighting their anti-inflammatory properties.
Discussions reflect high curiosity and enthusiasm, especially about the innovative method of intranasal delivery and its implications.
Posts demonstrate detailed engagement, referencing specific mechanisms like microglia modulation and mentioning notable studies or institutions.
The discussions suggest a strong belief that this research could significantly influence future Alzheimer's therapies, with terms like 'game changer' and 'promising' used frequently.
Abstract in brief
- Current Alzheimer's treatments are insufficient, highlighting the need for novel therapies that can slow disease progression and enhance brain function.
- Anti-inflammatory extracellular vesicles (EVs) derived from human induced pluripotent stem cell (hiPSC)-derived neural stem cells (NSCs) show potential as a disease-modifying option.
- In a study involving 5xFAD mice, intranasal administration of hiPSC-NSC-EVs led to beneficial changes in brain immune cells, reduced inflammation, and improved cognitive and mood function, demonstrating the EVs' lasting positive effects on Alzheimer's disease.
Top posts
Most liked on X and BlueskyIntranasally administered extracellular vesicles from human induced pluripotent stem cell-derived neural stem cells quickly incorporate into neurons and microglia in 5xFAD mice https://t.co/kgjFPKrtmX @FrontAging @FrontNeurosci https://t.co/dm5ORGcF81
RT @agingdoc1: Intranasally administered extracellular vesicles from human induced pluripotent stem cell-derived neural stem cells quickly…
RT @ISEV_Journals:
All mentions
Extracellular Vesicles from Stem Cells Offer New Alzheimer's Therapy Options
Recent scientific advances reveal that extracellular vesicles released by stem cells provide promising avenues for treating aging-related diseases like Alzheimer's by reducing inflammation and supporting brain…
Extracellular Vesicles and Stem Cells in Medical Regeneration
This video explores how small extracellular vesicles from stem cells are transforming medicine. Recent science shows these vesicles can help treat diseases like Alzheimer's and improve body rejuvenation, offering…
Extracellular vesicles from human‐induced pluripotent stem cell‐derived neural stem cells alleviate proinflammatory cascades within disease‐associated microglia in Alzheimer's disease. https://t.co/EHaog84tL1
https://t.co/XpXjDFaU6O
RT @NeuroscienceNew: “Extracellular vesicles from human-induced pluripotent stem cell-derived neural stem cells alleviate proinflammatory c…
Extracellular vesicles from human‐induced pluripotent stem cell‐derived neural stem cells alleviate proinflammatory cascades within disease‐associated microglia in Alzheimer's disease - Madhu - 2024 - Journal of Extracellular Vesicles - https://t.co/dnvC2G8Ndq
RT @ISEV_Journals:
RT @NeuroscienceNew: “Extracellular vesicles from human-induced pluripotent stem cell-derived neural stem cells alleviate proinflammatory c…
RT @NeuroscienceNew: “Extracellular vesicles from human-induced pluripotent stem cell-derived neural stem cells alleviate proinflammatory c…
RT @NeuroscienceNew: “Extracellular vesicles from human-induced pluripotent stem cell-derived neural stem cells alleviate proinflammatory c…
“Extracellular vesicles from human-induced pluripotent stem cell-derived neural stem cells alleviate proinflammatory cascades within disease-associated microglia in Alzheimer’s disease” by Ashok K. Shetty et al. Journal of Extracellular Vesicles https://t.co/0ah54Bm2yh
RT @agingdoc1: Intranasally administered extracellular vesicles from human induced pluripotent stem cell-derived neural stem cells quickly…
Intranasally administered extracellular vesicles from human induced pluripotent stem cell-derived neural stem cells quickly incorporate into neurons and microglia in 5xFAD mice https://t.co/kgjFPKrtmX @FrontAging @FrontNeurosci https://t.co/dm5ORGcF81