Un espoir pour le traitement de l’endométriose ? Le traitement des souris avec des médicaments approuvés bloquant la signalisation CGRP-RAMP1 a conduit à une réduction de la douleur et de la taille des lésions. https://t.co/dRofqvs3Ka https://t.co/GcALtheevR
Nociceptor-to-macrophage communication through CGRP/RAMP1 signaling drives endometriosis-associated pain and lesion growth in mice.
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Aug 2023 – Mar 2025Where it's discussed
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X / Twitter65 posts
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News22 articles
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Bluesky3 posts
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Facebook3 posts
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YouTube2 videos
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Blogs2 articles
AI synopsis
What people are saying
Several discussions highlight that drugs commonly used for migraines, such as CGRP antagonists, may also benefit individuals suffering from endometriosis. Phrases like 'potential treatment' and 'nonhormonal option' indicate a hopeful tone, suggesting excitement around the possibility of new therapies. The language used reflects a strong belief in the study's findings, with many contributors eager to explore the practical applications of this research.
The majority of posts express strong support for the findings and potential applications of the research.
There is significant enthusiasm and curiosity, with many comments reflecting a keen interest in the implications for treatment.
Some posts show a moderate level of engagement, mentioning the study's details but less focus on deeper discussions.
The discussions perceive the research as having a substantial impact on understanding and treating endometriosis.
Abstract in brief
- Endometriosis is a painful inflammatory disease affecting around 15% of women and transgender men, with current treatments often proving ineffective.
- Researchers explored the involvement of calcitonin gene-related peptide (CGRP) and its receptor RAMP1 in the disease, finding that both human and mouse endometriosis lesions contain these components.
- Blocking CGRP/RAMP1 signaling in a mouse model not only reduced pain and lesion size but also uncovered cellular mechanisms that could lead to effective non-hormonal treatments for endometriosis in clinical settings.
Top posts
Most liked on X and BlueskyI am happy to share that our work on endometriosis and pain has been now published on @ScienceTM https://t.co/aYL0wZUsVw https://t.co/e1hxKByJA2
#Preprint Alert
Really interesting! Nociceptor-to-macrophage communication through CGRP/RAMP1 signaling drives endometriosis-associated pain and lesion growth in mice | Science Translational Medicine https://t.co/HoUYTUOhVh
Blocking nociceptor CGRP to RAMP1 signaling in macrophages reduces endometriosis pain and lesion growth in a mouse model of the disease @ScienceTM @victor_fattori https://t.co/V3VAyOhrrW https://t.co/ctrNS8igSI
Nociceptor to macrophage communication through CGRP/RAMP1 signaling drives endometriosis-associated pain and lesion growth https://t.co/R1IztAB0gX #biorxiv_neursci
All mentions
Hope for Endometriosis: CGRP/RAMP1 Blockade Reduces Pain and Lesion Growth
New Insights into Non-Hormonal Endometriosis Treatments
A recent study published in Science Translational Medicine explores the involvement of CGRP and RAMP1 in endometriosis. Researchers found that blocking this signaling pathway reduces pain and lesion size in mice, paving…
Researchers in Boston found that CGRP-blocking drugs commonly used for #migraine may help with endometriosis pain and lesion size. Molly O’Brien has the details in this #MigraineMinute news update recognizing #Endometriosis Awareness Month. Read More: https://t.co/UFanJvGxqL https://t.co/W7vpr4PhMe
Nociceptor-to-macrophage communication through CGRP/RAMP1 signaling drives endometriosis-associated pain and lesion growth in mice "...targeting this axis may lead to clinical benefit for patients with endometriosis." https://t.co/cF5v6Iqgsn
Research suggests CGRP antagonists (migraine meds like Nurtec) may reduce pain and lesion growth by targeting the neuroimmune connection. Human studies are lacking, but if CGRP fuels pain and inflammation, modulating it could be a nonhormonal way to help. https://t.co/qGasguxnz0
RT @NYUPainResearch: CGRP/RAMP1-mediated communication between TRPV1+ nociceptors and macrophages contributes to the growth of endometriosi…
RT @NYUPainResearch: CGRP/RAMP1-mediated communication between TRPV1+ nociceptors and macrophages contributes to the growth of endometriosi…
RT @NYUPainResearch: CGRP/RAMP1-mediated communication between TRPV1+ nociceptors and macrophages contributes to the growth of endometriosi…
CGRP/RAMP1-mediated communication between TRPV1+ nociceptors and macrophages contributes to the growth of endometriosis lesions and associated pain, highlighting a potential treatment by inhibiting this pathway #Painresearch https://t.co/uRty2OvoXT
The authors demonstrated the effectiveness and underlying cellular mechanisms of nonhormonal and nonopioid CGRP/RAMP1 blockade in a mouse model of endometriosis, suggesting that targeting this axis may lead to clinical benefit for patients with endometrios https://t.co/Yp2004JaFR
RT @ScienceTM: Studying patient samples and mice, a team finds that crosstalk between nociceptors and #macrophages through the peptide CGRP…
Studying patient samples and mice, a team finds that crosstalk between nociceptors and #macrophages through the peptide CGRP worsens pain and lesion size in #endometriosis, which can be disrupted with approved drugs. @victor_fattori @BostonChildrens https://t.co/vOSlh9EX6v https://t.co/1uGt4ydEwo
RT @immunonoah: Really interesting! Nociceptor-to-macrophage communication through CGRP/RAMP1 signaling drives endometriosis-associated pai…
RT @immunonoah: Really interesting! Nociceptor-to-macrophage communication through CGRP/RAMP1 signaling drives endometriosis-associated pai…
RT @Cobra_FX_: Un espoir pour le traitement de l’endométriose ? Le traitement des souris avec des médicaments approuvés bloquant la signal…
RT @Cobra_FX_: Un espoir pour le traitement de l’endométriose ? Le traitement des souris avec des médicaments approuvés bloquant la signal…
RT @immunonoah: Really interesting! Nociceptor-to-macrophage communication through CGRP/RAMP1 signaling drives endometriosis-associated pai…
RT @Cobra_FX_: Un espoir pour le traitement de l’endométriose ? Le traitement des souris avec des médicaments approuvés bloquant la signal…
RT @Cobra_FX_: Un espoir pour le traitement de l’endométriose ? Le traitement des souris avec des médicaments approuvés bloquant la signal…
RT @Cobra_FX_: Un espoir pour le traitement de l’endométriose ? Le traitement des souris avec des médicaments approuvés bloquant la signal…
RT @Cobra_FX_: Un espoir pour le traitement de l’endométriose ? Le traitement des souris avec des médicaments approuvés bloquant la signal…
RT @Cobra_FX_: Un espoir pour le traitement de l’endométriose ? Le traitement des souris avec des médicaments approuvés bloquant la signal…
RT @Cobra_FX_: Un espoir pour le traitement de l’endométriose ? Le traitement des souris avec des médicaments approuvés bloquant la signal…
RT @Cobra_FX_: Un espoir pour le traitement de l’endométriose ? Le traitement des souris avec des médicaments approuvés bloquant la signal…
RT @Cobra_FX_: Un espoir pour le traitement de l’endométriose ? Le traitement des souris avec des médicaments approuvés bloquant la signal…
RT @immunonoah: Really interesting! Nociceptor-to-macrophage communication through CGRP/RAMP1 signaling drives endometriosis-associated pai…
RT @Cobra_FX_: Un espoir pour le traitement de l’endométriose ? Le traitement des souris avec des médicaments approuvés bloquant la signal…
RT @Cobra_FX_: Un espoir pour le traitement de l’endométriose ? Le traitement des souris avec des médicaments approuvés bloquant la signal…
RT @Cobra_FX_: Un espoir pour le traitement de l’endométriose ? Le traitement des souris avec des médicaments approuvés bloquant la signal…
RT @Cobra_FX_: Un espoir pour le traitement de l’endométriose ? Le traitement des souris avec des médicaments approuvés bloquant la signal…
RT @Cobra_FX_: Un espoir pour le traitement de l’endométriose ? Le traitement des souris avec des médicaments approuvés bloquant la signal…
Un espoir pour le traitement de l’endométriose ? Le traitement des souris avec des médicaments approuvés bloquant la signalisation CGRP-RAMP1 a conduit à une réduction de la douleur et de la taille des lésions. https://t.co/dRofqvs3Ka https://t.co/GcALtheevR
RT @immunonoah: Really interesting! Nociceptor-to-macrophage communication through CGRP/RAMP1 signaling drives endometriosis-associated pai…
RT @immunonoah: Really interesting! Nociceptor-to-macrophage communication through CGRP/RAMP1 signaling drives endometriosis-associated pai…
Really interesting! Nociceptor-to-macrophage communication through CGRP/RAMP1 signaling drives endometriosis-associated pain and lesion growth in mice | Science Translational Medicine https://t.co/HoUYTUOhVh
RT @AM_Malf: Nociceptor-to-macrophage communication through CGRP/RAMP1 signaling drives endometriosis-associated pain and lesion growth in…
Estudio que sugiere que las terapias para la migraña, también podrían ser útiles para la endometriosis. Science Translational Medicine https://t.co/JksnEjqIEr
RT @LabWaggoner: Blocking nociceptor CGRP to RAMP1 signaling in macrophages reduces endometriosis pain and lesion growth in a mouse model o…
RT @AndrewW66619812: The paper in "Science Translational Medicine" the above "Nature" article is based upon, & links to: “Nociceptor-to-ma…
The paper in "Science Translational Medicine" the above "Nature" article is based upon, & links to: “Nociceptor-to-macrophage communication through CGRP/RAMP1 signaling drives endometriosis-associated pain and lesion growth in mice” 2/2 https://t.co/ctdXIdyPgF
RT @victor_fattori: I am happy to share that our work on endometriosis and pain has been now published on @ScienceTM https://t.co/aYL0wZU…
RT @victor_fattori: I am happy to share that our work on endometriosis and pain has been now published on @ScienceTM https://t.co/aYL0wZU…
RT @victor_fattori: I am happy to share that our work on endometriosis and pain has been now published on @ScienceTM https://t.co/aYL0wZU…
RT @victor_fattori: I am happy to share that our work on endometriosis and pain has been now published on @ScienceTM https://t.co/aYL0wZU…
RT @LabWaggoner: Blocking nociceptor CGRP to RAMP1 signaling in macrophages reduces endometriosis pain and lesion growth in a mouse model o…
RT @takatoh_life: 【原著論文】 V. Fattori, et al. "Nociceptor-to-macrophage communication through CGRP/RAMP1 signaling drives endometriosis-assoc…
RT @victor_fattori: I am happy to share that our work on endometriosis and pain has been now published on @ScienceTM https://t.co/aYL0wZU…
【原著論文】 V. Fattori, et al. "Nociceptor-to-macrophage communication through CGRP/RAMP1 signaling drives endometriosis-associated pain and lesion growth in mice" Science Translational Medicine, 6 Nov 2024. Vol 16, Issue 772 www.science.org/doi/10.1126/...
【原著論文】 V. Fattori, et al. "Nociceptor-to-macrophage communication through CGRP/RAMP1 signaling drives endometriosis-associated pain and lesion growth in mice" Science Translational Medicine, 6 Nov 2024. Vol 16, Issue 772 https://t.co/OybSsVvHJc
Nociceptor-to-macrophage communication through CGRP/RAMP1 signaling drives endometriosis-associated pain and lesion growth in mice | Science Translational Medicine https://t.co/23nJoMMihd
Blocking CGRP-RAMP1 reduced pain and lesion size in a mouse model of endometriosis. This pathway, linked to nerve-immune signaling, could offer a new nonhormonal treatment option for endometriosis pain. https://t.co/VIubFVZcls
RT @LabWaggoner: Blocking nociceptor CGRP to RAMP1 signaling in macrophages reduces endometriosis pain and lesion growth in a mouse model o…
RT @LabWaggoner: Blocking nociceptor CGRP to RAMP1 signaling in macrophages reduces endometriosis pain and lesion growth in a mouse model o…
RT @LabWaggoner: Blocking nociceptor CGRP to RAMP1 signaling in macrophages reduces endometriosis pain and lesion growth in a mouse model o…
I am happy to share that our work on endometriosis and pain has been now published on @ScienceTM https://t.co/aYL0wZUsVw https://t.co/e1hxKByJA2
RT @LabWaggoner: Blocking nociceptor CGRP to RAMP1 signaling in macrophages reduces endometriosis pain and lesion growth in a mouse model o…
Blocking nociceptor CGRP to RAMP1 signaling in macrophages reduces endometriosis pain and lesion growth in a mouse model of the disease @ScienceTM @victor_fattori https://t.co/V3VAyOhrrW https://t.co/ctrNS8igSI
RT @biorxiv_neursci: Nociceptor to macrophage communication through CGRP/RAMP1 signaling drives endometriosis-associated pain and lesion gr…
RT @victor_fattori: #Preprint Alert
RT @biorxiv_neursci: Nociceptor to macrophage communication through CGRP/RAMP1 signaling drives endometriosis-associated pain and lesion gr…
RT @victor_fattori: #Preprint Alert
RT @victor_fattori: #Preprint Alert
RT @biorxiv_neursci: Nociceptor to macrophage communication through CGRP/RAMP1 signaling drives endometriosis-associated pain and lesion gr…
RT @biorxiv_neursci: Nociceptor to macrophage communication through CGRP/RAMP1 signaling drives endometriosis-associated pain and lesion gr…
Nociceptor to macrophage communication through CGRP/RAMP1 signaling drives endometriosis-associated pain and lesion growth https://t.co/DhrxbwhK5C
Nociceptor to macrophage communication through CGRP/RAMP1 signaling drives endometriosis-associated pain and lesion growth https://www.biorxiv.org/content/10.1101/2023.08.28.555101v1
Nociceptor to macrophage communication through CGRP/RAMP1 signaling drives endometriosis-associated pain and lesion growth https://www.biorxiv.org/content/10.1101/2023.08.28.555101v1
Nociceptor to macrophage communication through CGRP/RAMP1 signaling drives endometriosis-associated pain and lesion growth https://t.co/R1IztAB0gX #biorxiv_neursci
RT @victor_fattori: #Preprint Alert
#Preprint Alert