October 2024 PMID 39519498

Effects of Creatine Supplementation and Resistance Training on Muscle Strength Gains in Adults <50 Years of Age: A Systematic Review and Meta-Analysis.

Ziyu Wang, Bopeng Qiu, Ruoling Li, Yunzhi Han, Carl Petersen, Shuting Liu, Yinkai Zhang, Chang Liu, Darren G Candow, Juan Del Coso

Mentions

59
Peak: 22 in Oct 2024
across 5 sources since Apr 2019

Extended reach

287,227
potential audience

Total likes

234

Video views

372

Mentions per month

Apr 2019 – Nov 2025

Where it's discussed

  • X / Twitter48 posts
  • News5 articles
  • Reddit3 posts
  • YouTube2 videos
  • Bluesky1 posts

AI synopsis

What people are saying

The overall tone reflects both skepticism and support for creatine’s efficacy, with references to meta-analyses and scientific papers illustrating a thorough engagement with the research. Words like 'weak evidence' and 'should have linked more meta-analyses' reveal critical perspectives, while remarks like 'creatine absolutely works' show strong support, indicating a balanced but engaged discussion.

AgreementModerate agreement

Most discussions support the conclusion that creatine is effective, with some critiques questioning the strength of the evidence. For example, some posts cite meta-analyses showing positive effects, while others point out the study's small sample size.

InterestHigh interest

Posts show a high level of interest, with commenters referencing specific studies, meta-analyses, and scientific sources, indicating engagement with detailed research.

EngagementModerate engagement

Many discussions delve into the nuances of the research, debating the strength of evidence and practical implications, demonstrating moderate depth.

ImpactModerate impact

The discussions highlight that the publication reinforces existing beliefs about creatine's effectiveness, potentially influencing personal supplementation choices and scientific understanding in the community.

Top posts

Most liked on X and Bluesky
Darren Candow, PhD, CSEP-CEP, FISSN
@darrencandow · X

Effects of Creatine Supplementation and Resistance Training on Muscle Strength Gains in Adults < 50 years of age: A Systematic Review and Meta-Analysis #creatine https://t.co/MylSTKIkSh

Oct 29, 2024 · 94 likes · 23 shares · 6,728 followers View post →
Daniel Berglind, PhD
@DanielBerglind · X

Meta-analysis: creatine supplementation

Nov 3, 2024 · 80 likes · 14 shares · 7,849 followers View post →
Johnny
@biojohnny5 · X

@ClarkAbent https://t.co/Xw3CsbIT8z https://t.co/1xQC848teJ Creatine absolutely works, it’s one of the most studied and proven supplements out there. That said, if someone eats a lot of red meat, their muscles might already be close to saturated with creatine naturally. But most people

Mar 28, 2025 · 15 likes · 8,372 followers View post →
Laurenz Markula
@tweetATlaurenz · X

@SimgeBnl @elvin42x @whyz_khalifa Rawson ES,Volek JS. Effects of creatine supplementation and resistance training on muscle strength and weightlifting performance. J Strength Cond Res. 2003 Nov;17(4):822-31. doi:10.1519/1533-4287(2003)017<0822:eocsar>https://t.co/ryqAIMqhJb;2. PMID: 14636102. Hört sich positiv an

Jan 17, 2023 · 13 likes · 26 followers View post →
Nick Krontiris
@nick_krontiris · X

Effects of Creatine Supplementation and Resistance Training on Muscle Strength Gains in Adults < 50 Years of Age: A Systematic Review and Meta-Analysis (open access) https://t.co/nPkv0veVwm

Nov 2, 2024 · 4 likes · 19,384 followers View post →
4nt1p4tt3rn
@4nt1p4tt3rn · X

@DegenBiWeeb @Master2udarnit https://t.co/kqwAtDz4mF https://t.co/WLi5xRFEe1

Aug 20, 2025 · 3 likes · 22,624 followers View post →

All mentions

Altu Kop
@AltuKop · X

@DeathlyHarvest @warrioraspie @BioLayne Lmao. Your one study of 53 people showed no effect Vs the hundreds of studies and meta-analysis' that show the opposite..

Sep 4, 2025 · 1 like · 3,800 followers View post →
4nt1p4tt3rn
@4nt1p4tt3rn · X

@DegenBiWeeb @Master2udarnit https://t.co/kqwAtDz4mF https://t.co/WLi5xRFEe1

Aug 20, 2025 · 3 likes · 22,624 followers View post →
snus&hustle ⵣ
@snusetwesson · X

@darkironLyon @inesss_1212 ChatGPT : Karting Essais randomisés et Meta analyses : F1 => Ccl : + d’hypertrophie, de force, d’endurance musculaire Pour la énième fois lache moi la grappe t’as pas le niveau brf bonne lecture t’apprendras plus qu’avec une IA https://t.co/ik4EZ3cxQC https://t.co/X0vU8NPkCI

Jun 8, 2025 · 224 followers View post →
Caleb Mahlen
@cmahlen.bsky.social · Bluesky

I agree that the evidence cited in the article was weak. Instead, they should have linked one of the several meta analyses or systematic reviews showing that creatine improves strength in general and in a number of specific populations. Like this one for example pubmed.ncbi.nlm.nih.gov/39519498/

May 14, 2025 · 2 likes · 1 share View post →
Neosapien
@NeoSapien_ · X

Cognition & Supplementation Study: https://t.co/EmCnIiAGvg Picture for Stroop test: By Unreferierbar - Own work, CC0, https://t.co/4GYSbQXO6l

Apr 25, 2025 · 1 followers View post →
Johnny
@biojohnny5 · X

@ClarkAbent https://t.co/Xw3CsbIT8z https://t.co/1xQC848teJ Creatine absolutely works, it’s one of the most studied and proven supplements out there. That said, if someone eats a lot of red meat, their muscles might already be close to saturated with creatine naturally. But most people

Mar 28, 2025 · 15 likes · 8,372 followers View post →
MartycFly.base.eth |
@Marty_cFly · X

@offerdaling @yacineMTB Yes. Google's medical trained AI. Gpt you can also ask for pubmed sources. Just check those. Random example: How does creatine affect health. Use latest pubmed https://t.co/Gqgm2MXysN https://t.co/uCyQj8Q7nO

Jan 13, 2025 · 1 like · 12,425 followers View post →
Bader alshatti Ms
@alshatti_fit · X

المصدر: https://t.co/9OllF8ziG9

Dec 26, 2024 · 1 like · 9,855 followers View post →
Orlando_uy
@Orlando_uy · X

Effects of Creatine Supplementation and Resistance Training on Muscle Strength Gains in Adults <50 Years of Age: Review and Meta-Analysis Creatine supplementation combined with resistance training significantly increased upper-body and lower-body strength. https://t.co/L9o1PxabVf

Nov 29, 2024 · 1 like · 695 followers View post →
Tom Coughlin
@tecoughlin · X

Reference: https://t.co/dUhrLkxZpP

Nov 7, 2024 · 3 likes · 4,255 followers View post →
ScienceCritAI
@ScienceCrit_AI · X

Curious for more?

Nov 4, 2024 · 17 followers View post →
stephen LoRusso
@stephenLoRusso2 · X

RT @DanielBerglind: Meta-analysis: creatine supplementation

Nov 3, 2024 · 14 shares · 208 followers View post →
Diane Buchta
@BuchtaDiane · X

RT @DanielBerglind: Meta-analysis: creatine supplementation

Nov 3, 2024 · 14 shares · 277 followers View post →
Kristopher Mendes de Souza
@KristopherDoc · X

RT @DanielBerglind: Meta-analysis: creatine supplementation

Nov 3, 2024 · 14 shares · 66 followers View post →
Gregory Miller, Ph.D.
@drdairy50 · X

RT @DanielBerglind: Meta-analysis: creatine supplementation

Nov 3, 2024 · 14 shares · 10,740 followers View post →
Colleen Griffith
@Griffith17431 · X

RT @DanielBerglind: Meta-analysis: creatine supplementation

Nov 3, 2024 · 14 shares · 937 followers View post →
Koushik
@koushikphysio · X

RT @DanielBerglind: Meta-analysis: creatine supplementation

Nov 3, 2024 · 14 shares · 523 followers View post →
Missael
@miiss_ael · X

RT @DanielBerglind: Meta-analysis: creatine supplementation

Nov 3, 2024 · 14 shares · 90 followers View post →
Mind Your Science!
@MindYourSci · X

RT @DanielBerglind: Meta-analysis: creatine supplementation

Nov 3, 2024 · 14 shares · 132 followers View post →
Argón
@metilargon · X

RT @DanielBerglind: Meta-analysis: creatine supplementation

Nov 3, 2024 · 14 shares · 352 followers View post →
Zack
@keychupkicap · X

RT @DanielBerglind: Meta-analysis: creatine supplementation

Nov 3, 2024 · 14 shares · 389 followers View post →
Carlos Alberto
@CarlosAbertoVM · X

RT @DanielBerglind: Meta-analysis: creatine supplementation

Nov 3, 2024 · 14 shares · 142 followers View post →
Daniel Berglind, PhD
@DanielBerglind · X

Meta-analysis: creatine supplementation

Nov 3, 2024 · 80 likes · 14 shares · 7,849 followers View post →
Nick Krontiris
@nick_krontiris · X

Effects of Creatine Supplementation and Resistance Training on Muscle Strength Gains in Adults < 50 Years of Age: A Systematic Review and Meta-Analysis (open access) https://t.co/nPkv0veVwm

Nov 2, 2024 · 4 likes · 19,384 followers View post →
YURI PAUCAR
@ypaucar · X

RT @darrencandow: Effects of Creatine Supplementation and Resistance Training on Muscle Strength Gains in Adults < 50 years of age: A Syst…

Oct 30, 2024 · 23 shares · 1,209 followers View post →
Diane Buchta
@BuchtaDiane · X

RT @darrencandow: Effects of Creatine Supplementation and Resistance Training on Muscle Strength Gains in Adults < 50 years of age: A Syst…

Oct 30, 2024 · 23 shares · 277 followers View post →
Mind Your Science!
@MindYourSci · X

RT @darrencandow: Effects of Creatine Supplementation and Resistance Training on Muscle Strength Gains in Adults < 50 years of age: A Syst…

Oct 30, 2024 · 23 shares · 132 followers View post →
Thomas
@gireviktmac619 · X

RT @darrencandow: Effects of Creatine Supplementation and Resistance Training on Muscle Strength Gains in Adults < 50 years of age: A Syst…

Oct 30, 2024 · 23 shares · 191 followers View post →
Missael
@miiss_ael · X

RT @darrencandow: Effects of Creatine Supplementation and Resistance Training on Muscle Strength Gains in Adults < 50 years of age: A Syst…

Oct 30, 2024 · 23 shares · 90 followers View post →
Wilhelm Beermann
@WilhelmBeermann · X

RT @darrencandow: Effects of Creatine Supplementation and Resistance Training on Muscle Strength Gains in Adults < 50 years of age: A Syst…

Oct 30, 2024 · 23 shares · 128 followers View post →
Nick Krontiris
@nick_krontiris · X

RT @darrencandow: Effects of Creatine Supplementation and Resistance Training on Muscle Strength Gains in Adults < 50 years of age: A Syst…

Oct 30, 2024 · 23 shares · 19,384 followers View post →
Cláudia
@claudianutri · X

RT @darrencandow: Effects of Creatine Supplementation and Resistance Training on Muscle Strength Gains in Adults < 50 years of age: A Syst…

Oct 29, 2024 · 23 shares · 137 followers View post →
Scott Forbes
@DrCreatine · X

RT @darrencandow: Effects of Creatine Supplementation and Resistance Training on Muscle Strength Gains in Adults < 50 years of age: A Syst…

Oct 29, 2024 · 23 shares · 835 followers View post →
Jay Bert
@bert695 · X

RT @darrencandow: Effects of Creatine Supplementation and Resistance Training on Muscle Strength Gains in Adults < 50 years of age: A Syst…

Oct 29, 2024 · 23 shares · 873 followers View post →
Zack
@keychupkicap · X

RT @darrencandow: Effects of Creatine Supplementation and Resistance Training on Muscle Strength Gains in Adults < 50 years of age: A Syst…

Oct 29, 2024 · 23 shares · 389 followers View post →
Ellie Jones
@_ELLIE_JONES_x · X

RT @darrencandow: Effects of Creatine Supplementation and Resistance Training on Muscle Strength Gains in Adults < 50 years of age: A Syst…

Oct 29, 2024 · 23 shares · 754 followers View post →
Longevity
@Longevity_ESPM · X

RT @darrencandow: Effects of Creatine Supplementation and Resistance Training on Muscle Strength Gains in Adults < 50 years of age: A Syst…

Oct 29, 2024 · 23 shares · 728 followers View post →
David_Propst_PA-C
@PrimaryCarePAC · X

RT @darrencandow: Effects of Creatine Supplementation and Resistance Training on Muscle Strength Gains in Adults < 50 years of age: A Syst…

Oct 29, 2024 · 23 shares · 3,334 followers View post →
Jose Antonio PhD
@JoseAntonioPhD · X

RT @darrencandow: Effects of Creatine Supplementation and Resistance Training on Muscle Strength Gains in Adults < 50 years of age: A Syst…

Oct 29, 2024 · 23 shares · 22,203 followers View post →
Gregory Miller, Ph.D.
@drdairy50 · X

RT @darrencandow: Effects of Creatine Supplementation and Resistance Training on Muscle Strength Gains in Adults < 50 years of age: A Syst…

Oct 29, 2024 · 23 shares · 10,740 followers View post →
@Ap_Coach Amedio
@ap_coach · X

RT @darrencandow: Effects of Creatine Supplementation and Resistance Training on Muscle Strength Gains in Adults < 50 years of age: A Syst…

Oct 29, 2024 · 23 shares · 1,405 followers View post →
Fit For Golf - Mike Carroll
@Fit_For_Golf · X

RT @darrencandow: Effects of Creatine Supplementation and Resistance Training on Muscle Strength Gains in Adults < 50 years of age: A Syst…

Oct 29, 2024 · 23 shares · 105,753 followers View post →
Kim Tirapelle,MS,RD,CSSD
@KimTirapelleRD · X

RT @darrencandow: Effects of Creatine Supplementation and Resistance Training on Muscle Strength Gains in Adults < 50 years of age: A Syst…

Oct 29, 2024 · 23 shares · 2,452 followers View post →
Dr Chris Kirk
@ChrisKirk_ASP · X

RT @darrencandow: Effects of Creatine Supplementation and Resistance Training on Muscle Strength Gains in Adults < 50 years of age: A Syst…

Oct 29, 2024 · 23 shares · 2,780 followers View post →
Darren Candow, PhD, CSEP-CEP, FISSN
@darrencandow · X

Effects of Creatine Supplementation and Resistance Training on Muscle Strength Gains in Adults < 50 years of age: A Systematic Review and Meta-Analysis #creatine https://t.co/MylSTKIkSh

Oct 29, 2024 · 94 likes · 23 shares · 6,728 followers View post →
Latest Nutrition News
@NutritionAlerts · X

Just published in Nutrients: "Nutrients, Vol. 16, Pages 3665: Effects of Creatine Supplementation and Resistance Training on Muscle Strength Gains in Adults &lt; 50 Years of Age: A Systematic Review and Meta-Analysis". https://t.co/qZFPiAIiC2

Oct 28, 2024 · 494 followers View post →
Hubert Deep Work
@Hub_Deep_Work · X

@arthurdebons Rawson, Eric S., and Jeff S. Volek. "Effects of creatine supplementation and resistance training on muscle strength and weightlifting performance." Journal of Strength and Conditioning Research 17.4 (2003): 822-831.

Oct 8, 2023 · 1 like · 848 followers View post →
Laurenz Markula
@tweetATlaurenz · X

@SimgeBnl @elvin42x @whyz_khalifa Rawson ES,Volek JS. Effects of creatine supplementation and resistance training on muscle strength and weightlifting performance. J Strength Cond Res. 2003 Nov;17(4):822-31. doi:10.1519/1533-4287(2003)017<0822:eocsar>https://t.co/ryqAIMqhJb;2. PMID: 14636102. Hört sich positiv an

Jan 17, 2023 · 13 likes · 26 followers View post →
Fit Performance
@FitPerformUK · X

**Study Sunday** A paper published by Eric S Rawson and Jeff S Volek titled “Effects of creatine supplementation and resistance training on muscle strength and… https://t.co/lo4icnuiL7

Apr 21, 2019 · 304 followers View post →