Online now: PD-1 blockade plus cisplatin-based chemotherapy in patients with small cell/neuroendocrine bladder and prostate cancers https://t.co/fwDCOcf5uS
PD-1 blockade plus cisplatin-based chemotherapy in patients with small cell/neuroendocrine bladder and prostate cancers.
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Nov 2024 – Dec 2024Where it's discussed
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News14 articles
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X / Twitter3 posts
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Blogs3 articles
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YouTube1 videos
AI synopsis
What people are saying
Discussions reflect a balanced view, with some comments noting the promising two-year survival rates and tolerability, using phrases like 'potential breakthrough' or 'hopeful developments,' while others simply acknowledge the publication without deep elaboration. The tone varies from cautious optimism to mild interest, which aligns with the moderate scores assigned.
Most discussions recognize the promising response rates and manageable toxicity, indicating general agreement with the positive implications of the study.
Comments show a moderate level of curiosity, with some users highlighting the relevance of the treatment for rare cancers but not expressing deep passion.
Posts tend to briefly acknowledge the study's findings without detailed analysis, reflecting a neutral level of engagement.
Participants suggest the research could influence future treatment options, but the overall tone remains cautious, indicating perceived moderate impact.
Abstract in brief
- Small cell neuroendocrine cancers show similar characteristics across different tissues, often responding briefly to chemotherapy before rapidly worsening.
- A phase 1b study tested pembrolizumab combined with platinum-based chemotherapy in 15 patients, showing an overall response rate of 43% and a promising two-year overall survival rate of 86% for small cell bladder cancer and 57% for small cell prostate cancer.
- The treatment was generally well-tolerated, with 40% of patients experiencing severe side effects but no fatalities or treatment stoppages due to toxicity, alongside evidence of enhanced T cell activity linked to better outcomes.
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Most liked on X and BlueskyOnline now: PD-1 blockade plus cisplatin-based chemotherapy in patients with small cell/neuroendocrine bladder and prostate cancers https://t.co/O5Tw51WVgz
All mentions
Advancements in Cancer Therapy: Immunotherapy and Chemotherapy Combination
A breakthrough in cancer treatment is here. Combining immunotherapy with chemotherapy researchers are making significant strides in treating aggressive small cell cancers in the bladder and prostate.
RT @CellRepMed: Online now: PD-1 blockade plus cisplatin-based chemotherapy in patients with small cell/neuroendocrine bladder and prostate…
Online now: PD-1 blockade plus cisplatin-based chemotherapy in patients with small cell/neuroendocrine bladder and prostate cancers https://t.co/fwDCOcf5uS
Online now: PD-1 blockade plus cisplatin-based chemotherapy in patients with small cell/neuroendocrine bladder and prostate cancers https://t.co/O5Tw51WVgz