Nat Aging December 2024 PMID 39548320

Effect of nicotinamide riboside on airway inflammation in COPD: a randomized, placebo-controlled trial.

Kristoffer L Norheim, Michael Ben Ezra, Indra Heckenbach, Louise Munkholm Andreasson, Lise Lotte Eriksen, Nanna Dyhre-Petersen, Mads Vargas Damgaard, Magnus Berglind, Luca Pricolo, Dayle Sampson, Ryan W Dellinger, Asger Sverrild, Jonas T Treebak, Sisse Bolm Ditlev, Celeste Porsbjerg

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Mentions

35
Peak: 6 in Nov 2024
across 5 sources since Nov 2024

Extended reach

87,615
potential audience

Total likes

52

Video views

594

Mentions per month

Nov 2024 – Dec 2024

Where it's discussed

  • News18 articles
  • X / Twitter9 posts
  • Reddit3 posts
  • Blogs3 articles
  • YouTube2 videos

AI synopsis

What people are saying

The overall tone shows strong support and interest, with phrases like 'groundbreaking study' and 'new hope for COPD treatment,' emphasizing excitement around the research. Posts reference specific results, such as reduction in airway inflammation and increased NAD+ levels, which demonstrate a focus on scientific details and potential implications, reflecting a moderate but meaningful level of engagement and perceived impact.

AgreementModerate agreement

Most discussions highlight the positive findings of the study, suggesting a general consensus of agreement with the potential benefits of nicotinamide riboside (NR) for COPD inflammation reduction.

InterestHigh interest

The exploration of NR as a new treatment avenue and mentions of 'groundbreaking' findings indicate high interest among participants.

EngagementModerate engagement

Many posts share detailed summaries or highlight the significance of the study, implying a moderate level of engagement and curiosity.

ImpactModerate impact

While the findings are seen as promising, the discussions mainly focus on potential and preliminary results rather than definitive clinical impact.

Abstract in brief

  • COPD is a chronic, progressive lung disease primarily caused by smoking and aging, making it a top cause of death globally.
  • A clinical trial involving 40 stable COPD patients tested the effects of the NAD precursor nicotinamide riboside (NR) for 6 weeks, revealing a significant reduction in sputum interleukin-8 (IL-8) levels.
  • Results showed that NR not only decreased IL-8 significantly during treatment, but this positive effect lasted up to 12 weeks post-treatment, while also increasing NAD levels in the blood and indicating potential benefits for airway genomic integrity and reduced cellular aging.

Top posts

Most liked on X and Bluesky
Agingdoc
@agingdoc1 · X

Effect of nicotinamide riboside on airway inflammation in COPD: a randomized, placebo-controlled trial “Our study demonstrates that supplementation with NR reduced airway inflammation and increased NAD+ levels in whole blood…” @ScheibyeKnudsen https://t.co/nIIFbZM229 https://t.co/9VRiU7vClp

Nov 15, 2024 · 23 likes · 2 shares · 41,381 followers View post →
Kelly A. Hogan Ph.D.
@Loose_Lab_Rat · X

Effect of nicotinamide riboside on airway inflammation in COPD: a randomized, placebo-controlled trial https://t.co/ESQuPmLZWb

Dec 28, 2024 · 1 like · 2,241 followers View post →
Orlando_uy
@Orlando_uy · X

Effect of nicotinamide riboside on airway inflammation in COPD: a randomized, placebo-controlled trial. Nicotinamide riboside shows that it has anti-inflammatory effects. This is the most consistent effect of NR supplementation. https://t.co/ZK8zbEjE3e

Nov 29, 2024 · 1 like · 692 followers View post →
Agingdoc
@agingdoc1 · X

RT @agingdoc1: Effect of nicotinamide riboside on airway inflammation in COPD: a randomized, placebo-controlled trial “Our study demonstra…

Nov 29, 2024 · 2 shares · 41,381 followers View post →
TimePie (focus on anti-aging science)
@TimePieChina · X

New Advances in NR Anti-Inflammatory Activity? This study on Nature Aging shows that #NR reduces airway inflammation in COPD. By Kristoffer L. Norheim, Celeste Porsbjerg et al. https://t.co/M59GWTqxu1 https://t.co/ximaxuhoQP

Nov 18, 2024 · 691 followers View post →
Genç İVEK
@gencivek · X

4.B3 Vitaminiyle KOAH’ a Yeni Umut Kaynak: DOI: 10.1038/s43587-024-00758-1 5.Uyku Beyni Nasıl Güçlendiriyor? Yeni Araştırma Sırlarını Ortaya Çıkardı! Kaynak: https://t.co/hul5g9gKao #gencivek #bilimdebuhafta

Nov 24, 2024 · 356 followers View post →

All mentions

Ralph Turchiano
@RalphTurchiano · X

Is Nicotinamide Riboside the Future of COPD Treatment? Ep. 1221 DEC 24 https://t.co/FNvRpIfAAD via @YouTube

Dec 29, 2024 · 128 followers View post →
Kelly A. Hogan Ph.D.
@Loose_Lab_Rat · X

Effect of nicotinamide riboside on airway inflammation in COPD: a randomized, placebo-controlled trial https://t.co/ESQuPmLZWb

Dec 28, 2024 · 1 like · 2,241 followers View post →
Ralph Turchiano
@RalphTurchiano · X

Is Nicotinamide Riboside the Future of COPD Treatment? #trailer https://t.co/hmKCglkFar via @YouTube In a groundbreaking study, researchers explored the potential of high-dose vitamin B3 to combat inflammation in COPD. The study involved 40 COPD patients who were given eithe

Dec 20, 2024 · 128 followers View post →
Orlando_uy
@Orlando_uy · X

Effect of nicotinamide riboside on airway inflammation in COPD: a randomized, placebo-controlled trial. Nicotinamide riboside shows that it has anti-inflammatory effects. This is the most consistent effect of NR supplementation. https://t.co/ZK8zbEjE3e

Nov 29, 2024 · 1 like · 692 followers View post →
Agingdoc
@agingdoc1 · X

RT @agingdoc1: Effect of nicotinamide riboside on airway inflammation in COPD: a randomized, placebo-controlled trial “Our study demonstra…

Nov 29, 2024 · 2 shares · 41,381 followers View post →
Genç İVEK
@gencivek · X

4.B3 Vitaminiyle KOAH’ a Yeni Umut Kaynak: DOI: 10.1038/s43587-024-00758-1 5.Uyku Beyni Nasıl Güçlendiriyor? Yeni Araştırma Sırlarını Ortaya Çıkardı! Kaynak: https://t.co/hul5g9gKao #gencivek #bilimdebuhafta

Nov 24, 2024 · 356 followers View post →
TimePie (focus on anti-aging science)
@TimePieChina · X

New Advances in NR Anti-Inflammatory Activity? This study on Nature Aging shows that #NR reduces airway inflammation in COPD. By Kristoffer L. Norheim, Celeste Porsbjerg et al. https://t.co/M59GWTqxu1 https://t.co/ximaxuhoQP

Nov 18, 2024 · 691 followers View post →
Aging Papers
@PapersAging · X

Effect of nicotinamide riboside on airway inflammation in COPD: a randomized, placebo-controlled trial https://t.co/Oc7LIuJWPT

Nov 16, 2024 · 16 followers View post →
Agingdoc
@agingdoc1 · X

Effect of nicotinamide riboside on airway inflammation in COPD: a randomized, placebo-controlled trial “Our study demonstrates that supplementation with NR reduced airway inflammation and increased NAD+ levels in whole blood…” @ScheibyeKnudsen https://t.co/nIIFbZM229 https://t.co/9VRiU7vClp

Nov 15, 2024 · 23 likes · 2 shares · 41,381 followers View post →