In severely injured trauma patients, an early restrictive oxygen strategy vs a liberal oxygen strategy did not reduce mortality and/or major respiratory complications. #CCRdownunder @CritCareReviews https://t.co/faAf7S63Ok https://t.co/EpxYCbzIU6
Early Restrictive vs Liberal Oxygen for Trauma Patients: The TRAUMOX2 Randomized Clinical Trial.
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Jul 2024 – Jul 2025Where it's discussed
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What people are saying
The discussions show a consensus that the TRAUMOX2 trial found no benefit of restrictive oxygen strategies, with posts emphasizing the role of these findings in shaping trauma management, highlighted through phrases like 'no significant advantage' and 'may influence guidelines.' The tone varies from analytical to cautiously optimistic, illustrating both a scientific and practical engagement with the research’s implications.
Most discussions reflect acceptance of the study findings, emphasizing that restricting oxygen does not significantly impact mortality or respiratory complications.
Posts demonstrate high curiosity, highlighting the importance of oxygen strategies and referencing the broad implications for trauma care.
Many comments critically analyze the research methodology, compare with other studies, or discuss clinical practice implications, indicating deep engagement.
The discussions reference significant aspects like ethical principles and practice changes, suggesting these findings could influence future clinical guidelines.
Abstract in brief
- Early oxygen administration is crucial for severely injured trauma patients, but too much oxygen may lead to higher mortality and respiratory issues.
- The study aimed to compare a restrictive oxygen strategy (keeping oxygen saturation around 94%) to a liberal strategy (providing high levels of oxygen) in adult trauma patients to see if it would reduce death and major respiratory complications.
- The trial involved nearly 2000 patients, assigning them to one of the two strategies, and it found that outcomes for death and major respiratory complications were similar in both groups within 30 days.
Top posts
Most liked on X and BlueskyUna estrategia restrictiva de oxigenación (SpO2 94% con FiO2 promedio de 28%) es suficiente para mantener a los pacientes con Traumatismo Severo
Las Cánulas Nasales de Alto Flujo demostraron ser No-Inferiores a la Ventilación No-Invasiva en múltiples causas de Falla Respiratoria Aguda:
In severely injured trauma patients, an early restrictive oxygen strategy vs a liberal oxygen strategy did not significantly reduce mortality and/or major respiratory complications. https://t.co/DvmSf6Me1l https://t.co/VgtjPguIrh
外傷初期診療では、実証的な根拠がないまま必要量を超える酸素投与が推奨されてきた。それをテストしたランダム化比較試験 TRAUMOX2。 https://t.co/P0czcOyNwo
Early Restrictive vs Liberal Oxygen for Trauma Patients: The #TRAUMOX2 Randomized Clinical Trial | @JAMA_current Just published! #ccrdownunder https://t.co/zrZOELrSkD
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RT @emergmedottawa: Early Restrictive vs Liberal O2 for Trauma Patients: The TRAUMOX2 Randomized Clinical Trial via @JAMA_current Interpre…
RT @emergmedottawa: Early Restrictive vs Liberal O2 for Trauma Patients: The TRAUMOX2 Randomized Clinical Trial via @JAMA_current Interpre…
RT @emergmedottawa: Early Restrictive vs Liberal O2 for Trauma Patients: The TRAUMOX2 Randomized Clinical Trial via @JAMA_current Interpre…
RT @emergmedottawa: Early Restrictive vs Liberal O2 for Trauma Patients: The TRAUMOX2 Randomized Clinical Trial via @JAMA_current Interpre…
RT @emergmedottawa: Early Restrictive vs Liberal O2 for Trauma Patients: The TRAUMOX2 Randomized Clinical Trial via @JAMA_current Interpre…
Early Restrictive vs Liberal O2 for Trauma Patients: The TRAUMOX2 Randomized Clinical Trial via @JAMA_current Interpretation: There is no reason to restrict oxygen in initial management of trauma patients. https://t.co/VCaaaJeG8U https://t.co/RlpUk72okg
RT @FlightDocKosuke: JAMAより,重傷外傷において制限的酸素投与戦略は有効か?についての多施設RCT(n=1508). 成人の外傷患者(ISS:14)を最初の8時間,制限的酸素戦略(目標SpO2:94%)と自由酸素戦略(O2:12-15L/min,またはF…
RT @IcuCast: #59! We talk about TRAUMAOX2 (@JAMA_current), SAHARA (@NEJM), and answer some listener questions finishing our #ccrdownunder c…
#59! We talk about TRAUMAOX2 (@JAMA_current), SAHARA (@NEJM), and answer some listener questions finishing our #ccrdownunder coverage. Great discussions! TRAUMOX2: https://t.co/7vCDBcvZ2J SAHARA: https://t.co/mdhM0YRgRv
Early restrictive oxygen treatment for trauma patients showed no significant advantage over liberal oxygen in reducing death or complications. by Arleth T, Baekgaard J (...) Steinmetz J et 28 al. in JAMA https://t.co/KAIdbuGIHy #MedX #MedResearch
RT @JAMA_current: In severely injured trauma patients, an early restrictive oxygen strategy vs a liberal oxygen strategy did not significan…
RT @JAMA_current: In severely injured trauma patients, an early restrictive oxygen strategy vs a liberal oxygen strategy did not significan…
RT @JAMA_current: In severely injured trauma patients, an early restrictive oxygen strategy vs a liberal oxygen strategy did not significan…
RT @JAMA_current: In severely injured trauma patients, an early restrictive oxygen strategy vs a liberal oxygen strategy did not significan…
RT @JAMA_current: In severely injured trauma patients, an early restrictive oxygen strategy vs a liberal oxygen strategy did not significan…
RT @JAMA_current: In severely injured trauma patients, an early restrictive oxygen strategy vs a liberal oxygen strategy did not significan…
In severely injured trauma patients, an early restrictive oxygen strategy vs a liberal oxygen strategy did not significantly reduce mortality and/or major respiratory complications. https://t.co/DvmSf6Me1l https://t.co/VgtjPguIrh
“Early Restrictive vs Liberal Oxygen for Trauma Patients The TRAUMOX2 Randomized Clinical Trial.” Publié ce jour dans @jama.com. #Medsky jamanetwork.com/journals/jam...
Early Restrictive vs Liberal Oxygen for Trauma Patients https://t.co/bY2RON9KDD
https://t.co/4RQm6WnF4F Arleth, Tobias et al. “Early Restrictive vs Liberal Oxygen for Trauma Patients: The TRAUMOX2 Randomized Clinical Trial.” JAMA, 10.1001/jama.2024.25786. 10 Dec. 2024, doi:10.1001/jama.2024.25786 #Trauma #oxygen #emergencymedicine
Useful information @organicbotanic https://t.co/RBhhHIYZMo
RT @vm_aventho: Las Cánulas Nasales de Alto Flujo demostraron ser No-Inferiores a la Ventilación No-Invasiva en múltiples causas de Falla R…
Thank you to our very own Darla Fink, MD for presenting at our Pediatric Journal Club. Darla is a Third-Year Pediatric Critical Care Fellow. She presented: Early Restrictive vs Liberal Oxygen for Trauma Patients, The TRAUMOX2 Randomized Clinical Trial. https://t.co/u5VJ5Qo3xl
RT @FlightDocKosuke: JAMAより,重傷外傷において制限的酸素投与戦略は有効か?についての多施設RCT(n=1508). 成人の外傷患者(ISS:14)を最初の8時間,制限的酸素戦略(目標SpO2:94%)と自由酸素戦略(O2:12-15L/min,またはF…
JAMAより,重傷外傷において制限的酸素投与戦略は有効か?についての多施設RCT(n=1508). 成人の外傷患者(ISS:14)を最初の8時間,制限的酸素戦略(目標SpO2:94%)と自由酸素戦略(O2:12-15L/min,またはFiO2:0.6-1.0)に割付. 30日死亡and/or重大な呼吸器合併症は両群で差は認めず. https://t.co/mfm8JBXdNS
@MarcusSaemann will discuss this study tonight at https://t.co/T65zWM0jcq https://t.co/T65zWM0jcq https://t.co/v2IhVREhB3
RT @gunnar_heine: Heute 19:15 Teil 1 der @MarkusAtHome Top 12 Nephro https://t.co/D8fqASwEOb Partner ÖGN @dgfn_ev @com_SFNDT Gäste Timot…
Heute 19:15 Teil 1 der @MarkusAtHome Top 12 Nephro https://t.co/D8fqASwEOb Partner ÖGN @dgfn_ev @com_SFNDT Gäste Timotheus Speer, Matthias Girndt, Mariam Abu Tair Hosts @sara___helena @AKronbichler @MarcusSaemann @AntMarlies Carolin Schneppe Insa Emrich
And here comes our link for tomorrow: https://t.co/pp0foYIR7v
Paper #4: Early Restrictive vs Liberal Oxygen for Trauma Patients: The TRAUMOX2 Randomized Clinical Trial, Arleth et al, JAMA Question: Does a restrictive versus liberal strategy during the first 8 hours after major trauma affect mortality or respiratory complications? Lesson
Paper #4: Early Restrictive vs Liberal Oxygen for Trauma Patients: The TRAUMOX2 Randomized Clinical Trial, Arleth et al, JAMA Question: Does a restrictive versus liberal strategy during the first 8 hours after major trauma affect mortality or respiratory complications? Lesson
RT @vm_aventho: Las Cánulas Nasales de Alto Flujo demostraron ser No-Inferiores a la Ventilación No-Invasiva en múltiples causas de Falla R…
A restrictive oxygen strategy did not significantly decrease death or respiratory complications in severely injured trauma patients compared to a liberal approach. by Arleth T, Baekgaard J (...) Steinmetz J et 28 al. in JAMA https://t.co/KAIdbuHgx6 #MedX #MedResearch
重症外傷の酸素投与はSpO2 94%以上目標で酸素増減するか、12-15L酸素投与とするかで30日以内の死亡および/または主要な呼吸器合併症の複合アウトカムを比較し有意差なしと。とりあえず酸素全開!は不要かも? https://t.co/ptqxbKP10q
RT @YodaCCP: Interesting considering how we work so hard to bring down FiO2 in our ventilated patients. https://t.co/ikjP0LXIml https://t…
RT @YodaCCP: Interesting considering how we work so hard to bring down FiO2 in our ventilated patients. https://t.co/ikjP0LXIml https://t…
RT @YodaCCP: Interesting considering how we work so hard to bring down FiO2 in our ventilated patients. https://t.co/ikjP0LXIml https://t…
RT @vm_aventho: Las Cánulas Nasales de Alto Flujo demostraron ser No-Inferiores a la Ventilación No-Invasiva en múltiples causas de Falla R…
Interesting considering how we work so hard to bring down FiO2 in our ventilated patients. https://t.co/ikjP0LXIml https://t.co/hleAcNEo0W
Early Restrictive vs Liberal Oxygen for Trauma Patients https://t.co/4uYsgKWPvR
RT @vm_aventho: Las Cánulas Nasales de Alto Flujo demostraron ser No-Inferiores a la Ventilación No-Invasiva en múltiples causas de Falla R…
RT @shiraishia_md: 外傷初期診療では、実証的な根拠がないまま必要量を超える酸素投与が推奨されてきた。それをテストしたランダム化比較試験 TRAUMOX2。 https://t.co/P0czcOyNwo
Una estrategia restrictiva de oxigenación (SpO2 94% con FiO2 promedio de 28%) es suficiente para mantener a los pacientes con Traumatismo Severo
Las Cánulas Nasales de Alto Flujo demostraron ser No-Inferiores a la Ventilación No-Invasiva en múltiples causas de Falla Respiratoria Aguda:
RT @so_flat: 酸素ターゲットのSR中ですがこんなの出ましたね。 Early Restrictive vs Liberal Oxygen for Trauma Patients: The TRAUMOX2 Randomized Clinical Trial | Tr…
RT @vm_aventho: Las Cánulas Nasales de Alto Flujo demostraron ser No-Inferiores a la Ventilación No-Invasiva en múltiples causas de Falla R…
RT @vm_aventho: Las Cánulas Nasales de Alto Flujo demostraron ser No-Inferiores a la Ventilación No-Invasiva en múltiples causas de Falla R…
RT @so_flat: 酸素ターゲットのSR中ですがこんなの出ましたね。 Early Restrictive vs Liberal Oxygen for Trauma Patients: The TRAUMOX2 Randomized Clinical Trial | Tr…
RT @so_flat: 酸素ターゲットのSR中ですがこんなの出ましたね。 Early Restrictive vs Liberal Oxygen for Trauma Patients: The TRAUMOX2 Randomized Clinical Trial | Tr…
酸素ターゲットのSR中ですがこんなの出ましたね。 Early Restrictive vs Liberal Oxygen for Trauma Patients: The TRAUMOX2 Randomized Clinical Trial | Trauma and Injury | JAMA | JAMA Network https://t.co/cY9dkhVO8I
RT @vm_aventho: Las Cánulas Nasales de Alto Flujo demostraron ser No-Inferiores a la Ventilación No-Invasiva en múltiples causas de Falla R…
RT @shiraishia_md: 外傷初期診療では、実証的な根拠がないまま必要量を超える酸素投与が推奨されてきた。それをテストしたランダム化比較試験 TRAUMOX2。 https://t.co/P0czcOyNwo
RT @shiraishia_md: 外傷初期診療では、実証的な根拠がないまま必要量を超える酸素投与が推奨されてきた。それをテストしたランダム化比較試験 TRAUMOX2。 https://t.co/P0czcOyNwo
Early Restrictive vs Liberal Oxygen for Trauma Patients: The TRAUMOX2 Randomized Clinical Trial | Trauma and Injury | JAMA | JAMA Network https://t.co/QhaOd4XkkZ
RT @vm_aventho: Las Cánulas Nasales de Alto Flujo demostraron ser No-Inferiores a la Ventilación No-Invasiva en múltiples causas de Falla R…
外傷初期診療では、実証的な根拠がないまま必要量を超える酸素投与が推奨されてきた。それをテストしたランダム化比較試験 TRAUMOX2。 https://t.co/P0czcOyNwo
RT @vm_aventho: Las Cánulas Nasales de Alto Flujo demostraron ser No-Inferiores a la Ventilación No-Invasiva en múltiples causas de Falla R…
RT @ParamedicHombr: Hochdosierte Sauerstoffgabe beim schweren Trauma? Bringt keine Benefits und möglicherweise Schäden: https://t.co/mqnz…
Early Restrictive vs Liberal Oxygen for Trauma Patients The TRAUMOX2 Randomized Clinical Trial jamanetwork.com/journals/jam...
RT @vm_aventho: Las Cánulas Nasales de Alto Flujo demostraron ser No-Inferiores a la Ventilación No-Invasiva en múltiples causas de Falla R…
RT @vm_aventho: Las Cánulas Nasales de Alto Flujo demostraron ser No-Inferiores a la Ventilación No-Invasiva en múltiples causas de Falla R…
RT @vm_aventho: Las Cánulas Nasales de Alto Flujo demostraron ser No-Inferiores a la Ventilación No-Invasiva en múltiples causas de Falla R…
RT @vm_aventho: Las Cánulas Nasales de Alto Flujo demostraron ser No-Inferiores a la Ventilación No-Invasiva en múltiples causas de Falla R…
RT @vm_aventho: Las Cánulas Nasales de Alto Flujo demostraron ser No-Inferiores a la Ventilación No-Invasiva en múltiples causas de Falla R…
外傷患者における酸素目標 ・病院前からERという外傷診療の最初期8時間にフォーカス ・死亡と重大な呼吸合併症の複合アウトカム ・ランダム化後の除外患者 ・2群間のSpO2の差 が注目ポイントだと思います。 https://t.co/dXd1xy53JV
RT @OrlandoRPN: Una estrategia restrictiva de oxigenación (SpO2 94% con FiO2 promedio de 28%) es suficiente para mantener a los pacientes c…
RT @OrlandoRPN: Una estrategia restrictiva de oxigenación (SpO2 94% con FiO2 promedio de 28%) es suficiente para mantener a los pacientes c…
RT @OrlandoRPN: Una estrategia restrictiva de oxigenación (SpO2 94% con FiO2 promedio de 28%) es suficiente para mantener a los pacientes c…
RT @OrlandoRPN: Una estrategia restrictiva de oxigenación (SpO2 94% con FiO2 promedio de 28%) es suficiente para mantener a los pacientes c…
RT @vm_aventho: Las Cánulas Nasales de Alto Flujo demostraron ser No-Inferiores a la Ventilación No-Invasiva en múltiples causas de Falla R…
RT @OrlandoRPN: Una estrategia restrictiva de oxigenación (SpO2 94% con FiO2 promedio de 28%) es suficiente para mantener a los pacientes c…
Una estrategia restrictiva de oxigenación (SpO2 94% con FiO2 promedio de 28%) es suficiente para mantener a los pacientes con Traumatismo Severo
Las Cánulas Nasales de Alto Flujo demostraron ser No-Inferiores a la Ventilación No-Invasiva en múltiples causas de Falla Respiratoria Aguda:
RT @JAMA_current: What is the impact of different oxygenation strategies for trauma patients, especially in the early phase after trauma?…
RT @OrlandoRPN: Una estrategia restrictiva de oxigenación (SpO2 94% con FiO2 promedio de 28%) es suficiente para mantener a los pacientes c…
RT @drkarenfortuna:
iniciada en el entorno prehospitalario
RT @MMarmiere: 2/ #TRAUMOX2trial
RT @OrlandoRPN: Una estrategia restrictiva de oxigenación (SpO2 94% con FiO2 promedio de 28%) es suficiente para mantener a los pacientes c…
RT @MMarmiere: 2/ #TRAUMOX2trial
"In severely injured trauma patients, an early restrictive oxygen strategy compared with a liberal oxygen strategy initiated ... did not significantly reduce mortality and/or major respiratory complications." https://t.co/qo4aUXcTfx
RT @Dra_TeraizaMesa: What is the impact of different oxygenation strategies for trauma patients, especially in the early phase after trauma…
In contrast to overall hospitalized patients where high quality evidence indicates liberally giving oxygen increases risk of mortality (IOTA study, Lancet 2018), according to a recent RCT, early restrictive O2 didnt reduce mortality in trauma patients https://t.co/nOgvSyP8bE
RT @Dra_TeraizaMesa: What is the impact of different oxygenation strategies for trauma patients, especially in the early phase after trauma…
RT @JAMA_current: What is the impact of different oxygenation strategies for trauma patients, especially in the early phase after trauma?…
RT @JAMA_current: What is the impact of different oxygenation strategies for trauma patients, especially in the early phase after trauma?…
What is the impact of different oxygenation strategies for trauma patients, especially in the early phase after trauma? Read more in this JAMA study published at #CCRdownunder. https://t.co/lmtoqeNEaK https://t.co/1ry56q7Ew8
RT @JAMA_current: What is the impact of different oxygenation strategies for trauma patients, especially in the early phase after trauma?…
What is the impact of different oxygenation strategies for trauma patients, especially in the early phase after trauma? Read more in this JAMA study published at #CCRdownunder. https://t.co/6bVBQ7hTaK https://t.co/T7yQM5mZK4
Hochdosierte Sauerstoffgabe beim schweren Trauma? Bringt keine Benefits und möglicherweise Schäden: https://t.co/mqnzZL2BcA
RT @MMarmiere: 2/ #TRAUMOX2trial
RT @MMarmiere: 2/ #TRAUMOX2trial
2/ #TRAUMOX2trial
Una estrategia restrictiva de oxigenación (SpO2 94% con FiO2 promedio de 28%) es suficiente para mantener a los pacientes con Traumatismo Severo
RT @JAMA_current: @CritCareReviews In severely injured trauma patients, an early restrictive oxygen strategy vs a liberal oxygen strategy d…
@CritCareReviews In severely injured trauma patients, an early restrictive oxygen strategy vs a liberal oxygen strategy did not reduce mortality and/or major respiratory complications. #CCRdownunder @CritCareReviews https://t.co/47Pu8H4YRp https://t.co/nv9fBITlPz
Early Restrictive vs Liberal Oxygen for Trauma Patients: The TRAUMOX2 Randomized Clinical Trial | Trauma and Injury | JAMA | JAMA Network https://t.co/7HVQpKmuDo
Early Restrictive vs Liberal Oxygen for Trauma Patients https://t.co/VFah5gS0oG
RT @JAMA_current: In severely injured trauma patients, an early restrictive oxygen strategy vs a liberal oxygen strategy did not reduce mor…
RT @precordialthump: Early Restrictive vs Liberal Oxygen for Trauma Patients: The #TRAUMOX2 Randomized Clinical Trial | @JAMA_current Jus…
RT @JAMA_current: In severely injured trauma patients, an early restrictive oxygen strategy vs a liberal oxygen strategy did not reduce mor…
RT @JAMA_current: In severely injured trauma patients, an early restrictive oxygen strategy vs a liberal oxygen strategy did not reduce mor…
RT @JAMA_current: In severely injured trauma patients, an early restrictive oxygen strategy vs a liberal oxygen strategy did not reduce mor…
RT @JAMA_current: In severely injured trauma patients, an early restrictive oxygen strategy vs a liberal oxygen strategy did not reduce mor…
RT @JAMA_current: In severely injured trauma patients, an early restrictive oxygen strategy vs a liberal oxygen strategy did not reduce mor…
RT @precordialthump: Early Restrictive vs Liberal Oxygen for Trauma Patients: The #TRAUMOX2 Randomized Clinical Trial | @JAMA_current Jus…
RT @precordialthump: Early Restrictive vs Liberal Oxygen for Trauma Patients: The #TRAUMOX2 Randomized Clinical Trial | @JAMA_current Jus…
Early Restrictive vs Liberal Oxygen for Trauma Patients: The #TRAUMOX2 Randomized Clinical Trial | JAMA - Just published! #ccrdownunder jamanetwork.com/journals/jam...
Early Restrictive vs Liberal Oxygen for Trauma Patients: The #TRAUMOX2 Randomized Clinical Trial | @JAMA_current Just published! #ccrdownunder https://t.co/zrZOELrSkD
RT @JAMA_current: In severely injured trauma patients, an early restrictive oxygen strategy vs a liberal oxygen strategy did not reduce mor…
RT @JAMA_current: In severely injured trauma patients, an early restrictive oxygen strategy vs a liberal oxygen strategy did not reduce mor…
In severely injured trauma patients, an early restrictive oxygen strategy vs a liberal oxygen strategy did not reduce mortality and/or major respiratory complications. #CCRdownunder @CritCareReviews https://t.co/faAf7S63Ok https://t.co/EpxYCbzIU6
And finally an interview with workgroup lead @JackResneckMD about the new revisions: https://t.co/p8rmXX3lf5 Thanks for reading! 11/11
RT @EdCriticalCare: The Declaration of Helsinki's ethical principles are central to clinical research. In response to a changing world, pre…
RT @EdCriticalCare: The Declaration of Helsinki's ethical principles are central to clinical research. In response to a changing world, pre…
The Declaration of Helsinki's ethical principles are central to clinical research. In response to a changing world, presenting new ethical risks to participants, the DoH has been revised. Here's a great wee video discussing it.. https://t.co/SVZenTCBK0 @medwma #ethics #safety