Telomerase reverse transcriptase gene knock-in unleashes enhanced longevity and accelerated damage repair in mice https://t.co/ISNamLMMEc
Telomerase reverse transcriptase gene knock-in unleashes enhanced longevity and accelerated damage repair in mice.
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Dec 2024 – Apr 2025Where it's discussed
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X / Twitter43 posts
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YouTube3 videos
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News3 articles
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Facebook2 posts
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Blogs2 articles
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Bluesky1 posts
AI synopsis
What people are saying
Discussions revolve around the promising results of TERT gene insertions, emphasizing potential breakthroughs in longevity and tissue repair, as seen in comments about 'unparalleled longevity' and 'potently rejuvenated skin.' The tone varies from enthusiastic to cautious, with some users pondering safe methods for application, which reflects both curiosity and recognition of the research's transformative potential.
Most discussions support the positive findings, highlighting the potential for increased lifespan and tissue regeneration without significant concern over risks.
Posts demonstrate high curiosity, mentioning specific details like median lifespan extension (16.57%) and applications such as skin and intestinal rejuvenation.
Several mentions of possible therapeutic uses, such as gene therapy and cosmetic applications, show deeper consideration and connection to real-world impacts.
The posts suggest the research could significantly influence aging science and treatments, with phrases indicating potential 'rejuvenation' and 'protection from colitis' serving as indicators of high perceived impact.
Abstract in brief
- This research explores how inserting the TERT gene into mice's genomes (via precise gene editing) extends their lifespan, boosts telomerase activity, and improves their ability to repair tissue damage without causing cancer.
- The Tert knockin mice showed faster wound healing, resistance to colitis, and better expression of growth factors like Fgf7 and Vegf, indicating enhanced tissue regeneration and reduced aging-related deterioration.
- Overall, the study suggests that germline TERT gene editing could be a powerful strategy for promoting longevity and tissue rejuvenation, particularly in aging skin and intestines, with minimal risk of adverse effects.]
Top posts
Most liked on X and BlueskyTelomerase reverse transcriptase gene knock-in unleashes enhanced longevity and accelerated damage repair in mice https://t.co/1Ix5uZfV2v
Telomerase reverse transcriptase gene knock-in unleashes enhanced longevity and accelerated damage repair in mice https://t.co/8vulHVp3fm https://t.co/HJC5v0PT7f
hTERT knock-in mice have potently rejuvenated skin and are protected from colitis. Could we safely introduce hTERT into skin as a cosmetic? We would stay away from permanent transfection... https://t.co/OCe6CKMCVg
The last Longevity Review of 2024 is here for your viewing pleasure! Contents: 1. Gene Therapy To Increase Telomere Length 2. Freeing The Immune System To Remove Senescent Cells 3. Using Probiotics To Help With Sarcopenia 1/2 https://t.co/4oDnYdWILZ
Unparalleled #longevity? This study shows the median #lifespan of TertKI (Telomerase reverse transcriptase gene knock-in) mice was extended by 16.57%, and regenerative potential in skin and intestinal #aging. https://t.co/MgA5so3RVw
All mentions
Genetic Advances Boost Longevity and Tissue Repair in Mice
Recent scientific breakthroughs include relocating a gene from mitochondria to the nucleus and enhancing telomerase expression in mice, leading to increased lifespan, improved tissue repair, and no rise in cancer risk.
Telomerase Gene Editing Extends Lifespan and Enhances Tissue Repair in Mice
This study demonstrates that transgenic mice expressing telomerase throughout their bodies not only did not develop more cancer but also experienced increased lifespan, improved tissue repair, and reduced aging-related…
Advances in Longevity Research December 2024 Review
A review of the most interesting and impactful longevity related studies from December including how gene therapy can increase telomere length and how the immune system can be used to clear senescent cells. The research…
RT @agingdoc1: Telomerase reverse transcriptase gene knock-in unleashes enhanced longevity and accelerated damage repair in mice https://t…
RT @agingdoc1: Telomerase reverse transcriptase gene knock-in unleashes enhanced longevity and accelerated damage repair in mice https://t…
RT @agingdoc1: Telomerase reverse transcriptase gene knock-in unleashes enhanced longevity and accelerated damage repair in mice https://t…
RT @agingdoc1: Telomerase reverse transcriptase gene knock-in unleashes enhanced longevity and accelerated damage repair in mice https://t…
RT @agingdoc1: Telomerase reverse transcriptase gene knock-in unleashes enhanced longevity and accelerated damage repair in mice https://t…
RT @agingdoc1: Telomerase reverse transcriptase gene knock-in unleashes enhanced longevity and accelerated damage repair in mice https://t…
RT @agingdoc1: Telomerase reverse transcriptase gene knock-in unleashes enhanced longevity and accelerated damage repair in mice https://t…
Telomerase reverse transcriptase gene knock-in unleashes enhanced longevity and accelerated damage repair in mice https://t.co/1Ix5uZfV2v
RT @canlongevity: The last Longevity Review of 2024 is here for your viewing pleasure! Contents: 1. Gene Therapy To Increase Telomere Le…
The last Longevity Review of 2024 is here for your viewing pleasure! Contents: 1. Gene Therapy To Increase Telomere Length 2. Freeing The Immune System To Remove Senescent Cells 3. Using Probiotics To Help With Sarcopenia 1/2 https://t.co/4oDnYdWILZ
RT @AgingBiology: Telomerase reverse transcriptase gene knock-in unleashes enhanced longevity and accelerated damage repair in mice https:/…
RT @agingdoc1: Telomerase reverse transcriptase gene knock-in unleashes enhanced longevity and accelerated damage repair in mice https://t…
Telomerase reverse transcriptase gene knock-in unleashes enhanced longevity and accelerated damage repair in mice #agingresearch onlinelibrary.wiley.com/doi/10.1111/...
@isaacofthebio @yannToskov "Telomerase reverse transcriptase gene knock-in unleashes enhanced longevity and accelerated damage repair in mice" https://t.co/zUEwozwER5
Telomerase reverse transcriptase gene knock-in unleashes enhanced longevity and accelerated damage repair in mice https://t.co/8vulHVp3fm https://t.co/HJC5v0PT7f
RT @AgingBiology: Telomerase reverse transcriptase gene knock-in unleashes enhanced longevity and accelerated damage repair in mice https:/…
Unparalleled #longevity? This study shows the median #lifespan of TertKI (Telomerase reverse transcriptase gene knock-in) mice was extended by 16.57%, and regenerative potential in skin and intestinal #aging. https://t.co/MgA5so3RVw
RT @AgingBiology: Telomerase reverse transcriptase gene knock-in unleashes enhanced longevity and accelerated damage repair in mice https:/…
RT @AgingBiology: Telomerase reverse transcriptase gene knock-in unleashes enhanced longevity and accelerated damage repair in mice https:/…
RT @AgingBiology: Telomerase reverse transcriptase gene knock-in unleashes enhanced longevity and accelerated damage repair in mice https:/…
RT @AgingBiology: Telomerase reverse transcriptase gene knock-in unleashes enhanced longevity and accelerated damage repair in mice https:/…
RT @AgingBiology: Telomerase reverse transcriptase gene knock-in unleashes enhanced longevity and accelerated damage repair in mice https:/…
RT @AgingBiology: Telomerase reverse transcriptase gene knock-in unleashes enhanced longevity and accelerated damage repair in mice https:/…
RT @AgingBiology: Telomerase reverse transcriptase gene knock-in unleashes enhanced longevity and accelerated damage repair in mice https:/…
RT @AgingBiology: Telomerase reverse transcriptase gene knock-in unleashes enhanced longevity and accelerated damage repair in mice https:/…
RT @AgingBiology: Telomerase reverse transcriptase gene knock-in unleashes enhanced longevity and accelerated damage repair in mice https:/…
RT @AgingBiology: Telomerase reverse transcriptase gene knock-in unleashes enhanced longevity and accelerated damage repair in mice https:/…
RT @AgingBiology: Telomerase reverse transcriptase gene knock-in unleashes enhanced longevity and accelerated damage repair in mice https:/…
RT @AgingBiology: Telomerase reverse transcriptase gene knock-in unleashes enhanced longevity and accelerated damage repair in mice https:/…
RT @AgingBiology: Telomerase reverse transcriptase gene knock-in unleashes enhanced longevity and accelerated damage repair in mice https:/…
RT @AgingBiology: Telomerase reverse transcriptase gene knock-in unleashes enhanced longevity and accelerated damage repair in mice https:/…
hTERT knock-in mice have potently rejuvenated skin and are protected from colitis. Could we safely introduce hTERT into skin as a cosmetic? We would stay away from permanent transfection... https://t.co/OCe6CKMCVg
RT @AgingBiology: Telomerase reverse transcriptase gene knock-in unleashes enhanced longevity and accelerated damage repair in mice https:/…
RT @AgingBiology: Telomerase reverse transcriptase gene knock-in unleashes enhanced longevity and accelerated damage repair in mice https:/…
RT @AgingBiology: Telomerase reverse transcriptase gene knock-in unleashes enhanced longevity and accelerated damage repair in mice https:/…
RT @AgingBiology: Telomerase reverse transcriptase gene knock-in unleashes enhanced longevity and accelerated damage repair in mice https:/…
RT @AgingBiology: Telomerase reverse transcriptase gene knock-in unleashes enhanced longevity and accelerated damage repair in mice https:/…
RT @AgingBiology: Telomerase reverse transcriptase gene knock-in unleashes enhanced longevity and accelerated damage repair in mice https:/…
RT @AgingBiology: Telomerase reverse transcriptase gene knock-in unleashes enhanced longevity and accelerated damage repair in mice https:/…
RT @AgingBiology: Telomerase reverse transcriptase gene knock-in unleashes enhanced longevity and accelerated damage repair in mice https:/…
RT @AgingBiology: Telomerase reverse transcriptase gene knock-in unleashes enhanced longevity and accelerated damage repair in mice https:/…
RT @AgingBiology: Telomerase reverse transcriptase gene knock-in unleashes enhanced longevity and accelerated damage repair in mice https:/…
RT @AgingBiology: Telomerase reverse transcriptase gene knock-in unleashes enhanced longevity and accelerated damage repair in mice https:/…
Telomerase reverse transcriptase gene knock-in unleashes enhanced longevity and accelerated damage repair in mice https://t.co/ISNamLMMEc