Comparative Clinical Study on Magnesium Absorption and Side Effects After Oral Intake of Microencapsulated Magnesium (MAGSHAPE Microcapsules) Versus Other Magnesium Sources.

Abstract in brief

• The study compared the absorption and side effects of a new microencapsulated magnesium supplement (MAGSHAPE or MgMS) to other common magnesium sources like Mg oxide, Mg citrate, and Mg bisglycinate, finding that MgMS led to a sustained and significant increase in blood magnesium levels over 6 hours.
• MgMS showed higher bioavailability and better absorption than Mg oxide, which only increased magnesium levels at 1 and 4 hours, and Mg bisglycinate, which did not significantly raise magnesium levels at all, while Mg citrate increased levels temporarily at 4 hours.
• Additionally, MgMS was associated with fewer side effects such as gastrointestinal heaviness and increased intestinal motility, making it potentially a more tolerable option for magnesium supplementation.