The group expresses skepticism about the technical reliability of pyrolysis methods, emphasizing potential overestimation issues and methodological flaws, especially when applied to fatty tissues. Words like 'unreliable' and phrases questioning common assumptions, such as 'your brain contains a plastic spoonful of microplastic,' highlight critical engagement and concern over current scientific claims.
AgreementLow agreement
Most posts question the reliability of pyrolysis-GC-MS for detecting microplastics in blood, suggesting disagreement with the publication’s optimistic view.
InterestModerate interest
Discussions show moderate interest, especially among those familiar with methodological challenges in microplastic detection.
EngagementModerate engagement
Posts involve critical analysis and references to expert opinions, indicating active engagement.
ImpactNeutral impact
The discourse raises awareness of technical limitations but does not seem to suggest a major shift in policy or public health impact yet.
Abstract in brief
The study evaluated the use of pyrolysis-gas chromatography-mass spectrometry (Py-GC-MS) to detect nanoplastic and microplastic polymers, like PE and PVC, in human blood, but found that current techniques face challenges due to interference from biological components.
Although the researchers improved extraction methods and developed realistic detection limits, the presence of false positives and matrix interference issues made it difficult to reliably quantify certain plastics, especially PE and PVC, in blood samples.
The conclusion was that Py-GC-MS, in its current state, is not suitable for analyzing plastics in biological samples, though detecting some polymer exposure in blood is possible at levels close to the method’s detection limits.]
Super important methodological implications for studies on #microplastics in humans, which currently tend to overestimate microplastic levels if Pyrolysis–Gas Chromatography–Mass Spectrometry is used, especcially for fatty tissues. https://t.co/MTAwLu6X8c
Feb 5, 2025 · 14 likes · 7 shares · 6,383 followersView post →
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Dr Michelle Wong
@LabMuffin · X
@LazarusLong13 @Dr_Oli_Jones @TheEcoWell Do you really think the brain has more microplastic than wastewater? Or more microplastic than the kidneys, a filtering organ? Or is it more likely they messed up in a well documented way? https://t.co/vo6gCA6wBg
Mar 14, 2025 · 3 likes · 35,367 followersView post →
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Dr Nate
@latentcharon.bsky.social · Bluesky
Excellent research from UQ's Queensland Alliance for Environmental Health Sciences (QAEHS).
"Assessing the Efficacy of Pyrolysis–Gas Chromatography–Mass Spectrometry for Nanoplastic and Microplastic Analysis in Human Blood"
#OzChem #ChemSky #QAEHS
pubs.acs.org/doi/10.1021/...
May 21, 2025 · 2 likes · 1 share · 2,905 followersView post →
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Dr. Melanie Bergmann
@MelanieBergma18 · X
@CodosTweet Die Zweifel sind begründet, wie ich von verschiedenen Expert:innen, die gesichert frei von Interessenskonflikten sind, weiß. Leider haben sich viele Kolleg:innen aus dem Medizin Bereich nicht die Methodik-Erfahrungen aus dem Umweltbereich zueigen gemacht. https://t.co/vlOn9ttppc
Mar 11, 2025 · 1 like · 1 share · 6,383 followersView post →
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Kermit Murray
@kkmurray.bsky.social · Bluesky
(ES&T) [ASAP] Assessing the Efficacy of Pyrolysis–Gas Chromatography–Mass Spectrometry for Nanoplastic and Microplastic Analysis in Human Blood: Environmental Science & TechnologyDOI: 10.1021/acs.est.4c12599 http://dlvr.it/THZ08l (RSS) #MassSpecRSS
Researchers reveal that the commonly used Pyrolysis-GC/MS method for detecting microplastics in humans may generate false positives due to interference, prompting a reevaluation of previous findings about microplastic…
This video reviews the recent evaluation of pyrolysis-gas chromatography-mass spectrometry for detecting nanoplastics and microplastics in human blood, highlighting current challenges like biological interference and…
In relation to a podcast that i won’t smear here, pyrolysis methods to quantify microplastic content is eminently unreliable and repeating things like “your brain contains a plastic spoonful of microplastic” will not age well.
https://t.co/3uxBcylqc6
May 21, 2025 · 2 likes · 1 share · 2,905 followersView post →
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Dr Nate
@latentcharon.bsky.social · Bluesky
A great write-up in LCGC International, discussing with Dr. Rauert her and her colleagues' recent paper:
"Assessing the Efficacy of Pyrolysis-Gas Chromatography-Mass Spectrometry for Nanoplastic and Microplastic Analysis in Human Blood"
#OzChem #ChemSky #Chromatography #GCMS #Microplastics
@LazarusLong13 @Dr_Oli_Jones @TheEcoWell Do you really think the brain has more microplastic than wastewater? Or more microplastic than the kidneys, a filtering organ? Or is it more likely they messed up in a well documented way? https://t.co/vo6gCA6wBg
Mar 14, 2025 · 3 likes · 35,367 followersView post →
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Codo
@CodosTweet · X
RT @MelanieBergma18: @CodosTweet Die Zweifel sind begründet, wie ich von verschiedenen Expert:innen, die gesichert frei von Interessenskonf…
Mar 11, 2025 · 1 share · 1,894 followersView post →
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Dr. Melanie Bergmann
@MelanieBergma18 · X
@CodosTweet Die Zweifel sind begründet, wie ich von verschiedenen Expert:innen, die gesichert frei von Interessenskonflikten sind, weiß. Leider haben sich viele Kolleg:innen aus dem Medizin Bereich nicht die Methodik-Erfahrungen aus dem Umweltbereich zueigen gemacht. https://t.co/vlOn9ttppc
Mar 11, 2025 · 1 like · 1 share · 6,383 followersView post →
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stylish yet illegal boy
@boltongoggins · X
RT @MelanieBergma18: Super important methodological implications for studies on #microplastics in humans, which currently tend to overestim…
Super important methodological implications for studies on #microplastics in humans, which currently tend to overestimate microplastic levels if Pyrolysis–Gas Chromatography–Mass Spectrometry is used, especcially for fatty tissues. https://t.co/MTAwLu6X8c
Feb 5, 2025 · 14 likes · 7 shares · 6,383 followersView post →
DN
Dr Nate
@latentcharon.bsky.social · Bluesky
Excellent research from UQ's Queensland Alliance for Environmental Health Sciences (QAEHS).
"Assessing the Efficacy of Pyrolysis–Gas Chromatography–Mass Spectrometry for Nanoplastic and Microplastic Analysis in Human Blood"
#OzChem #ChemSky #QAEHS
pubs.acs.org/doi/10.1021/...
(ES&T) [ASAP] Assessing the Efficacy of Pyrolysis–Gas Chromatography–Mass Spectrometry for Nanoplastic and Microplastic Analysis in Human Blood: Environmental Science & TechnologyDOI: 10.1021/acs.est.4c12599 http://dlvr.it/THZ08l (RSS) #MassSpecRSS
Assessing the Efficacy of Pyrolysis–Gas Chromatography–Mass Spectrometry for Nanoplastic and Microplastic Analysis in Human Blood #EST pubs.acs.org/doi/10.1021/...
Careful analytical study: doi.org/10.1021/acs.est.4c12599,. Discussion of analytical problems with reports of microplastics in blood and distal organs: https ...
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