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Nat Biotechnol February 2025 PMID 39905264

Implantation of engineered adipocytes suppresses tumor progression in cancer models.

Hai P Nguyen, Kelly An, Yusuke Ito, Bhushan N Kharbikar, Rory Sheng, Breanna Paredes, Elizabeth Murray, Kimberly Pham, Michael Bruck, Xujia Zhou, Cassandra Biellak, Aki Ushiki, Mai Nobuhara, Sarah L Fong, Daniel A Bernards

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Mentions

172
Peak: 80 in Feb 2025
across 7 sources since Feb 2025

Extended reach

597,227
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Total likes

355

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Feb 2025 – Jun 2025

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AI synopsis

What people are saying

The digital discussions consistently praise the article, with phrases like 'significant suppression of tumor growth' and 'innovative method,' highlighting how the wording conveys excitement and perceived importance. The frequent sharing of links and mention of future potential reflect high engagement and perceived impact.

AgreementStrong agreement

Most discussions express strong support and enthusiasm for the research findings, emphasizing the significance of engineering adipocytes to halt tumor growth.

InterestHigh interest

The posts demonstrate high curiosity and engagement, with many referencing the paper directly, sharing links, and highlighting the innovative aspects of the study.

EngagementHigh engagement

Users actively discuss implications, praise the methodology, and consider future applications, indicating deep involvement with the content.

ImpactHigh impact

The widespread sharing, positive tone, and emphasis on the potential transformative impact of this research suggest that the discussions see it as highly impactful in cancer therapy.

Abstract in brief

  • Tumors are adept at acquiring and using nutrients, prompting researchers to explore a method called adipose manipulation transplantation (AMT) to slow cancer progression.
  • Engineered adipocytes, modified to increase glucose and fatty acid uptake, were shown to significantly suppress cancer cell growth when placed alongside tumors in various experiments.
  • By transplanting these modified adipose organoids into mouse models of pancreatic and breast cancer, researchers demonstrated reduced tumor growth and vascularization, highlighting the customizable potential of AMT in targeting different cancer types.
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Nature Biotechnology
@NatureBiotech · X

Implantation of engineered adipocytes suppresses tumor progression in cancer models https://t.co/leLxy8RO10 https://t.co/2NhxyEaQrw

Feb 4, 2025 · 264 likes · 68 shares · 318,369 followers View post →
Nature Biotechnology
@natbiotech.nature.com · Bluesky

Implantation of engineered adipocytes suppresses tumor progression in cancer models - @nadavahituv.bsky.social go.nature.com/4gqhxvw

Feb 4, 2025 · 46 likes · 15 shares View post →
Dana-Farber’s Breast Oncology Center
@DFCI_BreastOnc · X

New paper in @NatureBiotech shows that the implantation of engineered adipocytes suppresses tumor progression in cancer models, read it here:

Mar 24, 2025 · 7 likes · 4 shares · 6,912 followers View post →
Paul Geeleher
@PGeeleher · X

Implantation of engineered adipocytes suppresses tumor progression in cancer models https://t.co/ZbYc9YBaeQ

Feb 5, 2025 · 5 likes · 1 share · 652 followers View post →
Wafik S. El-Deiry, MD, PhD, FACP
@weldeiry · X

Implantation of engineered adipocytes suppresses tumor progression in cancer models https://t.co/IgOekcNnPQ

Feb 5, 2025 · 4 likes · 18,079 followers View post →
サイエンスあれこれ
@sarekore · X

がん治療の魅力的なプラットフォームとなる可能性があります。Nature Biotechnology誌https://t.co/XsVvkE2CUk

Feb 5, 2025 · 4 likes · 922 followers View post →

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Man_of_caliber
@Manofcaliber4 · X

RT @NatureBiotech: Implantation of engineered adipocytes suppresses tumor progression in cancer models https://t.co/leLxy8RO10 https://t.co…

Jun 14, 2025 · 68 shares · 5 followers View post →
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RT @NatureBiotech: Implantation of engineered adipocytes suppresses tumor progression in cancer models https://t.co/leLxy8RO10 https://t.co…

May 30, 2025 · 68 shares · 401 followers View post →
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RT @NatureBiotech: Implantation of engineered adipocytes suppresses tumor progression in cancer models https://t.co/leLxy8RO10 https://t.co…

May 17, 2025 · 68 shares · 276 followers View post →
darcy darnoc
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Implantation of engineered adipocytes suppresses tumor progression in cancer models | Nature Biotechnology - Wish we could build a cage to surround a liver that has multi mets and see the results ⁦@MDAndersonNews⁩ https://t.co/br7UcjgjIE

May 16, 2025 · 3,115 followers View post →
darcy darnoc
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Implantation of engineered adipocytes suppresses tumor progression in cancer models | Nature Biotechnology https://t.co/br7UcjgjIE

May 16, 2025 · 3,115 followers View post →
Lorenzo Ferri MD PhD
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RT @NatureBiotech: Implantation of engineered adipocytes suppresses tumor progression in cancer models https://t.co/leLxy8RO10 https://t.co…

May 15, 2025 · 68 shares · 1,723 followers View post →
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progMāris
@progmars · X

@RudensLapaVeeja Lai daudz izturības! Nesen pamanīju publikācijas par jaunu, šķietami vienkāršu un efektīvu vēža ārstēšanas metodi ("Implantation of engineered adipocytes suppresses tumor progression in cancer models"), taču laikam jau paies gadi, kamēr tā izies pārbaudes un nonāks pie mums.

May 14, 2025 · 1 like · 28 followers View post →
News HQ
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May 7, 2025 · 68 shares · 499 followers View post →
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Filipa Lynce, MD, FASCO
@FilipaLynce · X

RT @DFCI_BreastOnc: New paper in @NatureBiotech shows that the implantation of engineered adipocytes suppresses tumor progression in cancer…

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Jonas Beck
@inno_jbeck · X

RT @DFCI_BreastOnc: New paper in @NatureBiotech shows that the implantation of engineered adipocytes suppresses tumor progression in cancer…

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Liam Harris
@lh_innovations · X

RT @DFCI_BreastOnc: New paper in @NatureBiotech shows that the implantation of engineered adipocytes suppresses tumor progression in cancer…

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Tejal A. Desai
@TejalADesai · X

RT @DFCI_BreastOnc: New paper in @NatureBiotech shows that the implantation of engineered adipocytes suppresses tumor progression in cancer…

Mar 24, 2025 · 4 shares · 4,356 followers View post →
Dana-Farber’s Breast Oncology Center
@DFCI_BreastOnc · X

New paper in @NatureBiotech shows that the implantation of engineered adipocytes suppresses tumor progression in cancer models, read it here:

Mar 24, 2025 · 7 likes · 4 shares · 6,912 followers View post →
Javier Méndez
@DrPatronus · X

RT @NatureBiotech: Implantation of engineered adipocytes suppresses tumor progression in cancer models https://t.co/leLxy8RO10 https://t.co…

Mar 24, 2025 · 68 shares · 137 followers View post →
Dana-Farber’s Breast Oncology Center
@DFCI_BreastOnc · X

RT @NatureBiotech: Implantation of engineered adipocytes suppresses tumor progression in cancer models https://t.co/leLxy8RO10 https://t.co…

Mar 24, 2025 · 68 shares · 6,912 followers View post →
Dana-Farber’s Breast Oncology Center
@DFCI_BreastOnc · X

RT @ScienceCrisp: "Implantation of engineered adipocytes suppresses tumor progression in cancer models" Nguyen HP (deceased) [..] Ahituv N.…

Mar 24, 2025 · 1 share · 6,912 followers View post →
PPBI
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Feb 27, 2025 · 68 shares · 714 followers View post →
Agingdoc
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Feb 26, 2025 · 2 likes · 41,229 followers View post →
旅人 tabito
@tabibito250 · X

Implantation of engineered adipocytes suppresses tumor progression in cancer models | Nature Biotechnology https://t.co/hUBXRZxS52

Feb 23, 2025 · 1,073 followers View post →
Rosanna Royo i Pla
@RosannaRoyoiPla · X

RT @JovitaMezquita: Gen Genetic Engineering 2025,   https://t.co/xuUsvhYKyv Referència: Nguyen, H.P., An, K., Ito, Y. et al. Implantation o…

Feb 23, 2025 · 1 share · 9,259 followers View post →
Jovita Mezquita Pla
@JovitaMezquita · X

Gen Genetic Engineering 2025,   https://t.co/xuUsvhYKyv Referència: Nguyen, H.P., An, K., Ito, Y. et al. Implantation of engineered adipocytes suppresses tumor progression in cancer models. Nat Biotechnol (2025). https://t.co/BRhJvvsQUs

Feb 23, 2025 · 2 likes · 1 share · 647 followers View post →
Jovita Mezquita Pla
@jovitamezquitapla.bsky.social · Bluesky

Referència: Nguyen, H.P., An, K., Ito, Y. et al. Implantation of engineered adipocytes suppresses tumor progression in cancer models. Nat Biotechnol (2025). doi.org/10.1038/s415...

Feb 23, 2025 · 1 share View post →
旅人 tabito
@tabibito250 · X

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Shyam Prabhakar Lab
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Feb 21, 2025 · 68 shares · 21 followers View post →
Little BiB
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Feb 21, 2025 · 68 shares · 555 followers View post →
AlMotasem Bellah
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Feb 19, 2025 · 68 shares · 29 followers View post →
OZ BIOSCIENCES
@OZBIOSCIENCES · X

New paper!

Feb 13, 2025 · 308 followers View post →
Melody yang
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Feb 12, 2025 · 68 shares · 20 followers View post →
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Feb 12, 2025 · 68 shares · 698 followers View post →
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Feb 12, 2025 · 68 shares · 1,386 followers View post →
HealthyBuilds
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HealthyBuilds
@HealthyBuilds · X

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CRISP_SCIENCE
@ScienceCrisp · X

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Feb 11, 2025 · 3 likes · 1 share · 1,915 followers View post →
HealthyBuilds
@HealthyBuilds · X

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HealthyBuilds
@JamesSw70043542 · X

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Idris Soyinka
@Idris_Soyinka · X

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Feb 6, 2025 · 68 shares · 1 followers View post →
Holtz
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Feb 6, 2025 · 2 likes · 1 share · 8,892 followers View post →
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@rahmanLAB2023 · X

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Wafik S. El-Deiry, MD, PhD, FACP
@weldeiry.bsky.social · Bluesky

Implantation of engineered adipocytes suppresses tumor progression in cancer models www.nature.com/articles/s41...

Feb 5, 2025 · 1 like View post →
Wafik S. El-Deiry, MD, PhD, FACP
@weldeiry · X

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@PGeeleher · X

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@kgusler · X

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サイエンスあれこれ
@sarekore · X

がん治療の魅力的なプラットフォームとなる可能性があります。Nature Biotechnology誌https://t.co/XsVvkE2CUk

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Feb 4, 2025 · 68 shares · 520 followers View post →
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Feb 4, 2025 · 68 shares · 111 followers View post →
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Mahmoud Sami
@AIMahmoudSami · X

RT @NatureBiotech: Implantation of engineered adipocytes suppresses tumor progression in cancer models https://t.co/leLxy8RO10 https://t.co…

Feb 4, 2025 · 68 shares · 3 followers View post →
Nature Biotechnology
@NatureBiotech · X

Implantation of engineered adipocytes suppresses tumor progression in cancer models https://t.co/leLxy8RO10 https://t.co/2NhxyEaQrw

Feb 4, 2025 · 264 likes · 68 shares · 318,369 followers View post →
Yuqin
@yuqincai · X

Implantation of engineered adipocytes suppresses tumor progression in cancer models | Nature Biotechnology https://t.co/1GjLMMz2Zy

Feb 4, 2025 · 263 followers View post →
Nature Biotechnology
@natbiotech.nature.com · Bluesky

Implantation of engineered adipocytes suppresses tumor progression in cancer models - @nadavahituv.bsky.social go.nature.com/4gqhxvw

Feb 4, 2025 · 46 likes · 15 shares View post →