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JAMA Cardiol April 2025 PMID 39908026

Salt Substitution and Recurrent Stroke and Death: A Randomized Clinical Trial.

Xiong Ding, Xinyi Zhang, Liping Huang, Shangzhi Xiong, Zhifang Li, Yi Zhao, Bo Zhou, Xuejun Yin, Bingqing Xu, Yanfeng Wu, Bruce Neal, Maoyi Tian, Lijing L Yan

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Mentions

110
Peak: 46 in Feb 2025
across 7 sources since Feb 2025

Extended reach

1,599,298
potential audience

Total likes

267

Video views

134

Mentions per month

Feb 2025 – Jun 2025

Where it's discussed

  • X / Twitter61 posts
  • News38 articles
  • Blogs4 articles
  • YouTube2 videos
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  • Reddit2 posts
  • Bluesky1 posts

AI synopsis

What people are saying

Many discussions emphasize the practical implications of the research, noting how a simple switch in salt type could lead to a 14% reduction in recurrent stroke risk and 12% reduction in mortality. Phrases like 'reduce the risk of stroke with a simple salt change' and 'salt substitution is safe' reflect a tone of excitement and urgency, showcasing a consensus on the study's importance for improving health outcomes.

AgreementStrong agreement

The discussions overwhelmingly support the findings of the study, highlighting the benefits of using salt substitutes.

InterestHigh interest

Participants exhibit high curiosity about the study's results and implications for stroke patients.

EngagementModerate engagement

While the engagement level is moderate, many posts reference specific findings without an in-depth critique or analysis.

ImpactHigh impact

The collective perception indicates a strong belief that the findings could significantly influence public health practices regarding diet and stroke prevention.

Abstract in brief

  • The study evaluated the effects of salt substitutes versus regular salt on recurrent stroke and mortality rates in stroke patients across 600 Chinese villages.
  • Results showed that the use of salt substitutes significantly reduced instances of recurrent stroke and death, especially in cases of hemorrhagic stroke and stroke-related deaths.
  • Overall, the trial suggests that using salt substitutes is safe and can lead to significant health benefits for stroke patients, without increased risks of hyperkalemia (high potassium levels).
Read the full abstract

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Ramiro Esparza
@docramiro · X

Sustitutos de sal y riesgo de evento cerebral vascular Referencia: doi:10.1001/jamacardio.2024.5417 https://t.co/qG3leGdj19

Feb 6, 2025 · 180 likes · 28 shares · 68,312 followers View post →
JAMA
@JAMA_current · X

From @JAMACardio: Using salt substitutes instead of regular salt reduced the rates of recurrent stroke and mortality among patients with a history of stroke in rural China, without increasing the risk of hyperkalemia. https://t.co/JInUzgkDRd @MaoyiT https://t.co/vnf65GBlNt

Feb 5, 2025 · 18 likes · 5 shares · 488,081 followers View post →
JAMA Cardiology
@JAMACardio · X

Using salt substitutes instead of regular salt reduced the rates of recurrent stroke and mortality among patients with a history of stroke in rural China, without increasing the risk of hyperkalemia. https://t.co/PaYWAQJ68T @MaoyiT https://t.co/CN3e3lGb2y

Feb 5, 2025 · 15 likes · 3 shares · 47,815 followers View post →
JAMA Neurology
@JAMANeuro · X

From @JAMACardio: Using salt substitutes instead of regular salt reduced the rates of recurrent stroke and mortality among patients with a history of stroke in rural China, without increasing the risk of hyperkalemia. https://t.co/RrBg2vnC3W @MaoyiT https://t.co/Bbzrz87HKg

Feb 5, 2025 · 9 likes · 1 share · 65,066 followers View post →
JAMA Cardiology
@JAMACardio · X

Using salt substitutes instead of regular salt reduced the rates of recurrent stroke and mortality among patients with a history of stroke in rural China, without increasing the risk of hyperkalemia. https://t.co/V96G0Lru5n @MaoyiT

Apr 15, 2025 · 6 likes · 4 shares · 47,815 followers View post →
Saber Atualizado
@AtualizadoSaber · X

(1) Publicação do estudo: Ding et al. (2025). Salt Substitution and Recurrent Stroke and Death: A Randomized Clinical Trial. JAMA Cardiology. https://t.co/D4OzQzMPzF

Mar 9, 2025 · 6 likes · 1 share · 30,177 followers View post →

All mentions

Marta Guillan
@Martaguillan · X

RT @AMAREVA_Madrid: Salt Substitution and Recurrent Stroke and Death – A Randomized Clinical Trial https://t.co/THf8KFWbwJ https://t.co/JlY…

Jun 6, 2025 · 3 shares · 976 followers View post →
esther rubio
@draerubio · X

RT @AMAREVA_Madrid: Salt Substitution and Recurrent Stroke and Death – A Randomized Clinical Trial https://t.co/THf8KFWbwJ https://t.co/JlY…

May 28, 2025 · 3 shares · 751 followers View post →
Teresa Gijon Conde
@TGijonConde · X

RT @AMAREVA_Madrid: Salt Substitution and Recurrent Stroke and Death – A Randomized Clinical Trial https://t.co/THf8KFWbwJ https://t.co/JlY…

May 18, 2025 · 3 shares · 1,056 followers View post →
AMAREVA Riesgo Vascular
@AMAREVA_Madrid · X

Salt Substitution and Recurrent Stroke and Death – A Randomized Clinical Trial https://t.co/THf8KFWbwJ https://t.co/JlY2kWLItP

May 18, 2025 · 4 likes · 3 shares · 380 followers View post →
Elea Rom
@Lbnromro · X

Más información: Ding X, Zhang X, Huang L, et al. Salt Substitution and Recurrent Stroke and Death: A Randomized Clinical Trial. JAMA Cardiol. Published online February 05, 2025. https://t.co/CdY0mWpKhq

Apr 28, 2025 · 5 followers View post →
Elea Rom
@Lbnromro · X

¡Reduce el riesgo de derrame cerebral con un simple cambio de sal!

Apr 28, 2025 · 5 followers View post →
Doctor_David
@Doctor_David · X

RT @JAMACardio: Using salt substitutes instead of regular salt reduced the rates of recurrent stroke and mortality among patients with a hi…

Apr 15, 2025 · 4 shares · 2,676 followers View post →
MICHAEL MILLER MD, MASPC
@mmillermd1 · X

RT @JAMACardio: Using salt substitutes instead of regular salt reduced the rates of recurrent stroke and mortality among patients with a hi…

Apr 15, 2025 · 4 shares · 5,009 followers View post →
John P Erwin III MD MBA MACC (#BigPoppy )
@HeartOTXHeartMD · X

RT @JAMACardio: Using salt substitutes instead of regular salt reduced the rates of recurrent stroke and mortality among patients with a hi…

Apr 15, 2025 · 4 shares · 39,669 followers View post →
JAMA Cardiology
@JAMACardio · X

Using salt substitutes instead of regular salt reduced the rates of recurrent stroke and mortality among patients with a history of stroke in rural China, without increasing the risk of hyperkalemia. https://t.co/V96G0Lru5n @MaoyiT

Apr 15, 2025 · 6 likes · 4 shares · 47,815 followers View post →
Maria Hazel Cohan, DNP, AGACNP-BC, AACC
@mcvhaze · X

Salt Substitution and Recurrent Stroke and Death https://t.co/G0LMdLGJq6

Apr 10, 2025 · 134 followers View post →
JAMA Network
@JAMANetwork · X

Attending #ACC25? Supplement your schedule with Salt Substitution and Recurrent Stroke and Death: A Randomized Clinical Trial, from @JAMACardio. Free to read online during the meeting https://t.co/8MHz5OFhIk https://t.co/d0o5dzd7qw

Mar 30, 2025 · 1 like · 19,627 followers View post →
JAMA Cardiology
@JAMACardio · X

Attending #ACC25? Supplement your schedule with Salt Substitution and Recurrent Stroke and Death: A Randomized Clinical Trial, from JAMA Cardiology. Free to read online during the meeting https://t.co/gqXkwldEqE https://t.co/5igXksNmfJ

Mar 30, 2025 · 47,815 followers View post →
おくさん/OKUSUN
@Astella6174 · X

【脳卒中患者に朗報】食塩代替品で再発リスクを14%削減。中国農村部の大規模臨床試験。カリウム塩を25%含む塩は、脳卒中の再発と死亡リスクを有意に低下させ、安全性も確認。シンプルな食事介入で健康改善の可能性JAMA Cardiology, 2025 → https://t.co/TGaXoQzKWm https://t.co/wQbJGYO1dQ

Mar 11, 2025 · 1,185 followers View post →
Saber Atualizado
@saberatualizado.bsky.social · Bluesky

(1) Publicação do estudo: Ding et al. (2025). Salt Substitution and Recurrent Stroke and Death: A Randomized Clinical Trial. JAMA Cardiology. doi.org/10.1001/jama...

Mar 10, 2025 · 6 likes View post →
Klinger Neves
@Kli_Nev · X

RT @AtualizadoSaber: (1) Publicação do estudo: Ding et al. (2025). Salt Substitution and Recurrent Stroke and Death: A Randomized Clinical…

Mar 9, 2025 · 1 share · 3,795 followers View post →
Saber Atualizado
@AtualizadoSaber · X

(1) Publicação do estudo: Ding et al. (2025). Salt Substitution and Recurrent Stroke and Death: A Randomized Clinical Trial. JAMA Cardiology. https://t.co/D4OzQzMPzF

Mar 9, 2025 · 6 likes · 1 share · 30,177 followers View post →
Shashi Agarwal, MD
@usacardiologist · X

Salt Substitutes & Recurrent Stroke (3 of 3) #health #fitness #wellness In a recent study (#15,249) with stroke, use of a salt substitute led to a 14% reduction in the risk of recurrent stroke and a 12% reduction in mortality. (JAMA Cardiol. 2025. 10.1001/jamacardio.2024.5417)

Feb 17, 2025 · 19 followers View post →
いっちー@バーチャル精神科医
@ichiipsy · X

Ding X, Zhang X, Huang L, et al. Salt Substitution and Recurrent Stroke and Death: A Randomized Clinical Trial. JAMA Cardiol. Published online February 05, 2025. doi:10.1001/jamacardio.2024.5417 https://t.co/iMX1k1mHgq

Feb 14, 2025 · 2 likes · 78,782 followers View post →
Francki
@francbarragan · X

RT @docramiro: Sustitutos de sal y riesgo de evento cerebral vascular Referencia: doi:10.1001/jamacardio.2024.5417 https://t.co/qG3leGdj19

Feb 9, 2025 · 28 shares · 111 followers View post →
Ellen Ripley Parody
@kohortenmische · X

RT @Neuro24de: https://t.co/tkxtKc9rf1

Feb 9, 2025 · 1 share · 1,437 followers View post →
Karl C. Mayer
@Neuro24de · X

https://t.co/tkxtKc9rf1

Feb 9, 2025 · 2 likes · 1 share · 1,318 followers View post →
Daniela
@lagrinningsoul · X

Odkaz na studii v JAMA Cardiology zde: https://t.co/1EGIMT33qd

Feb 9, 2025 · 2 likes · 1,497 followers View post →
ANTONIO KLLEJO
@Kllejo · X

RT @docramiro: Sustitutos de sal y riesgo de evento cerebral vascular Referencia: doi:10.1001/jamacardio.2024.5417 https://t.co/qG3leGdj19

Feb 8, 2025 · 28 shares · 156 followers View post →
Carlos Garcia
@lxDarkerxl · X

RT @docramiro: Sustitutos de sal y riesgo de evento cerebral vascular Referencia: doi:10.1001/jamacardio.2024.5417 https://t.co/qG3leGdj19

Feb 8, 2025 · 28 shares · 621 followers View post →
Rafael E. Aguirre Q.
@drlitoaguirre1 · X

RT @docramiro: Sustitutos de sal y riesgo de evento cerebral vascular Referencia: doi:10.1001/jamacardio.2024.5417 https://t.co/qG3leGdj19

Feb 8, 2025 · 28 shares · 3,073 followers View post →
carlos Pérez Gómez
@carlosPrezGmez4 · X

RT @docramiro: Sustitutos de sal y riesgo de evento cerebral vascular Referencia: doi:10.1001/jamacardio.2024.5417 https://t.co/qG3leGdj19

Feb 8, 2025 · 28 shares · 1,044 followers View post →
JACJ M.D.
@JACJ183 · X

RT @docramiro: Sustitutos de sal y riesgo de evento cerebral vascular Referencia: doi:10.1001/jamacardio.2024.5417 https://t.co/qG3leGdj19

Feb 7, 2025 · 28 shares · 1,129 followers View post →
Blanquito
@Blanquito_Amor · X

RT @docramiro: Sustitutos de sal y riesgo de evento cerebral vascular Referencia: doi:10.1001/jamacardio.2024.5417 https://t.co/qG3leGdj19

Feb 7, 2025 · 28 shares · 2,701 followers View post →
rodolfoxoliz
@rodolfoxoliz · X

RT @docramiro: Sustitutos de sal y riesgo de evento cerebral vascular Referencia: doi:10.1001/jamacardio.2024.5417 https://t.co/qG3leGdj19

Feb 7, 2025 · 28 shares · 4,464 followers View post →
Rubén
@IamRubenMejia · X

RT @docramiro: Sustitutos de sal y riesgo de evento cerebral vascular Referencia: doi:10.1001/jamacardio.2024.5417 https://t.co/qG3leGdj19

Feb 7, 2025 · 28 shares · 316 followers View post →
Ramon Rivera ☕️
@RamonRiv92 · X

RT @docramiro: Sustitutos de sal y riesgo de evento cerebral vascular Referencia: doi:10.1001/jamacardio.2024.5417 https://t.co/qG3leGdj19

Feb 7, 2025 · 28 shares · 341 followers View post →
Roberto Ortiz
@Chaputin90 · X

RT @docramiro: Sustitutos de sal y riesgo de evento cerebral vascular Referencia: doi:10.1001/jamacardio.2024.5417 https://t.co/qG3leGdj19

Feb 7, 2025 · 28 shares · 144 followers View post →
Dra. Bere d' Sanz
@BereSanzera · X

RT @docramiro: Sustitutos de sal y riesgo de evento cerebral vascular Referencia: doi:10.1001/jamacardio.2024.5417 https://t.co/qG3leGdj19

Feb 7, 2025 · 28 shares · 1,541 followers View post →
Norma
@Norma06657442 · X

RT @docramiro: Sustitutos de sal y riesgo de evento cerebral vascular Referencia: doi:10.1001/jamacardio.2024.5417 https://t.co/qG3leGdj19

Feb 7, 2025 · 28 shares · 113 followers View post →
Sergio Garcia
@sage0192 · X

RT @docramiro: Sustitutos de sal y riesgo de evento cerebral vascular Referencia: doi:10.1001/jamacardio.2024.5417 https://t.co/qG3leGdj19

Feb 7, 2025 · 28 shares · 25 followers View post →
Bati-Doc
@drluis1980 · X

RT @docramiro: Sustitutos de sal y riesgo de evento cerebral vascular Referencia: doi:10.1001/jamacardio.2024.5417 https://t.co/qG3leGdj19

Feb 7, 2025 · 28 shares · 777 followers View post →
miztli 18
@18_miztli · X

RT @docramiro: Sustitutos de sal y riesgo de evento cerebral vascular Referencia: doi:10.1001/jamacardio.2024.5417 https://t.co/qG3leGdj19

Feb 7, 2025 · 28 shares · 8 followers View post →
Eddy
@Edward_zal83 · X

RT @docramiro: Sustitutos de sal y riesgo de evento cerebral vascular Referencia: doi:10.1001/jamacardio.2024.5417 https://t.co/qG3leGdj19

Feb 7, 2025 · 28 shares · 51 followers View post →
Mega
@LilianaMega1 · X

RT @docramiro: Sustitutos de sal y riesgo de evento cerebral vascular Referencia: doi:10.1001/jamacardio.2024.5417 https://t.co/qG3leGdj19

Feb 7, 2025 · 28 shares · 2,435 followers View post →
Sofi
@CarmenSofi71305 · X

RT @docramiro: Sustitutos de sal y riesgo de evento cerebral vascular Referencia: doi:10.1001/jamacardio.2024.5417 https://t.co/qG3leGdj19

Feb 6, 2025 · 28 shares · 2,794 followers View post →
Serpri08
@serpri08 · X

RT @docramiro: Sustitutos de sal y riesgo de evento cerebral vascular Referencia: doi:10.1001/jamacardio.2024.5417 https://t.co/qG3leGdj19

Feb 6, 2025 · 28 shares · 211 followers View post →
SilviaEReyes
@exxlixxreyy · X

RT @docramiro: Sustitutos de sal y riesgo de evento cerebral vascular Referencia: doi:10.1001/jamacardio.2024.5417 https://t.co/qG3leGdj19

Feb 6, 2025 · 28 shares · 77 followers View post →
Anonimoboisex
@anonimoboisex · X

RT @docramiro: Sustitutos de sal y riesgo de evento cerebral vascular Referencia: doi:10.1001/jamacardio.2024.5417 https://t.co/qG3leGdj19

Feb 6, 2025 · 28 shares · 1,291 followers View post →
Ramiro Esparza
@docramiro · X

Sustitutos de sal y riesgo de evento cerebral vascular Referencia: doi:10.1001/jamacardio.2024.5417 https://t.co/qG3leGdj19

Feb 6, 2025 · 180 likes · 28 shares · 68,312 followers View post →
村田裕康(Hiroyasu Murata)，PT，PhD
@mrt1104 · X

塩の代替が安全であり、脳卒中の再発と死亡のリスクが低減 Salt Substitution and Recurrent Stroke and Death: A Randomized Clinical Trial https://t.co/upD6iLrZXo

Feb 6, 2025 · 5 likes · 1,206 followers View post →
Sky Health, LLC
@GotSkyHealth · X

Salt Substitution and Recurrent Stroke and Death https://t.co/8cpEHxIu5h #diet #health #stroke #hypertension #cardiovasculardisease #salt #sodium #potassium #research #Researchpaper

Feb 6, 2025 · 73 followers View post →
schnitzr
@schnitzr · X

Salt Substitution and Recurrent Stroke and Death: A Randomized Clinical Trial | Cerebrovascular Disease | JAMA Cardiology | JAMA Network https://t.co/0m9YYU6ODX

Feb 6, 2025 · 167 followers View post →
Giuseppe Biondi-Zoccai
@gbiondizoccai · X

In the Salt Substitute and Stroke Study (SSaSS), an open-label cluster randomized clinical trial including 15249 patients with stroke, salt substitution was safe and was associated with reduced risks of stroke recurrence and death https://t.co/nQXTUuHqmp @JAMACardio https://t.co/cHC4hw2xJ5

Feb 6, 2025 · 12,129 followers View post →
Un tal Carlos Rene
@nomecreaspero · X

RT @JAMA_current: From @JAMACardio: Using salt substitutes instead of regular salt reduced the rates of recurrent stroke and mortality am…

Feb 5, 2025 · 5 shares · 378 followers View post →
Pat
@Hlth_News · X

RT @JAMA_current: From @JAMACardio: Using salt substitutes instead of regular salt reduced the rates of recurrent stroke and mortality am…

Feb 5, 2025 · 5 shares · 689 followers View post →
Khanchouch Faicel
@KhanchouchFaic1 · X

RT @JAMACardio: Using salt substitutes instead of regular salt reduced the rates of recurrent stroke and mortality among patients with a hi…

Feb 5, 2025 · 3 shares · 984 followers View post →
Camillero Autodidacta
@j_dseppuku · X

RT @JAMA_current: From @JAMACardio: Using salt substitutes instead of regular salt reduced the rates of recurrent stroke and mortality am…

Feb 5, 2025 · 5 shares · 323 followers View post →
Min Seo Kim, MD, MSDH
@MinSeoKim_MD · X

RT @JAMA_current: From @JAMACardio: Using salt substitutes instead of regular salt reduced the rates of recurrent stroke and mortality am…

Feb 5, 2025 · 5 shares · 2,587 followers View post →
David de las Cuevas
@DaviddlCuevas · X

RT @JAMA_current: From @JAMACardio: Using salt substitutes instead of regular salt reduced the rates of recurrent stroke and mortality am…

Feb 5, 2025 · 5 shares · 1,400 followers View post →
Mehmet S Uyanik, MD
@Dr_MSU · X

Feb 5, 2025 · 1,659 followers View post →
JAMA
@JAMA_current · X

From @JAMACardio: Using salt substitutes instead of regular salt reduced the rates of recurrent stroke and mortality among patients with a history of stroke in rural China, without increasing the risk of hyperkalemia. https://t.co/JInUzgkDRd @MaoyiT https://t.co/vnf65GBlNt

Feb 5, 2025 · 18 likes · 5 shares · 488,081 followers View post →
Jarosław Jan Pinkas
@PinkasJJ · X

RT @JAMAInternalMed: Fom @JAMACardio: Using salt substitutes instead of regular salt reduced the rates of recurrent stroke and mortality am…

Feb 5, 2025 · 1 share · 3,050 followers View post →
JAMA
@JAMA_current · X

From @JAMACardio: Using salt substitutes instead of regular salt reduced the rates of recurrent stroke and mortality among patients with a history of stroke in rural China, without increasing the risk of hyperkalemia. https://t.co/JInUzgkDRd @MaoyiT https://t.co/jkGvbf1iEx

Feb 5, 2025 · 488,081 followers View post →
JAMA Internal Medicine
@JAMAInternalMed · X

Fom @JAMACardio: Using salt substitutes instead of regular salt reduced the rates of recurrent stroke and mortality among patients with a history of stroke in rural China, without increasing the risk of hyperkalemia. https://t.co/Oo06hrgi0W @MaoyiT https://t.co/xE4ZVr9g9i

Feb 5, 2025 · 3 likes · 1 share · 108,184 followers View post →
JAMA Neurology
@JAMANeuro · X

From @JAMACardio: Using salt substitutes instead of regular salt reduced the rates of recurrent stroke and mortality among patients with a history of stroke in rural China, without increasing the risk of hyperkalemia. https://t.co/RrBg2vnC3W @MaoyiT https://t.co/Bbzrz87HKg

Feb 5, 2025 · 9 likes · 1 share · 65,066 followers View post →
JAMA Cardiology
@JAMACardio · X

Using salt substitutes instead of regular salt reduced the rates of recurrent stroke and mortality among patients with a history of stroke in rural China, without increasing the risk of hyperkalemia. https://t.co/PaYWAQJ68T @MaoyiT https://t.co/CN3e3lGb2y

Feb 5, 2025 · 15 likes · 3 shares · 47,815 followers View post →