Integrating the environmental and genetic architectures of aging and mortality https://t.co/AoUGuL8HID
Integrating the environmental and genetic architectures of aging and mortality.
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Feb 2025 – Sep 2025Where it's discussed
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News392 articles
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X / Twitter86 posts
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Blogs10 articles
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Bluesky6 posts
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Facebook6 posts
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YouTube3 videos
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Reddit2 posts
AI synopsis
What people are saying
Discussions throughout the collection consistently reinforce the idea that environmental factors, like lifestyle choices and socioeconomic status, have a greater influence on aging and mortality than genetics—evidenced by phrases such as 'environment shapes disease patterns' and 'social drivers of health.' The tone is generally analytical and supportive, emphasizing the significance of the findings for public health and personal well-being, which supports the assessment of high impact and engagement.
Most discussions emphasize the importance of environmental factors surpassing genetics in influencing aging and mortality, showing strong support for the publication's findings.
The widespread sharing of the article across social discussions, with mentions of specific data points and implications, indicates high interest in the study.
Posts frequently reference key details such as the role of the exposome, environmental exposures, and implications for health, demonstrating deep engagement with the research.
Many comments highlight the potential for these findings to influence health strategies, policy, and personal lifestyle choices, reflecting a perception of high impact.
Abstract in brief
- Both genetics and environmental factors significantly influence aging and premature mortality, highlighted by an exposome-wide analysis of UK Biobank data involving nearly 500,000 participants.
- The study identified 25 unique environmental exposures linked to all-cause mortality and biomarker aging, revealing that these exposures have a greater impact (17%) on mortality variation than polygenic risk scores (less than 2%).
- While genetic factors have a stronger influence on specific cancers and dementias, environmental factors account for a larger share of variation in diseases related to the lungs, heart, and liver, emphasizing the complex interplay between environment and genetics in age-related health outcomes.
Top posts
Most liked on X and BlueskyA must read. Again highlighting power prospective large cohort studies, open global science & open access. Thank you @uk_biobank @wellcometrust @The_MRC Integrating the environmental and genetic architectures of aging and mortality https://t.co/EjC7dBcqFc
Integrating the environmental and genetic architectures of aging and mortality www.nature.com/articles/s41...
Integrating the environmental and genetic architectures of aging and mortality. #NatureMedicine www.nature.com/articles/s41...
Integrating the environmental and genetic architectures of aging and mortality https://t.co/3MEPdRoxQM https://t.co/JVShPDAvMZ
https://t.co/c3ThdPIyVS
All mentions
Environmental Factors Overwhelm Genetics in Aging and Mortality
Get insights from a study of nearly 500,000 people showing that environment and daily choices, like smoking and activity, impact lifespan more than genes. Discover practical tips for a healthier, longer life.
Environmental Factors Outperform Genes in Longevity and Healthy Aging
Your environment and lifestyle significantly influence health and longevity more than genetics. This video explores a Nature Medicine study showing that factors like education, income, sleep quality, and social support…
Environmental Factors Have Greater Impact on Aging Than Genes
A groundbreaking study analyzed nearly 500,000 people and found that lifestyle and environmental factors matter more than genetics when it comes to aging and mortality. Learn how 25 key exposures influence lifespan and…
Integrating the environmental and genetic architectures of aging and mortality | Nature Medicine https://t.co/Ls1nKIQ87N
Nature vs. Nurture...thats Genetics vs. Your Environment. This UK Biobank study with 500,000 participants identified 25 environmental exposures linked to aging, mortality, and common diseases. Integrating the environmental and genetic architectures of aging and mortality. Nat
https://t.co/c3ThdPIyVS
加齢に関連した疾患の発症と死亡について遺伝子よりもライフスタイルが重要ということで話題になったIntegrating the environmental and genetic architectures of aging and mortalityを研究室のジャーナルクラブで取り上げることにしました. https://t.co/FKYXMloCWm ご興味があればご一報ください.
WHAT MATTERS MORE: - YOUR DNA OR ENVIRONMENT Secret of Longevity A Summary of “Integrating the Environmental and Genetic Architectures of Aging and Mortality" by M. Austin Argentieri et. al. Nature Medicine (2025)” Dr. Pramod Pandey https://t.co/ACgsRGGw9a
Integrating the environmental and genetic architectures of aging and mortality | Nature Medicine https://t.co/HlnSK0Jxc7
Integrating the environmental and genetic architectures of aging and mortality | Nature Medicine “The #exposome shapes distinct patterns of disease and mortality risk, irrespective of polygenic disease risk” https://t.co/aL4beX2UGt
Integrating the environmental and genetic architectures of aging and mortality | Nature Medicine https://t.co/tqo0HQFowf
Más información: Argentieri, M.A., Amin, N., Nevado-Holgado, A.J. et al. Integrating the environmental and genetic architectures of aging and mortality. Nat Med 31, 1016–1025 (2025). https://t.co/meZkrCXE3n
¡Descubre cómo tu entorno supera a tus genes en la longevidad!
Integrating the environmental and genetic architectures of aging and mortality https://t.co/xfkAQlzkaS
Integrating the environmental and genetic architectures of aging and mortality | Nature Medicine https://t.co/pQGkSgb5SD
Integrating the environmental and genetic architectures of aging and mortality. https://t.co/ZWe0o1MjKl
RT @masayuki_umeda_: Integrating the environmental and genetic architectures of aging and mortality | Nature Medicine https://t.co/xPv2bVPL…
Integrating the environmental and genetic architectures of aging and mortality | Nature Medicine https://t.co/xPv2bVPLyI
@BrandonLuuMD Argentieri, M. A., Amin, N., Nevado-Holgado, A. J., Sproviero, W., Collister, J. A., Keestra, S. M., ... & van Duijn, C. M. (2025). Integrating the environmental and genetic architectures of aging and mortality. Nature Medicine, 1-10. https://t.co/pbbx8zLJXF
What do you think?
2025年2月发表的《Integrating the environmental and genetic architectures of aging and mortality》。这项研究整合了环境因素和遗传因素,分析了它们如何共同塑造人类的衰老过程和死亡风险。
RT @WHOCenterFrailt: Identifying 25 independent exposures "Integrating the environmental and genetic architectures of aging and mortality."…
How long will you live? New evidence says it’s much more about your choices than your genes | The Conversation theconversation.com/how-long-wil... Integrating the environmental and genetic architectures of aging and mortality | Nature Medicine www.nature.com/articles/s41... #openaccess
Identifier 25 risques indépendants "Integrating the environmental and genetic architectures of aging and mortality." https://t.co/MxEJxnPcwL @brunovellas @SoutoPhilipe
Identifying 25 independent exposures "Integrating the environmental and genetic architectures of aging and mortality." https://t.co/5gfk7nHgWI @brunovellas @RollandYves2
RT @JunhaoWen: Integrating the environmental and genetic architectures of aging and mortality https://t.co/ot1n4YGLcS
RT @agingdoc1: Integrating the environmental and genetic architectures of aging and mortality
RT @SciencNews: Integrating the environmental and genetic architectures of aging and mortality. #NatureMedicine https://t.co/dCnxkcz0kS ht…
Integrating the environmental and genetic architectures of aging and mortality. #NatureMedicine https://t.co/dCnxkcz0kS https://t.co/IuSUYXfQl6
Integrating the environmental and genetic architectures of aging and mortality. #NatureMedicine www.nature.com/articles/s41...
Integrating the environmental and genetic architectures of aging and mortality https://t.co/7groUmrArH
RT @K9FCR: Integrating the environmental and genetic architectures of aging and mortality | Nature Medicine https://t.co/xmCsVpd1uP
Integrating the environmental and genetic architectures of aging and mortality | Nature Medicine https://t.co/xmCsVpd1uP
“Integrating the environmental and genetic architectures of aging and mortality.” https://t.co/6AUTL4S7gI
RT @AndresFCardonaZ: Integrating the environmental and genetic architectures of aging and mortality https://t.co/8qukg5TIxx
RT @AndresFCardonaZ: Integrating the environmental and genetic architectures of aging and mortality https://t.co/8qukg5TIxx
Integrating the environmental and genetic architectures of aging and mortality https://t.co/8qukg5TIxx
El artículo “Integrating the environmental and genetic architectures of aging and mortality”, publicado en Nature Medicine, analiza cómo el ambiente (exposoma) y la genética contribuyen al envejecimiento y la mortalidad. https://t.co/S3hYiBgwef
Integrating the environmental and genetic architectures of aging and mortality
RT @isciverse: Integrating the environmental and genetic architectures of aging and mortality https://t.co/3MEPdRoxQM https://t.co/JVShPDA…
RT @isciverse: Integrating the environmental and genetic architectures of aging and mortality https://t.co/3MEPdRoxQM https://t.co/JVShPDA…
Integrating the environmental and genetic architectures of aging and mortality https://t.co/zbcsZSE2R5
RT @isciverse: Integrating the environmental and genetic architectures of aging and mortality https://t.co/3MEPdRoxQM https://t.co/JVShPDA…
RT @isciverse: Integrating the environmental and genetic architectures of aging and mortality https://t.co/3MEPdRoxQM https://t.co/JVShPDA…
RT @isciverse: Integrating the environmental and genetic architectures of aging and mortality https://t.co/3MEPdRoxQM https://t.co/JVShPDA…
RT @isciverse: Integrating the environmental and genetic architectures of aging and mortality https://t.co/3MEPdRoxQM https://t.co/JVShPDA…
Integrating the environmental and genetic architectures of aging and mortality https://t.co/3MEPdRoxQM https://t.co/JVShPDAvMZ
Integrating the environmental and genetic architectures of aging and mortality www.nature.com/articles/s41...
RT @JeremyFarrar: A must read. Again highlighting power prospective large cohort studies, open global science & open access. Thank you @u…
@theliverdr Found the Paper: Integrating the environmental and genetic architectures of aging and mortality | Nature Medicine https://t.co/sOPaPM3MXd
Integrating the environmental and genetic architectures of aging and mortality https://t.co/xfkAQlzkaS
Interesting paper published in Nature Medicine from M. Austin Argentieri on 'Integrating the environmental and genetic architectures of aging and mortality'
RT @JeremyFarrar: A must read. Again highlighting power prospective large cohort studies, open global science & open access. Thank you @u…
Integrating the environmental and genetic architectures of aging and mortality | Nature Medicine https://t.co/HlnSK0Jxc7
RT @daniel_kraft: From @Nature paper Integrating the environmental and genetic architectures of aging and mortality https://t.co/i1riCKt…
From @Nature paper Integrating the environmental and genetic architectures of aging and mortality https://t.co/i1riCKtQ1i
RT @GlobalPHObserv: Integrating the environmental and genetic architectures of aging and mortality | Nature Medicine https://t.co/HtlUe6BtP0
RT @GlobalPHObserv: Integrating the environmental and genetic architectures of aging and mortality | Nature Medicine https://t.co/HtlUe6BtP0
RT @GlobalPHObserv: Integrating the environmental and genetic architectures of aging and mortality | Nature Medicine https://t.co/HtlUe6BtP0
Integrating the environmental and genetic architectures of aging and mortality https://t.co/P1T2lVo0d0 https://t.co/OiSqoypVkt
Integrating the environmental and genetic architectures of aging and mortality | Nature Medicine https://t.co/HtlUe6BtP0
Integrating the environmental and genetic architectures of aging and mortality | Nature Medicine https://t.co/mmaUItXNWA
A must read. Again highlighting power prospective large cohort studies, open global science & open access. Thank you @uk_biobank @wellcometrust @The_MRC Integrating the environmental and genetic architectures of aging and mortality https://t.co/EjC7dBcqFc
Integrating the environmental and genetic architectures of aging and mortality https://t.co/tldGAprlwL
Integrating the environmental and genetic architectures of aging and mortality https://t.co/ZWe0o1MjKl
Integrating the environmental and genetic architectures of aging and mortality | Nature Medicine https://t.co/uV4mvm0fyl
Integrating the environmental and genetic architectures of aging and mortality | Nature Medicine https://t.co/uV4mvm0fyl
Integrating the environmental and genetic architectures of aging and mortality https://t.co/yhBOTtku5s
RT @TimePieChina: Environmental factors, lifestyle choices have greater impact on health than genes, a new study published on @NatureMedici…
RT @DrFAlzaid: Latest curated papers
Integrating the environmental and genetic architectures of aging and mortality https://t.co/ZWe0o1MjKl
Latest curated papers
RT @StephenPiment: Integrating the environmental and genetic architectures of aging and mortality Environmental factors have a far greater…
Integrating the environmental and genetic architectures of aging and mortality Environmental factors have a far greater impact on premature mortality and aging than genetic predisposition, with smoking, socioeconomic status, physical activity, sleep, and mental well-being
元論文→ Reference: Argentieri MA, Amin N, Nevado-Holgado AJ, et al. Integrating the environmental and genetic architectures of aging and mortality. Nat Med. 2025. doi: 10.1038/s41591-024-03483-9 https://t.co/7sk8MiKwE2
Integrating the environmental and genetic architectures of aging and mortality | Nature Medicine https://t.co/udj5CinJzj
Integrating the environmental and genetic architectures of aging and mortality https://t.co/xfkAQlzS0q
Integrating the environmental and genetic architectures of aging and mortality | Nature Medicine https://t.co/0MPouPcqXz
Further evidence that environment (aka, social drivers of health #SDOH)) has greater influence on health than #genetic code...#health #healthcare #Medsky Integrating the environmental and genetic architectures of #aging and #mortality. Nat Med (2025) www.nature.com/articles/s41...
RT @AgingBiology: Integrating the environmental and genetic architectures of aging and mortality https://t.co/AoUGuL8HID
Integrating the environmental and genetic architectures of aging and mortality | Nature Medicine https://t.co/KUp9jKGunZ
Integrating the environmental and genetic architectures of aging and mortality | Nature Medicine https://t.co/atzB493iQf
RT @JunhaoWen: Integrating the environmental and genetic architectures of aging and mortality https://t.co/ot1n4YGLcS
RT @AgingBiology: Integrating the environmental and genetic architectures of aging and mortality https://t.co/AoUGuL8HID
Environmental factors, lifestyle choices have greater impact on health than genes, a new study published on @NatureMedicine finds. #aging By @austinargen, @AlexAlvergne, @NajafAmin, @aiden1doherty, et al. https://t.co/PJg2uacVqN https://t.co/LUtbji6Ays
Integrating the environmental and genetic architectures of aging and mortality https://t.co/VdApr25S9D https://t.co/vsiZD8iFqT
NATURE / Integrating the environmental and genetic architectures of #aging and mortality #yaşlanma #genetik #winally #eksposom https://t.co/Yo4paWvo9y
RT @AgingBiology: Integrating the environmental and genetic architectures of aging and mortality https://t.co/AoUGuL8HID
RT @AgingBiology: Integrating the environmental and genetic architectures of aging and mortality https://t.co/AoUGuL8HID
Integrating the environmental and genetic architectures of aging and mortality | Nature Medicine look around - what you eat, were and how you live - it is matter… https://t.co/NdYYneAabQ
RT @AgingBiology: Integrating the environmental and genetic architectures of aging and mortality https://t.co/AoUGuL8HID
Integrating the environmental and genetic architectures of aging and mortality https://t.co/AoUGuL8HID
Open access study here: "The exposome shapes distinct patterns of disease & mortality risk, irrespective of polygenic disease risk." Integrating the environmental and genetic architectures of aging and mortality
“Integrating the #environmental and #genetic architectures of #aging and #mortality | Nature Medicine.”
Integrating the environmental and genetic architectures of aging and mortality https://t.co/ot1n4YGLcS
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