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Several discussions include words of praise like 'Nice work' and expressions of anticipation for research shows, indicating that participants view the study as important and promising. The tone and choice of words suggest excitement about the potential for propranolol to decrease sedative use, and references to upcoming conferences and future trials highlight perceived significance and relevance of the research to clinical practice.
Many posts express support or positive acknowledgment of the research, such as phrases like 'Nice work' and 'propranolol for the win,' indicating general agreement with the potential benefits highlighted in the publication.
The discussions demonstrate high interest, with multiple posts sharing excitement for upcoming research presentations and findings, reflecting curiosity about the implications of the study.
The social discussions show deep engagement, as posters reference specific trial outcomes, suggest clinical relevance, and highlight related ongoing research, signaling thoughtful consideration.
Participants perceive the publication as having moderate impact, pointing out potential shifts in clinical practice and the importance of the findings, though some posts remain optimistic rather than definitive.
高用量鎮静薬を要するレスピ患者で、プロプラノロール20～60mgの6時間毎の漸増投与は、鎮静薬必要性を低下させて目標鎮静を達成し、安価で、限られた鎮静薬の供給量を維持するのに役立つ可能性あり、というRCT。 有害事象のリスクは明らかな増加もなしと 今後の研究に期待 https://t.co/dAPl9061Cc
Propranolol As an Anxiolytic to Reduce the Use of Sedatives ... : Critical Care Medicine https://t.co/VVKbSfVKMY.
Propranolol As an Anxiolytic to Reduce the Use of Sedatives ... : Critical Care Medicine https://t.co/u9birYmjVD Nice work @jamesdownar
Oh, look…propranolol for the win. Again. In this small RCT, scheduled PO propranolol ⬇️ propofol and midazolam requirements/dosing & its use had more RASS at
Propranolol As an Anxiolytic to Reduce the Use of Sedatives for Critically Ill Adults Receiving Mechanical Ventilation (PROACTIVE): An Open-Label Randomized Controlled Trial https://t.co/pmKboQ5dud #icurehab #A2Fbundle
#CPPPLU Highlights
The PROACTIVE trial tested whether propranolol, a nonselective beta-blocker, can reduce sedative needs in ventilated critically ill patients, showing significant reductions without increased adverse events, potentially…
This study tested whether propranolol, a nonselective beta-blocker, could reduce sedative requirements for critically ill patients on mechanical ventilation. Results indicate it effectively decreases sedative use…
Propranolol As an Anxiolytic to Reduce the Use of Sedatives for Critically III Adults Receiving Mechanical Ventilation (PROACTIVE): An Open-Label Randomized Controlled Trial #isccm #esicm
Propranolol As an Anxiolytic to Reduce the Use of Sedatives for Critically III Adults Receiving Mechanical Ventilation (PROACTIVE): An Open-Label Randomized Controlled Trial #isccm #esicm #webinar
RT @icurehab: Propranolol As an Anxiolytic to Reduce the Use of Sedatives for Critically Ill Adults Receiving Mechanical Ventilation (PROAC…
RT @icurehab: Propranolol As an Anxiolytic to Reduce the Use of Sedatives for Critically Ill Adults Receiving Mechanical Ventilation (PROAC…
RT @icurehab: Propranolol As an Anxiolytic to Reduce the Use of Sedatives for Critically Ill Adults Receiving Mechanical Ventilation (PROAC…
Propranolol As an Anxiolytic to Reduce the Use of Sedatives for Critically Ill Adults Receiving Mechanical Ventilation (PROACTIVE): An Open-Label Randomized Controlled Trial https://t.co/pmKboQ5dud #icurehab #A2Fbundle
RT @gdomeni: Propranolol As an Anxiolytic to Reduce the Use of Sedatives ... : Critical Care Medicine https://t.co/VVKbSfVKMY.
RT @gdomeni: Propranolol As an Anxiolytic to Reduce the Use of Sedatives ... : Critical Care Medicine https://t.co/VVKbSfVKMY.
RT @gdomeni: Propranolol As an Anxiolytic to Reduce the Use of Sedatives ... : Critical Care Medicine https://t.co/VVKbSfVKMY.
RT @gdomeni: Propranolol As an Anxiolytic to Reduce the Use of Sedatives ... : Critical Care Medicine https://t.co/VVKbSfVKMY.
Propranolol As an Anxiolytic to Reduce the Use of Sedatives ... : Critical Care Medicine https://t.co/VVKbSfVKMY.
#CPPPLU Highlights
プロプラノール投与で、鎮静薬の減量が可能か？ →明らかな有害事象の増加なしに、有意な鎮静薬の減量が可能であった。 （非盲検、3施設RCT、解析対象29人vs28人） 若年の方などで、鎮静に難渋する場合にはプロプラノールの投与を検討する価値はあるかもしれませんね。 https://t.co/CS6mq4mD5g
@SCCM @memorialhermann @NEJM @UMMC #SCCMJC #PharmICU Presenter 3: Angela Castro, PharmD PGY2 CC Resident @UCSDHealth Propranolol As an Anxiolytic to Reduce the Use of Sedatives for Critically Ill Adults Receiving Mechanical Ventilation (PROACTIVE) @CritCareMed https://t.co/wFYGQAutGV
@SCCM @memorialhermann @NEJM @UMMC #SCCMJC #PharmICU Presenter 3: Angela Castro, PharmD PGY2 CC Resident @UCSDHealth Propranolol As an Anxiolytic to Reduce the Use of Sedatives for Critically Ill Adults Receiving Mechanical Ventilation (PROACTIVE) @CritCareMed https://t.co/wFYGQAtVRn
RT @pinacol: 【RCT】高用量の鎮静薬を要する人工呼吸器を装着した麻痺のない患者へのプロプラノロールの経腸投与は、通常のケアのみと比較して、鎮静薬の投与量を減少させた。 #ペ読 https://t.co/bpR3Ec6Fke
【RCT】高用量の鎮静薬を要する人工呼吸器を装着した麻痺のない患者へのプロプラノロールの経腸投与は、通常のケアのみと比較して、鎮静薬の投与量を減少させた。 #ペ読 https://t.co/bpR3Ec6Fke
RT @lessismoreicu: 高用量鎮静薬を要するレスピ患者で、プロプラノロール20～60mgの6時間毎の漸増投与は、鎮静薬必要性を低下させて目標鎮静を達成し、安価で、限られた鎮静薬の供給量を維持するのに役立つ可能性あり、というRCT。 有害事象のリスクは明らかな増加…
RT @lessismoreicu: 高用量鎮静薬を要するレスピ患者で、プロプラノロール20～60mgの6時間毎の漸増投与は、鎮静薬必要性を低下させて目標鎮静を達成し、安価で、限られた鎮静薬の供給量を維持するのに役立つ可能性あり、というRCT。 有害事象のリスクは明らかな増加…
RT @lessismoreicu: 高用量鎮静薬を要するレスピ患者で、プロプラノロール20～60mgの6時間毎の漸増投与は、鎮静薬必要性を低下させて目標鎮静を達成し、安価で、限られた鎮静薬の供給量を維持するのに役立つ可能性あり、というRCT。 有害事象のリスクは明らかな増加…
RT @lessismoreicu: 高用量鎮静薬を要するレスピ患者で、プロプラノロール20～60mgの6時間毎の漸増投与は、鎮静薬必要性を低下させて目標鎮静を達成し、安価で、限られた鎮静薬の供給量を維持するのに役立つ可能性あり、というRCT。 有害事象のリスクは明らかな増加…
高用量鎮静薬を要するレスピ患者で、プロプラノロール20～60mgの6時間毎の漸増投与は、鎮静薬必要性を低下させて目標鎮静を達成し、安価で、限られた鎮静薬の供給量を維持するのに役立つ可能性あり、というRCT。 有害事象のリスクは明らかな増加もなしと 今後の研究に期待 https://t.co/dAPl9061Cc
RT @kwadwo777: Propranolol As an Anxiolytic to Reduce the Use of Sedatives ... : Critical Care Medicine https://t.co/u9birYmjVD Nice work…
Oh, look…propranolol for the win. Again. In this small RCT, scheduled PO propranolol ⬇️ propofol and midazolam requirements/dosing & its use had more RASS at
RT @kwadwo777: Propranolol As an Anxiolytic to Reduce the Use of Sedatives ... : Critical Care Medicine https://t.co/u9birYmjVD Nice work…
Propranolol As an Anxiolytic to Reduce the Use of Sedatives ... : Critical Care Medicine https://t.co/u9birYmjVD Nice work @jamesdownar
Get a sneak peek at the critical care research you’ll find at #SCCM2025! Critical Care Medicine editors and SCCM Discovery leadership discuss a new clinical trial on aspirin treatment in patients with #sepsis and septic shock: https://t.co/BpkrehqPtB #SCCM #CritCareMed @SCCM https://t.co/ZuaopLGXeM
#clinicaltrial Propranolol as an Anxiolytic to Reduce the Use of Sedatives From Critically-ill Adults Receiving Mechanical Ventilation https://t.co/zocxnE8le4
Propranolol as an Anxiolytic to Reduce the Use of Sedatives From Critically-ill Adults Receiving Mechanical Ventilation: Status: Not yet recruiting, Condition Summary: Mechanical Ventilation; Sedation; Critical Illness; COVID https://t.co/IkZFDDS9WV