PubHawk
Crit Care Med February 2025 PMID 39982179

Acetylsalicylic Acid Treatment in Patients With Sepsis and Septic Shock: A Phase 2, Placebo-Controlled, Randomized Clinical Trial.

Thiago M L Almeida, Flávio G R Freitas, Rodrigo C Figueiredo, Sandra G Houly, Luciano C P Azevedo, Alexandre B Cavalcanti, Lucas P Damiani, Bianca S Svicero, Maria A Souza, Cíntia L S Bustamante, Fernando J S Ramos, Rafael S V Alves, Fernanda C Atallah, Míriam Jackiu, Eduardo S Pacheco

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Mentions

4
Peak: 1 in Feb 2025
across 2 sources since Feb 2025

Extended reach

4,776
potential audience

Total likes

57

Video views

2,460

Mentions per month

Feb 2025 – Sep 2025

Where it's discussed

  • X / Twitter2 posts
  • YouTube2 videos

AI synopsis

What people are saying

The overall sentiment reflects a dismissive tone, with remarks like 'lol' and references to past unreproducible studies, suggesting skepticism rather than engagement or agreement. The tone and choice of words highlight a lack of seriousness and minimal impact on current scientific discourse.

AgreementLow agreement

The first post dismisses the findings with sarcasm, indicating disagreement, while the second seems skeptical about the reliability of past trials, showing overall cautious or dismissive attitudes.

InterestNeutral interest

The comments show limited curiosity; the first dismisses the topic with humor and the second references broad research skepticism without exploring details.

EngagementLow engagement

Both posts are brief and somewhat dismissive, indicating low depth of engagement with the scientific content.

ImpactNeutral impact

The discussions do not suggest a significant influence on opinions or practices, mainly referencing skepticism and humor rather than new insights.

Abstract in brief

  • The study tested whether giving aspirin (ASA) to septic patients would help reduce organ failure, but it was stopped early because of increased bleeding risks in the aspirin group.
  • There was no significant difference in the improvement of organ function (measured by SOFA scores) between patients who received aspirin and those who got a placebo.
  • Patients taking aspirin experienced more serious side effects, especially major bleeding events, indicating that aspirin may be unsafe for septic patients in this context.
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Top posts

Most liked on X and Bluesky
Lawrence Lynn
@PatientStormDoc · X

@RWJE_BA @raj_mehta @5_utr lol. Tell that to the transfused RCT participants. https://t.co/8ygkgZkZKR

Sep 6, 2025 · 1 like · 1,158 followers View post →
Lawrence Lynn
@PatientStormDoc · X

This is the standard PettyBone RCT in critical care taught to South America and enabled by the taskforce guessed threshold set for triage No need to diagnose a single disease. They have not been reproducible for 35 years. https://t.co/8ygkgZkrVj

Jun 29, 2025 · 1,158 followers View post →

All mentions

Lawrence Lynn
@PatientStormDoc · X

@RWJE_BA @raj_mehta @5_utr lol. Tell that to the transfused RCT participants. https://t.co/8ygkgZkZKR

Sep 6, 2025 · 1 like · 1,158 followers View post →
Lawrence Lynn
@PatientStormDoc · X

This is the standard PettyBone RCT in critical care taught to South America and enabled by the taskforce guessed threshold set for triage No need to diagnose a single disease. They have not been reproducible for 35 years. https://t.co/8ygkgZkrVj

Jun 29, 2025 · 1,158 followers View post →