BMC Med February 2025 PMID 39994788

Antidepressant use and cognitive decline in patients with dementia: a national cohort study.

Minjia Mo, Tamar Abzhandadze, Minh Tuan Hoang, Simona Sacuiu, Pol Grau Jurado, Joana B Pereira, Luana Naia, Julianna Kele, Silvia Maioli, Hong Xu, Maria Eriksdotter, Sara Garcia-Ptacek

Mentions

320
Peak: 51 in Mar 2025
across 7 sources since Feb 2025

Extended reach

2,049,529
potential audience

Total likes

1,041

Video views

13,614

Mentions per month

Feb 2025 – Nov 2025

Where it's discussed

  • News156 articles
  • X / Twitter140 posts
  • Blogs8 articles
  • Bluesky5 posts
  • YouTube4 videos
  • Reddit4 posts
  • Facebook3 posts

AI synopsis

What people are saying

The group of social discussions demonstrates strong support and interest in the study's findings, as evidenced by phrases like 'raises questions about current practices' and 'faster cognitive decline linked to antidepressant use.' The tone is serious and investigative, with many posts referencing specific drugs (e.g., SSRIs, sertraline) and emphasizing the importance of personalized treatment, reflecting their deep engagement and recognition of the potential high impact on healthcare approaches.

AgreementStrong agreement

Most discussions express support or acknowledgment of the study's findings that antidepressants may accelerate cognitive decline in dementia patients.

InterestHigh interest

There is high interest, with many posts emphasizing the potential risks and prompting re-evaluations of current treatment practices.

EngagementHigh engagement

Posts show deep engagement through references to specific research details, implications for medical care, and calls for cautious use of antidepressants.

ImpactHigh impact

The discussions highlight a significant impact on medical understanding and clinical practice, with implications for treatment guidelines and patient safety.

Abstract in brief

  • The study investigates how antidepressant use affects cognitive decline, fractures, and mortality in patients with dementia, finding that certain antidepressants can worsen cognitive function.
  • Involving 18,740 dementia patients, the research highlights that 22.8% used antidepressants, primarily SSRIs, with findings showing a significant and accelerated cognitive decline linked to these medications.
  • The results indicate a stronger negative impact on cognitive function for specific drugs like sertraline and escitalopram, especially in patients with severe dementia, prompting concerns about the use of these antidepressants.

Top posts

Most liked on X and Bluesky
Dr Joanna Moncrieff
@joannamoncrieff · X

This study is important because although effects were small, they were independent of depression and there was a dose effect. It showed increased risk of cognitive decline, death and fractures was associated with antidepressant use in people with dementia https://t.co/7fwpU6P9mC https://t.co/XfvNqRzb9d

Mar 21, 2025 · 84 likes · 30 shares · 27,506 followers View post →
SILVANO TROTTA OFFICIEL
@silvano_trotta · X

L'étude : https://t.co/Tkwi0sHhnf

Jul 2, 2025 · 60 likes · 15 shares · 259,020 followers View post →
Saeed Doroudiani, MSc/PhD, PEng
@SaeedDoroudiani · X

current antidepressant use was associated with faster cognitive decline higher dispensed doses of SSRIs were associated with higher risk for severe dementia, fractures, and all-cause mortality #drugs #psychiatry #depression #dementia #brain #cognitive https://t.co/UycDWFbNiz

May 21, 2025 · 22 likes · 11 shares · 925 followers View post →
Steven Phillips, MD
@StevePhillipsMD · X

Recent study: SSRI's (antidepressants) associated with dementia. Even worse: A dose response curve was seen. Higher doses associated with increased dementia, fractures, & death. Dose response curves are usually meaningful in such studies. https://t.co/kl0SG35JdM

Apr 2, 2025 · 15 likes · 7 shares · 82,892 followers View post →
Kiinalainen_kaali_potti2
@KaaliPotti2 · X

_φ(・_・ 一部の抗うつ薬「SSRI」は認知症患者の知能低下を加速させる可能性がある https://t.co/U0DDkUKqkb 抗うつ薬の使用と認知症患者の認知機能低下 https://t.co/Qvq9E7ks3U https://t.co/uijG1PVUBO https://t.co/y4RmEZgemi

Jul 18, 2025 · 13 likes · 6 shares · 361 followers View post →
Online Pharmacy
@PharmacyOnline8 · X

Feb 27, 2025 · 10 likes · 5 shares · 6,260 followers View post →

All mentions

DumbedDownTV
@Dumbed_DownTV · X

RT @DrEvgenyLegedin: I hope that the UCL professor who uses depression

Nov 15, 2025 · 56 shares · 900 followers View post →
UltimApe
@ultimape · X

@markeatsmeat It's worth studying if your'e interested in neurodegenerative diseases & the impact of SSRIs on brain problems. "However, older adults with depression receiving SSRIs/SNRIs were associated with an increased risk of dementia compared to psychotherapy" https://t.co/LTSUnWIgMQ

Nov 5, 2025 · 6,755 followers View post →
PSSD and PFS sufferer
@gardentimeline · X

RT @DrEvgenyLegedin: I hope that the UCL professor who uses depression

Oct 29, 2025 · 56 shares · 281 followers View post →
Alyne Duthie
@DuthieAlyne · X

RT @DrEvgenyLegedin: I hope that the UCL professor who uses depression

Oct 29, 2025 · 56 shares · 1,918 followers View post →
recovery&renewal
@recover2renew · X

RT @DrEvgenyLegedin: I hope that the UCL professor who uses depression

Oct 29, 2025 · 56 shares · 4,165 followers View post →
jorge ♂️
@Lomus_ · X

RT @DrEvgenyLegedin: I hope that the UCL professor who uses depression

Oct 28, 2025 · 56 shares · 321 followers View post →
Dr Evgeny Legedin
@DrEvgenyLegedin · X

RT @DrEvgenyLegedin: I hope that the UCL professor who uses depression

Oct 28, 2025 · 56 shares · 5,239 followers View post →
Hans Bangen - Psychiatrie / Psychiatry
@HansBangen · X

RT @DrEvgenyLegedin: I hope that the UCL professor who uses depression

Oct 23, 2025 · 56 shares · 159 followers View post →
Radoslaw Stupak
@RadoslawStupak · X

RT @DrEvgenyLegedin: I hope that the UCL professor who uses depression

Oct 23, 2025 · 56 shares · 1,184 followers View post →
Altamiro Bottino
@BottinoAltamiro · X

Antidepressant use and cognitive decline in patients with dementia: a national cohort study https://t.co/k0vKvKjFmw https://t.co/Dvjfien22e

Sep 6, 2025 · 93 followers View post →
Sara Punket
@sarapunk7 · X

RT @DrEvgenyLegedin: I hope that the UCL professor who uses depression

Sep 2, 2025 · 51 shares · 763 followers View post →
Glenna Demeter
@Glennademeter · X

RT @DrEvgenyLegedin: I hope that the UCL professor who uses depression

Sep 1, 2025 · 51 shares · 3,409 followers View post →
Lou Lou
@Louthewarrior · X

RT @DrEvgenyLegedin: I hope that the UCL professor who uses depression

Sep 1, 2025 · 51 shares · 1,789 followers View post →
La Double Vie
@Onbodyandsoul · X

RT @DrEvgenyLegedin: I hope that the UCL professor who uses depression

Sep 1, 2025 · 51 shares · 1,085 followers View post →
io
@kilnerevonnet · X

RT @DrEvgenyLegedin: I hope that the UCL professor who uses depression

Sep 1, 2025 · 51 shares · 692 followers View post →
‎dana scully's red hair
@danascullyshair · X

RT @DrEvgenyLegedin: I hope that the UCL professor who uses depression

Sep 1, 2025 · 56 shares · 1,136 followers View post →
JRO
@CausalSocial · X

RT @DrEvgenyLegedin: I hope that the UCL professor who uses depression

Sep 1, 2025 · 51 shares · 21 followers View post →
Jayne Kennedy
@JayneKenne45941 · X

RT @DrEvgenyLegedin: I hope that the UCL professor who uses depression

Sep 1, 2025 · 51 shares · 19 followers View post →
Dr Evgeny Legedin
@DrEvgenyLegedin · X

RT @DrEvgenyLegedin: I hope that the UCL professor who uses depression

Sep 1, 2025 · 51 shares · 5,235 followers View post →
Patientmakt
@PatientCV · X

New Swedish research shows that the use of antidepressants in dementia is linked to faster cognitive decline. The results raise questions about current treatment practices. https://t.co/9M0I9RUXb4 @Demensforbundet

Jul 22, 2025 · 1 like · 1,926 followers View post →
neko2koban090
@neko2koban090 · X

RT @KaaliPotti2: _φ(・_・ 一部の抗うつ薬「SSRI」は認知症患者の知能低下を加速させる可能性がある https://t.co/U0DDkUKqkb 抗うつ薬の使用と認知症患者の認知機能低下 https://t.co/Qvq9E7ks3U https:/…

Jul 19, 2025 · 6 shares · 72 followers View post →
Tabatha
@araran100 · X

RT @KaaliPotti2: _φ(・_・ 一部の抗うつ薬「SSRI」は認知症患者の知能低下を加速させる可能性がある https://t.co/U0DDkUKqkb 抗うつ薬の使用と認知症患者の認知機能低下 https://t.co/Qvq9E7ks3U https:/…

Jul 19, 2025 · 6 shares · 17,565 followers View post →
沢 野 水 樹
@Mizu_ki_Sa_wano · X

RT @KaaliPotti2: _φ(・_・ 一部の抗うつ薬「SSRI」は認知症患者の知能低下を加速させる可能性がある https://t.co/U0DDkUKqkb 抗うつ薬の使用と認知症患者の認知機能低下 https://t.co/Qvq9E7ks3U https:/…

Jul 19, 2025 · 6 shares · 1,575 followers View post →
シナモンティ
@VHnEe4zitoizXFQ · X

RT @KaaliPotti2: _φ(・_・ 一部の抗うつ薬「SSRI」は認知症患者の知能低下を加速させる可能性がある https://t.co/U0DDkUKqkb 抗うつ薬の使用と認知症患者の認知機能低下 https://t.co/Qvq9E7ks3U https:/…

Jul 19, 2025 · 6 shares · 1,287 followers View post →
Hirokazu
@hirokazupapi · X

RT @KaaliPotti2: _φ(・_・ 一部の抗うつ薬「SSRI」は認知症患者の知能低下を加速させる可能性がある https://t.co/U0DDkUKqkb 抗うつ薬の使用と認知症患者の認知機能低下 https://t.co/Qvq9E7ks3U https:/…

Jul 19, 2025 · 6 shares · 48,082 followers View post →
喜世
@8A5S20yQU6SCT8Y · X

RT @KaaliPotti2: _φ(・_・ 一部の抗うつ薬「SSRI」は認知症患者の知能低下を加速させる可能性がある https://t.co/U0DDkUKqkb 抗うつ薬の使用と認知症患者の認知機能低下 https://t.co/Qvq9E7ks3U https:/…

Jul 18, 2025 · 6 shares · 1,137 followers View post →
Kiinalainen_kaali_potti2
@KaaliPotti2 · X

_φ(・_・ 一部の抗うつ薬「SSRI」は認知症患者の知能低下を加速させる可能性がある https://t.co/U0DDkUKqkb 抗うつ薬の使用と認知症患者の認知機能低下 https://t.co/Qvq9E7ks3U https://t.co/uijG1PVUBO https://t.co/y4RmEZgemi

Jul 18, 2025 · 13 likes · 6 shares · 361 followers View post →
Tilt
@tilt66 · X

@ray5ar @incredule_Ath @hopla_staub Aucune étude (qui ne soit pas réfutée) ne démontre une perte de QI à cause du Cannabis. Les SSRIs ne sont pas anodins non plus. https://t.co/C83THsV75B https://t.co/I2mfiiqTO9 https://t.co/N4gLoyc0mj https://t.co/o0o97MaB5c https://t.co/gKgy9sUZ2n

Jul 13, 2025 · 267 followers View post →
Karine Hamelin
@KarineH441 · X

RT @silvano_trotta: L'étude : https://t.co/Tkwi0sHhnf

Jul 3, 2025 · 15 shares · 619 followers View post →
colère
@CazMariani · X

RT @silvano_trotta: L'étude : https://t.co/Tkwi0sHhnf

Jul 3, 2025 · 15 shares · 7,372 followers View post →
LOUICET Frantz
@LouicetF · X

RT @silvano_trotta: L'étude : https://t.co/Tkwi0sHhnf

Jul 3, 2025 · 15 shares · 352 followers View post →
justicier matricule 252
@bo_chart · X

RT @silvano_trotta: L'étude : https://t.co/Tkwi0sHhnf

Jul 3, 2025 · 15 shares · 12,716 followers View post →
Fabrice Stock
@sto73735 · X

RT @silvano_trotta: L'étude : https://t.co/Tkwi0sHhnf

Jul 3, 2025 · 15 shares · 299 followers View post →
xavier chataigner
@xavierchataign1 · X

RT @silvano_trotta: L'étude : https://t.co/Tkwi0sHhnf

Jul 3, 2025 · 15 shares · 75 followers View post →
CarreraS
@CarrerasSs1 · X

RT @silvano_trotta: L'étude : https://t.co/Tkwi0sHhnf

Jul 3, 2025 · 15 shares · 1 followers View post →
Daniel Caty
@DanielCaty1 · X

RT @silvano_trotta: L'étude : https://t.co/Tkwi0sHhnf

Jul 2, 2025 · 15 shares · 138 followers View post →
Claudie Reinhardt
@claudiereineart · X

RT @silvano_trotta: L'étude : https://t.co/Tkwi0sHhnf

Jul 2, 2025 · 15 shares · 4,627 followers View post →
Réinfo Québec
@reinfoquebec · X

RT @silvano_trotta: L'étude : https://t.co/Tkwi0sHhnf

Jul 2, 2025 · 15 shares · 13,131 followers View post →
Acua2701
@acua2701 · X

RT @silvano_trotta: L'étude : https://t.co/Tkwi0sHhnf

Jul 2, 2025 · 15 shares · 161 followers View post →
Alain Sillard
@Alainalbigone · X

RT @silvano_trotta: L'étude : https://t.co/Tkwi0sHhnf

Jul 2, 2025 · 15 shares · 117 followers View post →
PATRICK MEULEY
@PatrickMeuley · X

RT @silvano_trotta: L'étude : https://t.co/Tkwi0sHhnf

Jul 2, 2025 · 15 shares · 374 followers View post →
Natalia Nausica
@NataliaNausica · X

RT @silvano_trotta: L'étude : https://t.co/Tkwi0sHhnf

Jul 2, 2025 · 15 shares · 4,937 followers View post →
Agathethebus
@agathethebus · X

RT @silvano_trotta: L'étude : https://t.co/Tkwi0sHhnf

Jul 2, 2025 · 15 shares · 810 followers View post →
SILVANO TROTTA OFFICIEL
@silvano_trotta · X

L'étude : https://t.co/Tkwi0sHhnf

Jul 2, 2025 · 60 likes · 15 shares · 259,020 followers View post →
Dr. Carl Hindy
@DrCarlHindy · X

Antidepressant use is associated with faster cognitive decline: “Antidepressant use and cognitive decline in patients with dementia: a national cohort study” — BMC Medicine (Full Text) https://t.co/yEu5zppxl0

Jun 24, 2025 · 33,188 followers View post →
Salva Moreno
@shall_ontty · X

RT @psiquicritic: El uso de antidepresivos en personas con demencia se asocia con un deterioro cognitivo más rápido, fracturas y mortalidad…

Jun 14, 2025 · 41 shares · 2,106 followers View post →
Askgerbil Now
@Askgerbil · X

"a beneficial impact of SSRIs [anti-depressants] on neurogenesis and pathologic biomarkers, including amyloid burden and tau deposits, has been reported" https://t.co/0lLKLpvryD Medication for treating depression MAY possibly delay progress of dementia? Less Tau alleviates both?

Jun 11, 2025 · 4,230 followers View post →
Kendra
@KNor00 · X

@NeuroscienceNew Interesting…. https://t.co/JDSGfFeRuU

Jun 1, 2025 · 219 followers View post →
D
@Industryideator · X

@drfreshwater @NeuroscienceNew https://t.co/g56ZhpiTtE https://t.co/nNlEO4gsKB

Jun 1, 2025 · 1 like · 346 followers View post →
Nutrition1974
@Nutrition1974 · X

@NeuroscienceNew Don’t think that study is very reliable research considering the acknowledgements from the authors includes all the top pharmaceutical companies (see attached screenshot). A recent cohort study shows SSRI use was associated to faster cognitive decline

May 31, 2025 · 308 followers View post →
Yvonne
@YBartolovic · X

RT @SaeedDoroudiani: current antidepressant use was associated with faster cognitive decline higher dispensed doses of SSRIs were associat…

May 23, 2025 · 11 shares · 1,595 followers View post →
Informed Consent
@Ireland2020 · X

RT @SaeedDoroudiani: current antidepressant use was associated with faster cognitive decline higher dispensed doses of SSRIs were associat…

May 23, 2025 · 11 shares · 15,273 followers View post →
Fibroid New Research
@FibroidNetwork · X

RT @SaeedDoroudiani: current antidepressant use was associated with faster cognitive decline higher dispensed doses of SSRIs were associat…

May 23, 2025 · 11 shares · 3,244 followers View post →
recovery&renewal
@recover2renew · X

RT @SaeedDoroudiani: current antidepressant use was associated with faster cognitive decline higher dispensed doses of SSRIs were associat…

May 23, 2025 · 11 shares · 4,120 followers View post →
Kindly #deprescribe -- taper psychiatric drugs
@Altostrata · X

RT @SaeedDoroudiani: current antidepressant use was associated with faster cognitive decline higher dispensed doses of SSRIs were associat…

May 22, 2025 · 11 shares · 6,468 followers View post →
Alyne Duthie
@DuthieAlyne · X

RT @SaeedDoroudiani: current antidepressant use was associated with faster cognitive decline higher dispensed doses of SSRIs were associat…

May 22, 2025 · 11 shares · 1,876 followers View post →
Sharon Thornton
@_SharonThornton · X

RT @SaeedDoroudiani: current antidepressant use was associated with faster cognitive decline higher dispensed doses of SSRIs were associat…

May 22, 2025 · 11 shares · 895 followers View post →
dawn
@GoForDawn · X

RT @SaeedDoroudiani: current antidepressant use was associated with faster cognitive decline higher dispensed doses of SSRIs were associat…

May 22, 2025 · 11 shares · 2,119 followers View post →
Fiona French, freedom is bliss
@benzosarebad · X

RT @SaeedDoroudiani: current antidepressant use was associated with faster cognitive decline higher dispensed doses of SSRIs were associat…

May 22, 2025 · 11 shares · 6,766 followers View post →
Bert
@HenryRunamucker · X

RT @SaeedDoroudiani: current antidepressant use was associated with faster cognitive decline higher dispensed doses of SSRIs were associat…

May 22, 2025 · 11 shares · 2,125 followers View post →
Monica
@InsularEntropy · X

RT @SaeedDoroudiani: current antidepressant use was associated with faster cognitive decline higher dispensed doses of SSRIs were associat…

May 21, 2025 · 11 shares · 1,123 followers View post →
Saeed Doroudiani, MSc/PhD, PEng
@SaeedDoroudiani · X

current antidepressant use was associated with faster cognitive decline higher dispensed doses of SSRIs were associated with higher risk for severe dementia, fractures, and all-cause mortality #drugs #psychiatry #depression #dementia #brain #cognitive https://t.co/UycDWFbNiz

May 21, 2025 · 22 likes · 11 shares · 925 followers View post →
Isao Uno(宇野勲)/リハ栄養指導士/栄養嚥下理学療法
@isao_reha_nutri · X

認知症患者さんでは、抗うつ薬使用者は、非使用者と比較して、追跡期間中の認知機能の低下速度が速く、SSRIの用量が多いほど認知機能低下が加速し、重度認知症、全死亡率、骨折のリスクを高めるそうです。 https://t.co/xK5pCyhRWb

Apr 23, 2025 · 3 likes · 1,837 followers View post →
Tammy
@ThankfulTammy1 · X

RT @ChrisPalmerMD: @Christineschle7 This recent study found that they are "associated with" faster cognitive decline and all-cause mortalit…

Apr 8, 2025 · 1 share · 35 followers View post →
Reinis Lazda
@reinislazda.toot.lv.ap.brid.gy · Bluesky

Radās aizdomas, ka antidepresantu lietošana pazemina kognitīvās spējas (IQ) - un te nu ir nopietns longitudināls pētījums, kas to secina. Tas īpaši attiecas uz cilvēkiem, kuriem jau tā ir paaugstināts demences risks. https://bmcmedicine.biomedcentral.com/articles/10.1186/s12916-025-03851-3

Apr 8, 2025 · 1 like · 2 shares View post →
Reinis Lazda
@ReinisLazda · X

Something that I have been suspecting - antidepressant use can decrease cognitive abilities and speed up cognitive decline, especially in persons with higher baseline risks. https://t.co/TfcBR3IVBB

Apr 8, 2025 · 1 like · 1,892 followers View post →
Monica
@InsularEntropy · X

RT @SaeedDoroudiani: current antidepressant use was associated with faster cognitive decline; furthermore, higher dispensed doses of SSRIs…

Apr 4, 2025 · 1 share · 1,123 followers View post →
Saeed Doroudiani, MSc/PhD, PEng
@SaeedDoroudiani · X

current antidepressant use was associated with faster cognitive decline; furthermore, higher dispensed doses of SSRIs were associated with higher risk for severe dementia, fractures, and all-cause mortality #psychiatry #drugs #dementia #SSRI #depression https://t.co/UycDWFbNiz

Apr 4, 2025 · 5 likes · 1 share · 925 followers View post →
68-Tele
@68Tele_ · X

RT @StevePhillipsMD: Recent study: SSRI's (antidepressants) associated with dementia. Even worse: A dose response curve was seen. Higher…

Apr 4, 2025 · 7 shares · 115 followers View post →
Ramucho67
@ramucho67 · X

RT @StevePhillipsMD: Recent study: SSRI's (antidepressants) associated with dementia. Even worse: A dose response curve was seen. Higher…

Apr 3, 2025 · 7 shares · 1,887 followers View post →
Bocquet Annelise
@AnneliseBocquet · X

RT @StevePhillipsMD: Recent study: SSRI's (antidepressants) associated with dementia. Even worse: A dose response curve was seen. Higher…

Apr 3, 2025 · 7 shares · 29,136 followers View post →
CLAUDINE GAUTIER
@vicmahec · X

RT @StevePhillipsMD: Recent study: SSRI's (antidepressants) associated with dementia. Even worse: A dose response curve was seen. Higher…

Apr 3, 2025 · 7 shares · 1,610 followers View post →
Pinsolle Typhaine
@PinsolleT · X

RT @StevePhillipsMD: Recent study: SSRI's (antidepressants) associated with dementia. Even worse: A dose response curve was seen. Higher…

Apr 3, 2025 · 7 shares · 52,714 followers View post →
Ragnar K
@jazzybry5 · X

RT @StevePhillipsMD: Recent study: SSRI's (antidepressants) associated with dementia. Even worse: A dose response curve was seen. Higher…

Apr 2, 2025 · 7 shares · 3,123 followers View post →
Javed Alam
@jalam1001 · X

Title: Antidepressant use and cognitive decline in patients with dementia: a national cohort study DOI: https://t.co/NJmppqodLn --- Summary: This large national cohort study from Sweden investigated whether antidepressant use is associated with faster cognitive decline in https://t.co/qMJKVNQFjs https://t.co/tFyXTUeaz5

Apr 2, 2025 · 1,004 followers View post →
Karen Genest
@thegreenthumb12 · X

RT @StevePhillipsMD: Recent study: SSRI's (antidepressants) associated with dementia. Even worse: A dose response curve was seen. Higher…

Apr 2, 2025 · 7 shares · 1,010 followers View post →
Steven Phillips, MD
@StevePhillipsMD · X

Recent study: SSRI's (antidepressants) associated with dementia. Even worse: A dose response curve was seen. Higher doses associated with increased dementia, fractures, & death. Dose response curves are usually meaningful in such studies. https://t.co/kl0SG35JdM

Apr 2, 2025 · 15 likes · 7 shares · 82,892 followers View post →
Chris Palmer, MD
@ChrisPalmerMD · X

@Christineschle7 This recent study found that they are "associated with" faster cognitive decline and all-cause mortality. https://t.co/kncOOxr1sx

Mar 31, 2025 · 1 share · 134,111 followers View post →
Ssri fraud - you were cheated
@HuijausSsri · X

RT @joannamoncrieff: Study finds antidepressants associated with faster cognitive decline and increased risk of severe dementia, fractures…

Mar 30, 2025 · 87 shares · 52 followers View post →
Marian
@dophin11 · X

Current antidepressant use associated with faster cognitive decline; furthermore, higher dispensed doses of SSRIs were associated with higher risk for severe dementia, fractures, and all-cause mortality. https://t.co/eW7F0KkIYJ

Mar 29, 2025 · 1 like · 4,039 followers View post →
BMC
@BioMedCentral · X

A study published in @BMCMedicine finds that use of antidepressants, particularly selective serotonin reuptake inhibitors (citalopram, sertraline and escitalopram) and mirtazapine, is associated with faster cognitive decline in patients with dementia. https://t.co/I5lbqz2C0V

Mar 28, 2025 · 75,403 followers View post →
DiegoNeurociencias
@diegoneuro · X

RT @joannamoncrieff: This study is important because although effects were small, they were independent of depression and there was a dose…

Mar 25, 2025 · 30 shares · 498 followers View post →
Radoslaw Stupak
@RadoslawStupak · X

RT @joannamoncrieff: This study is important because although effects were small, they were independent of depression and there was a dose…

Mar 24, 2025 · 30 shares · 1,161 followers View post →
The Wellness Company
@twc_health · X

Find the study about the link between the increase in cognitive decline and antidepressants https://t.co/iA19IGDjQB

Mar 24, 2025 · 67,414 followers View post →
Mind Your Science!
@MindYourSci · X

RT @agingdoc1: Antidepressant use and cognitive decline in patients with dementia: a national cohort study https://t.co/ZDARkPZiWs https:/…

Mar 24, 2025 · 2 shares · 133 followers View post →
The Longevist
@Dr_coachbear · X

RT @agingdoc1: Antidepressant use and cognitive decline in patients with dementia: a national cohort study https://t.co/ZDARkPZiWs https:/…

Mar 24, 2025 · 2 shares · 515,327 followers View post →
Agingdoc
@agingdoc1 · X

Antidepressant use and cognitive decline in patients with dementia: a national cohort study https://t.co/ZDARkPZiWs https://t.co/Is0eVt7bAR

Mar 23, 2025 · 4 likes · 2 shares · 41,314 followers View post →
Esther K Haddad
@estherkhaddad · X

RT @joannamoncrieff: This study is important because although effects were small, they were independent of depression and there was a dose…

Mar 23, 2025 · 30 shares · 2,872 followers View post →
Dr Gemma Ahearne
@princessjack · X

RT @joannamoncrieff: This study is important because although effects were small, they were independent of depression and there was a dose…

Mar 23, 2025 · 30 shares · 9,563 followers View post →
Anna King
@AnnaKin06551830 · X

RT @joannamoncrieff: Study finds antidepressants associated with faster cognitive decline and increased risk of severe dementia, fractures…

Mar 23, 2025 · 87 shares · 3,095 followers View post →
David Fitzpatrick
@luanam465 · X

RT @joannamoncrieff: This study is important because although effects were small, they were independent of depression and there was a dose…

Mar 23, 2025 · 30 shares · 1,421 followers View post →
Nick Aspey
@NickAspey · X

RT @joannamoncrieff: This study is important because although effects were small, they were independent of depression and there was a dose…

Mar 23, 2025 · 30 shares · 835 followers View post →
Mike Casey
@casertron3000 · X

RT @joannamoncrieff: This study is important because although effects were small, they were independent of depression and there was a dose…

Mar 23, 2025 · 30 shares · 3,606 followers View post →
Mark Horowitz @markhoro.bsky.social
@markhoro · X

RT @joannamoncrieff: This study is important because although effects were small, they were independent of depression and there was a dose…

Mar 23, 2025 · 30 shares · 12,470 followers View post →
Rick Fearn
@RickFearn · X

RT @joannamoncrieff: This study is important because although effects were small, they were independent of depression and there was a dose…

Mar 23, 2025 · 30 shares · 346 followers View post →
David Hammerstein
@DaHammerstein · X

RT @joannamoncrieff: This study is important because although effects were small, they were independent of depression and there was a dose…

Mar 23, 2025 · 30 shares · 4,340 followers View post →
Mad In The UK
@MITUKteam · X

RT @joannamoncrieff: This study is important because although effects were small, they were independent of depression and there was a dose…

Mar 22, 2025 · 30 shares · 7,247 followers View post →
mur can
@CanUmr234 · X

RT @joannamoncrieff: This study is important because although effects were small, they were independent of depression and there was a dose…

Mar 22, 2025 · 30 shares · 75 followers View post →
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@PieAreSqwared · X

RT @joannamoncrieff: This study is important because although effects were small, they were independent of depression and there was a dose…

Mar 22, 2025 · 30 shares · 753 followers View post →
worldinian
@AilsaRayner · X

RT @joannamoncrieff: This study is important because although effects were small, they were independent of depression and there was a dose…

Mar 22, 2025 · 30 shares · 379 followers View post →
Eren
@Erena8008 · X

RT @joannamoncrieff: This study is important because although effects were small, they were independent of depression and there was a dose…

Mar 21, 2025 · 30 shares · 238 followers View post →
Marissa
@weigenijsje · X

RT @joannamoncrieff: This study is important because although effects were small, they were independent of depression and there was a dose…

Mar 21, 2025 · 30 shares · 376 followers View post →
Kyblueblood
@kyblueblood · X

RT @joannamoncrieff: This study is important because although effects were small, they were independent of depression and there was a dose…

Mar 21, 2025 · 30 shares · 33,898 followers View post →
Rob Purssey
@RPurssey · X

RT @joannamoncrieff: This study is important because although effects were small, they were independent of depression and there was a dose…

Mar 21, 2025 · 30 shares · 816 followers View post →
Fiz
@westcoastiscool · X

RT @joannamoncrieff: This study is important because although effects were small, they were independent of depression and there was a dose…

Mar 21, 2025 · 30 shares · 628 followers View post →
Kindly #deprescribe -- taper psychiatric drugs
@Altostrata · X

RT @joannamoncrieff: This study is important because although effects were small, they were independent of depression and there was a dose…

Mar 21, 2025 · 30 shares · 6,468 followers View post →
Sharon Thornton
@_SharonThornton · X

RT @joannamoncrieff: This study is important because although effects were small, they were independent of depression and there was a dose…

Mar 21, 2025 · 30 shares · 895 followers View post →
Dr Pardo
@Doctor_Pardo · X

RT @joannamoncrieff: This study is important because although effects were small, they were independent of depression and there was a dose…

Mar 21, 2025 · 30 shares · 4,165 followers View post →
Anna King
@AnnaKin06551830 · X

RT @joannamoncrieff: This study is important because although effects were small, they were independent of depression and there was a dose…

Mar 21, 2025 · 30 shares · 3,095 followers View post →
Informed Consent
@Ireland2020 · X

RT @joannamoncrieff: This study is important because although effects were small, they were independent of depression and there was a dose…

Mar 21, 2025 · 30 shares · 15,273 followers View post →
io
@kilnerevonnet · X

RT @joannamoncrieff: This study is important because although effects were small, they were independent of depression and there was a dose…

Mar 21, 2025 · 30 shares · 692 followers View post →
Aine
@amobeirne · X

RT @joannamoncrieff: This study is important because although effects were small, they were independent of depression and there was a dose…

Mar 21, 2025 · 30 shares · 3,041 followers View post →
recovery&renewal
@recover2renew · X

RT @joannamoncrieff: This study is important because although effects were small, they were independent of depression and there was a dose…

Mar 21, 2025 · 30 shares · 4,120 followers View post →
Alison Barrett
@DrAlisonBarrett · X

RT @joannamoncrieff: This study is important because although effects were small, they were independent of depression and there was a dose…

Mar 21, 2025 · 30 shares · 1,786 followers View post →
Dr Joanna Moncrieff
@joannamoncrieff · X

This study is important because although effects were small, they were independent of depression and there was a dose effect. It showed increased risk of cognitive decline, death and fractures was associated with antidepressant use in people with dementia https://t.co/7fwpU6P9mC https://t.co/XfvNqRzb9d

Mar 21, 2025 · 84 likes · 30 shares · 27,506 followers View post →
William aka Experiment 44
@idrinklife4444 · X

https://t.co/gfuV0QwPf2

Mar 17, 2025 · 901 followers View post →
SWA
@swalexander.bsky.social · Bluesky

Antidepressant use and cognitive decline in patients with dementia: a national cohort study bmcmedicine.biomedcentral.com/articles/10....

Mar 12, 2025 View post →
Salva Moreno
@shall_ontty · X

RT @psiquicritic: El uso de antidepresivos en personas con demencia se asocia con un deterioro cognitivo más rápido, fracturas y mortalidad…

Mar 12, 2025 · 41 shares · 2,106 followers View post →
帰ってきた売虎満(略:カエトラ)
@XMha7Jp228Gczio · X

RT @kinoshitayakuhi: 抗鬱剤SSRIの服用で認知症に https://t.co/xpHE07rUNI 論文:認知症患者における抗うつ薬の使用と認知機能低下、全国コホート研究 執筆者:スウェーデンのカロリンスカ研究所 掲載誌:BMC medicine 公開日…

Mar 7, 2025 · 35 shares · 494 followers View post →
P
@psychopharmacol · X

cohort study: Antidepressant use was associated with faster cognitive decline (β= −0.30; −0.39 to −0.21 points/year), in particular sertraline (−0.25), citalopram (−0.41), escitalopram (−0.76), and mirtazapine (−0.19) vs. non-use https://t.co/606g1GKu78 https://t.co/gZ00KP5hDl

Mar 7, 2025 · 3 likes · 577 followers View post →
ターコイズボイス
@NvgLnd · X

RT @kinoshitayakuhi: 抗鬱剤SSRIの服用で認知症に https://t.co/xpHE07rUNI 論文:認知症患者における抗うつ薬の使用と認知機能低下、全国コホート研究 執筆者:スウェーデンのカロリンスカ研究所 掲載誌:BMC medicine 公開日…

Mar 7, 2025 · 35 shares · 822 followers View post →
path
@path_psy_ · X

RT @tsuyomiyakawa: アルツハイマー病患者1万8千人以上について調べ、抗うつ薬の使用が認知機能の低下に相関していること、処方量が多いほど認知症のリスクが高いことを示した大規模研究。歯状回の脱成熟が患者でも見られ、抗うつ薬投与で見られることを考えると合理的な結果。…

Mar 3, 2025 · 7 shares · 771 followers View post →
Shashi Agarwal, MD
@usacardiologist · X

SSRIs & dementia acceleration (2 of 3) #dementia The study also revealed that higher dispensed doses of SSRIs were associated with higher risk for severe dementia, fractures, and all-cause mortality. (BMC Med 23, 82 (2025). https://t.co/KbP7p92com)

Mar 2, 2025 · 18 followers View post →
aleix cardona jordan #antifa
@aleixcj · X

RT @JuanGrvas: ¿Demencia? ¡No tome guarrerías! (antidepresivos) Current antidepressant use associated with faster cognitive decline; furthe…

Mar 2, 2025 · 5 shares · 2,109 followers View post →
Alzheimer's Prevention
@AlzheimersPrev2 · X

Antidepressant use and cognitive decline in patients with dementia: a national cohort study. Antidepressants accelerated cognitive decline, while others had a milder effect. These findings highlight the need for more personalized treatment strategies. https://t.co/QMM300C1MT

Mar 1, 2025 · 373 followers View post →
D
@Industryideator · X

@SterlingCooley @X Meanwhile standard of care “antidepressants” may well contribute to cognitive decline: “Antidepressant use and cognitive decline in patients with dementia: a national cohort study” https://t.co/nNlEO4gsKB

Feb 28, 2025 · 3 likes · 346 followers View post →
Springer Nature
@SpringerNature · X

One of our top rated articles according to @altmetric this past week was published OA in @BMCMedicine. You can read 'Antidepressant use and cognitive decline in patients with dementia: a national cohort study' here: https://t.co/SIkKPQwVkm

Feb 28, 2025 · 82,591 followers View post →
Springer Nature
@springernature.com · Bluesky

One of our top rated articles according to @altmetric.com this past week was published OA in @biomedcentral.bsky.social. You can read 'Antidepressant use and cognitive decline in patients with dementia: a national cohort study' here

Feb 28, 2025 · 4 likes · 1 share View post →
GreenDoc Gwen
@ecogwendoc · X

RT @PharmacyOnline8:

Feb 28, 2025 · 5 shares · 23 followers View post →
Digital Health and Patient Safety Platform
@DHPSP · X

RT @PharmacyOnline8:

Feb 28, 2025 · 5 shares · 6,739 followers View post →
International Natural Product Sciences Taskforce
@_INPST · X

RT @PharmacyOnline8:

Feb 28, 2025 · 5 shares · 10,262 followers View post →
Science Communication
@ScienceCommuni2 · X

RT @PharmacyOnline8:

Feb 28, 2025 · 5 shares · 2,870 followers View post →
Atanas G. Atanasov
@_atanas_ · X

RT @PharmacyOnline8:

Feb 28, 2025 · 5 shares · 123,532 followers View post →
Online Pharmacy
@PharmacyOnline8 · X

Feb 27, 2025 · 10 likes · 5 shares · 6,260 followers View post →
Antonio Palomar
@GarcPalomar · X

Algunos antidepresivos de la familia del Prozac (ISRS) podrían acelerar el deterioro cognitivo n personas con demencia. Instituto Karolinska-Suecia Minjia Mo et al. “Antidepressant use and cognitive decline in patients with dementia: a national cohort study”. BMC Medicine (2025)

Feb 27, 2025 · 4,185 followers View post →
Saeed Doroudiani, MSc/PhD, PEng
@SaeedDoroudiani · X

"In this cohort study, current antidepressant use was associated with faster cognitive decline ..." BUT, providers (GP, #Neurology doc et al.) usually say #antidepressant are safe & harmless #Healthcare #toxicity #dementia #MentalHealth #cognitive https://t.co/UycDWFbNiz

Feb 26, 2025 · 925 followers View post →
いっちー@バーチャル精神科医
@ichiipsy · X

Mo, M., Abzhandadze, T., Hoang, M.T. et al. Antidepressant use and cognitive decline in patients with dementia: a national cohort study. BMC Med 23, 82 (2025). https://t.co/JmZS5EUmsv

Feb 26, 2025 · 4 likes · 78,690 followers View post →
Marko Louevuo
@markolouevuo.bsky.social · Bluesky

Antidepressant use and cognitive decline in patients with dementia: a national cohort study bmcmedicine.biomedcentral.com/articles/10....

Feb 25, 2025 · 2 likes View post →
Marko Louevuo
@MarkoLouevuo · X

Antidepressant use and cognitive decline in patients with dementia: a national cohort study https://t.co/H7e9T1OSZc

Feb 25, 2025 · 479 followers View post →
Lucia Ruggiero EALR
@luciaruggiero · X

RT @GlobalPHObserv: Antidepressant use and cognitive decline in patients with dementia: a national cohort study https://t.co/bGBf0rpLIk

Feb 25, 2025 · 3 shares · 1,028 followers View post →
Culture of Health Eq
@CofHEQ · X

RT @GlobalPHObserv: Antidepressant use and cognitive decline in patients with dementia: a national cohort study https://t.co/bGBf0rpLIk

Feb 25, 2025 · 3 shares · 1,095 followers View post →
Equity & Health
@equitylist · X

RT @GlobalPHObserv: Antidepressant use and cognitive decline in patients with dementia: a national cohort study https://t.co/bGBf0rpLIk

Feb 25, 2025 · 3 shares · 28,907 followers View post →
choshib.bsky.social
@choshib.bsky.social · Bluesky

‼️Antidepressant use and cognitive decline in patients with dementia: a national cohort study bmcmedicine.biomedcentral.com/articles/10....

Feb 25, 2025 View post →
_entia
@tUBQsWkmTQlf40S · X

Antidepressant use and cognitive decline in patients with dementia: a national cohort study https://t.co/YNRwOZXsk8

Feb 25, 2025 · 1 like · 115 followers View post →
Global Health Observ
@GlobalPHObserv · X

Antidepressant use and cognitive decline in patients with dementia: a national cohort study https://t.co/bGBf0rpLIk

Feb 25, 2025 · 5 likes · 3 shares · 6,543 followers View post →