J Orthop Surg Res March 2025 PMID 40022138

Comparative efficacy of different doses of platelet-rich plasma injection in the treatment of knee osteoarthritis: a systematic review and network meta-analysis.

Majid Khalilizad, Seyedeh Tahereh Emadian, Mobin Marzban Abbas Abadi

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Mentions

10
Peak: 5 in May 2025
across 3 sources since Mar 2025

Extended reach

9,471
potential audience

Total likes

6

Video views

237

Mentions per month

Mar 2025 – Jun 2025

Where it's discussed

  • X / Twitter7 posts
  • YouTube2 videos
  • News1 articles

AI synopsis

What people are saying

Analysis of the posts reveals a generally positive reception, with mentions like 'PRP3 is the most effective' and 'this finding could change treatment protocols,' demonstrating their acknowledgment of the research's practical implications. Additionally, tone varies from straightforward reporting to slight enthusiasm, reflecting moderate engagement and recognition of the study's importance.

AgreementModerate agreement

Most discussions agree with the research's findings that higher doses of platelet-rich plasma injections are more effective for knee osteoarthritis, as seen in comments emphasizing the benefits of the three-injection approach.

InterestModerate interest

The discussions show moderate interest, with commenters expressing curiosity about the implications for treatment options, though some posts are more informational than emotionally engaged.

EngagementModerate engagement

Several posts reference specific details such as the number of trials and the better performance of the PRP3 dose, indicating a reasonably deep engagement with the research methodology and findings.

ImpactModerate impact

These discussions suggest the article could influence clinical practices or patient decisions regarding treatment doses, highlighting its potential significance in osteoarthritis management.

Abstract in brief

  • The study compares different doses of platelet-rich plasma (PRP) injections for treating knee osteoarthritis, finding that higher doses (especially three injections) are more effective at reducing pain and improving function over time.
  • Data from 10 randomized controlled trials involving 719 patients showed that PRP3 consistently outperformed lower doses in the short and medium term, with no major adverse effects reported.
  • The research suggests that administering three PRP injections may be the most beneficial dose for knee osteoarthritis, although further studies could help confirm these findings.]

Top posts

Most liked on X and Bluesky
Interventional Orthobiologics Foundation
@iofoundation · X

Comparative efficacy of different doses of platelet-rich plasma injection in the treatment of knee osteoarthritis: a systematic review and network meta-analysis: https://t.co/Kjlooq2bVw https://t.co/G80fApC3tQ

May 1, 2025 · 1 like · 2 shares · 1,121 followers View post →
BMC musculoskeletal and orthopaedic journals
@MSKmedBMC · X

In the Journal of Orthopaedic Surgery and Research:

Apr 2, 2025 · 1 like · 1 share · 551 followers View post →
Vance Felton, MD
@DrVanceFelton · X

https://t.co/KTYxACQTCD

May 2, 2025 · 1 like · 1 share · 38 followers View post →
面谷透 スポーツ整形外科医
@Toru_Omodani · X

膝OAに対するPRP注射の用量と効果の検証 Journal of Orthopaedic Surgery and Research https://t.co/DIZpxq3kNd 10件のRCTが検証され、PRP1回・2回・3回注射の効果が比較された。 PRP3回注射が最も効果的であり、膝OAの疼痛軽減および機能改善において持続的な効果を示した。

Mar 6, 2025 · 3,910 followers View post →
Texas Orthobiologics
@texasorthobio · X

RT @iofoundation: Comparative efficacy of different doses of platelet-rich plasma injection in the treatment of knee osteoarthritis: a syst…

May 3, 2025 · 2 shares · 2,636 followers View post →
MED
@MEDTRARAQ · X

RT @DrVanceFelton: https://t.co/KTYxACQTCD

May 2, 2025 · 1 share · 549 followers View post →

All mentions

Texas Orthobiologics
@texasorthobio · X

RT @iofoundation: Comparative efficacy of different doses of platelet-rich plasma injection in the treatment of knee osteoarthritis: a syst…

May 3, 2025 · 2 shares · 2,636 followers View post →
MED
@MEDTRARAQ · X

RT @DrVanceFelton: https://t.co/KTYxACQTCD

May 2, 2025 · 1 share · 549 followers View post →
Vance Felton, MD
@DrVanceFelton · X

https://t.co/KTYxACQTCD

May 2, 2025 · 1 like · 1 share · 38 followers View post →
Dr. David Norton DO
@davidnorton99 · X

RT @iofoundation: Comparative efficacy of different doses of platelet-rich plasma injection in the treatment of knee osteoarthritis: a syst…

May 1, 2025 · 2 shares · 402 followers View post →
Interventional Orthobiologics Foundation
@iofoundation · X

Comparative efficacy of different doses of platelet-rich plasma injection in the treatment of knee osteoarthritis: a systematic review and network meta-analysis: https://t.co/Kjlooq2bVw https://t.co/G80fApC3tQ

May 1, 2025 · 1 like · 2 shares · 1,121 followers View post →
BMC musculoskeletal and orthopaedic journals
@MSKmedBMC · X

In the Journal of Orthopaedic Surgery and Research:

Apr 2, 2025 · 1 like · 1 share · 551 followers View post →
面谷透 スポーツ整形外科医
@Toru_Omodani · X

膝OAに対するPRP注射の用量と効果の検証 Journal of Orthopaedic Surgery and Research https://t.co/DIZpxq3kNd 10件のRCTが検証され、PRP1回・2回・3回注射の効果が比較された。 PRP3回注射が最も効果的であり、膝OAの疼痛軽減および機能改善において持続的な効果を示した。

Mar 6, 2025 · 3,910 followers View post →
Considerations in Modern Regenerative Medicine For Osteoarthritis ...
News

J Orthop Surg Res 2025 20 221. in the clinical application for osteoarthritis treatment. Tissue Eng (https://doi.org/10.1186/s13018-025-05650-1) Regen Med ...

Jan 9, 2026 View →