Nat Microbiol April 2025 PMID 40033140

Dietary fibre counters the oncogenic potential of colibactin-producing Escherichia coli in colorectal cancer.

Bhupesh Kumar Thakur, Yann Malaise, Saurav Roy Choudhury, Anna Neustaeter, Williams Turpin, Catherine Streutker, Julia Copeland, Erin O Y Wong, William W Navarre, David S Guttman, Christian Jobin, Kenneth Croitoru, Alberto Martin

Mentions

184
Peak: 7 in Mar 2025
across 7 sources since Mar 2025

Extended reach

224,802
potential audience

Total likes

63

Video views

357

Mentions per month

Mar 2025 – Oct 2025

Where it's discussed

  • News160 articles
  • X / Twitter12 posts
  • Bluesky3 posts
  • Facebook3 posts
  • YouTube2 videos
  • Reddit2 posts
  • Blogs2 articles

AI synopsis

What people are saying

The overall discussions reflect a strong consensus on the importance of dietary fiber in countering bacterial effects linked to colon cancer, with posts describing the findings as 'game-changing' and referencing practical implications like 'eat your veggies.' The tone is enthusiastic and emphasizes the significance of microbiology research, demonstrating deep engagement and recognition of the study's potential for broad impact.

AgreementStrong agreement

Most discussions strongly support the findings, emphasizing the protective role of dietary fiber against bacterial-induced colorectal cancer.

InterestHigh interest

Participants show high interest, mentioning the connection between diet, microbiome, and cancer, and referencing the significance of the research.

EngagementModerate engagement

Posts engage with the content by discussing broader implications, potential dietary recommendations, and even mentioning related topics like microbiology and public health.

ImpactHigh impact

The discourse suggests that the publication is perceived as highly impactful, with some posts highlighting its potential to influence future research and dietary guidelines.

Abstract in brief

  • Dietary fiber, specifically soluble fiber like inulin, can reduce the cancer-promoting effects of certain bacteria (like pks E. coli) in the colon by decreasing inflammation and DNA damage.
  • Mice fed a low-carbohydrate, high-fat, and high-sugar diet showed increased colon polyps and inflammation, promoting bacterial growth and cancer risk; this was reversed by dietary fiber or PPAR agonists.
  • Host genetics, such as mismatch repair deficiency, make the colon more susceptible to bacterial-induced tumor formation, especially under pro-inflammatory conditions, highlighting interactions between diet, genetics, and microbiome in colorectal cancer risk.]

Top posts

Most liked on X and Bluesky
Nature Reviews Microbiology
@natrevmicro.nature.com · Bluesky

#midweekmicro

Mar 5, 2025 · 20 likes · 9 shares View post →
Huiluo Cao 曹慧荦
@hlcao · X

Dietary fibre counters the oncogenic potential of colibactin-producing Escherichia coli in colorectal cancer | Nature Microbiology https://t.co/LTRiGYjxYn

Mar 5, 2025 · 13 likes · 2 shares · 2,828 followers View post →
Huiluo Cao 曹慧荦
@hlcao · X

Dietary fibre counters the oncogenic potential of colibactin-producing Escherichia coli in colorectal cancer | Nature Microbiology https://t.co/LTRiGYjxYn

May 14, 2025 · 12 likes · 3 shares · 2,828 followers View post →
Agingdoc
@agingdoc1 · X

Dietary fibre counters the oncogenic potential of colibactin-producing Escherichia coli in colorectal cancer https://t.co/9PNzm7uubG

Mar 16, 2025 · 8 likes · 1 share · 41,394 followers View post →
Oliver Theunissen
@revulo.bsky.social · Bluesky

Colibactin may be the cause of colon cancer rise in under-50s, but help is just around the corner: »Dietary fibre counters the oncogenic potential of colibactin-producing Escherichia coli in colorectal cancer.« www.nature.com/articles/s41... #Eatyourveggies

Apr 23, 2025 · 2 likes View post →
Evgenii Protasov
@evgenii-protasov.bsky.social · Bluesky

Dietary fibre counters the oncogenic potential of colibactin-producing Escherichia coli in colorectal cancer #microbiology #colorectalcancer @natmicrobiol.nature.com www.nature.com/articles/s41...

Jun 24, 2025 · 1 like · 2 shares View post →

All mentions

Altamiro Bottino
@BottinoAltamiro · X

Dietary fibre counters the oncogenic potential of colibactin-producing Escherichia coli in colorectal cancer https://t.co/WOUGlawBoi https://t.co/YTtwuyD1HT

Oct 1, 2025 · 93 followers View post →
Evgenii Protasov
@protasov_evgeni · X

Dietary fibre counters the oncogenic potential of colibactin-producing Escherichia coli in colorectal cancer #microbiology #colorectalcancer @NatureMicrobiol https://t.co/91ofGI9BFu

Jun 25, 2025 · 511 followers View post →
Evgenii Protasov
@evgenii-protasov.bsky.social · Bluesky

Dietary fibre counters the oncogenic potential of colibactin-producing Escherichia coli in colorectal cancer #microbiology #colorectalcancer @natmicrobiol.nature.com www.nature.com/articles/s41...

Jun 24, 2025 · 1 like · 2 shares View post →
pepper_min
@peppermin5 · X

RT @hlcao: Dietary fibre counters the oncogenic potential of colibactin-producing Escherichia coli in colorectal cancer | Nature Microbiolo…

May 15, 2025 · 3 shares · 842 followers View post →
priya joseph
@ayirpelle · X

RT @hlcao: Dietary fibre counters the oncogenic potential of colibactin-producing Escherichia coli in colorectal cancer | Nature Microbiolo…

May 15, 2025 · 3 shares · 4,902 followers View post →
Huiluo Cao 曹慧荦
@hlcao · X

Dietary fibre counters the oncogenic potential of colibactin-producing Escherichia coli in colorectal cancer | Nature Microbiology https://t.co/LTRiGYjxYn

May 14, 2025 · 12 likes · 3 shares · 2,828 followers View post →
Peeref
@Peeref1 · X

May 13, 2025 · 164 followers View post →
Oliver Theunissen
@revulo.bsky.social · Bluesky

Colibactin may be the cause of colon cancer rise in under-50s, but help is just around the corner: »Dietary fibre counters the oncogenic potential of colibactin-producing Escherichia coli in colorectal cancer.« www.nature.com/articles/s41... #Eatyourveggies

Apr 23, 2025 · 2 likes View post →
David Weinkove
@dweinkove · X

RT @agingdoc1: Dietary fibre counters the oncogenic potential of colibactin-producing Escherichia coli in colorectal cancer https://t.co/9…

Mar 16, 2025 · 1 share · 2,343 followers View post →
Agingdoc
@agingdoc1 · X

Dietary fibre counters the oncogenic potential of colibactin-producing Escherichia coli in colorectal cancer https://t.co/9PNzm7uubG

Mar 16, 2025 · 8 likes · 1 share · 41,394 followers View post →
Fernanda Manieri, PhD
@freakfer · X

RT @hlcao: Dietary fibre counters the oncogenic potential of colibactin-producing Escherichia coli in colorectal cancer | Nature Microbiolo…

Mar 6, 2025 · 2 shares · 275 followers View post →
Tonya Ward
@T_L_Ward · X

RT @hlcao: Dietary fibre counters the oncogenic potential of colibactin-producing Escherichia coli in colorectal cancer | Nature Microbiolo…

Mar 5, 2025 · 2 shares · 285 followers View post →
Huiluo Cao 曹慧荦
@hlcao · X

Dietary fibre counters the oncogenic potential of colibactin-producing Escherichia coli in colorectal cancer | Nature Microbiology https://t.co/LTRiGYjxYn

Mar 5, 2025 · 13 likes · 2 shares · 2,828 followers View post →
Nature Reviews Microbiology
@natrevmicro.nature.com · Bluesky

#midweekmicro

Mar 5, 2025 · 20 likes · 9 shares View post →
背包健客
@bbjk666 · X

参考文献: https://t.co/qY0OGj1EjN

Mar 4, 2025 · 167,925 followers View post →