PLoS One March 2025 PMID 40043017

Menopausal symptom burden as a predictor of mid- to late-life cognitive function and mild behavioral impairment symptoms: A CAN-PROTECT study.

Jasper F E Crockford, Dylan X Guan, Gillian Einstein, Clive Ballard, Byron Creese, Anne Corbett, Ellie Pickering, Adam Bloomfield, Pamela Roach, Eric E Smith, Zahinoor Ismail

Mentions

136
Peak: 4 in Mar 2025
across 5 sources since Mar 2024

Extended reach

39,409
potential audience

Total likes

7

Video views

435

Mentions per month

Mar 2024 – Aug 2025

Where it's discussed

  • News113 articles
  • X / Twitter11 posts
  • Blogs9 articles
  • YouTube2 videos
  • Bluesky1 posts

AI synopsis

What people are saying

Several discussions underline the importance of the research, with posts mentioning that menopausal symptoms like forgetfulness and hot flashes could signal susceptibility to dementia, employing a tone of concern and urgency. The use of phrases like 'warning sign' and 'new study' emphasizes the perceived importance and potential impact on health practices, demonstrating strong engagement and interest among participants.

AgreementStrong agreement

Most discussions acknowledge and support the study’s findings, emphasizing the link between menopausal symptoms and cognitive decline.

InterestHigh interest

The posts demonstrate high interest, highlighting serious concerns like the risk of future dementia and the potential for menopausal symptoms to serve as early indicators.

EngagementHigh engagement

Many comments reference specific symptoms such as hot flashes, sleep problems, and forgetfulness, indicating deep engagement with the research's implications.

ImpactHigh impact

The discussions reflect a recognition of the findings’ potential significance for health awareness and future preventive strategies, suggesting high impact.

Abstract in brief

  • The study examined the link between menopausal symptoms and cognitive/behavioral changes in 896 postmenopausal women.
  • Higher menopausal symptom burden was found to correlate with worse cognitive function and increased behavioral impairment scores.
  • Hormone therapy did not significantly affect cognitive scores but was associated with lower behavioral impairment scores.

Top posts

Most liked on X and Bluesky
CAN-PROTECT
@canprotectstudy · X

Mar 31, 2025 · 5 likes · 3 shares · 16 followers View post →
medRxiv
@medrxivpreprint · X

Menopausal symptom burden as a predictor of mid- to late-life cognitive function and mild behavioral impairment symptoms: A CAN-PROTECT study. https://t.co/xxAzgqFdn6 #medRxiv

Mar 15, 2024 · 17,467 followers View post →
UCalgaryMedicine
@UCalgaryMed · X

RT @canprotectstudy:

Apr 1, 2025 · 3 shares · 12,329 followers View post →
Gary Holden
@Info4Practice · X

New on https://t.co/8pxKdRDxAR | Menopausal symptom burden as a predictor of mid- to late-life cognitive function and mild behavioral impairment symptoms: A CAN-PROTECT study | https://t.co/BzT8C67a3P https://t.co/9aMe9YBUr7

Apr 20, 2025 · 4,721 followers View post →
Hotchkiss Brain Institute (HBI)
@HotchkissBrain · X

RT @canprotectstudy:

Mar 31, 2025 · 3 shares · 3,374 followers View post →
Better Mobility Lab
@MobilityBetter · X

RT @canprotectstudy:

Apr 2, 2025 · 3 shares · 530 followers View post →

All mentions

Women's Brain Health in Midlife and Menopause Impact

Most people think Alzheimers is a disease of old age. New research shows brain changes start decades earlier, especially in women, with hormonal shifts during menopause playing a key role. Early prevention strategies…

Entavida · Aug 5, 2025 288 views
Elea Rom
@Lbnromro · X

Más información Crockford, J. F. E., Guan, D. X., Einstein, G., et al., (2025). Menopausal symptom burden as a predictor of mid- to late-life cognitive function and mild behavioral impairment symptoms: A CAN-PROTECT study. PLoS ONE, 20(3), e0301165. https://t.co/qgnjb6sy0E

Jul 2, 2025 · 5 followers View post →
Elea Rom
@Lbnromro · X

Menopausia y Cerebro Lo que Necesitas Saber

Jul 2, 2025 · 5 followers View post →
Gary Holden
@Info4Practice · X

New on https://t.co/8pxKdRDxAR | Menopausal symptom burden as a predictor of mid- to late-life cognitive function and mild behavioral impairment symptoms: A CAN-PROTECT study | https://t.co/BzT8C67a3P https://t.co/9aMe9YBUr7

Apr 20, 2025 · 4,721 followers View post →
Better Mobility Lab
@MobilityBetter · X

RT @canprotectstudy:

Apr 2, 2025 · 3 shares · 530 followers View post →
UCalgaryMedicine
@UCalgaryMed · X

RT @canprotectstudy:

Apr 1, 2025 · 3 shares · 12,329 followers View post →
Hotchkiss Brain Institute (HBI)
@HotchkissBrain · X

RT @canprotectstudy:

Mar 31, 2025 · 3 shares · 3,374 followers View post →
CAN-PROTECT
@canprotectstudy · X

Mar 31, 2025 · 5 likes · 3 shares · 16 followers View post →
Canadian Longevity Association
@canlongevity · X

2/2 "These findings suggest that the experience of menopause may indicate susceptibility to cognitive and behavioural changes, both markers of dementia." https://t.co/JpQfA5IqYR

Mar 17, 2025 · 120 followers View post →
Bina Pattel
@BinaPattel · X

DIFFICULT #MENOPAUSE WARNING SIGN FOR FUTURE DEMENTIA – NEW STUDY https://t.co/ezXOjxB9Es HOT FLASHES NIGHT SWEATS SLEEP PROBLEMS CHILLS WEIGHT GAIN MOOD SYMPTOMS FORGETFULNESS MORE LIKELY TO DEVELOP EARLY SIGNS OF DEMENTIA LIKE DECREASED MENTAL FUNCTION https://t.co/1MOrSayyC4

Mar 9, 2025 · 36 followers View post →
SciencesNetwork
@SciencesNetwork · X

Menopausal symptom burden as a predictor of mid- to late-life cognitive function and mild behavioral impairment symptoms: A CAN-PROTECT study. https://t.co/vpOO5IScXc

Mar 15, 2024 · 345 followers View post →
medRxivpreprint
@medrxivpreprint.bsky.social · Bluesky

Menopausal symptom burden as a predictor of mid- to late-life cognitive function and mild behavioral impairment symptoms: A CAN-PROTECT study. https://www.medrxiv.org/content/10.1101/2024.03.13.24304247v1

Mar 15, 2024 · 1 share View post →
medRxiv
@medrxivpreprint · X

Menopausal symptom burden as a predictor of mid- to late-life cognitive function and mild behavioral impairment symptoms: A CAN-PROTECT study. https://t.co/xxAzgqFdn6 #medRxiv

Mar 15, 2024 · 17,467 followers View post →