March 2025 PMID 40103821

The relationship between amino acids and gastroesophageal reflux disease: evidence from a mendelian randomization analysis combined with a meta-analysis.

Jianjun Shen, Yongqing Guo, Rui Cao

Mentions

56
Peak: 9 in Nov 2025
across 5 sources since Mar 2025

Extended reach

35,766
potential audience

Total likes

16

Video views

911

Mentions per month

Mar 2025 – Nov 2025

Where it's discussed

  • TikTok49 posts
  • X / Twitter2 posts
  • YouTube2 videos
  • Facebook2 posts
  • Instagram1 posts

AI synopsis

What people are saying

The discussions highlight general curiosity about amino acids like glutamine and their effects on health, with phrases like '¿quién lo hace bien y quién lo hace mal?' showing practical concerns, while references to the research emphasize its relevance to dietary supplements and gastrointestinal issues. The tone combines mild skepticism and interest, reflecting a balanced but moderately engaged response to the article's findings.

AgreementNeither agree nor disagree

The posts do not entirely agree or disagree but acknowledge the research, indicating a neutral stance regarding its conclusions.

InterestModerate interest

There is moderate interest, as evidenced by a focus on relevant topics like amino acids and gastrointestinal health, though without deep technical engagement.

EngagementModerate engagement

Some posts show active participation by discussing dietary supplements and referencing the research, but overall, engagement remains moderate.

ImpactNeutral impact

The publication may influence certain discussions about personalized nutrition and health but does not appear to cause widespread or immediate change in practices.

Abstract in brief

  • The study explores the complex relationship between amino acids and gastroesophageal reflux disease (GERD), highlighting how some amino acids, like glutamate, can worsen the condition, while others may have protective effects, emphasizing the importance of personalized nutrition.
  • Using advanced genetic analysis methods such as Mendelian randomization and meta-analysis, the research aims to identify biological factors linked to GERD, providing insights that could lead to new treatment targets.
  • The findings specifically indicate that glutamate increases the risk of GERD, and the study employed rigorous validation and correction techniques to ensure the reliability and accuracy of these results.]

Top posts

Most liked on X and Bluesky
Frontiers - Immunology
@FrontImmunol · X

New Research: The relationship between amino acids and gastroesophageal reflux disease: evidence from a mendelian randomization analysis combined with a meta-analysis https://t.co/b8cuSsYDxD #FrontiersIn #Immunology

Mar 15, 2025 · 2 likes · 33,907 followers View post →
Nut.CarlaPaola
@NutCarlaPaola · X

T6 Cap 5 | Glutamina, ¿músculo o intestino? Otro suplemento muy de moda es la #GLUTAMINA, algunos la utilizan para la #masamuscular y otros la para mejorar alguna #enfermedadintestinal. ¿Quién lo hace bien y quién lo hace mal? Aquí te lo cuento. https://t.co/3iRM0VMPKt

Jun 3, 2025 · 429 followers View post →

All mentions

Nut.CarlaPaola
@NutCarlaPaola · X

T6 Cap 5 | Glutamina, ¿músculo o intestino? Otro suplemento muy de moda es la #GLUTAMINA, algunos la utilizan para la #masamuscular y otros la para mejorar alguna #enfermedadintestinal. ¿Quién lo hace bien y quién lo hace mal? Aquí te lo cuento. https://t.co/3iRM0VMPKt

Jun 3, 2025 · 429 followers View post →
Frontiers - Immunology
@FrontImmunol · X

New Research: The relationship between amino acids and gastroesophageal reflux disease: evidence from a mendelian randomization analysis combined with a meta-analysis https://t.co/b8cuSsYDxD #FrontiersIn #Immunology

Mar 15, 2025 · 2 likes · 33,907 followers View post →
Ali Ramadan (@holisticali) | TikTok
TikTok

https://doi.org/10.3389/fimmu.2025.1420132 https://doi.org/10.3390/nu15163583 https://doi.org/10.1136/gutjnl-2013-306393 https://doi.org/10.1007/978-3-030 ...

Dec 15, 2025 View →
I really had fun with this challenge but here's some info on crappi ...
TikTok

... 10.3389/fimmu.2025.1420132 https://doi.org/10.3390/nu15163583 https://doi.org/10.1136/gutjnl-2013-306393 https://doi.org/10.1007/978-3-030-12318-5_8 https ...

Dec 15, 2025 View →
What Is Causing Heartburn | TikTok
TikTok

https://doi.org/10.3389/fimmu.2025.1420132 https://doi.org/10.3390/nu15163583 https://doi.org/10.1136/gutjnl-2013-306393 https://doi.org/10.1007/978-3-030 ...

Dec 15, 2025 View →
Holistic Ali
Facebook

... 10.3389/frhs.2024.1448913 #PhoneHygiene #HealthTips #BathroomHabits #Wellness ... 10.3389/fimmu.2025.1420132 https://doi.org/10.3390/nu15163583 https://doi ...

Dec 15, 2025 View →
Holistic Ali
Facebook

... 10.3389/fimmu.2022.988481 https://doi.org/10.1161/circulationaha.109.192627 ... 2025.1420132 https://doi.org/10.3390/nu15163583 https://doi.org/10.1136 ...

Dec 15, 2025 View →
Your favorite formulas for brain, digestion, joint health, and more ...
TikTok

... 10.3389/fmicb.2021.685027/full https ... fimmu.2025.1420132 https://doi.org/10.3390/nu15163583 https://doi ...

Nov 28, 2025 View →
BLACK FRIDAY SALE IS ON NOW! COLON CLEANSE BACK ...
TikTok

... 10.3389/fnut.2025.1550880 https://doi.org/10.3390/foods14132315 ... fimmu.2025.1420132 https://doi.org/10.3390/nu15163583 https://doi ...

Nov 28, 2025 View →
What if 30–90 seconds of discomfort could make you feel amazing ...
TikTok

... 10.3389/fneur.2023.1169795 https://doi.org/10.1111/j.1468-2982.2007 ... fimmu.2025.1420132 https://doi.org/10.3390/nu15163583 https ...

Nov 23, 2025 View →
Ever wonder if you're drinking enough water throughout the day? Fin ...
TikTok

... 10.3389/fimmu.2025.1420132 https://doi.org/10.3390/nu15163583 https://doi.org/10.1136/gutjnl-2013-306393 https://doi.org/10.1007/978-3-030 ...

Nov 19, 2025 View →
What if there's a tropical fruit with surprising health benefits yo ...
TikTok

... 10.3389/fimmu.2025.1420132 https://doi.org/10.3390/nu15163583 https://doi.org/10.1136/gutjnl-2013-306393 https://doi.org/10.1007/978-3-030 ...

Nov 17, 2025 View →
Do you use your phone in the bathroom? You might want to ...
TikTok

... 10.3389/fimmu.2025.1420132 https://doi.org/10.3390/nu15163583 https://doi.org/10.1136/gutjnl-2013-306393 https://doi.org/10.1007/978-3-030 ...

Nov 16, 2025 View →
Ever wonder why some people suddenly develop blood clots in their ...
TikTok

... 10.3389/fneur.2023.1169795 https://doi.org/10.1111/j.1468-2982.2007 ... fimmu.2025.1420132 https://doi.org/10.3390/nu15163583 https ...

Nov 8, 2025 View →
Why do some people struggle with belly fat despite diet and exercis ...
TikTok

... 10.3389/fimmu.2025.1420132 https://doi.org/10.3390/nu15163583 https://doi.org/10.1136/gutjnl-2013-306393 https://doi.org/10.1007/978-3-030 ...

Nov 6, 2025 View →
Understanding Chronic Itching Causes and Solutions | TikTok
TikTok

... 10.3389/fimmu.2025.1420132 https://doi.org/10.3390/nu15163583 https://doi.org/10.1136/gutjnl-2013-306393 https://doi.org/10.1007/978-3-030 ...

Nov 1, 2025 View →
Which of these do you eat? Many might be surprised with coffee but ...
TikTok

... 10.3389/fnut.2021.716783”. original sound - Ali Ramadan ... fimmu.2025.1420132 https://doi.org/10.3390/nu15163583 https ...

Oct 30, 2025 View →
How to Manage Nighttime Hunger for Better Sleep | TikTok
TikTok

... 10.3389/fimmu.2025.1420132 https://doi.org/10.3390/nu15163583 https://doi.org/10.1136/gutjnl-2013-306393 https://doi.org/10.1007/978-3-030 ...

Oct 28, 2025 View →
Ali Ramadan | Your favorite formulas for brain, digestion, joint health ...
Instagram

https://doi.org/10.3389/fimmu.2025.1420132 https://doi.org/10.3390/nu15163583 https://doi.org/10.1136/gutjnl-2013-306393 https://doi.org ...

Oct 23, 2025 View →
STOP HEARTBURN IN ITS TRACKS! Acid reflux can ruin your night ...
TikTok

... 10.3389/fimmu.2025.1420132 https://doi.org/10.3390/nu15163583 https://doi.org/10.1136/gutjnl-2013-306393 https://doi.org/10.1007/978-3-030 ...

Oct 21, 2025 View →
Why does your body gag so easily sometimes? The answer has ...
TikTok

... 10.3389/fphar.2018.00521 https://doi.org/10.1016/j.foodchem ... fimmu.2025.1420132 https://doi.org/10.3390/nu15163583 https://doi.org ...

Jun 27, 2025 View →
Ever woken up unable to move? The science behind sleep paralysis ...
TikTok

... 10.3389/fnut.2025.1550880 https://doi.org/10.3390/foods14132315 ... fimmu.2025.1420132 https://doi.org/10.3390/nu15163583 https://doi ...

Feb 1, 2025 View →
Understanding Geographic Tongue: Causes and Facts | TikTok
TikTok

... 10.3389/fnut.2025.1550880 https://doi.org/10.3390/foods14132315 ... fimmu.2025.1420132 https://doi.org/10.3390/nu15163583 https://doi ...

Dec 4, 2024 View →
HICCUP ALERT! What triggers yours? #HiccupsHealth ...
TikTok

... 10.3389/fnut.2025.1550880 https://doi.org/10.3390/foods14132315 ... fimmu.2025.1420132 https://doi.org/10.3390/nu15163583 https://doi ...

Nov 23, 2024 View →
Gangrene may lead to loss of limbs and amputations. The medical ...
TikTok

... 10.3389/fimmu.2025.1420132 https://doi.org/10.3390/nu15163583 https://doi.org/10.1136/gutjnl-2013-306393 https://doi.org/10.1007/978-3-030 ...

Sep 22, 2024 View →
Bloating is very uncomfortable, there are some ways to help ...
TikTok

... 10.3389/fneur.2023.1169795 https://doi.org/10.1111/j.1468-2982.2007 ... fimmu.2025.1420132 https://doi.org/10.3390/nu15163583 https ...

Aug 25, 2023 View →
Many people have premature grey hair, some causes can be due to ...
TikTok

... 10.3389/fnut.2022.987674 https://doi.org/10.12775/jehs.2023.45 ... fimmu.2025.1420132 https://doi.org/10.3390/nu15163583 https://doi ...

Aug 18, 2023 View →
If anyone tells you coffee isn't good for you then drop them, you don ...
TikTok

... 10.3389/fnut.2025.1550880 https://doi.org/10.3390/foods14132315 ... fimmu.2025.1420132 https://doi.org/10.3390/nu15163583 https://doi ...

Aug 7, 2023 View →
Gastritis is uncomfortable and painful. It can be helpful to start eat ...
TikTok

... 10.3389/fneur.2023.1169795 https://doi.org/10.1111/j.1468-2982.2007 ... fimmu.2025.1420132 https://doi.org/10.3390/nu15163583 https ...

Aug 1, 2023 View →
Carrots are one of my favorite vegetable. Carrots with some Lemon ...
TikTok

... 10.3389/fneur.2023.1169795 https://doi.org/10.1111/j.1468-2982.2007 ... fimmu.2025.1420132 https://doi.org/10.3390/nu15163583 https ...

Jul 25, 2023 View →
Understanding High Blood Pressure: Symptoms, Causes, and ...
TikTok

... 10.3389/fnut.2025.1550880 https://doi.org/10.3390/foods14132315 ... fimmu.2025.1420132 https://doi.org/10.3390/nu15163583 https://doi ...

Jul 24, 2023 View →
I ate a whole dragonfruit the other day, it's really delicious but let ...
TikTok

... 10.3389/fnut.2025.1550880 https://doi.org/10.3390/foods14132315 ... fimmu.2025.1420132 https://doi.org/10.3390/nu15163583 https://doi ...

Jul 22, 2023 View →
Health Benefits of Blackberries: Why You Should Eat Them ...
TikTok

... 10.3389/fnut.2025.1550880 https://doi.org/10.3390/foods14132315 ... fimmu.2025.1420132 https://doi.org/10.3390/nu15163583 https://doi ...

Jul 21, 2023 View →
Some warning signs to keep in mind, when it comes to stroke think ...
TikTok

... 10.3389/fneur.2023.1169795 https://doi.org/10.1111/j.1468-2982.2007 ... fimmu.2025.1420132 https://doi.org/10.3390/nu15163583 https ...

Jul 17, 2023 View →
Applying Olive oil helps to moisturize the scalp, omega 3s, drinking ...
TikTok

... 10.3389/fnut.2022.987674 https://doi.org/10.12775/jehs.2023.45 ... fimmu.2025.1420132 https://doi.org/10.3390/nu15163583 https://doi ...

Jun 20, 2023 View →
Migraines are the worst! Sources: https://www.mayoclinic.org/di ...
TikTok

... 10.3389/fnut.2021.716783. original sound - Ali Ramadan. 48Likes. 0 ... 10.3389/fimmu.2025.1420132 https://doi.org/10.3390/nu15163583 https ...

Jun 16, 2023 View →
What You Need to Know About Athlete's Foot Risks | TikTok
TikTok

... 10.3389/fneur.2023.1169795 https://doi.org/10.1111/j.1468-2982.2007 ... fimmu.2025.1420132 https://doi.org/10.3390/nu15163583 https ...

Jun 13, 2023 View →
Constipation is a widespread digestive concern that affects people ...
TikTok

... 10.3389/fneur.2023.1169795 https://doi.org/10.1111/j.1468-2982.2007 ... fimmu.2025.1420132 https://doi.org/10.3390/nu15163583 https ...

May 17, 2023 View →
Deep vein thrombosis (DVT) is a condition where a blood clot forms ...
TikTok

... 10.3389/fnut.2025.1550880 https://doi.org/10.3390/foods14132315 ... fimmu.2025.1420132 https://doi.org/10.3390/nu15163583 https://doi ...

May 12, 2023 View →
I like green apples with peanut butter. How do you eat apples ...
TikTok

... 10.3389/fnut.2025.1550880 https://doi.org/10.3390/foods14132315 ... fimmu.2025.1420132 https://doi.org/10.3390/nu15163583 https://doi ...

May 10, 2023 View →
Do you like spicy food? Did you know eating spicy food contain ...
TikTok

... 10.3389/fnut.2025.1550880 https://doi.org/10.3390/foods14132315 ... fimmu.2025.1420132 https://doi.org/10.3390/nu15163583 https://doi ...

Apr 27, 2023 View →
‏Drinking water is important because it helps to keep our bodies ...
TikTok

... 10.3389/fnut.2025.1550880 https://doi.org/10.3390/foods14132315 ... fimmu.2025.1420132 https://doi.org/10.3390/nu15163583 https://doi ...

Apr 23, 2023 View →
‏To do the wind relieving pose (Pawanmuktasana), follow these ...
TikTok

... 10.3389/fnut.2025.1550880 https://doi.org/10.3390/foods14132315 ... fimmu.2025.1420132 https://doi.org/10.3390/nu15163583 https://doi ...

Apr 13, 2023 View →
‏Do you eat too much sugar? Added sugar is a real problem, sugar ...
TikTok

... 10.3389/fimmu.2025.1420132 https://doi.org/10.3390/nu15163583 https://doi.org/10.1136/gutjnl-2013-306393 https://doi.org/10.1007/978-3-030 ...

Mar 31, 2023 View →
‏Headaches are the worst! What type of headache do you have? And ...
TikTok

... 10.3389/fnut.2025.1550880 https://doi.org/10.3390/foods14132315 ... fimmu.2025.1420132 https://doi.org/10.3390/nu15163583 https://doi ...

Mar 23, 2023 View →
Yoga Frog Pose Benefits: Improve Flexibility and Circulation | TikTok
TikTok

... 10.3389/fimmu.2025.1420132 https://doi.org/10.3390/nu15163583 https://doi.org/10.1136/gutjnl-2013-306393 https://doi.org/10.1007/978-3-030 ...

Mar 9, 2023 View →
‏This works great!! | TikTok
TikTok

... 10.3389/fneur.2023.1169795 https://doi.org/10.1111/j.1468-2982.2007 ... fimmu.2025.1420132 https://doi.org/10.3390/nu15163583 https ...

Mar 2, 2023 View →
‏Butt massages are great for your body as your butt is the largest ...
TikTok

... 10.3389/fnut.2025.1550880 https://doi.org/10.3390/foods14132315 ... fimmu.2025.1420132 https://doi.org/10.3390/nu15163583 https://doi ...

Feb 27, 2023 View →
‏Weakened valves and walls in the veins cause varicose veins. This ...
TikTok

... 10.3389/fneur.2023.1169795 https://doi.org/10.1111/j.1468-2982.2007 ... fimmu.2025.1420132 https://doi.org/10.3390/nu15163583 https ...

Feb 16, 2023 View →
Kiwi for Better Sleep: How Kiwis Can Improve Your Sleep Quality ...
TikTok

... 10.3389/fneur.2023.1169795 https://doi.org/10.1111/j.1468-2982.2007 ... fimmu.2025.1420132 https://doi.org/10.3390/nu15163583 https ...

Feb 11, 2023 View →
‏This works great! Taking care of your feet is very relaxing and part o ...
TikTok

... 10.3389/fnut.2025.1550880 https://doi.org/10.3390/foods14132315 ... fimmu.2025.1420132 https://doi.org/10.3390/nu15163583 https://doi ...

Feb 10, 2023 View →
Effective Remedies for Nausea and Throwing Up | TikTok
TikTok

... 10.3389/fnut.2025.1550880 https://doi.org/10.3390/foods14132315 ... fimmu.2025.1420132 https://doi.org/10.3390/nu15163583 https://doi ...

Feb 8, 2023 View →
You'll absorb iron better when taken with vitamin C and b12 w/folate ...
TikTok

... 10.3389/fneur.2023.1169795 https://doi.org/10.1111/j.1468-2982.2007 ... fimmu.2025.1420132 https://doi.org/10.3390/nu15163583 https ...

Jul 15, 2022 View →
Do you eat avocado? source for avocado: https://pubmed.ncbi.n ...
TikTok

... 10.3389/fnut.2025.1550880 https://doi.org/10.3390/foods14132315 ... fimmu.2025.1420132 https://doi.org/10.3390/nu15163583 https://doi ...

Jul 5, 2022 View →