Non-caloric sweetener effects on brain appetite regulation in individuals across varying body weights #obesity @NatMetabolism https://t.co/IMB3plqePq
Non-caloric sweetener effects on brain appetite regulation in individuals across varying body weights.
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Mar 2025 – Aug 2025Where it's discussed
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AI synopsis
What people are saying
The comments reflect a strong curiosity and concern about how non-caloric sweeteners like sucralose may stimulate appetite through brain connectivity changes, evidenced by phrases such as 'increase in hypothalamic blood flow' and warnings like 'beware diet drinks.' The tone varies from scientific and analytical to cautious and skeptical, showing an engaged audience that recognizes the potential influence of these findings but also questions their broader implications.
The discussions generally acknowledge the findings but show mixed views on their implications, with some posts supporting the idea that artificial sweeteners influence appetite regulation, while others remain cautious or skeptical.
Most discussions express high interest, with users engaging actively in sharing the research's details, potential health impacts, and related debates.
Posts include detailed summaries of the study, references to specific brain mechanisms, and mention of broader health contexts, indicating a moderate level of analytical engagement.
While some posts suggest the research could influence dietary choices and public health policies, other discussions remain exploratory, so the perceived overall impact is moderate.
Abstract in brief
- Noncaloric sweeteners like sucralose can stimulate appetite by activating brain regions involved in hunger, even without providing calories.
- Consuming sucralose increases blood flow in the hypothalamus and alters brain connectivity related to motivation and sensory processing, but does not directly increase hunger ratings as sucrose does.
- While sucrose raises blood sugar and decreases hypothalamic blood flow, sucralose does not significantly affect glucose levels, indicating different mechanisms behind their influence on appetite and brain activity.
Top posts
Most liked on X and BlueskyNon-caloric sweetener effects on brain appetite regulation in individuals across varying body weights “Sucralose, compared to sucrose and water, results in increased functional connections between the hypothalamus and brain regions involved in motivation and somatosensory
Non-caloric sweetener effects on brain appetite regulation in individuals across varying body weights https://t.co/CArzfdaWZT
Non-caloric sweetener effects on brain appetite regulation in individuals across varying body weights https://t.co/CArzfdaWZT https://t.co/Gw0gmFOjsX
سوکرالوز یک شیرینکنندهی بدون کالری پرکاربرد، میتونه با تأثیر روی هیپوتالاموس حتی بدون افزایش قند خون باعث افزایش احساس گرسنگی بشه و تنظیم اشتها رو مختل کنه. مصرف شیرینکنندههای بدون کالری ممکنه برخلاف تصور، به افزایش اشتها و احتمالاً پرخوری منجر بشه. https://t.co/2kLMpRCVYq
Non-caloric sweetener effects on brain appetite regulation in individuals across varying body weights | Nature Metabolism https://t.co/MkIuWhFi2c
All mentions
Impact of Non-Caloric Sweeteners on Brain Appetite Regulation
Non-caloric sweeteners like sucralose can stimulate appetite by activating brain regions involved in hunger, even without providing calories. The study examines how sucralose affects blood flow in the hypothalamus and…
Impact of Zero Calorie Sweeteners on Hunger and Brain Activity
This video discusses how non-caloric sweeteners like sucralose can activate hunger-related brain regions. A March 2025 study shows sucralose increases hunger cravings by 17% compared to sugar, while Allulose acts as a…
Analyzing the Ingredients and Dietary Impact of a Protein Bar with Reeses Flavor
OneBar teamed with Reeses to create an 18g protein bar. This video explores its ingredients, taste, and the effects of non-caloric sweeteners like sucralose on hunger cravings. Also discussed is the importance of…
Choosing the Cleanest Protein Powder for Health and Safety
Which protein is the cleanest? Organic, non-GMO, and stevia-sweetened options avoid artificial additives and glyphosate residues, ensuring a safer, healthier supplement.
Impact of Sucralose on Brain Regulation of Appetite and Weight Control
This study reveals that consuming sucralose can activate brain regions related to hunger, creating a false sense of energy intake. The effects are more pronounced in individuals with obesity and women, potentially…
@esaagar : https://t.co/u4AYNoDmlm
【Co】人工甘味料で脳がバグる? 体型の異なる成人75人の脳をスキャン スクラロース摂取で、視床下部の血流が増加 主観的空腹感も増加 他の脳領域と機能的結合が変化 スクロールでは、血糖値が上昇し視床下部の血流が減少、満腹感が増加 特に肥満女性で悪影響が大きい https://t.co/YYnZsQ74el
【RCT】人工甘味料はダイエットに逆効果!? 75人にスクラロース飲料を飲んだ脳を調査 視床下部の血流が少し増えただけ 空腹感は、ただの水を飲んだ場合とほぼ同じ https://t.co/YYnZsQ6woN
Ref.: https://t.co/VtMNj9fEQs
若年成人では、スクラロース(ノンカロリー甘味料)はスクロースと比較して、血糖値は上昇させずに視床下部の血流を増加させ、視床下部と脳の「動機づけ」「感覚処理」の領域との結びつきを強化させたそうです。 https://t.co/xMoPUkpVPV
DYK? Sucralose may stimulate appetite by disrupting normal brain signals that regulate hunger. In a crossover trial, it increased hypothalamic blood flow & altered brain connectivity vs. sucrose or water.
RT @agingdoc1: Non-caloric sweetener effects on brain appetite regulation in individuals across varying body weights https://t.co/CArzfdaW…
RT @agingdoc1: Non-caloric sweetener effects on brain appetite regulation in individuals across varying body weights https://t.co/CArzfdaW…
RT @agingdoc1: Non-caloric sweetener effects on brain appetite regulation in individuals across varying body weights https://t.co/CArzfdaW…
RT @agingdoc1: Non-caloric sweetener effects on brain appetite regulation in individuals across varying body weights https://t.co/CArzfdaW…
RT @agingdoc1: Non-caloric sweetener effects on brain appetite regulation in individuals across varying body weights https://t.co/CArzfdaW…
Non-caloric sweetener effects on brain appetite regulation in individuals across varying body weights https://t.co/CArzfdaWZT
RT @AeroUprising19: Here is your interesting read for the day: Non-caloric sweeteners in “diet” drinks actually lead to increased appetite…
Here is your interesting read for the day: Non-caloric sweeteners in “diet” drinks actually lead to increased appetite https://t.co/IbpgHYjgvy
A paper using RRID:SCR_009550 was just published in Nature Metabolism see "Non-caloric sweetener effects on brain appetite regulation in individuals across varying body weights". Thank you for making your methods matter! #reproducibility #ReproducibleResearch
RT @keita_masui: 人工甘味料水は、砂糖水よりも、より空腹感をもたらすとの研究結果。本末転倒だ。。。 Chakravartti, S.P., Jann, K., Veit, R. et al. Non-caloric sweetener effects on br…
RT @keita_masui: 人工甘味料水は、砂糖水よりも、より空腹感をもたらすとの研究結果。本末転倒だ。。。 Chakravartti, S.P., Jann, K., Veit, R. et al. Non-caloric sweetener effects on br…
人工甘味料水は、砂糖水よりも、より空腹感をもたらすとの研究結果。本末転倒だ。。。 Chakravartti, S.P., Jann, K., Veit, R. et al. Non-caloric sweetener effects on brain appetite regulation in individuals across varying body weights. Nat Metab 7, 574–585 (2025).
RT @NatureJapan: Kathleen A. Pageらのノンカロリー甘味料が脳の食欲調節に及ぼす影響に関する@NatMetabolism #論文 Non-caloric sweetener effects on brain appetite regulation…
RT @NatureJapan: Kathleen A. Pageらのノンカロリー甘味料が脳の食欲調節に及ぼす影響に関する@NatMetabolism #論文 Non-caloric sweetener effects on brain appetite regulation…
RT @NatureJapan: Kathleen A. Pageらのノンカロリー甘味料が脳の食欲調節に及ぼす影響に関する@NatMetabolism #論文 Non-caloric sweetener effects on brain appetite regulation…
Kathleen A. Pageらのノンカロリー甘味料が脳の食欲調節に及ぼす影響に関する@NatMetabolism #論文 Non-caloric sweetener effects on brain appetite regulation in individuals across varying body weights https://t.co/dwFX7pDqSX 閲覧用リンク:https://t.co/TJsVRfEGRp @USC @uni_tue https://t.co/ZP4VdMVIji
Non-caloric sweetener effects on brain appetite regulation in individuals across varying body weights | Nature Metabolism, 4 Jul 24 https://t.co/IhvOfNONWH
Non-caloric sweetener effects on brain appetite regulation in individuals across varying body weights | Nature Metabolism https://t.co/Vt6oOct6J5 Published 26 March 2025
RT @agingdoc1: Non-caloric sweetener effects on brain appetite regulation in individuals across varying body weights https://t.co/CArzfdaW…
RT @agingdoc1: Non-caloric sweetener effects on brain appetite regulation in individuals across varying body weights “Sucralose, compared…
Non-caloric sweetener effects on brain appetite regulation in individuals across varying body weights https://t.co/CArzfdaWZT https://t.co/Gw0gmFOjsX
RT @agingdoc1: Non-caloric sweetener effects on brain appetite regulation in individuals across varying body weights “Sucralose, compared…
RT @agingdoc1: Non-caloric sweetener effects on brain appetite regulation in individuals across varying body weights “Sucralose, compared…
Non-caloric sweetener effects on brain appetite regulation in individuals across varying body weights “Sucralose, compared to sucrose and water, results in increased functional connections between the hypothalamus and brain regions involved in motivation and somatosensory
Beware diet drinks if you care about your hypothalamus and how it regulates appetite (
Non-caloric sweetener effects on brain appetite regulation in individuals across varying body weights | Nature Metabolism https://t.co/TQstTeRBGN
Non-caloric sweetener effects on brain appetite regulation in individuals across varying body weights https://t.co/GiYRVVJyIQ @NatMetabolism
レベル、空腹感にどのような変化をもたらすかを調べるため、75人の男女に対し無作為化試験を行った結果、スクラロースが空腹に関連する脳の活動を変化させ、特に肥満の人々の食欲を増進させることがわかりました。Nature Metabolism誌https://t.co/c1iBLfj86h
Non-caloric sweetener effects on brain appetite regulation in individuals across varying body weights | Nature Metabolism @DrNadolsky https://t.co/sL3J0ya2pu
Non-caloric sweetener effects on brain appetite regulation in individuals across varying body weights | Nature Metabolism https://t.co/ITLUI7TQTj
RT @NeilFlochMD: Non-caloric sweetener effects on brain appetite regulation in individuals across varying body weights | Nature Metabolism…
Non-caloric sweetener effects on brain appetite regulation in individuals across varying body weights | Nature Metabolism https://t.co/MkIuWhFi2c
RT @Brunorm84: Non-caloric sweetener effects on brain appetite regulation in individuals across varying body weights #obesity @NatMetabolis…
RT @Brunorm84: Non-caloric sweetener effects on brain appetite regulation in individuals across varying body weights #obesity @NatMetabolis…
RT @Brunorm84: Non-caloric sweetener effects on brain appetite regulation in individuals across varying body weights #obesity @NatMetabolis…
RT @Brunorm84: Non-caloric sweetener effects on brain appetite regulation in individuals across varying body weights #obesity @NatMetabolis…
Sugar substitutes make you feel more hungry? Non-caloric sweetener effects on brain appetite regulation in individuals across varying body weights | Nature Metabolism https://t.co/yE0VOZYxMe
Non-caloric sweetener effects on brain appetite regulation in individuals across varying body weights #obesity @NatMetabolism https://t.co/IMB3plqePq
RT @IsraelPodesta: Non-caloric sweetener effects on brain appetite regulation in individuals across varying body weights | @NatMetabolism…
Non-caloric sweetener effects on brain appetite regulation in individuals across varying body weights | @NatMetabolism https://t.co/sQHfXXWvyN
سوکرالوز یک شیرینکنندهی بدون کالری پرکاربرد، میتونه با تأثیر روی هیپوتالاموس حتی بدون افزایش قند خون باعث افزایش احساس گرسنگی بشه و تنظیم اشتها رو مختل کنه. مصرف شیرینکنندههای بدون کالری ممکنه برخلاف تصور، به افزایش اشتها و احتمالاً پرخوری منجر بشه. https://t.co/2kLMpRCVYq