Outcomes after fractional flow reserve-guided percutaneous coronary intervention versus coronary artery bypass grafting (FAME 3): 5-year follow-up of a multicentre, open-label, randomised trial https://t.co/a3xAnYGTOB https://t.co/ryWfDTjdsX
Outcomes after fractional flow reserve-guided percutaneous coronary intervention versus coronary artery bypass grafting (FAME 3): 5-year follow-up of a multicentre, open-label, randomised trial.
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Mar 2025 – May 2025Where it's discussed
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X / Twitter14 posts
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News8 articles
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Blogs4 articles
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YouTube3 videos
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Bluesky1 posts
AI synopsis
What people are saying
The discussions demonstrate high interest through mentions of the 5-year follow-up and overall significance of outcomes, with some comments referencing the detailed methodology and potential influence on clinical practice, showing a moderate level of engagement and recognition of impact.
Most discussions acknowledge the study results, highlighting that both PCI and CABG have similar long-term outcomes, indicating general agreement with the findings.
Participants show high interest, often referencing key aspects like 5-year follow-up and significance for treatment decisions, which suggests engagement with the clinical implications.
There are mentions of details like the trial's multicenter design and calls for further research, indicating moderate to deep engagement beyond surface-level commentary.
Some discussions emphasize the importance of the study for future clinical guidelines and practice, reflecting a moderate impact perception.
Abstract in brief
- The FAME 3 trial analyzed the long-term effectiveness of FFR-guided PCI versus CABG in patients with three-vessel coronary artery disease over a 5-year period, involving multiple hospitals across Europe, the USA, Canada, Australia, and Asia.
- Results showed no significant differences in major adverse outcomes (death, stroke, or myocardial infarction) between the PCI and CABG groups, with 16% of PCI patients and 14% of CABG patients experiencing these events by the end of the study.
- The trial's findings indicate that both treatment options have similar long-term outcomes, as the rates of death and other complications were comparable for both techniques, suggesting that advancements in care did not
Top posts
Most liked on X and BlueskyBest ACC 2025 Outcomes after fractional flow reserve-guided percutaneous coronary intervention versus coronary artery bypass grafting 5-year follow-up no significant difference in a composite outcome of death, stroke, or myocardial infarction https://t.co/UEvyCg5QIn
Outcomes after fractional flow reserve-guided percutaneous coronary intervention versus coronary artery bypass grafting (FAME 3): 5-year follow-up At the 5-year follow-up, there was no significant difference of death, stroke, or myocardial infarction https://t.co/UEvyCg5iSP
✨Great evidence summaries in a unique format! Subscribe to the YouTube channel Evidence-Based Cardiology Talks
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All mentions
Five-Year Outcomes of FFR-Guided PCI Versus CABG in Multivessel Disease
The FAME 3 trial analyzed long-term outcomes of FFR-guided PCI versus CABG in multivessel coronary artery disease over five years, showing similar rates of major adverse events for both treatments.
FAME 3 5-Year Outcomes: PCI vs CABG in Multivessel Disease
This Lancet article presents the fiveyear followup results of the FAME 3 trial. It compares fractional flow reserve-guided PCI with the latest-generation stents and coronary artery bypass grafting in patients with…
FAME 3 5-Year Follow-Up Comparing PCI and CABG Outcomes
This Lancet article presents the five-year follow-up results of the FAME 3 trial, which compared FFR-guided PCI using latest-generation stents and coronary artery bypass grafting in patients with three-vessel disease…
RT @latidoscc:
New from @TheLancet Outcomes after fractional flow reserve-guided percutaneous coronary intervention versus coronary artery bypass grafting (FAME 3) #AbbottCardiovascular #OmniWire #Philips #pressurewire contact me for reprints https://t.co/3zssYZkMU3
RT @TheLancet: Outcomes after fractional flow reserve-guided percutaneous coronary intervention versus coronary artery bypass grafting (FAM…
RT @TheLancet: Outcomes after fractional flow reserve-guided percutaneous coronary intervention versus coronary artery bypass grafting (FAM…
Outcomes after fractional flow reserve-guided percutaneous coronary intervention versus coronary artery bypass grafting (FAME 3): 5-year follow-up of a multicentre, open-label, randomised trial https://t.co/a3xAnYGTOB https://t.co/ryWfDTjdsX
✨Great evidence summaries in a unique format! Subscribe to the YouTube channel Evidence-Based Cardiology Talks
"Outcomes after fractional flow reserve-guided percutaneous coronary intervention versus coronary artery bypass grafting (FAME 3): 5-year follow-up of a multicentre, open-label, randomised trial." Publié ce jour dans @thelancet.bsky.social #MedSky #CardioSky www.thelancet.com/journals/lan...
FFRガイドのPCIはCABGと比較して死亡、脳卒中、心筋梗塞の複合アウトカムに有意差はなかった。MIや血行再建はPCIで多かった。FAME3試験。Lancet. PMID: 40174598. https://t.co/yzRUMwobqM
[Articles] Outcomes after fractional flow reserve-guided percutaneous coronary intervention versus coronary artery bypass grafting (FAME 3): 5-year follow-up of a multicentre, open-label, randomised trial https://t.co/RJrM7LyYLq
Outcomes after fractional flow reserve-guided percutaneous coronary intervention versus coronary artery bypass grafting (FAME 3): 5-year follow-up of a multicentre, open-label, randomised trial
Best ACC 2025 Outcomes after fractional flow reserve-guided percutaneous coronary intervention versus coronary artery bypass grafting 5-year follow-up no significant difference in a composite outcome of death, stroke, or myocardial infarction https://t.co/UEvyCg5QIn
[Articles] Outcomes after fractional flow reserve-guided percutaneous coronary intervention versus coronary artery bypass grafting (FAME 3): 5-year follow-up of a multicentre, open-label, randomised trial #science #publication #research #publications https://t.co/uojE3irfEK
Outcomes after fractional flow reserve-guided percutaneous coronary intervention versus coronary artery bypass grafting (FAME 3): 5-year follow-up of a multicentre, open-label, randomised trial - The Lancet https://t.co/2OTRY0zFQs
Outcomes after fractional flow reserve-guided percutaneous coronary intervention versus coronary artery bypass grafting (FAME 3): 5-year follow-up At the 5-year follow-up, there was no significant difference of death, stroke, or myocardial infarction https://t.co/UEvyCg5iSP