JAMA Psychiatry July 2025 PMID 40266625

Distinct Convergent Brain Alterations in Sleep Disorders and Sleep Deprivation: A Meta-Analysis.

Gerion M Reimann, Alireza Hoseini, Mihrican Koçak, Melissa Beste, Vincent Küppers, Ivana Rosenzweig, David Elmenhorst, Gabriel Natan Pires, Angela R Laird, Peter T Fox, Kai Spiegelhalder, Kathrin Reetz, Simon B Eickhoff, Veronika I Müller, Masoud Tahmasian

Mentions

59
Peak: 33 in Apr 2025
across 4 sources since Apr 2025

Extended reach

608,910
potential audience

Total likes

5,319

Video views

238,203

Mentions per month

Apr 2025 – Nov 2025

Where it's discussed

  • X / Twitter49 posts
  • News6 articles
  • Bluesky2 posts
  • YouTube2 videos

AI synopsis

What people are saying

Numerous posts quote specific brain regions like the subgenual anterior cingulate cortex and amygdala, showcasing the depth of the analysis. Phrases like 'distinct yet shared brain changes' and 'unique correlates' reflect a nuanced understanding of the research, contributing to an overall enthusiastic tone that emphasizes the importance of the findings and their potential impact on treatment strategies.

AgreementStrong agreement

The discussions show strong consensus regarding the findings and significance of the publication, evidenced by multiple posts echoing similar sentiments.

InterestHigh interest

Participants express high curiosity about the brain alterations related to sleep, indicating a broad relevance of the topic in various fields.

EngagementHigh engagement

Many users delve into specific brain regions highlighted in the study, discussing their implications in detail, which shows a meaningful engagement with the content.

ImpactHigh impact

The discussions suggest that the findings are perceived as having considerable implications for understanding and treating sleep disorders.

Abstract in brief

  • Sleep disorders have various underlying causes but exhibit similar symptoms, indicating shared brain mechanisms, and there is a need to explore how these mechanisms differ between chronic disorders and temporary sleep deprivation.
  • The study focuses on identifying common and distinct neural correlates in sleep disorders and sleep deprivation through a thorough review of neuroimaging research.
  • Findings from the analysis of 231 articles reveal transdiagnostic brain alterations and suggest connections between these alterations, behavioral functions, and neural connectivity patterns, highlighting the complexity of sleep's impact on brain function.

Top posts

Most liked on X and Bluesky
Masoud Tahmasian, MD. PhD.
@MasoudTahmasian · X

Our #metaanalysis (n = 231) in @JAMAPsych reveals consistent brain abnormalities across #sleep disorders involving affective and cognitive hubs in sgACC, amygdala/hippocampus Short-term sleep deprivation shows a distinct picture, affecting the thalamus https://t.co/BbGEubLG2V https://t.co/vJ0g7sjWpu

Apr 23, 2025 · 74 likes · 21 shares · 968 followers View post →
JAMA Psychiatry
@JAMAPsych · X

Distinct brain abnormalities were found in the subgenual anterior cingulate cortex, amygdala, and hippocampus in long-term sleep disorders, and in the right thalamus following short-term sleep deprivation. https://t.co/WBkWv05ATy @MasoudTahmasian https://t.co/qvxoSuZl2h

Jul 19, 2025 · 47 likes · 9 shares · 56,955 followers View post →
JAMA Psychiatry
@JAMAPsych · X

Distinct brain abnormalities were found in the subgenual anterior cingulate cortex, amygdala, and hippocampus in long-term sleep disorders, and in the right thalamus following short-term sleep deprivation. https://t.co/KdGpeyLsFD

Apr 23, 2025 · 26 likes · 6 shares · 56,955 followers View post →
SES
@Sociedad_SES · X

Los trastornos del sueño y la falta de sueño dejan diferentes huellas en el cerebro a corto y largo plazo, según un estudio. https://t.co/jYzb0pLyR3

May 5, 2025 · 7 likes · 3 shares · 2,895 followers View post →
Dra. Teraiza Mesa R Cuenta Oficial ®
@Dra_TeraizaMesa · X

Distinct brain abnormalities were found in the subgenual anterior cingulate cortex, amygdala, and hippocampus in long-term sleep disorders, and in the right thalamus following short-term sleep deprivation. https://t.co/bRsSKylbUy @MasoudTahmasian https://t.co/gW0M1J64PP

Jul 21, 2025 · 5 likes · 2 shares · 9,039 followers View post →
CLaE
@leafs_s · X

JAMA Psychiatry Distinct Convergent Brain Alterations in Sleep Disorders and Sleep Deprivation A Meta-Analysis https://t.co/p0z2DGYV6y

Apr 24, 2025 · 4 likes · 28,420 followers View post →

All mentions

ESRS
@ESRS_Sleep · X

In this week’s Sleep Science Friday: Do chronic sleep disorders and short-term sleep deprivation impact the same brain regions, or show distinct patterns? A meta-analysis led by Dr. Masoud Tahmasian synthesises 231 studies. https://t.co/OcINwbpu0b

Sep 27, 2025 · 5,686 followers View post →
lonepine
@LonepineRjr · X

RT @Dra_TeraizaMesa: Distinct brain abnormalities were found in the subgenual anterior cingulate cortex, amygdala, and hippocampus in long-…

Jul 21, 2025 · 2 shares · 873 followers View post →
Dra. Teraiza Mesa R Cuenta Oficial ®
@Dra_TeraizaMesa · X

Distinct brain abnormalities were found in the subgenual anterior cingulate cortex, amygdala, and hippocampus in long-term sleep disorders, and in the right thalamus following short-term sleep deprivation. https://t.co/bRsSKylbUy @MasoudTahmasian https://t.co/gW0M1J64PP

Jul 21, 2025 · 5 likes · 2 shares · 9,039 followers View post →
Martin Correa
@martinrafco · X

RT @JAMAPsych: Distinct brain abnormalities were found in the subgenual anterior cingulate cortex, amygdala, and hippocampus in long-term s…

Jul 19, 2025 · 9 shares · 232 followers View post →
Youhong Hu
@Phoenix57402997 · X

RT @JAMAPsych: Distinct brain abnormalities were found in the subgenual anterior cingulate cortex, amygdala, and hippocampus in long-term s…

Jul 19, 2025 · 9 shares · 220 followers View post →
De-Zhi Jin
@DezhiJin · X

RT @JAMAPsych: Distinct brain abnormalities were found in the subgenual anterior cingulate cortex, amygdala, and hippocampus in long-term s…

Jul 19, 2025 · 9 shares · 49 followers View post →
Patricio Castro (#new
@pacastrom · X

RT @JAMAPsych: Distinct brain abnormalities were found in the subgenual anterior cingulate cortex, amygdala, and hippocampus in long-term s…

Jul 19, 2025 · 9 shares · 284 followers View post →
Jamie Hanson (@jamielarsh.bsky.social)
@JamieLarsH · X

RT @JAMAPsych: Distinct brain abnormalities were found in the subgenual anterior cingulate cortex, amygdala, and hippocampus in long-term s…

Jul 19, 2025 · 9 shares · 9,675 followers View post →
JAMA Psychiatry
@JAMAPsych · X

Distinct brain abnormalities were found in the subgenual anterior cingulate cortex, amygdala, and hippocampus in long-term sleep disorders, and in the right thalamus following short-term sleep deprivation. https://t.co/WBkWv05ATy @MasoudTahmasian https://t.co/qvxoSuZl2h

Jul 19, 2025 · 47 likes · 9 shares · 56,955 followers View post →
PsychConcierge
@psychconcierge.bsky.social · Bluesky

Distinct Convergent Brain Alterations in Sleep Disorders and Sleep Deprivation

Jul 2, 2025 View post →
Masoud Tahmasian, MD. PhD.
@MasoudTahmasian · X

Was Schlafstörungen mit unserem Gehirn machen? https://t.co/6SGshqcjZx Paper: https://t.co/BbGEubLG2V #sleep #sleepdisorders #neuroimaging #metaanalysis @JAMAPsych @fzj_inm7 https://t.co/em1y7Ea5tV

May 20, 2025 · 4 likes · 968 followers View post →
お茶柱/心理学のべレスク
@otea_stalk · X

【MA】寝不足の脳機能は? 研究231件から3,380人を解析 慢性的な睡眠障害者は、感情調節や報酬処理、記憶に関わる領域で一貫した変化が確認された 短期的では、注意調節や感覚処理、覚醒に関わる領域で変化 慢性と短期で異常が重複しない https://t.co/IXQDtSp7j5

May 19, 2025 · 28 followers View post →
Shicheng Guo
@ShihchengGuo · X

Sleep disorders and sleep deprivation show distinct yet shared brain changes. Meta-analysis uncovers common neural substrates and unique correlates. PMID:40266625, JAMA Psychiatry 2025, @JAMAPsych https://t.co/AkTmQOry5a #AI #Pharma #BioMed #RNA #ASHG #ESHG

May 12, 2025 · 549 followers View post →
Javier Torres full support to
@drtowerstein · X

RT @Sociedad_SES: Los trastornos del sueño y la falta de sueño dejan diferentes huellas en el cerebro a corto y largo plazo, según un estud…

May 6, 2025 · 3 shares · 709 followers View post →
Laura Lillo Triguero
@DrL_Lillo · X

RT @Sociedad_SES: Los trastornos del sueño y la falta de sueño dejan diferentes huellas en el cerebro a corto y largo plazo, según un estud…

May 5, 2025 · 3 shares · 560 followers View post →
Dra Valentina Ochoa
@resonarte_8a · X

RT @Sociedad_SES: Los trastornos del sueño y la falta de sueño dejan diferentes huellas en el cerebro a corto y largo plazo, según un estud…

May 5, 2025 · 3 shares · 1,870 followers View post →
SES
@Sociedad_SES · X

Los trastornos del sueño y la falta de sueño dejan diferentes huellas en el cerebro a corto y largo plazo, según un estudio. https://t.co/jYzb0pLyR3

May 5, 2025 · 7 likes · 3 shares · 2,895 followers View post →
Małgorzata Czajkowska - Malinowska
@MCzMalinowska · X

May 1, 2025 · 1 like · 320 followers View post →
@guardian_xcu · X

➡️ Neu gewonnene Erkenntnisse eröffnen Möglichkeiten, die Wirkung nicht-medikamentöser und pharmakologischer Therapien bei unterschiedlichen Schlafstörungen zu vergleichen. ➡️ Der Forschungsartikel zur Arbeit Forschender des Forschungszentrums Jülich https://t.co/KC6h6PIu0S 2/2

Apr 28, 2025 · 2,331 followers View post →
octavio
@dontavo66 · X

RT @MasoudTahmasian: Our #metaanalysis (n = 231) in @JAMAPsych reveals consistent brain abnormalities across #sleep disorders involving aff…

Apr 27, 2025 · 21 shares · 331 followers View post →
drPatricioReyPsiquiatra
@drpatriciorey · X

Los #trastornos del sueño generan anomalías cerebrales que involucran centros que expresan sintomas afectivos, cognitivos y ansiedad https://t.co/TQ64qdecsS

Apr 25, 2025 · 507 followers View post →
The Iranian Neuroscientist Community (IRNSC)
@IRNSC_official · X

RT @MasoudTahmasian: Our #metaanalysis (n = 231) in @JAMAPsych reveals consistent brain abnormalities across #sleep disorders involving aff…

Apr 25, 2025 · 21 shares · 598 followers View post →
HealthSci.AI
@HealthSci_AI · X

RT @MasoudTahmasian: Our #metaanalysis (n = 231) in @JAMAPsych reveals consistent brain abnormalities across #sleep disorders involving aff…

Apr 25, 2025 · 21 shares · 2,299 followers View post →
Miguel Fermaint
@mdfermaint · X

RT @MasoudTahmasian: Our #metaanalysis (n = 231) in @JAMAPsych reveals consistent brain abnormalities across #sleep disorders involving aff…

Apr 24, 2025 · 21 shares · 8 followers View post →
Dark angel 509
@509_dark · X

RT @MasoudTahmasian: Our #metaanalysis (n = 231) in @JAMAPsych reveals consistent brain abnormalities across #sleep disorders involving aff…

Apr 24, 2025 · 21 shares · 56 followers View post →
AngryPhDstudent❗️❗️❗️
@ONNESHA092 · X

RT @MasoudTahmasian: Our #metaanalysis (n = 231) in @JAMAPsych reveals consistent brain abnormalities across #sleep disorders involving aff…

Apr 24, 2025 · 21 shares · 202 followers View post →
J Sam
@JaicSam · X

RT @MasoudTahmasian: Our #metaanalysis (n = 231) in @JAMAPsych reveals consistent brain abnormalities across #sleep disorders involving aff…

Apr 24, 2025 · 21 shares · 980 followers View post →
drPatricioReyPsiquiatra
@drpatriciorey · X

RT @MasoudTahmasian: Our #metaanalysis (n = 231) in @JAMAPsych reveals consistent brain abnormalities across #sleep disorders involving aff…

Apr 24, 2025 · 21 shares · 507 followers View post →
CLaE
@leafs_s · X

JAMA Psychiatry Distinct Convergent Brain Alterations in Sleep Disorders and Sleep Deprivation A Meta-Analysis https://t.co/p0z2DGYV6y

Apr 24, 2025 · 4 likes · 28,420 followers View post →
Wen Liu
@lwcvs1029 · X

RT @MasoudTahmasian: Our #metaanalysis (n = 231) in @JAMAPsych reveals consistent brain abnormalities across #sleep disorders involving aff…

Apr 24, 2025 · 21 shares · 26 followers View post →
Weijie Huang
@weijiehuang18 · X

RT @MasoudTahmasian: Our #metaanalysis (n = 231) in @JAMAPsych reveals consistent brain abnormalities across #sleep disorders involving aff…

Apr 24, 2025 · 21 shares · 11 followers View post →
Ziteng Han
@ZitengHan · X

RT @MasoudTahmasian: Our #metaanalysis (n = 231) in @JAMAPsych reveals consistent brain abnormalities across #sleep disorders involving aff…

Apr 24, 2025 · 21 shares · 40 followers View post →
Antonio Criscuolo
@AntoCris95 · X

RT @MasoudTahmasian: Our #metaanalysis (n = 231) in @JAMAPsych reveals consistent brain abnormalities across #sleep disorders involving aff…

Apr 24, 2025 · 21 shares · 1,193 followers View post →
David
@Foreman1David · X

RT @MasoudTahmasian: Our #metaanalysis (n = 231) in @JAMAPsych reveals consistent brain abnormalities across #sleep disorders involving aff…

Apr 24, 2025 · 21 shares · 2,111 followers View post →
Hanwen Bi
@Harvey_Bi2333 · X

RT @MasoudTahmasian: Our #metaanalysis (n = 231) in @JAMAPsych reveals consistent brain abnormalities across #sleep disorders involving aff…

Apr 24, 2025 · 21 shares · 335 followers View post →
Simon Eickhoff
@INM7_ISN · X

RT @MasoudTahmasian: Our #metaanalysis (n = 231) in @JAMAPsych reveals consistent brain abnormalities across #sleep disorders involving aff…

Apr 24, 2025 · 21 shares · 8,740 followers View post →
Jesus Ramirez-Bermudez
@JRBneuropsiq · X

RT @MasoudTahmasian: Our #metaanalysis (n = 231) in @JAMAPsych reveals consistent brain abnormalities across #sleep disorders involving aff…

Apr 24, 2025 · 21 shares · 31,367 followers View post →
Yasser Ad-Dab'bagh ياسر الدباغ
@yasseraddabbagh.bsky.social · Bluesky

Distinct Convergent Brain Alterations in Sleep Disorders and Sleep Deprivation jamanetwork.com/journals/jam...

Apr 24, 2025 · 1 like View post →
Yasser Ad-Dab'bagh
@yasseraddabbagh · X

Distinct Convergent Brain Alterations in Sleep Disorders and Sleep Deprivation https://t.co/ltszXxsZ6C

Apr 24, 2025 · 2 likes · 72,370 followers View post →
Andrea Ballesio
@_AndreaBallesio · X

RT @MasoudTahmasian: Our #metaanalysis (n = 231) in @JAMAPsych reveals consistent brain abnormalities across #sleep disorders involving aff…

Apr 24, 2025 · 21 shares · 112 followers View post →
robertaloug
@robertaloug · X

RT @JAMAPsych: Distinct brain abnormalities were found in the subgenual anterior cingulate cortex, amygdala, and hippocampus in long-term s…

Apr 23, 2025 · 6 shares · 1,872 followers View post →
Samuele Cortese
@CorteseSamuele · X

RT @MasoudTahmasian: Our #metaanalysis (n = 231) in @JAMAPsych reveals consistent brain abnormalities across #sleep disorders involving aff…

Apr 23, 2025 · 21 shares · 3,991 followers View post →
JAMA Psychiatry
@JAMAPsych · X

RT @MasoudTahmasian: Our #metaanalysis (n = 231) in @JAMAPsych reveals consistent brain abnormalities across #sleep disorders involving aff…

Apr 23, 2025 · 21 shares · 56,955 followers View post →
Wyvernsrose #RaiseTheRate
@wyvernsrose · X

RT @JAMAPsych: Distinct brain abnormalities were found in the subgenual anterior cingulate cortex, amygdala, and hippocampus in long-term s…

Apr 23, 2025 · 6 shares · 2,075 followers View post →
Zahra Moradimanesh
@zrmor · X

RT @MasoudTahmasian: Our #metaanalysis (n = 231) in @JAMAPsych reveals consistent brain abnormalities across #sleep disorders involving aff…

Apr 23, 2025 · 21 shares · 338 followers View post →
Dr. Peter A. Hall
@DrPeter_Hall · X

RT @MasoudTahmasian: Our #metaanalysis (n = 231) in @JAMAPsych reveals consistent brain abnormalities across #sleep disorders involving aff…

Apr 23, 2025 · 21 shares · 569 followers View post →
Masoud Tahmasian, MD. PhD.
@MasoudTahmasian · X

Our #metaanalysis (n = 231) in @JAMAPsych reveals consistent brain abnormalities across #sleep disorders involving affective and cognitive hubs in sgACC, amygdala/hippocampus Short-term sleep deprivation shows a distinct picture, affecting the thalamus https://t.co/BbGEubLG2V https://t.co/vJ0g7sjWpu

Apr 23, 2025 · 74 likes · 21 shares · 968 followers View post →
Ritchie Brown
@sleepwakeEEG · X

RT @JAMAPsych: Distinct brain abnormalities were found in the subgenual anterior cingulate cortex, amygdala, and hippocampus in long-term s…

Apr 23, 2025 · 6 shares · 719 followers View post →
Masoud Tahmasian, MD. PhD.
@MasoudTahmasian · X

RT @JAMAPsych: Distinct brain abnormalities were found in the subgenual anterior cingulate cortex, amygdala, and hippocampus in long-term s…

Apr 23, 2025 · 6 shares · 968 followers View post →
Comisión Investigación e Innovación Área V SESPA
@sespa5investiga · X

RT @JAMAPsych: Distinct brain abnormalities were found in the subgenual anterior cingulate cortex, amygdala, and hippocampus in long-term s…

Apr 23, 2025 · 6 shares · 645 followers View post →
JAMA Psychiatry
@JAMAPsych · X

Distinct brain abnormalities were found in the subgenual anterior cingulate cortex, amygdala, and hippocampus in long-term sleep disorders, and in the right thalamus following short-term sleep deprivation. https://t.co/KdGpeyLsFD

Apr 23, 2025 · 26 likes · 6 shares · 56,955 followers View post →
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