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Nat Med June 2025 PMID 40269333

Cognitive behavioral therapy skills via a smartphone app for subthreshold depression among adults in the community: the RESiLIENT randomized controlled trial.

Toshi A Furukawa, Aran Tajika, Rie Toyomoto, Masatsugu Sakata, Yan Luo, Masaru Horikoshi, Tatsuo Akechi, Norito Kawakami, Takeo Nakayama, Naoki Kondo, Shingo Fukuma, Ronald C Kessler, Helen Christensen, Alexis Whitton, Inbal Nahum-Shani

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Mentions

113
Peak: 87 in Apr 2025
across 5 sources since Apr 2025

Extended reach

519,878
potential audience

Total likes

456

Video views

1,434

Mentions per month

Apr 2025 – Oct 2025

Where it's discussed

  • X / Twitter95 posts
  • News12 articles
  • YouTube3 videos
  • Blogs2 articles
  • Bluesky1 posts

AI synopsis

What people are saying

The discussions express strong support and curiosity about the study, with phrases like 'a new smartphone app could help' and remarks about 'hundreds of conversations and teamwork' indicating deep engagement, while words like 'potential benefits' and 'transformative' highlight perceived high impact.

AgreementModerate agreement

Most discussions acknowledge the importance and potential benefits of the smartphone-based CBT approach for subthreshold depression, showing general support for the research outcomes.

InterestHigh interest

The discussions highlight curiosity and enthusiasm about the innovative use of digital tools for mental health, reflecting high engagement with the topic.

EngagementHigh engagement

Participants reference the significance of the trial, mention the detailed efforts involved, and emphasize its relevance, indicating deep engagement and reflection.

ImpactHigh impact

The conversations suggest that the research is seen as potentially transformative for mental health treatment, with comments about how it could 'fine-tune therapies' and the significance of the findings.

Abstract in brief

  • Subthreshold depression is common and can lead to more severe depressive episodes; CBT therapies are effective but their specific components' contributions were unclear.
  • A smartphone app was developed featuring five CBT skills, and a study recruited 3,936 adults to assess their effectiveness.
  • Results indicated that all CBT skills and their combinations significantly improved depressive symptoms compared to control conditions, highlighting the importance of understanding CBT components for future therapy design.
Read the full abstract

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坂田 昌嗣 Masa Sakata, PhD
@MasatsuguSakata · X

Apr 23, 2025 · 359 likes · 66 shares · 3,045 followers View post →
坂田 昌嗣 Masa Sakata, PhD
@MasatsuguSakata · X

Apr 25, 2025 · 25 likes · 9 shares · 3,035 followers View post →
Nature Japan
@NatureJapan · X

古川 壽亮 氏らの認知行動療法に関する＠NatureMedicine #OA #論文 Cognitive behavioral therapy skills via a smartphone app for subthreshold depression among adults in the community: the RESiLIENT randomized controlled trial https://t.co/RRm574NWdw #オープンアクセス @univkyoto https://t.co/kjgpMvuhMB

Apr 25, 2025 · 14 likes · 5 shares · 90,134 followers View post →
EARLの医学&AIノート
@EARL_med_tw · X

May 14, 2025 · 13 likes · 2 shares · 147,601 followers View post →
坂田 昌嗣 Masa Sakata, PhD
@MasatsuguSakata · X

名古屋市立大学の研究者でNature Medicineに論文がでるのは珍しい、ということで、本学医学部広報誌でRESiLIENT試験（レジトレ！）の記事が掲載されました。 https://t.co/ur3KlMyQMy https://t.co/dE2SYGY057 https://t.co/mpeq1VHWW8

Oct 25, 2025 · 11 likes · 1 share · 3,058 followers View post →
坂田 昌嗣 Masa Sakata, PhD
@MasatsuguSakata · X

Apr 25, 2025 · 11 likes · 4 shares · 3,035 followers View post →

All mentions

蚕@博論進捗報告
@Doctoral_Deg_re · X

RT @MasatsuguSakata:

Oct 25, 2025 · 66 shares · 13 followers View post →
蚕@博論進捗報告
@Doctoral_Deg_re · X

RT @MasatsuguSakata: 名古屋市立大学の研究者でNature Medicineに論文がでるのは珍しい、ということで、本学医学部広報誌でRESiLIENT試験（レジトレ！）の記事が掲載されました。 https://t.co/ur3KlMyQMy https://…

Oct 25, 2025 · 1 share · 13 followers View post →
坂田 昌嗣 Masa Sakata, PhD
@MasatsuguSakata · X

名古屋市立大学の研究者でNature Medicineに論文がでるのは珍しい、ということで、本学医学部広報誌でRESiLIENT試験（レジトレ！）の記事が掲載されました。 https://t.co/ur3KlMyQMy https://t.co/dE2SYGY057 https://t.co/mpeq1VHWW8

Oct 25, 2025 · 11 likes · 1 share · 3,058 followers View post →
Mai Masuda
@mai_masuda · X

RT @NatureJapan: 古川 壽亮 氏らの認知行動療法に関する＠NatureMedicine #OA #論文 Cognitive behavioral therapy skills via a smartphone app for subthreshold depre…

Oct 7, 2025 · 6 shares · 13 followers View post →
西山 菜々子 nanako nishiyama
@ninako75 · X

https://t.co/SD7SvNBvf2 Cognitive behavioral therapy skills via a smartphone app for subthreshold depression among adults in the community: the RESiLIENT randomized controlled trial | Nature Medicine https://t.co/DSXAJzCYtw

Sep 15, 2025 · 1 like · 218 followers View post →
rappapyonn
@reviverappapyon · X

RT @kappy09091: Cognitive behavioral therapy skills via a smartphone app for subthreshold depression among adults in the community: the RES…

Aug 23, 2025 · 1 share · 936 followers View post →
ねこぴん（They/Them）
@kappy09091 · X

Cognitive behavioral therapy skills via a smartphone app for subthreshold depression among adults in the community: the RESiLIENT randomized controlled trial 古川先生の論文、共同研究の方で役立ちそう…！ https://t.co/oEC4e6rDHC

Aug 23, 2025 · 5 likes · 1 share · 2,261 followers View post →
たやまり
@dokushorii · X

＃生殖医療 #勉強垢 うつ病に対するスマホアプリによる認知行動療法について

May 24, 2025 · 69 followers View post →
Dr. Carl Hindy
@DrCarlHindy · X

Cognitive behavioral therapy skills via a smartphone app for subthreshold depression among adults in the community: the RESiLIENT randomized controlled trial | Nature Medicine https://t.co/PgtIbMXfcR

May 21, 2025 · 2 likes · 33,188 followers View post →
C☻Chihiro
@oki_13_love · X

RT @EARL_med_tw:

May 19, 2025 · 2 shares · 54 followers View post →
EARLの医学&AIノート
@EARL_med_tw · X

May 14, 2025 · 13 likes · 2 shares · 147,601 followers View post →
Pon｜食と健康
@PonNutr · X

原著 Cognitive behavioral therapy skills via a smartphone app for subthreshold depression among adults in the community: the RESiLIENT randomized controlled trial. Nature medicine, 10.1038/s41591-025-03639-1. Advance online publication. https://t.co/7TEKbD7Gt7

May 6, 2025 · 2,614 followers View post →
あこ
@akoako00815 · X

RT @MasatsuguSakata:

Apr 30, 2025 · 66 shares · 314 followers View post →
Cocolo_sent
@Cocolo_sent · X

A new smartphone app could help fine-tune therapies for subthreshold dep... https://t.co/Kx4Ci6z1zT @YouTubeより

Apr 30, 2025 · 1 like · 1,732 followers View post →
坂田 昌嗣 Masa Sakata, PhD
@MasatsuguSakata · X

RT @NatureJapan: 古川 壽亮 氏らの認知行動療法に関する＠NatureMedicine #OA #論文 Cognitive behavioral therapy skills via a smartphone app for subthreshold depre…

Apr 27, 2025 · 5 shares · 3,045 followers View post →
田中圭介研究室（上越教育大学心理臨床コース）
@K_Tanaka_Lab · X

RT @MasatsuguSakata:

Apr 26, 2025 · 9 shares · 175 followers View post →
重松 潤 Jun Shigematsu
@JunShigematsu · X

RT @MasatsuguSakata:

Apr 26, 2025 · 9 shares · 921 followers View post →
理学療法士_海津陽一 Ph.D.
@copellist · X

■ Ref info: Furukawa et al. Cognitive behavioral therapy skills via a smartphone app for subthreshold depression among adults in the community: the RESiLIENT randomized controlled trial. Nat Med (2025) ■ Ref link: https://t.co/lrpcuLUCGg ■ Today’s full: https://t.co/0nwbbs75Lt

Apr 26, 2025 · 2 likes · 10,545 followers View post →
MO
@Ma18238890 · X

RT @MasatsuguSakata:

Apr 26, 2025 · 9 shares · 393 followers View post →
MO
@Ma18238890 · X

RT @MasatsuguSakata: It took hundreds of small conversations, weekly messages, and unwavering teamwork. Today, our RESiLIENT trial is publi…

Apr 26, 2025 · 1 share · 394 followers View post →
坂田 昌嗣 Masa Sakata, PhD
@MasatsuguSakata · X

It took hundreds of small conversations, weekly messages, and unwavering teamwork. Today, our RESiLIENT trial is published in Nature Medicine. Sometimes science is not only about data — it's about the trust we build. ▶︎ https://t.co/ur3KlMyiX0

Apr 26, 2025 · 3 likes · 1 share · 3,045 followers View post →
はやしりょうた
@Ryotah414 · X

RT @MasatsuguSakata:

Apr 26, 2025 · 66 shares · 1,574 followers View post →
日経サイエンス
@NikkeiScience · X

RT @NatureJapan: 古川 壽亮 氏らの認知行動療法に関する＠NatureMedicine #OA #論文 Cognitive behavioral therapy skills via a smartphone app for subthreshold depre…

Apr 26, 2025 · 5 shares · 70,562 followers View post →
Δt
@zimei_no_ri · X

RT @NatureJapan: 古川 壽亮 氏らの認知行動療法に関する＠NatureMedicine #OA #論文 Cognitive behavioral therapy skills via a smartphone app for subthreshold depre…

Apr 25, 2025 · 5 shares · 3,626 followers View post →
user_ittk
@user_ittk · X

RT @NatureJapan: 古川 壽亮 氏らの認知行動療法に関する＠NatureMedicine #OA #論文 Cognitive behavioral therapy skills via a smartphone app for subthreshold depre…

Apr 25, 2025 · 5 shares · 47 followers View post →
Nature Japan
@NatureJapan · X

古川 壽亮 氏らの認知行動療法に関する＠NatureMedicine #OA #論文 Cognitive behavioral therapy skills via a smartphone app for subthreshold depression among adults in the community: the RESiLIENT randomized controlled trial https://t.co/RRm574NWdw #オープンアクセス @univkyoto https://t.co/kjgpMvuhMB

Apr 25, 2025 · 14 likes · 5 shares · 90,134 followers View post →
立教大学　松永美希研究室_Matsunaga Lab.(Rikkyo Univ.)
@MatsuLab_Rikkyo · X

RT @MasatsuguSakata:

Apr 25, 2025 · 66 shares · 211 followers View post →
新川広樹 Hiroki Shinkawa
@kashiwaguin12 · X

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Apr 25, 2025 · 66 shares · 621 followers View post →
Kosuke Inoue
@ki_endoepi · X

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Apr 25, 2025 · 4 shares · 1,145 followers View post →
西山 菜々子 nanako nishiyama
@ninako75 · X

RT @MasatsuguSakata:

Apr 25, 2025 · 9 shares · 217 followers View post →
Y.N.
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Apr 25, 2025 · 4 shares · 525 followers View post →
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@VACILANDO__ · X

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Apr 25, 2025 · 9 shares · 226 followers View post →
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Apr 25, 2025 · 9 shares · 975 followers View post →
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Apr 25, 2025 · 9 shares · 2,403 followers View post →
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坂田 昌嗣 Masa Sakata, PhD
@MasatsuguSakata · X

Apr 25, 2025 · 11 likes · 4 shares · 3,035 followers View post →
坂田 昌嗣 Masa Sakata, PhD
@MasatsuguSakata · X

Apr 25, 2025 · 25 likes · 9 shares · 3,035 followers View post →
坂田 昌嗣 Masa Sakata, PhD
@MasatsuguSakata · X

A new smartphone app could help fine-tune therapies for subthreshold dep... https://t.co/aZ6YhUgbGf

Apr 25, 2025 · 2 likes · 3,035 followers View post →
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Apr 24, 2025 · 66 shares · 475 followers View post →
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Cognitive behavioral therapy skills via a smartphone app for subthreshold depression among adults in the community: the RESiLIENT randomized ->Nature | More info from EcoSearch

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