April 2025 PMID 40289060

Impact of GLP- 1 Receptor Agonist Therapy in Patients High Risk for Sarcopenia.

Zoe Memel, Stephanie L Gold, Michelle Pearlman, Alicia Muratore, Robert Martindale

Mentions

19
Peak: 10 in May 2025
across 6 sources since May 2025

Extended reach

43,299
potential audience

Total likes

48

Video views

219

Mentions per month

May 2025 – Dec 2025

Where it's discussed

  • X / Twitter10 posts
  • Instagram4 posts
  • YouTube2 videos
  • Bluesky1 posts
  • Facebook1 posts
  • Reddit1 posts

AI synopsis

What people are saying

The collection reflects a cautious and investigative tone, with someone questioning the lack of attention to mitochondrial damage and sarcopenia in the publication, using phrases like 'really hope someone is monitoring' and 'very surprised no one is talking about this.' Others mention the significance of the research on high-risk groups and potential health implications, showing an understanding of the topic's importance and an interest in future research and monitoring.

AgreementModerate agreement

Most discussions show concern and curiosity about the potential risks of muscle loss, indicating general agreement that this is an important issue.

InterestModerate interest

Posts highlight specific issues like mitochondrial damage and sarcopenia, demonstrating moderate interest in the topic.

EngagementModerate engagement

Some posters actively question current research gaps and implications, showing a moderate level of in-depth engagement.

ImpactModerate impact

The focus on potential health risks and the call for further monitoring suggest that these discussions recognize a meaningful impact on patient care and clinical considerations.

Abstract in brief

  • GLP 1 receptor agonists (GLP 1 RA) are medications that help treat chronic diseases and can lead to significant weight loss, but they may also cause loss of lean muscle mass, especially in high-risk groups.
  • Certain populations, such as older adults and those with chronic kidney, liver, or inflammatory bowel diseases, are more vulnerable to muscle loss when using GLP 1 RA, and current research is limited in understanding this impact.
  • To prevent muscle loss while using GLP 1 RA, strategies like high-protein diets and resistance training are recommended, and personalized nutrition and exercise plans should be developed; further research is needed to better understand the risks for high-risk groups.]

Top posts

Most liked on X and Bluesky
若林秀隆 (Hidetaka Wakabayashi)
@HideWakabayashi · X

Impact of GLP- 1 Receptor Agonist Therapy in Patients High Risk for Sarcopenia. サルコペニアのハイリスク患者でのGLP-1受容体作動薬の総説。多い場合、総体重減少の15‐40%が除脂肪体重。G高たんぱく質の食事と筋トレの併用で筋量減少を緩和できるかも。リハ栄養ですね https://t.co/Slyqt4Yh9l

May 1, 2025 · 28 likes · 5 shares · 15,253 followers View post →
javierbutra
@javierbutra · X

Impacto de la terapia con agonistas del receptor GLP-1 en pacientes con alto riesgo de sarcopenia #alianzametabólica https://t.co/gZf1XZ0RGd https://t.co/JDSmLeXtdx

May 1, 2025 · 13 likes · 2 shares · 14,353 followers View post →
Dr. Hugo Corrales - Endocrinología.
@hugoendocrino · X

RT @javierbutra: Impacto de la terapia con agonistas del receptor GLP-1 en pacientes con alto riesgo de sarcopenia #alianzametabólica https…

May 1, 2025 · 2 shares · 6,475 followers View post →
Gerald Commissiong
@G_Commish · X

@julialmv @bhanlon15 I really hope someone is monitoring for sarcopenia/cachexia. Very surprised no one is talking about this given the mitochondrial damage data that will be forthcoming with GLP-1 drugs. Has no one looked into this? https://t.co/7r6xZQVgAb

Nov 4, 2025 · 5,321 followers View post →
Juan Carlos Obaya
@jcobaya69 · X

RT @javierbutra: Impacto de la terapia con agonistas del receptor GLP-1 en pacientes con alto riesgo de sarcopenia #alianzametabólica https…

May 1, 2025 · 2 shares · 858 followers View post →
無為徒食(でも篭の鳥)
@ASat21492703 · X

RT @HideWakabayashi: Impact of GLP- 1 Receptor Agonist Therapy in Patients High Risk for Sarcopenia. サルコペニアのハイリスク患者でのGLP-1受容体作動薬の総説。多い場合、総体…

May 1, 2025 · 5 shares · 176 followers View post →

All mentions

Gerald Commissiong
@G_Commish · X

@julialmv @bhanlon15 I really hope someone is monitoring for sarcopenia/cachexia. Very surprised no one is talking about this given the mitochondrial damage data that will be forthcoming with GLP-1 drugs. Has no one looked into this? https://t.co/7r6xZQVgAb

Nov 4, 2025 · 5,321 followers View post →
medRxivpreprint
@medrxivpreprint.bsky.social · Bluesky

Impact of GLP-1 Receptor Agonist Therapy on Atrial Fibrillation Recurrence After Catheter Ablation in Obese Patients: A Real-World Data Analysis https://www.medrxiv.org/content/10.1101/2025.05.29.25328594v1

May 31, 2025 View post →
岩山 蟹
@CanEvoCanTher · X

RT @HideWakabayashi: Impact of GLP- 1 Receptor Agonist Therapy in Patients High Risk for Sarcopenia. サルコペニアのハイリスク患者でのGLP-1受容体作動薬の総説。多い場合、総体…

May 2, 2025 · 5 shares · 159 followers View post →
Castanea_Labo
@castanea_labo · X

RT @HideWakabayashi: Impact of GLP- 1 Receptor Agonist Therapy in Patients High Risk for Sarcopenia. サルコペニアのハイリスク患者でのGLP-1受容体作動薬の総説。多い場合、総体…

May 2, 2025 · 5 shares · 30 followers View post →
nandemo investigate
@nandemoinvesti1 · X

RT @HideWakabayashi: Impact of GLP- 1 Receptor Agonist Therapy in Patients High Risk for Sarcopenia. サルコペニアのハイリスク患者でのGLP-1受容体作動薬の総説。多い場合、総体…

May 1, 2025 · 5 shares · 156 followers View post →
北庄内食援隊
@shokuentai · X

RT @HideWakabayashi: Impact of GLP- 1 Receptor Agonist Therapy in Patients High Risk for Sarcopenia. サルコペニアのハイリスク患者でのGLP-1受容体作動薬の総説。多い場合、総体…

May 1, 2025 · 5 shares · 167 followers View post →
無為徒食(でも篭の鳥)
@ASat21492703 · X

RT @HideWakabayashi: Impact of GLP- 1 Receptor Agonist Therapy in Patients High Risk for Sarcopenia. サルコペニアのハイリスク患者でのGLP-1受容体作動薬の総説。多い場合、総体…

May 1, 2025 · 5 shares · 176 followers View post →
若林秀隆 (Hidetaka Wakabayashi)
@HideWakabayashi · X

Impact of GLP- 1 Receptor Agonist Therapy in Patients High Risk for Sarcopenia. サルコペニアのハイリスク患者でのGLP-1受容体作動薬の総説。多い場合、総体重減少の15‐40%が除脂肪体重。G高たんぱく質の食事と筋トレの併用で筋量減少を緩和できるかも。リハ栄養ですね https://t.co/Slyqt4Yh9l

May 1, 2025 · 28 likes · 5 shares · 15,253 followers View post →
Dr. Hugo Corrales - Endocrinología.
@hugoendocrino · X

RT @javierbutra: Impacto de la terapia con agonistas del receptor GLP-1 en pacientes con alto riesgo de sarcopenia #alianzametabólica https…

May 1, 2025 · 2 shares · 6,475 followers View post →
Juan Carlos Obaya
@jcobaya69 · X

RT @javierbutra: Impacto de la terapia con agonistas del receptor GLP-1 en pacientes con alto riesgo de sarcopenia #alianzametabólica https…

May 1, 2025 · 2 shares · 858 followers View post →
javierbutra
@javierbutra · X

Impacto de la terapia con agonistas del receptor GLP-1 en pacientes con alto riesgo de sarcopenia #alianzametabólica https://t.co/gZf1XZ0RGd https://t.co/JDSmLeXtdx

May 1, 2025 · 13 likes · 2 shares · 14,353 followers View post →
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