Cell June 2025 PMID 40300604

Macrophages direct location-dependent recall of B cell memory to vaccination.

Rama Dhenni, Alexandra Carey Hoppé, Arnold Reynaldi, Wunna Kyaw, Nathalie Tricia Handoko, Abigail K Grootveld, Yuki Honda Keith, Nayan Deger Bhattacharyya, Holly I Ahel, Aiden Josiah Telfser, Andrew N McCorkindale, Seyhan Yazar, Christina H T Bui, James T Smith, Weng Hua Khoo

Mentions

118
Peak: 39 in Apr 2025
across 10 sources since Apr 2025

Extended reach

405,299
potential audience

Total likes

252

Video views

18

Mentions per month

Apr 2025 – Dec 2025

Where it's discussed

  • X / Twitter48 posts
  • News31 articles
  • Facebook14 posts
  • Bluesky10 posts
  • Instagram5 posts
  • TikTok3 posts
  • Blogs3 articles
  • YouTube2 videos
  • LinkedIn1 posts
  • Reddit1 posts

AI synopsis

What people are saying

This collection reflects a high level of interest and perceived impact, with posts emphasizing practical applications like vaccine booster timing and arm choice, and some sharing the discovery that delivering boosts in the same arm can strengthen immune responses. The tone and wording convey excitement about the potential to improve vaccination outcomes and impact global health strategies.

AgreementModerate agreement

Most discussions support or acknowledge the significance of the research, especially highlighting its potential to influence vaccination strategies.

InterestHigh interest

The posts show high interest, with multiple mentions of the study’s practical implications, such as the importance of vaccination arm selection.

EngagementModerate engagement

The discussions involve detailed mentions of research findings and implications, indicating moderate to high engagement.

ImpactHigh impact

The posts suggest that this research could significantly impact vaccination approaches worldwide, emphasizing its importance for future public health strategies.

Abstract in brief

  • Vaccines create long-lasting immune cells, both plasma cells and memory B cells (Bmems), which can further evolve to improve their effectiveness when exposed again to the same antigen.
  • In mouse studies, it was found that memory B cells in draining lymph nodes — near the initial vaccination site — are more effective in generating stronger immune responses and are more likely to reintegrate into germinal centers compared to those in non-draining nodes.
  • In humans, receiving a boost of the BNT162b2 vaccine in the same arm as the first shot led to quicker antibody production and better immune cell response, highlighting the significance of specialized macrophages in controlling memory B cell activity.

Top posts

Most liked on X and Bluesky
Waggoner Lab
@LabWaggoner · X

Macrophages direct location-dependent recall of B cell memory to vaccination @CellCellPress @ramadhenni @ImmuNodeAlex @mezzam et al https://t.co/XaIfxQJS8B https://t.co/q2L3Dftv4c

Apr 29, 2025 · 108 likes · 19 shares · 11,665 followers View post →
Cell
@CellCellPress · X

In the latest issue! Macrophages direct location-dependent recall of B cell memory to vaccination https://t.co/pPZfExChxe

Jun 28, 2025 · 67 likes · 9 shares · 264,443 followers View post →
@DrJoePajak CSci CChem FRSC
@drjoepajak.bsky.social · Bluesky

Research paper, ‘Macrophages direct location-dependent recall of B cell memory to vaccination.’ Credit: Rama Dhenni et al. @cellpress.bsky.social www.cell.com/cell/fulltex...

May 5, 2025 · 17 likes · 3 shares View post →
QI 181
@QI_181 · X

Des chercheurs de Sydney révèlent que recevoir son rappel vaccinal dans le même bras stimule une réponse immunitaire plus rapide et puissante — une découverte-clé pour repenser les stratégies vaccinales mondiales. 28.04.25 https://t.co/dIFonZvca9

Apr 30, 2025 · 16 likes · 6 shares · 1,304 followers View post →
Waggoner Lab
@labwaggoner.bsky.social · Bluesky

Macrophages direct location-dependent recall of B cell memory to vaccination @cellcellpress.bsky.social @ramadhenni.bsky.social @immunodealex.bsky.social www.cell.com/cell/fulltex...

Apr 29, 2025 · 12 likes · 2 shares View post →
Cell - a Cell Press journal
@cp-cell.bsky.social · Bluesky

Now online! Macrophages direct location-dependent recall of B cell memory to vaccination

Apr 29, 2025 · 8 likes · 4 shares View post →

All mentions

priya joseph
@ayirpelle · X

RT @CellCellPress: In the latest issue! Macrophages direct location-dependent recall of B cell memory to vaccination https://t.co/pPZfExChxe

Jun 30, 2025 · 9 shares · 4,993 followers View post →
空与风 Fendy 領域展開版
@kong001x · X

RT @CellCellPress: In the latest issue! Macrophages direct location-dependent recall of B cell memory to vaccination https://t.co/pPZfExChxe

Jun 30, 2025 · 9 shares · 224 followers View post →
iArmandoVBaneado
@iArmandoVBanned · X

RT @CellCellPress: In the latest issue! Macrophages direct location-dependent recall of B cell memory to vaccination https://t.co/pPZfExChxe

Jun 29, 2025 · 9 shares · 68 followers View post →
Inmunoluna
@inmunoluna · X

RT @CellCellPress: In the latest issue! Macrophages direct location-dependent recall of B cell memory to vaccination https://t.co/pPZfExChxe

Jun 29, 2025 · 9 shares · 100 followers View post →
Hulagu
@HulaguBioChem · X

RT @CellCellPress: In the latest issue! Macrophages direct location-dependent recall of B cell memory to vaccination https://t.co/pPZfExChxe

Jun 29, 2025 · 9 shares · 1,275 followers View post →
Thamarasee Jeewandara
@Jeew333T · X

RT @CellCellPress: In the latest issue! Macrophages direct location-dependent recall of B cell memory to vaccination https://t.co/pPZfExChxe

Jun 29, 2025 · 9 shares · 1,284 followers View post →
Juan Francisco
@JuanCor43609485 · X

RT @CellCellPress: In the latest issue! Macrophages direct location-dependent recall of B cell memory to vaccination https://t.co/pPZfExChxe

Jun 29, 2025 · 9 shares · 208 followers View post →
Rudra Channappanavar
@RudraChanna07 · X

RT @CellCellPress: In the latest issue! Macrophages direct location-dependent recall of B cell memory to vaccination https://t.co/pPZfExChxe

Jun 29, 2025 · 9 shares · 129 followers View post →
Cell
@CellCellPress · X

In the latest issue! Macrophages direct location-dependent recall of B cell memory to vaccination https://t.co/pPZfExChxe

Jun 28, 2025 · 67 likes · 9 shares · 264,443 followers View post →
vaccineresearch.bsky.social
@vaccineresearch.bsky.social · Bluesky

Macrophages direct location-dependent recall of B cell memory to vaccination: Cell www.cell.com/cell/fulltex...

Jun 26, 2025 View post →
たんぽぽ
@k-hirasawa.bsky.social · Bluesky

シドニーの科学者たちは、1回目の接種と同じ腕でブースター接種を受けることで、免疫系がより迅速かつ効果的に反応することを発見しました。 www.thebrighterside.news/post/left-or... Macrophages direct location-dependent recall of B cell memory to vaccination www.cell.com/cell/fulltex...

Jun 12, 2025 View post →
Martha-JD, MBA, PCC-
@mryoung151 · X

Macrophages direct location-dependent recall of B cell memory to vaccination Vaccine boosting in the same arm promotes GC re-entry and rapid secretion of antibodies @fitterhappierAJ https://t.co/BJhspYEUAd https://t.co/TCq3K1Lme2

Jun 11, 2025 · 3 likes · 8,935 followers View post →
Astropierre
@astropierre.com · Bluesky

2/2 Le papier "Macrophages direct location-dependent recall of B cell memory to vaccination" est disponible ici : doi.org/10.1016/j.ce...

Jun 5, 2025 · 5 likes View post →
Santiago Corral
@enfermeria · X

¿Sabías que el brazo en el que te vacunas podría influir en tu inmunidad? Un estudio reciente en la revista Cell revela que la memoria inmunológica es más rápida y fuerte si las dosis de refuerzo se aplican en el mismo brazo. https://t.co/TUtYtcAWwE

May 22, 2025 · 2,945 followers View post →
旅人 tabito
@tabibito250 · X

Macrophages direct location-dependent recall of B cell memory to vaccination: Cell https://t.co/tzqZk0c2Z0

May 14, 2025 · 1 like · 1,081 followers View post →
@DrJoePajak CSci CChem FRSC
@drjoepajak.bsky.social · Bluesky

Research paper, ‘Macrophages direct location-dependent recall of B cell memory to vaccination.’ Credit: Rama Dhenni et al. @cellpress.bsky.social www.cell.com/cell/fulltex...

May 5, 2025 · 17 likes · 3 shares View post →
Allen 13
@YanConstantin · X

RT @QI_181: Des chercheurs de Sydney révèlent que recevoir son rappel vaccinal dans le même bras stimule une réponse immunitaire plus rapid…

May 1, 2025 · 6 shares · 122 followers View post →
deux années au Niger (à Niamey)
@pjd77420 · X

RT @QI_181: Des chercheurs de Sydney révèlent que recevoir son rappel vaccinal dans le même bras stimule une réponse immunitaire plus rapid…

May 1, 2025 · 6 shares · 408 followers View post →
FrLecardonnel
@FrLecardonnel · X

RT @QI_181: Des chercheurs de Sydney révèlent que recevoir son rappel vaccinal dans le même bras stimule une réponse immunitaire plus rapid…

May 1, 2025 · 6 shares · 990 followers View post →
Aleš Kralj
@Ales_Kralj14 · X

https://t.co/BRP50ShQ62

May 1, 2025 · 1,513 followers View post →
な bot
@NeuroNNNNN_bot · X

[Cell] Macrophages direct location-dependent recall of B cell memory to vaccination https://t.co/kQg73KAOSz

Apr 30, 2025 · 29 followers View post →
CROM
@CromLoupe · X

RT @QI_181: Des chercheurs de Sydney révèlent que recevoir son rappel vaccinal dans le même bras stimule une réponse immunitaire plus rapid…

Apr 30, 2025 · 6 shares · 1,528 followers View post →
Sudipta Barua
@RSuns777 · X

RT @LabWaggoner: Macrophages direct location-dependent recall of B cell memory to vaccination @CellCellPress @ramadhenni @ImmuNodeAlex @mez…

Apr 30, 2025 · 19 shares · 566 followers View post →
STEFXAV
@STEFXAV2 · X

RT @QI_181: Des chercheurs de Sydney révèlent que recevoir son rappel vaccinal dans le même bras stimule une réponse immunitaire plus rapid…

Apr 30, 2025 · 6 shares · 985 followers View post →
TOM (SAWYER)
@bibinhafc · X

RT @QI_181: Des chercheurs de Sydney révèlent que recevoir son rappel vaccinal dans le même bras stimule une réponse immunitaire plus rapid…

Apr 30, 2025 · 6 shares · 1,229 followers View post →
QI 181
@QI_181 · X

Des chercheurs de Sydney révèlent que recevoir son rappel vaccinal dans le même bras stimule une réponse immunitaire plus rapide et puissante — une découverte-clé pour repenser les stratégies vaccinales mondiales. 28.04.25 https://t.co/dIFonZvca9

Apr 30, 2025 · 16 likes · 6 shares · 1,304 followers View post →
QI 181
@QI_181 · X

@GerstmansA @StevePascolo @xazalbert @sudokuvariante @Kevin_McKernan @P_J_Buckhaults Des chercheurs de Sydney révèlent que recevoir son rappel vaccinal dans le même bras stimule une réponse immunitaire plus rapide et puissante — une découverte-clé pour repenser les stratégies vaccinales mondiales. 28.04.25 https://t.co/dIFonZuEkB

Apr 30, 2025 · 1,304 followers View post →
Ahmad_I
@khanabdoosh_ · X

RT @LabWaggoner: Macrophages direct location-dependent recall of B cell memory to vaccination @CellCellPress @ramadhenni @ImmuNodeAlex @mez…

Apr 30, 2025 · 19 shares · 109 followers View post →
Thelonevirologist
@thelonevirologist.bsky.social · Bluesky

Macrophages direct location-dependent recall of B cell memory to vaccination www.cell.com/cell/fulltex...

Apr 30, 2025 · 1 like View post →
Life Science Journal Content
@lsn_jc · X

Macrophages direct location-dependent recall of B cell memory to vaccination #science #publication #research #journal https://t.co/oAwMiUWiEc

Apr 30, 2025 · 265 followers View post →
Moxie
@MarciaMoxie · X

RT @Fla_Medic: AFD Blog `Cell: Macrophages Direct Location-Dependent Recall of B cell Memory to Vaccination' #Vaccine #Immunity https://t.c…

Apr 30, 2025 · 1 share · 445 followers View post →
Kutand Alkım Bayer
@kutandalkim · X

RT @LabWaggoner: Macrophages direct location-dependent recall of B cell memory to vaccination @CellCellPress @ramadhenni @ImmuNodeAlex @mez…

Apr 30, 2025 · 19 shares · 654 followers View post →
ferminacevesd
@ferminacevesd · X

RT @chayito09: Fuentes: https://t.co/aPETcfqX69 https://t.co/N7ys1TsDSj Artículo original https://t.co/ajY1ChidyR

Apr 30, 2025 · 1 share · 2,700 followers View post →
Mike Coston
@fla-medic.bsky.social · Bluesky

AFD Blog `Cell: Macrophages Direct Location-Dependent Recall of B cell Memory to Vaccination' #Vaccine #Immunity afludiary.blogspot.com/2025/04/cell...

Apr 30, 2025 · 3 likes · 1 share View post →
Michael Coston
@Fla_Medic · X

AFD Blog `Cell: Macrophages Direct Location-Dependent Recall of B cell Memory to Vaccination' #Vaccine #Immunity https://t.co/1KScT3cuXh

Apr 30, 2025 · 2 likes · 1 share · 5,289 followers View post →
Rosario in Paris ᥫ᭡
@chayito09 · X

Fuentes: https://t.co/aPETcfqX69 https://t.co/N7ys1TsDSj Artículo original https://t.co/ajY1ChidyR

Apr 30, 2025 · 6 likes · 1 share · 76,080 followers View post →
Being chakravarthy
@beingchakravrty · X

RT @LabWaggoner: Macrophages direct location-dependent recall of B cell memory to vaccination @CellCellPress @ramadhenni @ImmuNodeAlex @mez…

Apr 29, 2025 · 19 shares · 335 followers View post →
Patrick Reeves
@pmreeves · X

RT @LabWaggoner: Macrophages direct location-dependent recall of B cell memory to vaccination @CellCellPress @ramadhenni @ImmuNodeAlex @mez…

Apr 29, 2025 · 19 shares · 411 followers View post →
harada pat
@harapatrick · X

RT @LabWaggoner: Macrophages direct location-dependent recall of B cell memory to vaccination @CellCellPress @ramadhenni @ImmuNodeAlex @mez…

Apr 29, 2025 · 19 shares · 141 followers View post →
Melinda L Tursky
@melinda_tursky · X

RT @LabWaggoner: Macrophages direct location-dependent recall of B cell memory to vaccination @CellCellPress @ramadhenni @ImmuNodeAlex @mez…

Apr 29, 2025 · 19 shares · 1,195 followers View post →
xxy
@xxy07255392 · X

RT @LabWaggoner: Macrophages direct location-dependent recall of B cell memory to vaccination @CellCellPress @ramadhenni @ImmuNodeAlex @mez…

Apr 29, 2025 · 19 shares · 267 followers View post →
9DarianDraught8
@1DarianDraught1 · X

RT @LabWaggoner: Macrophages direct location-dependent recall of B cell memory to vaccination @CellCellPress @ramadhenni @ImmuNodeAlex @mez…

Apr 29, 2025 · 19 shares · 107 followers View post →
Clara H. Whyte
@ClaraHWhyte · X

RT @LabWaggoner: Macrophages direct location-dependent recall of B cell memory to vaccination @CellCellPress @ramadhenni @ImmuNodeAlex @mez…

Apr 29, 2025 · 19 shares · 962 followers View post →
Rahman LAB
@rahmanLAB2023 · X

RT @LabWaggoner: Macrophages direct location-dependent recall of B cell memory to vaccination @CellCellPress @ramadhenni @ImmuNodeAlex @mez…

Apr 29, 2025 · 19 shares · 219 followers View post →
triplekon
@Navaraaa · X

RT @LabWaggoner: Macrophages direct location-dependent recall of B cell memory to vaccination @CellCellPress @ramadhenni @ImmuNodeAlex @mez…

Apr 29, 2025 · 19 shares · 453 followers View post →
Jang Hyun (Jay) Park
@janghyun_park_ · X

RT @LabWaggoner: Macrophages direct location-dependent recall of B cell memory to vaccination @CellCellPress @ramadhenni @ImmuNodeAlex @mez…

Apr 29, 2025 · 19 shares · 102 followers View post →
Africa
@Africa_Gonz · X

RT @LabWaggoner: Macrophages direct location-dependent recall of B cell memory to vaccination @CellCellPress @ramadhenni @ImmuNodeAlex @mez…

Apr 29, 2025 · 19 shares · 115 followers View post →
Xiangyue Zhang
@Xiangyue_CA · X

RT @LabWaggoner: Macrophages direct location-dependent recall of B cell memory to vaccination @CellCellPress @ramadhenni @ImmuNodeAlex @mez…

Apr 29, 2025 · 19 shares · 278 followers View post →
Stephen T Yeung, PhD
@StephenTYeung · X

RT @LabWaggoner: Macrophages direct location-dependent recall of B cell memory to vaccination @CellCellPress @ramadhenni @ImmuNodeAlex @mez…

Apr 29, 2025 · 19 shares · 518 followers View post →
Frank Paul Mora
@InTime_49 · X

RT @LabWaggoner: Macrophages direct location-dependent recall of B cell memory to vaccination @CellCellPress @ramadhenni @ImmuNodeAlex @mez…

Apr 29, 2025 · 19 shares · 424 followers View post →
Rama Dhenni
@ramadhenni · X

RT @LabWaggoner: Macrophages direct location-dependent recall of B cell memory to vaccination @CellCellPress @ramadhenni @ImmuNodeAlex @mez…

Apr 29, 2025 · 19 shares · 439 followers View post →
Waggoner Lab
@labwaggoner.bsky.social · Bluesky

Macrophages direct location-dependent recall of B cell memory to vaccination @cellcellpress.bsky.social @ramadhenni.bsky.social @immunodealex.bsky.social www.cell.com/cell/fulltex...

Apr 29, 2025 · 12 likes · 2 shares View post →
Waggoner Lab
@LabWaggoner · X

Macrophages direct location-dependent recall of B cell memory to vaccination @CellCellPress @ramadhenni @ImmuNodeAlex @mezzam et al https://t.co/XaIfxQJS8B https://t.co/q2L3Dftv4c

Apr 29, 2025 · 108 likes · 19 shares · 11,665 followers View post →
Andy_Weeble_Weaver
@AndrewW66619812 · X

The paper in "Cell" the above "Nature" article is based upon, & links to: “Macrophages direct location-dependent recall of B cell memory to vaccination” 2/2 https://t.co/nxT5Yxlc2o

Apr 29, 2025 · 4,356 followers View post →
Cell - a Cell Press journal
@cp-cell.bsky.social · Bluesky

Now online! Macrophages direct location-dependent recall of B cell memory to vaccination

Apr 29, 2025 · 8 likes · 4 shares View post →
Cornelia Duncan
@unc-rn.bsky.social · Bluesky

Macrophages direct location-dependent recall of B cell memory to vaccination: Cell www.cell.com/cell/fulltex...

Apr 29, 2025 View post →
Un1v3rs0 Z3r0
@Un1v3rs0Z3r0 · X

Macrophages direct location-dependent recall of B cell memory to vaccination https://t.co/3TxVCCX04j

Apr 29, 2025 · 511 followers View post →
Marcus Robinson
@robinsonmj.bsky.social · Bluesky

Vaccination in left arm, right arm, or both?? @labphan.bsky.social congrats and looking to you for the answer

Apr 29, 2025 · 3 likes · 1 share View post →
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... boosters. Cell. 2025 doi: 10.1016/j.cell.2025.04.005 PMID: 40300604 · No photo description available.

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... boosters. Cell. 2025 doi: 10.1016/j.cell.2025.04.005 PMID: 40300604.

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The findings, published in Cell and led by ... Mee Ling Munier and Tri Giang Phan, 28 April 2025, Cell. DOI: 10.1016/j.cell.2025.04.005.

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DOI: 10.1016/j.cell.2025.04.005 External Link Copyright: © 2025 The Author(s). Published by Elsevier Inc. Highlights. • Memory B cells in the ...

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Forscher führen dies in Cell (2025; DOI: 10.1016/j. cell.2025.04.005) auf die Bildung von Gedächtnis-B- Zellen im drainierenden Lymphknoten ...

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... vaccines. Here's a link to the full study if you would like to check it out: https://doi.org/10.1016/j.cell.2025.04.005 · iualumni12. • 8mo ago.

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doi:10.1016/j.annonc.2025.04.005. Share this article. facebook share ... Assessing Recurrence Risk in Patients With Non-Clear Cell Renal Cell ...

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Macrophages direct location-dependent recall of B cell memory to vaccination. Cell 2025. DOI: 10.1016/j.cell. 2025.04.005. 林孟葳and 408 ...

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Cell, 2025; DOI: 10.1016/j.cell.2025.04.005. Cite This Page: MLA; APA; Chicago. Garvan Institute of Medical Research ...

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Macrophages direct location-dependent recall of B cell memory to vaccination. Cell 2025. DOI: 10.1016/j.cell. 2025.04.005. No photo ...

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Journal: Cell; Funder: National Health and Medical Research Council; DOI: 10.1016/j.cell.2025.04.005. Keywords. /Scientific community/Research ...

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DOI 10.1016/j.cell.2025.04.005 Sotto: Cellule B della memoria (rosse) che interagiscono con i macrofagi (bianchi) all'interno di un ...

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... Cell, doi: 10.1016/j.cell.2025.04.005. © wissenschaft.de - Claudia Krapp. Teilen: Facebook · Twitter · LinkedIn · Xing; Newsletter; Drucken.

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... Cell, ha dimostrato che i macrofagi nei ... 10.1016/j.cell.2025.04.005 Sotto: Cellule B ... cell.2025.04.005 Sotto: Cellule B della ...

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DOI 10.1016/j.cell.2025.04.005 Sotto: Cellule B della memoria (rosse) che interagiscono con i macrofagi (bianchi) all'interno di un ...

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org/10.1016/j.molcel.2025.04.005. 制版人:十一. 参考文献. 1 Mu, X. & Hur, S. Immunogenicity of In Vitro-Transcribed RNA.Acc Chem Res54, 4012 ...

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Cell 2025. DOI: 10.1016/j.cell. 2025.04.005. May be an image of text that says 'Draining lymph node Resting Capsule Draining lymph · 332. 5 ...

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... 10.1016/j.xfre.2024.09.001​:contentReference[oaicite:0]{index=0} #多嚢胞性卵巣症候群#糖尿病#健康#BMI#体重管理#思春期#PCOS#岡山二人クリニック".

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DOI 10.1016/j.cell.2025.04.005 Sotto: Cellule B della memoria (rosse) che interagiscono con i macrofagi (bianchi) all'interno di un ...

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Cell 2025. DOI: 10.1016/j.cell. 2025.04.005. May be an image of text that says 'Draining lymph node Resting Capsule Draining lymph · 周敦庸 ...

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... cell analysis.Reprod Biomed Online. 2025;51(3):104833. ・Response letter ... doi:10.1016/j.fertnstert.2025.04.005 #望妊治療 #不妊治療 ...

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doi:10.1016/j.fertnstert.2025.04.005 #望妊治療 #不妊治療 #クロミフェン #クロミッド #双子 · #多胎妊娠 #妊娠 #排卵障害 #PCOS #多のう胞性卵巣 ...

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https://doi.org/10.1016/j.fertnstert.2025.04.005. original sound ... While we await human trials and scalable cell sources, the potential of this ...

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Cell Sci. 115, 3227–3234 (2002). Crossref · PubMed · Web of Science · Google ... https://doi.org/10.1016/j.cj.2025.04.005 · Crossref. Ying Yang ...

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... Journal of Cell Science, 138, 21, (2025).https://doi.org/10.1242/jcs ... https://doi.org/10.1016/j.cj.2025.04.005 · Crossref. Ying Yang ...

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