April 2025 PMID 40301994

The overlooked trio: sleep duration, sampling time and physical exercise alter levels of olink-assessed blood biomarkers of cardiovascular risk.

Luiz Eduardo Mateus Brandão, Lei Zhang, Anastasia Grip, Mun-Gwan Hong, Emil Kåks, Rui Benfeitas, Fjola Sigurdardottir, Kaj Blennow, Henrik Zetterberg, Daniel Espes, Torbjørn Omland, Payam Emami Khoonsari, Christian Benedict, Jonathan Cedernaes

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Mentions

260

Peak: 23 in May 2025

across 6 sources since May 2025

Extended reach

594,651

potential audience

Total likes

123

Video views

1,238

Mentions per month

May 2025 – Aug 2025

Where it's discussed

News214 articles
X / Twitter32 posts
Blogs8 articles
Reddit3 posts
YouTube2 videos
Bluesky1 posts

AI synopsis

What people are saying

The discussions reflect a general consensus that sleep deprivation and physical activity significantly affect blood biomarkers related to cardiovascular risk. Several posts emphasize the importance of sleep, with phrases like 'poor sleep can increase heart disease risk' and 'even a few nights of bad sleep threaten heart health,' which demonstrate a concern for health impacts. The tone varies from informational to slightly alarmed, indicating engagement with the practical implications of the research.

AgreementModerate agreement

Most discussions acknowledge the significance of sleep, physical activity, and sampling timing, with many agreeing that these factors influence cardiovascular biomarkers.

InterestHigh interest

Posts demonstrate high curiosity, highlighting studies linking sleep deprivation with increased heart risk and emphasizing the relevance of the findings.

EngagementModerate engagement

Some comments delve into the implications and mechanisms, showing moderate to deep engagement, like mentions of inflammation and molecular pathways.

ImpactModerate impact

The discussions suggest that the publication has a noticeable but not transformative impact, primarily raising awareness about subtle influences on cardiovascular health.

Abstract in brief

This study investigated how factors like sleep duration, physical exercise, and time of day influence blood biomarkers associated with cardiovascular disease (CVD) risk, finding that these factors cause significant changes in biomarker levels.
The research showed that certain biomarkers, including IL-6 and BDNF, are affected by exercise and sleep patterns, with some profiles linked to increased future CVD risk, especially after sleep restriction.
These results emphasize the importance of considering sleep duration and daily physiological changes when assessing cardiovascular health, suggesting future research should focus on diverse populations and conditions.

Read the full abstract

All mentions

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Impact of Sleep, Exercise, and Time of Day on Blood Cardiovascular Biomarkers

This study investigates how sleep duration, physical exercise, and sampling time influence blood biomarkers related to cardiovascular risk, revealing significant variations that can affect risk assessment and health…

صحة أفضل ويب · May 28, 2025 458 views

フッ化

@flucium · X

https://t.co/sf9eWnsRKX The overlooked trio: sleep duration, sampling time and physical exercise alter levels of olink-assessed blood biomarkers of cardiovascular risk

Aug 11, 2025 · 439 followers View post →

Kevin John

@Kev_in_Science · X

RT @JCedernaes:

Aug 7, 2025 · 7 shares · 279 followers View post →

Fran Carrillo-Salinas, PhD

@FranCarrilloPhD · X

RT @JCedernaes:

Aug 7, 2025 · 7 shares · 882 followers View post →

Michal Tal, PhD

@ImmunoFever · X

RT @JCedernaes:

Aug 6, 2025 · 7 shares · 14,309 followers View post →

おくさん/OKUSUN

@Astella6174 · X

睡眠不足は心血管リスクを高める普通の睡眠（8.5時間/夜）と睡眠制限（4.25時間/夜）の条件で心血管バイオマーカー88種類を測定。わずか3晩の睡眠不足でも、心疾患リスクと関連する炎症マーカーIL-27やLGALS9が上昇 https://t.co/JBHdUP2KhO https://t.co/oH2hDUDLcq

Jul 9, 2025 · 1 like · 1,185 followers View post →

Uniliitto ry

@uniliitto · X

Uppsalan yliopiston tutkimuksessa selvitettiin, miten huonosti nukutut yöt voivat vaikuttaa jo lyhyellä aikavälillä terveyteen – ja erityisesti sydänterveyteen. Tutkimus on julkaistu Biomarker-lehdessä https://t.co/IKShYxYjXf https://t.co/UUUnpFgvrf

Jun 17, 2025 · 1 like · 110 followers View post →

Yoshi Michi

@yoshimu39 · X

Jun 15, 2025 · 2 likes · 270 followers View post →

AI/ML Innovations Inc

@AIML_Innova · X

New study shows just 3 nights of poor sleep can increase heart disease risk by 27%! Sleep deprivation triggers inflammation & stress hormones, damaging your cardiovascular system over time. Is your sleep schedule putting your heart at risk? #HealthyLife https://t.co/NYyBPTUvg7

Jun 13, 2025 · 1 like · 523 followers View post →

Digital Brain

@digitalbrain01 · X

Jun 7, 2025 · 1 followers View post →

Digital Brain

@yourdigitalbrain.bsky.social · Bluesky

Jun 7, 2025 · 5 likes View post →



@guardian_xcu · X

➡️ Die neue Studie der Universität Uppsala

Jun 4, 2025 · 2,311 followers View post →

Eduard Antoniu

@Editwit · X

https://t.co/gIR8RHJTOT

May 25, 2025 · 1,679 followers View post →

Bill Heller

@noturbine · X

RT @windwatchorg: Sleep restriction vs normal sleep resulted in a biomarker profile associated with a higher risk of heart failure, coronar…

May 23, 2025 · 1 share · 4,590 followers View post →

National Wind Watch

@windwatchorg · X

Sleep restriction vs normal sleep resulted in a biomarker profile associated with a higher risk of heart failure, coronary artery disease, and atrial fibrillation https://t.co/3flyK3aX6W

May 23, 2025 · 1 like · 1 share · 2,680 followers View post →

Bina Pattel

@BinaPattel · X

LACK OF SLEEP LINKED TO INCREASED RISK OF #CARDIOVASCULAR DISEASE – NEW STUDY https://t.co/vpt3vyBkRa EVEN A FEW NIGHTS INSUFFICIENT SLEEP IS LINKED GREATER RISK OF HEART PROBLEMS SWEDEN 50% REGULARLY EXPERIENCE DISTURBED SLEEP COMMON AMONG SHIFT WORKERS https://t.co/f7370o2art https://t.co/WoRAOZb1l7

May 22, 2025 · 36 followers View post →

Mind Your Science!

@MindYourSci · X

RT @agingdoc1: The overlooked trio: sleep duration, sampling time and physical exercise alter levels of olink-assessed blood biomarkers of…

May 14, 2025 · 2 shares · 133 followers View post →

Alice Braga

@bragaalice1 · X

RT @agingdoc1: The overlooked trio: sleep duration, sampling time and physical exercise alter levels of olink-assessed blood biomarkers of…

May 14, 2025 · 2 shares · 260 followers View post →

Agingdoc

@agingdoc1 · X

The overlooked trio: sleep duration, sampling time and physical exercise alter levels of olink-assessed blood biomarkers of cardiovascular risk https://t.co/j0VsYSqAHc https://t.co/094IUsQglg

May 14, 2025 · 10 likes · 2 shares · 41,718 followers View post →

SES

@Sociedad_SES · X

Incluso unas pocas noches sin dormir lo suficiente promueven mecanismos moleculares vinculados a un mayor riesgo de problemas cardíacos, según un nuevo estudio liderado por la Universidad de Uppsala. https://t.co/CbFloJ96Yw

May 13, 2025 · 1 like · 2,765 followers View post →

peninnah rachel

@peninnahrachel · X

RT @NeuroscienceNew: “Overlooked Trio: Sleep Duration, Sampling Time and Physical Exercise Alter Levels of Olink-Assessed Blood Biomarkers…

May 13, 2025 · 4 shares · 992 followers View post →

@SN_Oncology

@SN_Oncology · X

RT @JCedernaes:

May 12, 2025 · 7 shares · 2,286 followers View post →

hadis alhyri

@hadis_alhyri · X

RT @NeuroscienceNew: “Overlooked Trio: Sleep Duration, Sampling Time and Physical Exercise Alter Levels of Olink-Assessed Blood Biomarkers…

May 12, 2025 · 4 shares View post →

Liam Guy

@WillsAScot · X

RT @NeuroscienceNew: “Overlooked Trio: Sleep Duration, Sampling Time and Physical Exercise Alter Levels of Olink-Assessed Blood Biomarkers…

May 12, 2025 · 4 shares · 494 followers View post →

Dr. Gennadi Glinsky, MD, Ph.D.

@gglinskii · X

The overlooked trio: sleep duration, sampling time and physical exercise alter levels of olink-assessed blood biomarkers of cardiovascular risk https://t.co/He0GcYJXWI

May 12, 2025 · 1 like · 2,069 followers View post →

Dr. Gennadi Glinsky, MD, Ph.D.

@gglinskii · X

RT @NeuroscienceNew: “Overlooked Trio: Sleep Duration, Sampling Time and Physical Exercise Alter Levels of Olink-Assessed Blood Biomarkers…

May 12, 2025 · 4 shares · 2,069 followers View post →

Yoshi Michi

@yoshimu39 · X

May 12, 2025 · 2 likes · 270 followers View post →

aroc725

@aroc725 · X

https://t.co/bd0xRbDTgB

May 11, 2025 · 1,400 followers View post →

Pere Joan Sala

@Fradbius · X

Unes poques nits amb son insuficient ja promouen mecanismes moleculars relacionats amb un major risc de problemes cardíacs. https://t.co/OuNsk7c7iN

May 11, 2025 · 251 followers View post →

Neuroscience News

@NeuroscienceNew · X

May 11, 2025 · 14 likes · 4 shares · 505,663 followers View post →

Lei Zhang

@LeizhangLucky · X

RT @JCedernaes:

May 8, 2025 · 7 shares · 3 followers View post →

Longevity Leap

@LongevityLeap · X

RT @JCedernaes:

May 8, 2025 · 7 shares · 39 followers View post →

Tesla Maxie

@financialCuff · X

RT @JCedernaes:

May 8, 2025 · 7 shares · 414 followers View post →

Jonathan Cedernaes

@JCedernaes · X

May 8, 2025 · 20 likes · 7 shares · 3,126 followers View post →

The overlooked trio: sleep duration, sampling time and physical exercise alter levels of olink-assessed blood biomarkers of cardiovascular risk.

Mentions per month

Where it's discussed

What people are saying

Abstract in brief

Top posts

All mentions

Eight Daily Habits That Harm Your Health

Impact of Sleep, Exercise, and Time of Day on Blood Cardiovascular Biomarkers