Am J Med September 2025 PMID 40324552

Effects of Collagen Supplements on Skin Aging: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Seung-Kwon Myung, Yunseo Park

Mentions

107
Peak: 6 in Sep 2025
across 6 sources since Jun 2025

Extended reach

313,632
potential audience

Total likes

4,502

Video views

126,087

Mentions per month

Jun 2025 – Nov 2025

Where it's discussed

  • News83 articles
  • X / Twitter13 posts
  • YouTube3 videos
  • Facebook3 posts
  • Blogs3 articles
  • Bluesky2 posts

AI synopsis

What people are saying

The social discussions focus on the importance of rigorous scientific reviews, with comments referencing detailed meta-analyses and emphasizing how removing industry-funded or low-quality studies alters the perceived benefits of collagen. Words like 'not surprised' and references to scientific evidence underscore a critical, impactful stance, reflecting deep engagement with the research and its implications.

AgreementModerate agreement

Most discussions agree with the findings, emphasizing the importance of critical reviews that question industry claims.

InterestHigh interest

The discussions display high interest, referencing recent studies, meta-analyses, and detailed analyses of research quality.

EngagementHigh engagement

Participants engage deeply, citing specific studies, methodologies, and implications for the skincare industry.

ImpactHigh impact

The discussions highlight significant impact, challenging popular beliefs and influencing opinions on collagen supplement efficacy.

Abstract in brief

  • Collagen supplements are widely promoted for improving skin aging signs like hydration, elasticity, and wrinkles, but a comprehensive review of 23 randomized controlled trials found mixed results depending on study funding and quality.
  • Studies funded by pharmaceutical companies showed significant skin improvements, while those without funding did not, and high-quality studies found no significant effects, suggesting that the positive outcomes may be influenced by study bias.
  • Overall, there is no solid clinical evidence to support the use of collagen supplements for preventing or treating skin aging in real-world scenarios.

Top posts

Most liked on X and Bluesky
Kelly Dobos, Cosmetic Chemist
@kellydobos · X

New meta-analysis on collagen supplements. When you remove low-quality & industry-funded studies, the “benefits” for skin hydration, elasticity, & wrinkles disappear. Cosmetic scientists: *not surprised.* DOI: 10.1016/j.amjmed.2025.04.034 #SkincareScience #CosmeticChemist

Jul 7, 2025 · 3 likes · 5,494 followers View post →
Mike Hart, M.D
@drmikehart · X

Study

Jul 31, 2025 · 1 like · 66,388 followers View post →
Dr Brad Stanfield
@BradStanfieldMD · X

@jkatha27 Yes, I cover the paper Layne is discussing in his thread here: https://t.co/CijLduhIPW

Aug 27, 2025 · 1 like · 29,249 followers View post →
Texas Orthobiologics
@orthobiotx · X

Effects of Collagen Supplements on Skin Aging: A Systematic Review and Meta-Analysis of Randomized Controlled Trials - The American Journal of Medicine https://t.co/jbJpxgkXx2

Jul 6, 2025 · 1 like · 2,645 followers View post →
Kolibriethos
@kolibriethos · X

Very good example how important critical meta analyses are #skin #collagen https://t.co/nVIZah80ux

Sep 26, 2025 · 1 like · 2,058 followers View post →
Jeff Robinson, CEO and Chairman of $MRES and $RLAB
@contrariansmind · X

“No Evidence to Support the Use of Collagen Supplements” https://t.co/1hrg43bmGf via @YouTube

Aug 13, 2025 · 56,225 followers View post →

All mentions

Klaatu
@iamklaatu · X

This is how you do that type of videos. #Physionic https://t.co/aCSwHqHnbR

Sep 26, 2025 · 159 followers View post →
Darlene
@Done00710063 · X

https://t.co/6F4b2HMktQ

Sep 26, 2025 · 15,785 followers View post →
Kolibriethos
@kolibriethos · X

Very good example how important critical meta analyses are #skin #collagen https://t.co/nVIZah80ux

Sep 26, 2025 · 1 like · 2,058 followers View post →
Kolibriethos
@kolibriethos.bsky.social · Bluesky

Very good example how important critical meta analyses are #skin #collagen youtu.be/WDhi-tcymmQ?...

Sep 26, 2025 View post →
お茶柱/心理学のべレスク
@otea_stalk · X

【MA】コラーゲンサプリは美肌に効く? RCT23件から1,474人を解析 コラーゲンサプリを飲むと、肌の弾力・保湿・シワ改善に効果がある 特に魚由来で顕著 女性に有効性が高い https://t.co/jx0YK295iS

Sep 5, 2025 · 22 followers View post →
Dr Brad Stanfield
@BradStanfieldMD · X

@jkatha27 Yes, I cover the paper Layne is discussing in his thread here: https://t.co/CijLduhIPW

Aug 27, 2025 · 1 like · 29,249 followers View post →
tallndorky
@tallndorky · X

@luisjgomez The latest study on collagen, that’s not paid for by industry, showed that collagen doesn’t do any of the things the industry says it does. https://t.co/fn3nKplmCm

Aug 15, 2025 · 8 followers View post →
Jeff Robinson, CEO and Chairman of $MRES and $RLAB
@contrariansmind · X

“No Evidence to Support the Use of Collagen Supplements” https://t.co/1hrg43bmGf via @YouTube

Aug 13, 2025 · 56,225 followers View post →
Herbert_J_Mann
@Herbert_J_Mann · X

“No Evidence to Support the Use of Collagen Supplements” - YouTube https://t.co/6BRHFdHE7i

Aug 12, 2025 · 9,218 followers View post →
Mike Hart, M.D
@drmikehart · X

Study

Jul 31, 2025 · 1 like · 66,388 followers View post →
وَدود
@vaedood · X

@Paniz_j https://t.co/pe7CREwalG https://t.co/YO2fks2DzA

Jul 31, 2025 · 68 followers View post →
Kelly Dobos, Cosmetic Chemist
@kellydobos · X

New meta-analysis on collagen supplements. When you remove low-quality & industry-funded studies, the “benefits” for skin hydration, elasticity, & wrinkles disappear. Cosmetic scientists: *not surprised.* DOI: 10.1016/j.amjmed.2025.04.034 #SkincareScience #CosmeticChemist

Jul 7, 2025 · 3 likes · 5,494 followers View post →
Kelly A. Dobos
@kellydobos.bsky.social · Bluesky

New meta-analysis on collagen supplements. When you remove low-quality & industry-funded studies, the “benefits” for skin hydration, elasticity, & wrinkles disappear. Cosmetic scientists: *not surprised.* DOI: 10.1016/j.amjmed.2025.04.034 #SkincareScience #EvidenceBasedBeauty #CosmeticChemist

Jul 7, 2025 View post →
Texas Orthobiologics
@orthobiotx · X

Effects of Collagen Supplements on Skin Aging: A Systematic Review and Meta-Analysis of Randomized Controlled Trials - The American Journal of Medicine https://t.co/jbJpxgkXx2

Jul 6, 2025 · 1 like · 2,645 followers View post →
Leonel Amaya - Nutricionista
@LeonelNutricion · X

@FITrebelde @el_itacazo Este es más reciente https://t.co/0UV8WhYtBE

Jun 7, 2025 · 227 followers View post →