J Clin Invest May 2025 PMID 40371645

Traffic jam in lung capillaries: inter-organ communication impedes gas exchange after acute kidney injury.

Ulrich Matt, Susanne Herold

Mentions

13
Peak: 7 in Jun 2025
across 3 sources since May 2025

Extended reach

120,167
potential audience

Total likes

52

Video views

26

Mentions per month

May 2025 – Jun 2025

Where it's discussed

  • X / Twitter10 posts
  • Bluesky2 posts
  • YouTube1 videos

AI synopsis

What people are saying

The discussions reflect a high level of interest and agreement, with posts describing the lung capillary 'traffic jam' as a significant discovery that impedes gas exchange following AKI; phrases like 'inter-organ communication' and references to commentaries suggest a deep engagement and acknowledgment of its potential clinical importance.

AgreementModerate agreement

Most discussions express support or approval of the study's findings, highlighting its significance.

InterestHigh interest

The posts demonstrate high curiosity and engagement with the topic, emphasizing its novelty and importance.

EngagementModerate engagement

Participants reference commentaries and provide links, indicating active involvement and a desire to discuss implications.

ImpactHigh impact

The emphasis on the study's potential for advancing diagnostics and treatment shows recognition of its high impact on medical science.

Abstract in brief

  • Acute kidney injury (AKI) often occurs in critically ill patients and triggers inflammation that can lead to lung injury, worsening patient outcomes.
  • The study by Komaru et al used advanced microscopy in mice to observe rapid accumulation of immune cells, like neutrophils and monocytes, in lung capillaries after AKI, which slowed blood flow and impaired gas exchange.
  • Interrupting this process improved oxygen levels, suggesting new possibilities for diagnostic and therapeutic strategies to prevent lung damage following AKI.

Top posts

Most liked on X and Bluesky
Journal of Clinical Investigation
@jclinicalinvest · X

ICYMI: Traffic jam in lung capillaries: Inter-organ communication impedes gas exchange after acute kidney injury: https://t.co/6aT6UZkXPO Ulrich Matt and @HeroldSusa @HeroldLab provide a Commentary on Komaru et al. (https://t.co/Ee5O0nVTyG) https://t.co/lvAUk5eWSS

Jun 1, 2025 · 23 likes · 5 shares · 50,970 followers View post →
Journal of Clinical Investigation
@jclinicalinvest · X

Traffic jam in lung capillaries: Inter-organ communication impedes gas exchange after acute kidney injury: https://t.co/6aT6UZkXPO Ulrich Matt and @HeroldSusa @HeroldLab provide a Commentary on Komaru et al. (https://t.co/Ee5O0nVTyG) https://t.co/nCYVlJ3L0m

May 30, 2025 · 23 likes · 3 shares · 50,970 followers View post →
Journal of Clinical Investigation
@jci.org · Bluesky

Traffic jam in lung capillaries: Inter-organ communication impedes gas exchange after acute kidney injury: buff.ly/ZdgF7bC @heroldlab.bsky.social provide a Commentary on Komaru et al. (buff.ly/WelaHkQ)

May 30, 2025 · 4 likes · 1 share View post →
Rene Sugar
@renesugar · X

RT @jclinicalinvest: ICYMI: Traffic jam in lung capillaries: Inter-organ communication impedes gas exchange after acute kidney injury: http…

Jun 1, 2025 · 5 shares · 3,970 followers View post →
Daniel Coyne
@DrDanMO · X

RT @jclinicalinvest: ICYMI: Traffic jam in lung capillaries: Inter-organ communication impedes gas exchange after acute kidney injury: http…

Jun 1, 2025 · 5 shares · 3,471 followers View post →
Carmen De Miguel, PhD, MS, FAHA
@Carmendemigue12 · X

RT @jclinicalinvest: ICYMI: Traffic jam in lung capillaries: Inter-organ communication impedes gas exchange after acute kidney injury: http…

Jun 1, 2025 · 5 shares · 3,360 followers View post →

All mentions

diacavan
@diacavan · X

RT @jclinicalinvest: ICYMI: Traffic jam in lung capillaries: Inter-organ communication impedes gas exchange after acute kidney injury: http…

Jun 1, 2025 · 5 shares · 165 followers View post →
Rene Sugar
@renesugar · X

RT @jclinicalinvest: ICYMI: Traffic jam in lung capillaries: Inter-organ communication impedes gas exchange after acute kidney injury: http…

Jun 1, 2025 · 5 shares · 3,970 followers View post →
Daniel Coyne
@DrDanMO · X

RT @jclinicalinvest: ICYMI: Traffic jam in lung capillaries: Inter-organ communication impedes gas exchange after acute kidney injury: http…

Jun 1, 2025 · 5 shares · 3,471 followers View post →
Tobias B. Huber
@Tobias_B_Huber · X

RT @jclinicalinvest: ICYMI: Traffic jam in lung capillaries: Inter-organ communication impedes gas exchange after acute kidney injury: http…

Jun 1, 2025 · 5 shares · 1,501 followers View post →
Carmen De Miguel, PhD, MS, FAHA
@Carmendemigue12 · X

RT @jclinicalinvest: ICYMI: Traffic jam in lung capillaries: Inter-organ communication impedes gas exchange after acute kidney injury: http…

Jun 1, 2025 · 5 shares · 3,360 followers View post →
Journal of Clinical Investigation
@jci.org · Bluesky

ICYMI: Traffic jam in lung capillaries: Inter-organ communication impedes gas exchange after acute kidney injury: buff.ly/3a2ff5u @heroldlab.bsky.social provide a Commentary on Komaru et al. (buff.ly/PmoTvZG)

Jun 1, 2025 View post →
Journal of Clinical Investigation
@jclinicalinvest · X

ICYMI: Traffic jam in lung capillaries: Inter-organ communication impedes gas exchange after acute kidney injury: https://t.co/6aT6UZkXPO Ulrich Matt and @HeroldSusa @HeroldLab provide a Commentary on Komaru et al. (https://t.co/Ee5O0nVTyG) https://t.co/lvAUk5eWSS

Jun 1, 2025 · 23 likes · 5 shares · 50,970 followers View post →
Fouad Chebib, MD, FASN
@fouadchebib · X

RT @jclinicalinvest: Traffic jam in lung capillaries: Inter-organ communication impedes gas exchange after acute kidney injury: https://t.c…

May 31, 2025 · 3 shares · 2,365 followers View post →
soda_troubles,https://med-mastodon.com/@haysam
@set_fortess · X

RT @jclinicalinvest: Traffic jam in lung capillaries: Inter-organ communication impedes gas exchange after acute kidney injury: https://t.c…

May 30, 2025 · 3 shares · 2,550 followers View post →
綿¹⁰⁰%
@LSRFortessa_X20 · X

RT @jclinicalinvest: Traffic jam in lung capillaries: Inter-organ communication impedes gas exchange after acute kidney injury: https://t.c…

May 30, 2025 · 3 shares · 734 followers View post →
Journal of Clinical Investigation
@jclinicalinvest · X

Traffic jam in lung capillaries: Inter-organ communication impedes gas exchange after acute kidney injury: https://t.co/6aT6UZkXPO Ulrich Matt and @HeroldSusa @HeroldLab provide a Commentary on Komaru et al. (https://t.co/Ee5O0nVTyG) https://t.co/nCYVlJ3L0m

May 30, 2025 · 23 likes · 3 shares · 50,970 followers View post →
Journal of Clinical Investigation
@jci.org · Bluesky

Traffic jam in lung capillaries: Inter-organ communication impedes gas exchange after acute kidney injury: buff.ly/ZdgF7bC @heroldlab.bsky.social provide a Commentary on Komaru et al. (buff.ly/WelaHkQ)

May 30, 2025 · 4 likes · 1 share View post →