Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1FSMQERF Editorial: Methotrexate as Initial Therapy for Symptomatic Pulmonary Sarcoidosis? https://t.co/SD8ix5qLqe #ATS2025 | @atscommunity https://t.co/isWQE7yn1y
First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate.
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May 2025 – Sep 2025Where it's discussed
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X / Twitter154 posts
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News14 articles
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Bluesky9 posts
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YouTube2 videos
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Blogs2 articles
AI synopsis
What people are saying
Several discussions highlight the trial's findings, such as the statement, 'Methotrexate was noninferior to prednisone regarding lung function,' showcasing users' engagement with the study's key points. Additionally, expressions like 'Wow! Can we get away from prednisone for another one of our diseases?' illustrate the excitement and potential for change in treatment protocols, influencing the overall positive sentiment around the publication.
The discussions reflected a general support for the study's findings, with many acknowledging the effectiveness of methotrexate compared to prednisone.
Many participants expressed a keen interest in both the results and implications of the trial, evident from the questions and calls for further discussion.
The depth of engagement was high, with numerous posts evaluating the methodological aspects and potential implications of the treatment options, facilitating rich conversations.
There is a consensus that the publication may significantly influence treatment approaches in pulmonary sarcoidosis, as several users commented on its relevance to clinical practice.
Abstract in brief
- Prednisone is the first-line treatment for pulmonary sarcoidosis but comes with several side effects, while methotrexate is the second-line option with fewer side effects but slower action.
- A noninferiority trial involving 138 patients compared the effects of prednisone and methotrexate on lung function at 24 weeks, finding that methotrexate's efficacy was comparable to that of prednisone.
- Both treatment groups experienced similar adverse events, with prednisone leading to weight gain and insomnia, while methotrexate was associated with nausea and fatigue.
Top posts
Most liked on X and BlueskyNEJM: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate ⏩MTX noninferior to prednisone for 1st-line treatment ⏩Similar lung function outcomes week 24. ⏩fewer side effects. ⏩ Could guide treatment choice (selected patients) https://t.co/pRebB1G1LM https://t.co/PuqL84i8HA
Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1FSMQERF Editorial: Methotrexate as Initial Therapy for Symptomatic Pulmonary Sarcoidosis? https://t.co/SD8ix5qLqe #Pulmonology #CriticalCare https://t.co/wZjAjemm4C
Wow! Can we get away from prednisone for another one of our diseases?: Pulmonary #sarcoid. This article showed MTX to be noninferior to prednisone! I know which drug I would want!: https://t.co/I1mjKe6Y99
PREDMETH Trial. Multicenter RCT MTX vs GC as first line Rx in Pulmonar #Sarcoid. MTX 15-25mg [6.11] non-inferior to prednislone 40mg [6.75] re: % change in FVC between baseline & W24. Baseline FVC mild, Combination thereby not assessed & no placebo group. https://t.co/thdBqbFZbO https://t.co/FuJrfhmnjZ
肺サルコイドーシスの初期治療:メトトレキサート vs プレドニゾン、RCT(NEJM 2025) ✅24週後の予測FVC改善は両群で6%、メトトレキサートは非劣性達成 ✅副作用発現率は両群で同等、体重増加・不眠・食欲増加など ✅軽症例やステロイド副作用懸念例に選択肢として有用 https://t.co/X5XKD3pK02
All mentions
Comparing Prednisone and Methotrexate for Sarcoidosis Treatment
Prednisone is the first-line treatment for pulmonary sarcoidosis, but comes with significant side effects. This video explores a trial comparing prednisone with methotrexate, showing similar lung function outcomes but…
Comparative Efficacy of Methotrexate and Prednisone in Sarcoidosis
Welcome to This Week in Pulmonary and Critical Care Medicine. In this episode, we discuss a noninferiority trial comparing methotrexate and prednisone for treating pulmonary sarcoidosis. Both treatments showed…
Prednisone vs. Methotrexate for 1st-line pulmonary sarcoidosis: Open-label trial shows methotrexate has fewer side effects. Intrigued? PMID:40387020, N Engl J Med 2025, @NEJM https://doi.org/10.1056/NEJMoa2501443 #Medsky #Pharmsky #RNA #ASHG #ESHG
Prednisone vs. Methotrexate for 1st-line pulmonary sarcoidosis: Open-label trial shows methotrexate has fewer side effects. Intrigued? PMID:40387020, N Engl J Med 2025, @NEJM https://t.co/ZnliDuX4sz #AI #Pharma #BioMed #RNA #ASHG #ESHG
RT @Yohei_Kanzawa: サルコイドーシス、治療難しいですよね。こんなRCTがまだ組まれるんですね。数集まるのがすごい。 First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methot…
サルコイドーシス、治療難しいですよね。こんなRCTがまだ組まれるんですね。数集まるのがすごい。 First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate | New England Journal of Medicine https://t.co/l0OpS2SBxm
サルコイドーシス、こんなRCTがまだ組まれるんですね。数集まるのがすごい。 First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate | New England Journal of Medicine www.nejm.org/doi/full/10....
New episode: This Week in PCCM STIMULUS Trial – Diaphragm neurostimulation in the ICU Prognostication & uncertainty in critical illness PREDMETH Trial – MTX vs prednisone in sarcoidosis ERS/ATS 2025 ILD classification update https://t.co/AG708DM4PS #Pulmonary #CriticalCare #ICU
This doesn't affect $ATYR ph3 readout but recent trial in NEJM on MTX vs. prednisone is relevant. Comments/editorial say that this study supports MTX combo to lower maintenance steroid dosage. https://t.co/vY0WPaZ6Fb
RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…
RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…
RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…
RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…
RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…
RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…
RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…
RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…
RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…
RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…
RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…
RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…
RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…
RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…
RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…
RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…
Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1FSMQERF Editorial: Methotrexate as Initial Therapy for Symptomatic Pulmonary Sarcoidosis? https://t.co/SD8ix5qLqe #Pulmonology #CriticalCare https://t.co/wZjAjemm4C
In the PREDMETH trial, first-line treatment of pulmonary sarcoidosis with methotrexate was noninferior to that with prednisone regarding the change at 24 weeks in the percentage of the predicted forced vital capacity. Full trial results and Research Summary: nej.md/4kdaf0o #MedSky #PulmSky
First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate https://t.co/5tb0NBKQgw
RT @rheum_showa: 肺サルコイドーシスの初期治療:メトトレキサート vs プレドニゾン、RCT(NEJM 2025) ✅24週後の予測FVC改善は両群で6%、メトトレキサートは非劣性達成 ✅副作用発現率は両群で同等、体重増加・不眠・食欲増加など ✅軽症例やステロイ…
RT @rheum_showa: 肺サルコイドーシスの初期治療:メトトレキサート vs プレドニゾン、RCT(NEJM 2025) ✅24週後の予測FVC改善は両群で6%、メトトレキサートは非劣性達成 ✅副作用発現率は両群で同等、体重増加・不眠・食欲増加など ✅軽症例やステロイ…
RT @rheum_showa: 肺サルコイドーシスの初期治療:メトトレキサート vs プレドニゾン、RCT(NEJM 2025) ✅24週後の予測FVC改善は両群で6%、メトトレキサートは非劣性達成 ✅副作用発現率は両群で同等、体重増加・不眠・食欲増加など ✅軽症例やステロイ…
肺サルコイドーシスの初期治療:メトトレキサート vs プレドニゾン、RCT(NEJM 2025) ✅24週後の予測FVC改善は両群で6%、メトトレキサートは非劣性達成 ✅副作用発現率は両群で同等、体重増加・不眠・食欲増加など ✅軽症例やステロイド副作用懸念例に選択肢として有用 https://t.co/X5XKD3pK02
First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate by Drs. Kahlmann, Wijsenbeek et al. www.nejm.org/doi/full/10.... Treatment with MTX was noninferior to prednisone with regard to the change from baseline to week 24 in the percentage of the predicted FVC.
First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate by Drs. Kahlmann, Wijsenbeek et al. https://t.co/fNudo8k0ny Treatment with MTX was noninferior to prednisone with regard to the change from baseline to week 24 in the percentage of the predicted FVC. https://t.co/oGW4qecWvd
RT @NEJM: New in the July 17, 2025, issue of NEJM: Perioperative Durvalumab in Gastric Cancer (MATTERHORN phase 3 trial) https://t.co/M3…
New in the July 17, 2025, issue of NEJM: Perioperative Durvalumab in Gastric Cancer (MATTERHORN phase 3 trial) https://t.co/M3OvPmSMEQ Prednisone or Methotrexate in Pulmonary Sarcoidosis (PREDMETH trial) https://t.co/1K1FSMQERF Cyclophosphamide and Cyclosporin for GVHD https://t.co/kCMFUjrb6X
“First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate.” Publié ce jour dans le @nejm. #MedSky www.nejm.org/doi/full/10....
RT @R_A_Vishwakarma: “Could a current second-line therapy, methotrexate, be equally effective as steroids, perhaps with fewer adverse event…
“Could a current second-line therapy, methotrexate, be equally effective as steroids, perhaps with fewer adverse events for pulmonary sarcoidosis” | NEJM https://t.co/ljzd0tkqKi
RT @NeumologiaHR: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate | New England Journal of Medicine https://t…
RT @NeumologiaHR: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate | New England Journal of Medicine https://t…
First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate | New England Journal of Medicine https://t.co/6BJgw0kxFA
https://t.co/LfwDLtvHyQ
RT @autoinMI_tauli: NEJM: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate ⏩MTX noninferior to prednisone for…
RT @LastManStand85: PREDMETH Trial. Multicenter RCT MTX vs GC as first line Rx in Pulmonar #Sarcoid. MTX 15-25mg [6.11] non-inferior to pre…
RT @LastManStand85: PREDMETH Trial. Multicenter RCT MTX vs GC as first line Rx in Pulmonar #Sarcoid. MTX 15-25mg [6.11] non-inferior to pre…
RT @LastManStand85: PREDMETH Trial. Multicenter RCT MTX vs GC as first line Rx in Pulmonar #Sarcoid. MTX 15-25mg [6.11] non-inferior to pre…
RT @LastManStand85: PREDMETH Trial. Multicenter RCT MTX vs GC as first line Rx in Pulmonar #Sarcoid. MTX 15-25mg [6.11] non-inferior to pre…
RT @LastManStand85: PREDMETH Trial. Multicenter RCT MTX vs GC as first line Rx in Pulmonar #Sarcoid. MTX 15-25mg [6.11] non-inferior to pre…
RT @LastManStand85: PREDMETH Trial. Multicenter RCT MTX vs GC as first line Rx in Pulmonar #Sarcoid. MTX 15-25mg [6.11] non-inferior to pre…
RT @LastManStand85: PREDMETH Trial. Multicenter RCT MTX vs GC as first line Rx in Pulmonar #Sarcoid. MTX 15-25mg [6.11] non-inferior to pre…
RT @LastManStand85: PREDMETH Trial. Multicenter RCT MTX vs GC as first line Rx in Pulmonar #Sarcoid. MTX 15-25mg [6.11] non-inferior to pre…
RT @LastManStand85: PREDMETH Trial. Multicenter RCT MTX vs GC as first line Rx in Pulmonar #Sarcoid. MTX 15-25mg [6.11] non-inferior to pre…
RT @LastManStand85: PREDMETH Trial. Multicenter RCT MTX vs GC as first line Rx in Pulmonar #Sarcoid. MTX 15-25mg [6.11] non-inferior to pre…
RT @LastManStand85: PREDMETH Trial. Multicenter RCT MTX vs GC as first line Rx in Pulmonar #Sarcoid. MTX 15-25mg [6.11] non-inferior to pre…
PREDMETH Trial. Multicenter RCT MTX vs GC as first line Rx in Pulmonar #Sarcoid. MTX 15-25mg [6.11] non-inferior to prednislone 40mg [6.75] re: % change in FVC between baseline & W24. Baseline FVC mild, Combination thereby not assessed & no placebo group. https://t.co/thdBqbFZbO https://t.co/FuJrfhmnjZ
RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…
RT @lupuscyclopedia: Wow! Can we get away from prednisone for another one of our diseases?: Pulmonary #sarcoid. This article showed MTX to…
プレドニゾンまたはメトトレキサートによる肺サルコイドーシスの第一選択治療 | ニューイングランド・ジャーナル・オブ・メディシン https://t.co/ZYhnpCY4a8
RT @lupuscyclopedia: Wow! Can we get away from prednisone for another one of our diseases?: Pulmonary #sarcoid. This article showed MTX to…
RT @lupuscyclopedia: Wow! Can we get away from prednisone for another one of our diseases?: Pulmonary #sarcoid. This article showed MTX to…
RT @lupuscyclopedia: Wow! Can we get away from prednisone for another one of our diseases?: Pulmonary #sarcoid. This article showed MTX to…
RT @lupuscyclopedia: Wow! Can we get away from prednisone for another one of our diseases?: Pulmonary #sarcoid. This article showed MTX to…
RT @lupuscyclopedia: Wow! Can we get away from prednisone for another one of our diseases?: Pulmonary #sarcoid. This article showed MTX to…
RT @lupuscyclopedia: Wow! Can we get away from prednisone for another one of our diseases?: Pulmonary #sarcoid. This article showed MTX to…
RT @lupuscyclopedia: Wow! Can we get away from prednisone for another one of our diseases?: Pulmonary #sarcoid. This article showed MTX to…
RT @lupuscyclopedia: Wow! Can we get away from prednisone for another one of our diseases?: Pulmonary #sarcoid. This article showed MTX to…
RT @lupuscyclopedia: Wow! Can we get away from prednisone for another one of our diseases?: Pulmonary #sarcoid. This article showed MTX to…
RT @lupuscyclopedia: Wow! Can we get away from prednisone for another one of our diseases?: Pulmonary #sarcoid. This article showed MTX to…
RT @lupuscyclopedia: Wow! Can we get away from prednisone for another one of our diseases?: Pulmonary #sarcoid. This article showed MTX to…
Wow! Can we get away from prednisone for another one of our diseases?: Pulmonary #sarcoid. This article showed MTX to be noninferior to prednisone! I know which drug I would want!: https://t.co/I1mjKe6Y99
Wow! Can we get away from prednisone for another one of our diseases?: Pulmonary sarcoid. This article showed MTX to be noninferior to prednisone! I know which drug I would want!: https://t.co/I1mjKe6Y99
未治療の肺サルコイドーシスに対するPSLとMTXの比較。 ベースラインから24週時までの%FVCは非劣性。 ただMTXは週15mgから開始、4週ごとに5mgずつ増量し最大投与量は週25mgというなかなかの高容量。日本人はもっと少なくともいいし、日本人データは欲しいところ https://t.co/UILHm0REOA
RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…
Methotrexate proved as effective as prednisone for treating pulmonary sarcoidosis, with potentially fewer side effects. by Kahlmann V, Janssen Bonás M (...) Wijsenbeek MS et 20 al. in N Engl J Med #MedSky
Methotrexate proved as effective as prednisone for treating pulmonary sarcoidosis, with potentially fewer side effects. by Kahlmann V, Janssen Bonás M (...) Wijsenbeek MS et 20 al. in N Engl J Med https://t.co/GRo8AmghFs #MedX #MedResearch
First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate | New England Journal of Medicine https://t.co/rchfyZMTNc
Should methotrexate replace prednisone as first-line treatment for pulmonary sarcoidosis? Let the debate begin. Full Article: https://t.co/JIrzZIcQ8H
RT @JesusLoarce: References: ▶️ https://t.co/ujff3sOfZb ▶️ https://t.co/USfUaBJyQO ▶️ https://t.co/LCxecJjpfk
肺サルコイドーシスの一次治療 ステロイドと比較してMTXでの治療が非劣性 (24wまでしかみていないので副作用の評価は要注意) https://t.co/t2AhWnQ34f
EvidenceAlerts | First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate. www.evidencealerts.com/Social/Artic...
References: ▶️ https://t.co/ujff3sOfZb ▶️ https://t.co/USfUaBJyQO ▶️ https://t.co/LCxecJjpfk
治療適応のある肺サルコイドーシスに対するMTXをPSLと比較した非劣勢試験。24週時点での%FVC変化で非劣勢達成。 PSLは40mgから4w毎に10mgまで減量、MTXは15mg/wから最大25mgまで増量。有害事象はそれぞれの既知のやつが出てる感じ。 Patient-Reported Outcomeも2群で同程度。 https://t.co/cjzstdnGMD
Tratamiento de primera línea de sarcoidosis pulmonar, prednisona o metotrexato 1 DOI: 10.1056/NEJMoa2501443
#PREDMETH: 1L Treatment of #PulmonarySarcoidosis with #Prednisone or #Methotrexate #NEJM #ATS2025 https://t.co/hphkuMHIvK
RT @autoinMI_tauli: NEJM: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate ⏩MTX noninferior to prednisone for…
¿Por fin una alternativa a la prednisona como 1ª línea en la #sarcoidosis pulmonar?
RT @autoinMI_tauli: NEJM: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate ⏩MTX noninferior to prednisone for…
RT @autoinMI_tauli: NEJM: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate ⏩MTX noninferior to prednisone for…
RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…
RT @autoinMI_tauli: NEJM: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate ⏩MTX noninferior to prednisone for…
RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…
RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…
RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…
RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…
RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…
RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…
RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…
RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…
RT @autoinMI_tauli: NEJM: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate ⏩MTX noninferior to prednisone for…
RT @KaminskiMed: Wow! Just in time for #ATS2025 - First Sarcoidosis RCT @NEJM this century is out - Methotrexate is equal to Prednisone…
RT @autoinMI_tauli: NEJM: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate ⏩MTX noninferior to prednisone for…
RT @autoinMI_tauli: NEJM: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate ⏩MTX noninferior to prednisone for…
RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…
RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…
RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…
RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…
RT @KaminskiMed: Wow! Just in time for #ATS2025 - First Sarcoidosis RCT @NEJM this century is out - Methotrexate is equal to Prednisone…
RT @autoinMI_tauli: NEJM: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate ⏩MTX noninferior to prednisone for…
RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…
RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…
RT @autoinMI_tauli: NEJM: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate ⏩MTX noninferior to prednisone for…
RT @autoinMI_tauli: NEJM: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate ⏩MTX noninferior to prednisone for…
RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…
RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…
RT @autoinMI_tauli: NEJM: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate ⏩MTX noninferior to prednisone for…
RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…
RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…
RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…
RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…
RT @nebetake: 肺サルコイドーシスへのステロイド vs MTXのRCT Primary endpointのFVC改善においてMTXはステロイドに非劣性。副作用の内容は薬剤ごとに異なる。 心サルコイドーシスでもステロイドが1stですが、MTXが使われることもあるので気…
RT @nebetake: 肺サルコイドーシスへのステロイド vs MTXのRCT Primary endpointのFVC改善においてMTXはステロイドに非劣性。副作用の内容は薬剤ごとに異なる。 心サルコイドーシスでもステロイドが1stですが、MTXが使われることもあるので気…
RT @autoinMI_tauli: NEJM: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate ⏩MTX noninferior to prednisone for…
RT @nebetake: 肺サルコイドーシスへのステロイド vs MTXのRCT Primary endpointのFVC改善においてMTXはステロイドに非劣性。副作用の内容は薬剤ごとに異なる。 心サルコイドーシスでもステロイドが1stですが、MTXが使われることもあるので気…
肺サルコイドーシスへのステロイド vs MTXのRCT Primary endpointのFVC改善においてMTXはステロイドに非劣性。副作用の内容は薬剤ごとに異なる。 心サルコイドーシスでもステロイドが1stですが、MTXが使われることもあるので気になるところです https://t.co/W6Khcl0ISH
RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…
RT @HadjadjJerome: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate https://t.co/uX7ywaIFi8
RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…
RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…
RT @autoinMI_tauli: NEJM: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate ⏩MTX noninferior to prednisone for…
RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…
RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…
RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…
RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…
RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…
RT @autoinMI_tauli: NEJM: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate ⏩MTX noninferior to prednisone for…
RT @KaminskiMed: Wow! Just in time for #ATS2025 - First Sarcoidosis RCT @NEJM this century is out - Methotrexate is equal to Prednisone…
RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…
RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…
RT @autoinMI_tauli: NEJM: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate ⏩MTX noninferior to prednisone for…
RT @autoinMI_tauli: NEJM: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate ⏩MTX noninferior to prednisone for…
RT @autoinMI_tauli: NEJM: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate ⏩MTX noninferior to prednisone for…
RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…
RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…
RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…
RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…
RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…
RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…
RT @autoinMI_tauli: NEJM: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate ⏩MTX noninferior to prednisone for…
RT @autoinMI_tauli: NEJM: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate ⏩MTX noninferior to prednisone for…
RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…
RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…
RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…
First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate | New England Journal of Medicine https://t.co/foYWldIwpu
RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…
RT @autoinMI_tauli: NEJM: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate ⏩MTX noninferior to prednisone for…
RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…
Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1FSMQERF Editorial: Methotrexate as Initial Therapy for Symptomatic Pulmonary Sarcoidosis? https://t.co/SD8ix5qLqe #ATS2025 | @atscommunity https://t.co/isWQE7yn1y
NEJM: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate ⏩MTX noninferior to prednisone for 1st-line treatment ⏩Similar lung function outcomes week 24. ⏩fewer side effects. ⏩ Could guide treatment choice (selected patients) https://t.co/pRebB1G1LM https://t.co/PuqL84i8HA
RT @HadjadjJerome: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate https://t.co/uX7ywaIFi8
First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate https://t.co/uX7ywaIFi8
First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate | New England Journal of Medicine https://t.co/rchfyZNrCK
First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate | New England Journal of Medicine www.nejm.org/doi/full/10....
First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate : Initial treatment with MTX was noninferior to that with prednisone with regard to the change from baseline to week 24 in the percentage of the predicted FVC https://t.co/6mb62QxEae
In the PREDMETH trial, first-line treatment of pulmonary sarcoidosis with methotrexate was noninferior to that with prednisone regarding the change at 24 weeks in the percentage of the predicted forced vital capacity. Full trial results: nej.md/4kdaf0o #ATS2025 @atscommunity.bsky.social