N Engl J Med July 2025 PMID 40387020

First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate.

Vivienne Kahlmann, Montse Janssen Bonás, Catharina C Moor, Jan C Grutters, Rémy L M Mostard, Henricus N A J van Rijswijk, Jan van der Maten, Emiel R Marges, Linda A A Moonen, Maria J Overbeek, Bart Koopman, Daan W Loth, Esther J Nossent, Michiel Wagenaar, Henk Kramer

Mentions

181
Peak: 93 in May 2025
across 5 sources since May 2025

Extended reach

3,074,357
potential audience

Total likes

498

Video views

234

Mentions per month

May 2025 – Sep 2025

Where it's discussed

  • X / Twitter154 posts
  • News14 articles
  • Bluesky9 posts
  • YouTube2 videos
  • Blogs2 articles

AI synopsis

What people are saying

Several discussions highlight the trial's findings, such as the statement, 'Methotrexate was noninferior to prednisone regarding lung function,' showcasing users' engagement with the study's key points. Additionally, expressions like 'Wow! Can we get away from prednisone for another one of our diseases?' illustrate the excitement and potential for change in treatment protocols, influencing the overall positive sentiment around the publication.

AgreementModerate agreement

The discussions reflected a general support for the study's findings, with many acknowledging the effectiveness of methotrexate compared to prednisone.

InterestHigh interest

Many participants expressed a keen interest in both the results and implications of the trial, evident from the questions and calls for further discussion.

EngagementHigh engagement

The depth of engagement was high, with numerous posts evaluating the methodological aspects and potential implications of the treatment options, facilitating rich conversations.

ImpactHigh impact

There is a consensus that the publication may significantly influence treatment approaches in pulmonary sarcoidosis, as several users commented on its relevance to clinical practice.

Abstract in brief

  • Prednisone is the first-line treatment for pulmonary sarcoidosis but comes with several side effects, while methotrexate is the second-line option with fewer side effects but slower action.
  • A noninferiority trial involving 138 patients compared the effects of prednisone and methotrexate on lung function at 24 weeks, finding that methotrexate's efficacy was comparable to that of prednisone.
  • Both treatment groups experienced similar adverse events, with prednisone leading to weight gain and insomnia, while methotrexate was associated with nausea and fatigue.

Top posts

Most liked on X and Bluesky
NEJM
@NEJM · X

Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1FSMQERF Editorial: Methotrexate as Initial Therapy for Symptomatic Pulmonary Sarcoidosis? https://t.co/SD8ix5qLqe #ATS2025 | @atscommunity https://t.co/isWQE7yn1y

May 19, 2025 · 141 likes · 52 shares · 935,642 followers View post →
Autoinmunes Medicina Interna Parc Taulí
@autoinMI_tauli · X

NEJM: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate ⏩MTX noninferior to prednisone for 1st-line treatment ⏩Similar lung function outcomes week 24. ⏩fewer side effects. ⏩ Could guide treatment choice (selected patients) https://t.co/pRebB1G1LM https://t.co/PuqL84i8HA

May 19, 2025 · 59 likes · 23 shares · 1,120 followers View post →
NEJM
@NEJM · X

Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1FSMQERF Editorial: Methotrexate as Initial Therapy for Symptomatic Pulmonary Sarcoidosis? https://t.co/SD8ix5qLqe #Pulmonology #CriticalCare https://t.co/wZjAjemm4C

Jul 22, 2025 · 52 likes · 18 shares · 935,642 followers View post →
Donald Thomas, MD
@lupuscyclopedia · X

Wow! Can we get away from prednisone for another one of our diseases?: Pulmonary #sarcoid. This article showed MTX to be noninferior to prednisone! I know which drug I would want!: https://t.co/I1mjKe6Y99

Jun 2, 2025 · 33 likes · 13 shares · 5,713 followers View post →
Rheuma Doc
@LastManStand85 · X

PREDMETH Trial. Multicenter RCT MTX vs GC as first line Rx in Pulmonar #Sarcoid. MTX 15-25mg [6.11] non-inferior to prednislone 40mg [6.75] re: % change in FVC between baseline & W24. Baseline FVC mild, Combination thereby not assessed & no placebo group. https://t.co/thdBqbFZbO https://t.co/FuJrfhmnjZ

Jun 20, 2025 · 31 likes · 13 shares · 4,032 followers View post →
昭和医科大学病院リウマチ膠原病内科 Div Rheumatol, Showa Med U
@rheum_showa · X

肺サルコイドーシスの初期治療:メトトレキサート vs プレドニゾン、RCT(NEJM 2025) ✅24週後の予測FVC改善は両群で6%、メトトレキサートは非劣性達成 ✅副作用発現率は両群で同等、体重増加・不眠・食欲増加など ✅軽症例やステロイド副作用懸念例に選択肢として有用 https://t.co/X5XKD3pK02

Jul 17, 2025 · 29 likes · 4 shares · 3,051 followers View post →

All mentions

Shicheng Guo
@shihcheng.bsky.social · Bluesky

Prednisone vs. Methotrexate for 1st-line pulmonary sarcoidosis: Open-label trial shows methotrexate has fewer side effects. Intrigued? PMID:40387020, N Engl J Med 2025, @NEJM https://doi.org/10.1056/NEJMoa2501443 #Medsky #Pharmsky #RNA #ASHG #ESHG

Sep 26, 2025 · 2 likes · 1 share View post →
Shicheng Guo
@ShihchengGuo · X

Prednisone vs. Methotrexate for 1st-line pulmonary sarcoidosis: Open-label trial shows methotrexate has fewer side effects. Intrigued? PMID:40387020, N Engl J Med 2025, @NEJM https://t.co/ZnliDuX4sz #AI #Pharma #BioMed #RNA #ASHG #ESHG

Sep 26, 2025 · 2 likes · 499 followers View post →
あっきー
@moto_moto_moto · X

RT @Yohei_Kanzawa: サルコイドーシス、治療難しいですよね。こんなRCTがまだ組まれるんですね。数集まるのがすごい。 First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methot…

Sep 2, 2025 · 1 share · 1,199 followers View post →
官澤洋平 YK Hospitalist
@Yohei_Kanzawa · X

サルコイドーシス、治療難しいですよね。こんなRCTがまだ組まれるんですね。数集まるのがすごい。 First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate | New England Journal of Medicine https://t.co/l0OpS2SBxm

Sep 2, 2025 · 11 likes · 1 share · 3,205 followers View post →
Yohei Kanzawa Hospitalist
@yohei-kanzawa.bsky.social · Bluesky

サルコイドーシス、こんなRCTがまだ組まれるんですね。数集まるのがすごい。 First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate | New England Journal of Medicine www.nejm.org/doi/full/10....

Sep 2, 2025 · 1 like View post →
Ala Eddin Sagar
@AlaEddinSagar · X

New episode: This Week in PCCM STIMULUS Trial – Diaphragm neurostimulation in the ICU Prognostication & uncertainty in critical illness PREDMETH Trial – MTX vs prednisone in sarcoidosis ERS/ATS 2025 ILD classification update https://t.co/AG708DM4PS #Pulmonary #CriticalCare #ICU

Aug 9, 2025 · 1,008 followers View post →
Dr. S
@drsprs · X

This doesn't affect $ATYR ph3 readout but recent trial in NEJM on MTX vs. prednisone is relevant. Comments/editorial say that this study supports MTX combo to lower maintenance steroid dosage. https://t.co/vY0WPaZ6Fb

Jul 25, 2025 · 13 likes · 1 share · 2,126 followers View post →
yangluchan
@yangluchant · X

RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…

Jul 23, 2025 · 18 shares · 2 followers View post →
Massimo Romano
@dottmasroman · X

RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…

Jul 23, 2025 · 18 shares · 357 followers View post →
Allergy up to date
@allergyuptodate · X

RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…

Jul 23, 2025 · 18 shares · 1,291 followers View post →
AngryPhDstudent❗️❗️❗️
@ONNESHA092 · X

RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…

Jul 23, 2025 · 18 shares · 182 followers View post →
Dr.Ezhil Mugunthan
@Ezhil_mugunthan · X

RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…

Jul 23, 2025 · 18 shares · 60 followers View post →
Jorge Luis Quintero MD. MSc.
@jquinteromd · X

RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…

Jul 23, 2025 · 18 shares · 1,935 followers View post →
Ali ihsan OLUK
@KasosMete · X

RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…

Jul 23, 2025 · 18 shares · 555 followers View post →
Fahad Alawfi
@fahadmemo · X

RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…

Jul 22, 2025 · 18 shares · 199 followers View post →
Rodrigo Dias
@RODDRIGODIAS · X

RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…

Jul 22, 2025 · 18 shares · 450 followers View post →
mocchi
@mocchi_ym · X

RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…

Jul 22, 2025 · 18 shares · 216 followers View post →
Jordan FatCat
@ParkLover_JA · X

RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…

Jul 22, 2025 · 18 shares · 25 followers View post →
ACSH
@ACSHorg · X

RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…

Jul 22, 2025 · 18 shares · 6,742 followers View post →
José Mª Gª Quintana
@jose_g_quintana · X

RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…

Jul 22, 2025 · 18 shares · 846 followers View post →
Hatim Raffaa
@HatimRaffaa · X

RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…

Jul 22, 2025 · 18 shares · 20 followers View post →
Rejoice Iiyambo
@Hilda_Iiyambo · X

RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…

Jul 22, 2025 · 18 shares · 392 followers View post →
Carmelo Espinosa M.D.
@carmelografo · X

RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…

Jul 22, 2025 · 18 shares · 639 followers View post →
NEJM
@NEJM · X

Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1FSMQERF Editorial: Methotrexate as Initial Therapy for Symptomatic Pulmonary Sarcoidosis? https://t.co/SD8ix5qLqe #Pulmonology #CriticalCare https://t.co/wZjAjemm4C

Jul 22, 2025 · 52 likes · 18 shares · 935,642 followers View post →
NEJM.org
@nejm.org · Bluesky

In the PREDMETH trial, first-line treatment of pulmonary sarcoidosis with methotrexate was noninferior to that with prednisone regarding the change at 24 weeks in the percentage of the predicted forced vital capacity. Full trial results and Research Summary: nej.md/4kdaf0o #MedSky #PulmSky

Jul 21, 2025 · 11 likes · 6 shares View post →
Jeremy Farrar
@JeremyFarrar · X

First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate https://t.co/5tb0NBKQgw

Jul 19, 2025 · 1 like · 76,121 followers View post →
がたいがでかい
@gataigadekai · X

RT @rheum_showa: 肺サルコイドーシスの初期治療:メトトレキサート vs プレドニゾン、RCT(NEJM 2025) ✅24週後の予測FVC改善は両群で6%、メトトレキサートは非劣性達成 ✅副作用発現率は両群で同等、体重増加・不眠・食欲増加など ✅軽症例やステロイ…

Jul 19, 2025 · 4 shares · 414 followers View post →
近藤 雅人
@mkondo_showa · X

RT @rheum_showa: 肺サルコイドーシスの初期治療:メトトレキサート vs プレドニゾン、RCT(NEJM 2025) ✅24週後の予測FVC改善は両群で6%、メトトレキサートは非劣性達成 ✅副作用発現率は両群で同等、体重増加・不眠・食欲増加など ✅軽症例やステロイ…

Jul 18, 2025 · 4 shares · 1,646 followers View post →
∴あくてむら∵
@collakidallergy · X

RT @rheum_showa: 肺サルコイドーシスの初期治療:メトトレキサート vs プレドニゾン、RCT(NEJM 2025) ✅24週後の予測FVC改善は両群で6%、メトトレキサートは非劣性達成 ✅副作用発現率は両群で同等、体重増加・不眠・食欲増加など ✅軽症例やステロイ…

Jul 17, 2025 · 4 shares · 1,841 followers View post →
昭和医科大学病院リウマチ膠原病内科 Div Rheumatol, Showa Med U
@rheum_showa · X

肺サルコイドーシスの初期治療:メトトレキサート vs プレドニゾン、RCT(NEJM 2025) ✅24週後の予測FVC改善は両群で6%、メトトレキサートは非劣性達成 ✅副作用発現率は両群で同等、体重増加・不眠・食欲増加など ✅軽症例やステロイド副作用懸念例に選択肢として有用 https://t.co/X5XKD3pK02

Jul 17, 2025 · 29 likes · 4 shares · 3,051 followers View post →
markusathome
@markusathome.bsky.social · Bluesky

First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate by Drs. Kahlmann, Wijsenbeek et al. www.nejm.org/doi/full/10.... Treatment with MTX was noninferior to prednisone with regard to the change from baseline to week 24 in the percentage of the predicted FVC.

Jul 17, 2025 · 3 likes · 1 share View post →
markusathome
@MarkusAtHome · X

First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate by Drs. Kahlmann, Wijsenbeek et al. https://t.co/fNudo8k0ny Treatment with MTX was noninferior to prednisone with regard to the change from baseline to week 24 in the percentage of the predicted FVC. https://t.co/oGW4qecWvd

Jul 17, 2025 · 1 like · 116 followers View post →
Wero
@FELIXSANCHEZQ · X

RT @NEJM: New in the July 17, 2025, issue of NEJM: Perioperative Durvalumab in Gastric Cancer (MATTERHORN phase 3 trial) https://t.co/M3…

Jul 17, 2025 · 1 share · 5,170 followers View post →
NEJM
@NEJM · X

New in the July 17, 2025, issue of NEJM: Perioperative Durvalumab in Gastric Cancer (MATTERHORN phase 3 trial) https://t.co/M3OvPmSMEQ Prednisone or Methotrexate in Pulmonary Sarcoidosis (PREDMETH trial) https://t.co/1K1FSMQERF Cyclophosphamide and Cyclosporin for GVHD https://t.co/kCMFUjrb6X

Jul 17, 2025 · 23 likes · 1 share · 935,642 followers View post →
BaladoCritique : club de lecture médical
@baladocritique.bsky.social · Bluesky

“First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate.” Publié ce jour dans le @nejm. #MedSky www.nejm.org/doi/full/10....

Jul 17, 2025 View post →
Prasoon Kumar Gupta
@PrasoonKumarGu4 · X

RT @R_A_Vishwakarma: “Could a current second-line therapy, methotrexate, be equally effective as steroids, perhaps with fewer adverse event…

Jul 17, 2025 · 1 share · 117 followers View post →
Ram Vishwakarma
@R_A_Vishwakarma · X

“Could a current second-line therapy, methotrexate, be equally effective as steroids, perhaps with fewer adverse events for pulmonary sarcoidosis” | NEJM https://t.co/ljzd0tkqKi

Jul 16, 2025 · 2 likes · 1 share · 893 followers View post →
Leslie Vargas-Ramírez
@lilo1278 · X

RT @NeumologiaHR: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate | New England Journal of Medicine https://t…

Jun 29, 2025 · 2 shares · 2,449 followers View post →
William
@Milligw · X

RT @NeumologiaHR: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate | New England Journal of Medicine https://t…

Jun 28, 2025 · 2 shares · 252 followers View post →
Unidad de Neumología HR
@NeumologiaHR · X

First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate | New England Journal of Medicine https://t.co/6BJgw0kxFA

Jun 28, 2025 · 4 likes · 2 shares · 1,265 followers View post →
Ripon Ahammed, MD
@Ri_Med7 · X

https://t.co/LfwDLtvHyQ

Jun 25, 2025 · 11 followers View post →
Harsha Boppana
@harsha_boppana · X

RT @autoinMI_tauli: NEJM: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate ⏩MTX noninferior to prednisone for…

Jun 25, 2025 · 23 shares · 27 followers View post →
Mohammad Aleidi
@aleidimed · X

RT @LastManStand85: PREDMETH Trial. Multicenter RCT MTX vs GC as first line Rx in Pulmonar #Sarcoid. MTX 15-25mg [6.11] non-inferior to pre…

Jun 21, 2025 · 13 shares · 295 followers View post →
Omer
@omersharif9 · X

RT @LastManStand85: PREDMETH Trial. Multicenter RCT MTX vs GC as first line Rx in Pulmonar #Sarcoid. MTX 15-25mg [6.11] non-inferior to pre…

Jun 21, 2025 · 13 shares · 594 followers View post →
Najia X.
@najaxth · X

RT @LastManStand85: PREDMETH Trial. Multicenter RCT MTX vs GC as first line Rx in Pulmonar #Sarcoid. MTX 15-25mg [6.11] non-inferior to pre…

Jun 21, 2025 · 13 shares · 170 followers View post →
Geyser of Unique Idea
@shell_salon · X

RT @LastManStand85: PREDMETH Trial. Multicenter RCT MTX vs GC as first line Rx in Pulmonar #Sarcoid. MTX 15-25mg [6.11] non-inferior to pre…

Jun 20, 2025 · 13 shares · 9 followers View post →
ong beng hooi
@ongbenghooi1 · X

RT @LastManStand85: PREDMETH Trial. Multicenter RCT MTX vs GC as first line Rx in Pulmonar #Sarcoid. MTX 15-25mg [6.11] non-inferior to pre…

Jun 20, 2025 · 13 shares · 534 followers View post →
Carlos Dueñas
@CarlosJ_Duenas · X

RT @LastManStand85: PREDMETH Trial. Multicenter RCT MTX vs GC as first line Rx in Pulmonar #Sarcoid. MTX 15-25mg [6.11] non-inferior to pre…

Jun 20, 2025 · 13 shares · 455 followers View post →
hamadh asad
@HamadhAsad40543 · X

RT @LastManStand85: PREDMETH Trial. Multicenter RCT MTX vs GC as first line Rx in Pulmonar #Sarcoid. MTX 15-25mg [6.11] non-inferior to pre…

Jun 20, 2025 · 13 shares · 13 followers View post →
Dr M Nazibur Rahman, MD (Rheumatology)
@NaziburM · X

RT @LastManStand85: PREDMETH Trial. Multicenter RCT MTX vs GC as first line Rx in Pulmonar #Sarcoid. MTX 15-25mg [6.11] non-inferior to pre…

Jun 20, 2025 · 13 shares · 702 followers View post →
Almansour
@malmansour81 · X

RT @LastManStand85: PREDMETH Trial. Multicenter RCT MTX vs GC as first line Rx in Pulmonar #Sarcoid. MTX 15-25mg [6.11] non-inferior to pre…

Jun 20, 2025 · 13 shares · 208 followers View post →
Nouf Al hemmadi
@NoufAhmedAlham2 · X

RT @LastManStand85: PREDMETH Trial. Multicenter RCT MTX vs GC as first line Rx in Pulmonar #Sarcoid. MTX 15-25mg [6.11] non-inferior to pre…

Jun 20, 2025 · 13 shares · 1,274 followers View post →
Sayantan Mukherjee
@hopelessweirdo · X

RT @LastManStand85: PREDMETH Trial. Multicenter RCT MTX vs GC as first line Rx in Pulmonar #Sarcoid. MTX 15-25mg [6.11] non-inferior to pre…

Jun 20, 2025 · 13 shares · 502 followers View post →
Rheuma Doc
@LastManStand85 · X

PREDMETH Trial. Multicenter RCT MTX vs GC as first line Rx in Pulmonar #Sarcoid. MTX 15-25mg [6.11] non-inferior to prednislone 40mg [6.75] re: % change in FVC between baseline & W24. Baseline FVC mild, Combination thereby not assessed & no placebo group. https://t.co/thdBqbFZbO https://t.co/FuJrfhmnjZ

Jun 20, 2025 · 31 likes · 13 shares · 4,032 followers View post →
お公家
@ring_lion_ · X

RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…

Jun 8, 2025 · 52 shares · 366 followers View post →
ong beng hooi
@ongbenghooi1 · X

RT @lupuscyclopedia: Wow! Can we get away from prednisone for another one of our diseases?: Pulmonary #sarcoid. This article showed MTX to…

Jun 4, 2025 · 13 shares · 534 followers View post →
キムリン@FL_PPMM(BA.1)P(XBB.1.5)
@lapin214_gn · X

プレドニゾンまたはメトトレキサートによる肺サルコイドーシスの第一選択治療 | ニューイングランド・ジャーナル・オブ・メディシン https://t.co/ZYhnpCY4a8

Jun 3, 2025 · 739 followers View post →
Kathy
@drkathy23 · X

RT @lupuscyclopedia: Wow! Can we get away from prednisone for another one of our diseases?: Pulmonary #sarcoid. This article showed MTX to…

Jun 3, 2025 · 13 shares · 268 followers View post →
Kimberley
@MollyDu127 · X

RT @lupuscyclopedia: Wow! Can we get away from prednisone for another one of our diseases?: Pulmonary #sarcoid. This article showed MTX to…

Jun 3, 2025 · 13 shares · 286 followers View post →
Abraham
@AbrahamAubry · X

RT @lupuscyclopedia: Wow! Can we get away from prednisone for another one of our diseases?: Pulmonary #sarcoid. This article showed MTX to…

Jun 3, 2025 · 13 shares · 2,144 followers View post →
AngryPhDstudent❗️❗️❗️
@ONNESHA092 · X

RT @lupuscyclopedia: Wow! Can we get away from prednisone for another one of our diseases?: Pulmonary #sarcoid. This article showed MTX to…

Jun 3, 2025 · 13 shares · 182 followers View post →
KM 007
@karam_aldeeb · X

RT @lupuscyclopedia: Wow! Can we get away from prednisone for another one of our diseases?: Pulmonary #sarcoid. This article showed MTX to…

Jun 3, 2025 · 13 shares · 4 followers View post →
Durga Prasanna Misra
@DurgaPrasannaM1 · X

RT @lupuscyclopedia: Wow! Can we get away from prednisone for another one of our diseases?: Pulmonary #sarcoid. This article showed MTX to…

Jun 3, 2025 · 13 shares · 2,339 followers View post →
Justin Dambaza
@justin_dambaza · X

RT @lupuscyclopedia: Wow! Can we get away from prednisone for another one of our diseases?: Pulmonary #sarcoid. This article showed MTX to…

Jun 3, 2025 · 13 shares · 423 followers View post →
ArianeK
@arianek · X

RT @lupuscyclopedia: Wow! Can we get away from prednisone for another one of our diseases?: Pulmonary #sarcoid. This article showed MTX to…

Jun 2, 2025 · 13 shares · 4,363 followers View post →
soda_troubles,https://med-mastodon.com/@haysam
@set_fortess · X

RT @lupuscyclopedia: Wow! Can we get away from prednisone for another one of our diseases?: Pulmonary #sarcoid. This article showed MTX to…

Jun 2, 2025 · 13 shares · 2,544 followers View post →
Nahid Hasan, MD.
@TheNerdyMedico · X

RT @lupuscyclopedia: Wow! Can we get away from prednisone for another one of our diseases?: Pulmonary #sarcoid. This article showed MTX to…

Jun 2, 2025 · 13 shares · 612 followers View post →
Upasana Agrawal
@UpasanaAgrawal_ · X

RT @lupuscyclopedia: Wow! Can we get away from prednisone for another one of our diseases?: Pulmonary #sarcoid. This article showed MTX to…

Jun 2, 2025 · 13 shares · 600 followers View post →
Donald Thomas, MD
@lupuscyclopedia · X

Wow! Can we get away from prednisone for another one of our diseases?: Pulmonary #sarcoid. This article showed MTX to be noninferior to prednisone! I know which drug I would want!: https://t.co/I1mjKe6Y99

Jun 2, 2025 · 33 likes · 13 shares · 5,713 followers View post →
Donald Thomas, MD
@lupuscyclopedia · X

Wow! Can we get away from prednisone for another one of our diseases?: Pulmonary sarcoid. This article showed MTX to be noninferior to prednisone! I know which drug I would want!: https://t.co/I1mjKe6Y99

Jun 2, 2025 · 5,713 followers View post →
呼吸器内科医ACO
@respiratory0703 · X

未治療の肺サルコイドーシスに対するPSLとMTXの比較。 ベースラインから24週時までの%FVCは非劣性。 ただMTXは週15mgから開始、4週ごとに5mgずつ増量し最大投与量は週25mgというなかなかの高容量。日本人はもっと少なくともいいし、日本人データは欲しいところ https://t.co/UILHm0REOA

May 31, 2025 · 4 likes · 240 followers View post →
Leslie Vargas-Ramírez
@lilo1278 · X

RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…

May 28, 2025 · 52 shares · 2,449 followers View post →
STITCHES Medicine - the Best of Medical Research
@medicine.stitches.today · Bluesky

Methotrexate proved as effective as prednisone for treating pulmonary sarcoidosis, with potentially fewer side effects. by Kahlmann V, Janssen Bonás M (...) Wijsenbeek MS et 20 al. in N Engl J Med #MedSky

May 27, 2025 · 7 likes · 3 shares View post →
STITCHES Medicine - the Best of Medical Research
@STITCHESMed · X

Methotrexate proved as effective as prednisone for treating pulmonary sarcoidosis, with potentially fewer side effects. by Kahlmann V, Janssen Bonás M (...) Wijsenbeek MS et 20 al. in N Engl J Med https://t.co/GRo8AmghFs #MedX #MedResearch

May 27, 2025 · 83 followers View post →
旅人 tabito
@tabibito250 · X

First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate | New England Journal of Medicine https://t.co/rchfyZMTNc

May 24, 2025 · 1,075 followers View post →
Seyed Nahidi, MD
@Dr_Nahidi · X

Should methotrexate replace prednisone as first-line treatment for pulmonary sarcoidosis? Let the debate begin. Full Article: https://t.co/JIrzZIcQ8H

May 24, 2025 · 823 followers View post →
Almansour
@malmansour81 · X

RT @JesusLoarce: References: ▶️ https://t.co/ujff3sOfZb ▶️ https://t.co/USfUaBJyQO ▶️ https://t.co/LCxecJjpfk

May 23, 2025 · 1 share · 208 followers View post →
有機砂糖
@organic__sugar · X

肺サルコイドーシスの一次治療 ステロイドと比較してMTXでの治療が非劣性 (24wまでしかみていないので副作用の評価は要注意) https://t.co/t2AhWnQ34f

May 23, 2025 · 62 followers View post →
Ana Rigueira
@air-garcia.bsky.social · Bluesky

EvidenceAlerts | First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate. www.evidencealerts.com/Social/Artic...

May 23, 2025 View post →
Jesús Loarce
@JesusLoarce · X

References: ▶️ https://t.co/ujff3sOfZb ▶️ https://t.co/USfUaBJyQO ▶️ https://t.co/LCxecJjpfk

May 22, 2025 · 1 like · 1 share · 870 followers View post →
ガースー@関節系内科医
@gasu2019koto · X

治療適応のある肺サルコイドーシスに対するMTXをPSLと比較した非劣勢試験。24週時点での%FVC変化で非劣勢達成。 PSLは40mgから4w毎に10mgまで減量、MTXは15mg/wから最大25mgまで増量。有害事象はそれぞれの既知のやつが出てる感じ。 Patient-Reported Outcomeも2群で同程度。 https://t.co/cjzstdnGMD

May 22, 2025 · 13 likes · 2,025 followers View post →
Sovetorax Tips
@tipssovetorax · X

Tratamiento de primera línea de sarcoidosis pulmonar, prednisona o metotrexato 1 DOI: 10.1056/NEJMoa2501443

May 21, 2025 · 1 like · 3,247 followers View post →
Dr. Nazifa Kadery, PharmD, RPh
@dose_of_naz · X

#PREDMETH: 1L Treatment of #PulmonarySarcoidosis with #Prednisone or #Methotrexate #NEJM #ATS2025 https://t.co/hphkuMHIvK

May 21, 2025 · 1 like · 257 followers View post →
Kriti Kishor MD,DM
@kriti_lhmc · X

RT @autoinMI_tauli: NEJM: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate ⏩MTX noninferior to prednisone for…

May 21, 2025 · 23 shares · 357 followers View post →
María Jesús Montesa
@montesa_maria · X

¿Por fin una alternativa a la prednisona como 1ª línea en la #sarcoidosis pulmonar?

May 21, 2025 · 3 likes · 1 share · 1,982 followers View post →
DaniReuma
@dani_reuma · X

RT @autoinMI_tauli: NEJM: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate ⏩MTX noninferior to prednisone for…

May 21, 2025 · 23 shares · 361 followers View post →
Yuni G
@yunigap · X

RT @autoinMI_tauli: NEJM: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate ⏩MTX noninferior to prednisone for…

May 20, 2025 · 23 shares · 57 followers View post →
Fahad Alawfi
@fahadmemo · X

RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…

May 20, 2025 · 52 shares · 199 followers View post →
ong beng hooi
@ongbenghooi1 · X

RT @autoinMI_tauli: NEJM: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate ⏩MTX noninferior to prednisone for…

May 20, 2025 · 23 shares · 534 followers View post →
Pawan Rao MD, FASN
@nephronus · X

RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…

May 20, 2025 · 52 shares · 995 followers View post →
azfarali
@azfaralilungtxp · X

RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…

May 20, 2025 · 52 shares · 159 followers View post →
Adeel Nasrullah, MD
@adeel_nasrullah · X

RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…

May 20, 2025 · 52 shares · 847 followers View post →
J.un
@j2290un · X

RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…

May 20, 2025 · 52 shares · 88 followers View post →
Jose Campos
@JoseCamposMD · X

RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…

May 20, 2025 · 52 shares · 4,966 followers View post →
Carlos Ávila
@CarlosAR016 · X

RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…

May 20, 2025 · 52 shares · 276 followers View post →
cadranel jacques
@CadranelJ · X

RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…

May 20, 2025 · 52 shares · 1,593 followers View post →
Felipe MR
@Reumirez · X

RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…

May 20, 2025 · 52 shares · 202 followers View post →
Daniela Orozco Acosta
@DanielaOR · X

RT @autoinMI_tauli: NEJM: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate ⏩MTX noninferior to prednisone for…

May 20, 2025 · 23 shares · 319 followers View post →
Bharat Balan, MD, MS
@bharatbalan · X

RT @KaminskiMed: Wow! Just in time for #ATS2025 - First Sarcoidosis RCT @NEJM this century is out - Methotrexate is equal to Prednisone…

May 20, 2025 · 6 shares · 819 followers View post →
AngryPhDstudent❗️❗️❗️
@ONNESHA092 · X

RT @autoinMI_tauli: NEJM: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate ⏩MTX noninferior to prednisone for…

May 20, 2025 · 23 shares · 182 followers View post →
Carlos Andrés Celis-Preciado
@pulmonology101 · X

RT @autoinMI_tauli: NEJM: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate ⏩MTX noninferior to prednisone for…

May 20, 2025 · 23 shares · 4,345 followers View post →
loladelpuerto
@loladlpuerto · X

RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…

May 20, 2025 · 52 shares · 140 followers View post →
Emmanuel Edwar Siddig
@emmanue34897812 · X

RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…

May 20, 2025 · 52 shares · 308 followers View post →
HS
@HaythamSharar · X

RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…

May 20, 2025 · 52 shares · 122 followers View post →
Adnan Khan
@Adnan_KhanMD · X

RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…

May 20, 2025 · 52 shares · 510 followers View post →
Adnan Khan
@Adnan_KhanMD · X

RT @KaminskiMed: Wow! Just in time for #ATS2025 - First Sarcoidosis RCT @NEJM this century is out - Methotrexate is equal to Prednisone…

May 20, 2025 · 6 shares · 510 followers View post →
Dr.Salim.rheumatologist
@FtrSalim · X

RT @autoinMI_tauli: NEJM: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate ⏩MTX noninferior to prednisone for…

May 20, 2025 · 23 shares · 105 followers View post →
Fred
@TonyChristieisG · X

RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…

May 20, 2025 · 52 shares · 166 followers View post →
Ali ihsan OLUK
@KasosMete · X

RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…

May 20, 2025 · 52 shares · 555 followers View post →
Jesús Loarce
@JesusLoarce · X

RT @autoinMI_tauli: NEJM: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate ⏩MTX noninferior to prednisone for…

May 20, 2025 · 23 shares · 870 followers View post →
@UMASMutuaTerrassa
@UMAS_Mutua · X

RT @autoinMI_tauli: NEJM: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate ⏩MTX noninferior to prednisone for…

May 20, 2025 · 23 shares · 494 followers View post →
Muhammad Adrish, MD, MBA
@AdrishMD · X

RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…

May 20, 2025 · 52 shares · 625 followers View post →
José Mª Gª Quintana
@jose_g_quintana · X

RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…

May 20, 2025 · 52 shares · 846 followers View post →
Prashant chotalia
@Drpvc · X

RT @autoinMI_tauli: NEJM: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate ⏩MTX noninferior to prednisone for…

May 20, 2025 · 23 shares · 481 followers View post →
PunchaleeK
@PunchaleeK · X

RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…

May 19, 2025 · 52 shares · 190 followers View post →
Darlynton with a Y
@MeatIsMeaty · X

RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…

May 19, 2025 · 52 shares · 633 followers View post →
உன்னைப்போல் ஒருவன்
@vinopan007 · X

RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…

May 19, 2025 · 52 shares · 229 followers View post →
Andres Palacios Sarabia
@AndresPasa14 · X

RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…

May 19, 2025 · 52 shares · 107 followers View post →
ちろ剤師★薬物療法ニキ
@Toki_nd2525 · X

RT @nebetake: 肺サルコイドーシスへのステロイド vs MTXのRCT Primary endpointのFVC改善においてMTXはステロイドに非劣性。副作用の内容は薬剤ごとに異なる。 心サルコイドーシスでもステロイドが1stですが、MTXが使われることもあるので気…

May 19, 2025 · 3 shares · 5,754 followers View post →
Hiroyuki Sato 佐藤宏行
@foreverhero0819 · X

RT @nebetake: 肺サルコイドーシスへのステロイド vs MTXのRCT Primary endpointのFVC改善においてMTXはステロイドに非劣性。副作用の内容は薬剤ごとに異なる。 心サルコイドーシスでもステロイドが1stですが、MTXが使われることもあるので気…

May 19, 2025 · 3 shares · 3,782 followers View post →
Asif Hasan Khan
@asifdmcasif · X

RT @autoinMI_tauli: NEJM: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate ⏩MTX noninferior to prednisone for…

May 19, 2025 · 23 shares · 436 followers View post →
Tetsuma Kawaji, MD, PhD. FJCC/川治徹真
@tetsumaK1 · X

RT @nebetake: 肺サルコイドーシスへのステロイド vs MTXのRCT Primary endpointのFVC改善においてMTXはステロイドに非劣性。副作用の内容は薬剤ごとに異なる。 心サルコイドーシスでもステロイドが1stですが、MTXが使われることもあるので気…

May 19, 2025 · 3 shares · 771 followers View post →
Takeru Nabeta
@nebetake · X

肺サルコイドーシスへのステロイド vs MTXのRCT Primary endpointのFVC改善においてMTXはステロイドに非劣性。副作用の内容は薬剤ごとに異なる。 心サルコイドーシスでもステロイドが1stですが、MTXが使われることもあるので気になるところです https://t.co/W6Khcl0ISH

May 19, 2025 · 15 likes · 3 shares · 2,179 followers View post →
plcariou
@LouisCariou · X

RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…

May 19, 2025 · 52 shares · 60 followers View post →
Benjamin Thoreau
@ThoreauBenjamin · X

RT @HadjadjJerome: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate https://t.co/uX7ywaIFi8

May 19, 2025 · 2 shares · 614 followers View post →
Deven Patel
@DevenPatelMD · X

RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…

May 19, 2025 · 52 shares · 980 followers View post →
Irakli Tskhakaia
@iraklizumab · X

RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…

May 19, 2025 · 52 shares · 43 followers View post →
Almansour
@malmansour81 · X

RT @autoinMI_tauli: NEJM: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate ⏩MTX noninferior to prednisone for…

May 19, 2025 · 23 shares · 208 followers View post →
Caesar De Melniboné
@CesarDMelnibone · X

RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…

May 19, 2025 · 52 shares · 123 followers View post →
Elad Sharon
@EladSharonMD · X

RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…

May 19, 2025 · 52 shares · 3,838 followers View post →
Reena Singh
@EndoReena · X

RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…

May 19, 2025 · 52 shares · 33 followers View post →
Zubair Khalid
@DrZKhalid · X

RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…

May 19, 2025 · 52 shares · 215 followers View post →
Fabio Varon MD. MsC. PhD.
@FABIOVARON · X

RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…

May 19, 2025 · 52 shares · 3,052 followers View post →
Jaume Bordas Martinez
@jbordasmartinez · X

RT @autoinMI_tauli: NEJM: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate ⏩MTX noninferior to prednisone for…

May 19, 2025 · 23 shares · 286 followers View post →
Otavio Ranzani
@otavio_ranzani · X

RT @KaminskiMed: Wow! Just in time for #ATS2025 - First Sarcoidosis RCT @NEJM this century is out - Methotrexate is equal to Prednisone…

May 19, 2025 · 6 shares · 34,668 followers View post →
Michele Emdin
@MicheleEmdin · X

RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…

May 19, 2025 · 52 shares · 1,014 followers View post →
William
@Milligw · X

RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…

May 19, 2025 · 52 shares · 252 followers View post →
Ivonne Lourdes Mamani
@Ivonne_Lou · X

RT @autoinMI_tauli: NEJM: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate ⏩MTX noninferior to prednisone for…

May 19, 2025 · 23 shares · 320 followers View post →
José Mª Gª Quintana
@jose_g_quintana · X

RT @autoinMI_tauli: NEJM: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate ⏩MTX noninferior to prednisone for…

May 19, 2025 · 23 shares · 846 followers View post →
Najia X.
@najaxth · X

RT @autoinMI_tauli: NEJM: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate ⏩MTX noninferior to prednisone for…

May 19, 2025 · 23 shares · 170 followers View post →
Najia X.
@najaxth · X

RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…

May 19, 2025 · 52 shares · 170 followers View post →
Etienne Rivière
@EtienneRivire1 · X

RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…

May 19, 2025 · 52 shares · 195 followers View post →
Wei-Guo Ma, MD
@Dr_Ma_of_PUMC · X

RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…

May 19, 2025 · 52 shares · 2,369 followers View post →
alexis angibaud
@AlexisAngibaud · X

RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…

May 19, 2025 · 52 shares · 18 followers View post →
Iftikharnadeem
@Iftikharnadeem8 · X

RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…

May 19, 2025 · 52 shares · 57 followers View post →
Samuel Akaakole Mensah
@akaakole_mensah · X

RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…

May 19, 2025 · 52 shares · 351 followers View post →
Hatim Raffaa
@HatimRaffaa · X

RT @autoinMI_tauli: NEJM: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate ⏩MTX noninferior to prednisone for…

May 19, 2025 · 23 shares · 20 followers View post →
Nouf Al hemmadi
@NoufAhmedAlham2 · X

RT @autoinMI_tauli: NEJM: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate ⏩MTX noninferior to prednisone for…

May 19, 2025 · 23 shares · 1,274 followers View post →
Niyi
@NiyiMk · X

RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…

May 19, 2025 · 52 shares · 1,844 followers View post →
Amy S
@AmyS_MD · X

RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…

May 19, 2025 · 52 shares · 347 followers View post →
Raj Sreedhar, MD
@RajSreedhar3 · X

RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…

May 19, 2025 · 52 shares · 132 followers View post →
Walid Alkeridy وليد الكريدي
@WalidAlkeridy · X

First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate | New England Journal of Medicine https://t.co/foYWldIwpu

May 19, 2025 · 1 like · 1,287 followers View post →
Edward Robinson
@edwardlabs · X

RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…

May 19, 2025 · 52 shares · 26 followers View post →
Melina Ivone Tejada Ruiz
@TejadaIvone · X

RT @autoinMI_tauli: NEJM: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate ⏩MTX noninferior to prednisone for…

May 19, 2025 · 23 shares · 55 followers View post →
Linternista
@Linternistas · X

RT @NEJM: Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1…

May 19, 2025 · 52 shares · 248 followers View post →
NEJM
@NEJM · X

Original Article: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate (PREDMETH trial) https://t.co/1K1FSMQERF Editorial: Methotrexate as Initial Therapy for Symptomatic Pulmonary Sarcoidosis? https://t.co/SD8ix5qLqe #ATS2025 | @atscommunity https://t.co/isWQE7yn1y

May 19, 2025 · 141 likes · 52 shares · 935,642 followers View post →
Autoinmunes Medicina Interna Parc Taulí
@autoinMI_tauli · X

NEJM: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate ⏩MTX noninferior to prednisone for 1st-line treatment ⏩Similar lung function outcomes week 24. ⏩fewer side effects. ⏩ Could guide treatment choice (selected patients) https://t.co/pRebB1G1LM https://t.co/PuqL84i8HA

May 19, 2025 · 59 likes · 23 shares · 1,120 followers View post →
Thomas Moulinet
@MoulinetThomas · X

RT @HadjadjJerome: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate https://t.co/uX7ywaIFi8

May 19, 2025 · 2 shares · 72 followers View post →
Jerome HADJADJ
@HadjadjJerome · X

First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate https://t.co/uX7ywaIFi8

May 18, 2025 · 6 likes · 2 shares · 825 followers View post →
旅人 tabito
@tabibito250 · X

First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate | New England Journal of Medicine https://t.co/rchfyZNrCK

May 18, 2025 · 1 like · 1,075 followers View post →
Iván Darío Bravo Tobar. M.D. | M.Sc. | Ph.D.
@idbravotobar.bsky.social · Bluesky

First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate | New England Journal of Medicine www.nejm.org/doi/full/10....

May 18, 2025 View post →
Romatolog
@Nurullah_Akkoc · X

First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate : Initial treatment with MTX was noninferior to that with prednisone with regard to the change from baseline to week 24 in the percentage of the predicted FVC https://t.co/6mb62QxEae

May 18, 2025 · 1 like · 1,493 followers View post →
NEJM.org
@nejm.org · Bluesky

In the PREDMETH trial, first-line treatment of pulmonary sarcoidosis with methotrexate was noninferior to that with prednisone regarding the change at 24 weeks in the percentage of the predicted forced vital capacity. Full trial results: nej.md/4kdaf0o #ATS2025 @atscommunity.bsky.social

May 18, 2025 · 20 likes · 7 shares View post →