An ancient regulatory variant of ACSF3 influences the coevolution of increased human height and basal metabolic rate via metabolic homeostasis https://t.co/hoJ7FWqJFT
An ancient regulatory variant of ACSF3 influences the coevolution of increased human height and basal metabolic rate via metabolic homeostasis.
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May 2025 – Aug 2025Where it's discussed
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News16 articles
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X / Twitter9 posts
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Bluesky4 posts
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YouTube2 videos
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The discussions revolve around personal and ancestral connections to the research, exemplified by statements like 'I'm Natufian, I'm 1.90m' and comparisons to historical populations like Yamnayas. The tone is casual and reflective, with some participants emphasizing personal relevance and others briefly mentioning the scientific focus, indicating moderate interest and engagement without deep analysis or critique.
Most discussions show curiosity but not explicit agreement or disagreement with the findings, with some individuals expressing personal relevance or skepticism.
Participants demonstrate moderate interest, as they reference the study and relate it to personal ancestry or traits, but there is limited deep discussion.
Comments include personal anecdotes, references to other populations, or brief mentions of the study's implications, indicating some level of active engagement.
The discussions suggest that the publication influences thoughts on human evolution and genetics, but they do not highlight widespread or profound societal impact.
Abstract in brief
- Anatomically modern humans have higher basal metabolic rates and greater height than non-human apes, which this study examines for genetic underpinnings.
- A specific regulatory mutation, rs34590044-A, is linked to increased height and metabolic rates by enhancing the expression of the ACSF3 gene.
- This mutation has undergone positive selection in the British population over the last 20,000 years, particularly in the last 5,000 years, indicating its association with adaptation to a meat-rich diet.
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Most liked on X and BlueskyAn ancient regulatory variant of ACSF3 influences the coevolution of increased human height and basal metabolic rate via metabolic homeostasis https://t.co/R7nNzXpTlX
An ancient regulatory variant of ACSF3 influences the coevolution of increased human height and basal metabolic rate via metabolic homeostasis https://t.co/5WZtOVdzYz
An ancient regulatory variant of ACSF3 influences the coevolution of increased human height and basal metabolic rate via metabolic homeostasis www.cell.com/cell-genomic...
An ancient regulatory variant of ACSF3 influences the coevolution of increased human height and basal metabolic rate via metabolic homeostasis: Cell Genomics www.cell.com/cell-genomic...
An ancient regulatory variant of ACSF3 influences the coevolution of increased human height and basal metabolic rate via metabolic homeostasis: Cell Genomics https://t.co/xJf9bbjBEU
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Genetic Mutation Influencing Human Height and Metabolism
A mutation in mitochondrial machinery, identified as rs34590044A, has contributed to human height and metabolic traits by enhancing ACSF3 gene activity, which aids amino acid breakdown and prevents toxic buildup. This…
@damasiousc @PJudiciaria An ancient regulatory variant of ACSF3 influences the coevolution of increased human height and basal metabolic rate via metabolic homeostasis. I’m Natufian, I’m 1,90m, with the same lineages of Einstein, wouldn’t trade them for increased height/BMI from Yamnayas (dark triads). https://t.co/ncvQpYi4a5 https://t.co/KzfplaeVMu
An ancient regulatory variant of ACSF3 influences the coevolution of increased human height and basal metabolic rate via metabolic homeostasis: Cell Genomics https://t.co/LaeG9Yrg9i
An ancient regulatory variant of ACSF3 influences the coevolution of increased human height and basal metabolic rate via metabolic homeostasis https://t.co/R7nNzXpTlX
An ancient regulatory variant of ACSF3 influences the coevolution of increased human height and basal metabolic rate via metabolic homeostasis: Cell Genomics https://t.co/xJf9bbjBEU
An ancient regulatory variant of ACSF3 influences the coevolution of increased human height and basal metabolic rate via metabolic homeostasis: Cell Genomics www.cell.com/cell-genomic...
An ancient regulatory variant of ACSF3 influences the coevolution of increased human height and basal metabolic rate via metabolic homeostasis: Cell Genomics www.cell.com/cell-genomic...
RT @CellGenomics: An ancient regulatory variant of ACSF3 influences the coevolution of increased human height and basal metabolic rate via…
An ancient regulatory variant of ACSF3 influences the coevolution of increased human height and basal metabolic rate via metabolic homeostasis www.cell.com/cell-genomic...
An ancient regulatory variant of ACSF3 influences the coevolution of increased human height and basal metabolic rate via metabolic homeostasis: Cell Genomics www.cell.com/cell-genomic...
RT @nrken19: An ancient regulatory variant of ACSF3 influences the coevolution of increased human height and basal metabolic rate via metab…
An ancient regulatory variant of ACSF3 influences the coevolution of increased human height and basal metabolic rate via metabolic homeostasis https://t.co/hoJ7FWqJFT
RT @CellGenomics: An ancient regulatory variant of ACSF3 influences the coevolution of increased human height and basal metabolic rate via…
An ancient regulatory variant of ACSF3 influences the coevolution of increased human height and basal metabolic rate via metabolic homeostasis https://t.co/5WZtOVdzYz