BMC Cancer May 2025 PMID 40448255

The role of Adiponectin and Leptin in Colorectal Cancer and Adenoma: a systematic review and meta-analysis.

Iman Elahi Vahed, Mahsa Moshgelgosha, Abdolmajid Kor, Mona Minadi, Faezeh Ebrahimi, Aylar Azhdarian, Mobina Arjmandi, Aida Alamdar, Maede Zare, Niloufar Shabani, Hossein Soltaninejad, Mohammad Rahmanian

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Mentions

Peak: 3 in May 2025

across 2 sources since May 2025

Extended reach

141,657

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2,406

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May 2025 – Jun 2025

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AI synopsis

What people are saying

Discussions emphasize the potential of adiponectin and leptin to influence colorectal health, with phrases like

AgreementModerate agreement

Most discussions reflect a consensus that the research highlights important aspects of hormones like adiponectin and leptin in colorectal health, showing some support for the study's implications.

InterestModerate interest

The social discussions demonstrate interest in the biological mechanisms and potential health impacts, with some users referencing recent scientific findings.

EngagementModerate engagement

Participants actively interpret the study's significance, question its broader applications, and relate it to health topics, indicating moderate engagement.

ImpactModerate impact

The conversations suggest these findings could influence public awareness and future research directions, reflecting a moderate level of impact.

Abstract in brief

This systematic review and meta-analysis examined how adiponectin and leptin, hormones related to fat tissue, influence the risk of colorectal cancer and adenoma, finding that higher adiponectin levels may decrease CRC risk while leptin may increase the risk of adenoma.
The study analyzed data from 30 articles and found that increased adiponectin was associated with a protective effect against CRC, especially in men, whereas leptin showed no significant link to CRC but was related to higher adenoma risk.
Overall, the results suggest that adiponectin might help prevent colorectal cancer, while leptin could contribute to its development; however, more research is needed to understand the exact biological mechanisms involved.

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All mentions

Adiponectin and Leptin's Impact on Colorectal Cancer Risk Analysis

This systematic review and meta-analysis examines how hormones related to fat tissue influence colorectal cancer and adenoma risk, highlighting adiponectin's protective role and leptin's potential contribution to risk.

中村直樹のロバストネス通信 · Jun 6, 2025 1,965 views

Hormonal Influence on Colorectal Cancer and Precursors

Colorectal cancer is a common yet potentially preventable disease. This video explains how adipokines like adiponectin and leptin, hormones from fat tissue, influence cancer risk. It highlights the importance of weight…

Robustness Newsletter · Jun 6, 2025 441 views

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