The discussions consistently show strong agreement and high engagement, with posts citing details such as increased oxidative stress, impaired blood vessel functions, and stroke risks induced by erythritol. The tone and choice of words like 'adversely affects', 'risk', and 'warnings' underscore the perceived importance and potential health impact of the study's findings.
AgreementStrong agreement
Most discussions express strong agreement with the study's findings, highlighting potential health risks of erythritol.
InterestHigh interest
Posts demonstrate high interest by discussing detailed mechanisms and raising concerns about consumer safety.
EngagementHigh engagement
Many users reference specific aspects of the research, sharing insights, raising questions, and emphasizing implications.
ImpactHigh impact
The collective tone suggests recognition of the study's significant potential to influence consumer choices and regulatory considerations.
Abstract in brief
Erythritol, a common nonnutritive sweetener, increases oxidative stress in brain endothelial cells by boosting reactive oxygen species (ROS) and antioxidant proteins, which may impair cell function.
It causes a decrease in nitric oxide (NO) production and an increase in endothelin-1 (ET1) levels, indicating that erythritol negatively affects blood vessel regulation in the brain.
Additionally, erythritol reduces tissue-type plasminogen activator (tPA) release, which is important for blood flow and clot breakdown, suggesting it could harm brain vascular health.
não vou entrar nos méritos e deficiências dos estudos em si—os dois foram realizados in vitro—mas para quem quiser ler, estão aqui:
sobre a sucralose-6-acetato: https://t.co/wIGfKmpQ6b
sobre o eritritol: https://t.co/GERO7xB2w7
#Erythritol exposure impairs key functions in brain blood vessel cells, increasing #OxidativeStress and reducing #NitricOxide signaling, which may elevate stroke risk. Further research is recommended. https://t.co/4DVDFWwFv6 https://t.co/P5SGLv6oOk
Jun 12, 2025 · 28 likes · 22 shares · 173,198 followersView post →
BH
Brady Holmer
@Brady_H · X
The non-nutritive sweetener erythritol adversely affects brain microvascular endothelial cell function | Journal of Applied Physiology | American Physiological Society https://t.co/EZGwCYZI1g
Oct 18, 2025 · 17 likes · 27,249 followersView post →
From artificial sweeteners like aspartame to natural options like stevia, this video explores the health effects and safety profiles of various sugar substitutes, including recent findings on erythritol's potential…
Erythritol and allulose are marketed as healthy natural sugar alternatives. This video examines scientific evidence on their metabolism, effects on blood sugar, heart health, and safety, based on the latest research and…
The non-nutritive sweetener erythritol adversely affects brain microvascular endothelial cell function | Journal of Applied Physiology | American Physiological Society https://t.co/EZGwCYZI1g
Oct 18, 2025 · 17 likes · 27,249 followersView post →
TH
Tupper HORNER
@THorner52683 · X
RT @VeeLarisova: SUGAR ALCOHOLS ARE BAD FOR THE BRAIN AND HEART!!!! We always knew it at Chief and now the science is finally emerging. Rea…
Oct 14, 2025 · 2 shares · 431 followersView post →
SUGAR ALCOHOLS ARE BAD FOR THE BRAIN AND HEART!!!! We always knew it at Chief and now the science is finally emerging. Read comments for the study conclusion
https://t.co/g3Ho2nO08J
Oct 3, 2025 · 3 likes · 2 shares · 4 followersView post →
Jeff Robinson, CEO and Chairman of $MRES and $RLAB
@contrariansmind · X
The non-nutritive sweetener erythritol adversely affects brain microvascular endothelial cell function | Journal of Applied Physiology | American Physiological Society https://t.co/2wIi7WnvRm
Aug 15, 2025 · 1 like · 3,744 followersView post →
JS
John Siracusa
@john_siracusa · X
RT @LoriShemek: https://t.co/EHvJmS4BSG
Aug 13, 2025 · 10 shares · 19,898 followersView post →
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John Siracusa
@john_siracusa · X
RT @LoriShemek: https://t.co/EHvJmS4BSG
Aug 3, 2025 · 10 shares · 19,898 followersView post →
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Japan LCD Promotion Association
@JLCDPA · X
The study found that erythritol increased oxidative stress and antioxidant protein expression, suggesting potential adverse effects on brain microvascular endothelial cell function.
https://t.co/moZAF0K16l
Κασσάνδροσ Full-time Future Forecaster until 2027.
@JeanMichelFleur · X
Berry, A. R. et al. (2025).
The non-nutritive sweetener erythritol adversely affects brain microvascular endothelial cell function.
Journal of Applied Physiology, 138(6), 1571–1577.
https://t.co/gXDP6MuG1B https://t.co/u1JleGLnOf
The study exposed brain cells in a petri dish to 6mM erythritol for 24 hours (not 3 hours as the abstract + news articles incorrectly state).At this concentration, they saw increased oxidative stress, reduced nitric oxide, and impaired clot-busting ability https://t.co/q1AoWofTK5
caused blood vessels to constrict, reduced the production of natural clot-busting compounds, and increased levels of cell-damaging free radicals."
Auburn R. Berry et al, “The non-nutritive sweetener erythritol adversely affects brain microvascular endothelial cell function”, JAP
Guys, take a look at these findings.
The non-nutritive sweetener erythritol adversely affects brain microvascular endothelial cell function | Journal of Applied Physiology | American Physiological Society https://t.co/eZoGlvMarO
não vou entrar nos méritos e deficiências dos estudos em si—os dois foram realizados in vitro—mas para quem quiser ler, estão aqui:
sobre a sucralose-6-acetato: https://t.co/wIGfKmpQ6b
sobre o eritritol: https://t.co/GERO7xB2w7
Recent study finds that the non-nutritive sweetener erythritol negatively impacts brain microvascular endothelial cell function, highlighting potential risks for brain health. More research needed! #Erythritol #BrainHealth #EndothelialCells
https://t.co/a1Dcw0d5fm
since i “enjoy” breaking down the ways corporations and capitalist interests casually destroy lives through social murder: we have been using a sweetener since 2001 that is now shown to cause strokes and heart attacks. i wonder if anyone will be fired or punished for killing the american public!
Erythritol, at levels found in standard diet drinks, impairs brain microvascular cells by increasing oxidative stress, reducing NO production, altering ET-1 expression, and decreasing t-PA release — all in vitro.
| American Physiological Society https://t.co/LzCCVyP0nD
Jul 21, 2025 · 1 like · 1,035 followersView post →
ES
Eduardo Suarez
@EduardoSuarez25 · X
The non-nutritive sweetener erythritol adversely affects brain microvascular endothelial cell function | Journal of Applied Physiology | American Physiological Society https://t.co/O68UWdNs9p
The non-nutritive sweetener erythritol adversely affects brain microvascular endothelial cell function | Journal of Applied Physiology | American Physiological Society https://t.co/VMyV3aHISr
Stevia/brain research needed. Meanwhile: IN VITRO "The non-nutritive sweetener erythritol adversely affects brain microvascular endothelial cell function." (Berry et al. 2025; open access)
https://t.co/BVkawoPwy3
The non-nutritive sweetener erythritol adversely affects brain microvascular endothelial cell function | Journal of Applied Physiology | American Physiological Society https://t.co/o6OiEy31BZ
Erythritol adversely affects oxidative stress, NO production, ET-1 production, and t-PA release in brain microvascular endothelial cells, potentially contributing to the increased risk of ischemic stroke associated with erythritol.
lmao
https://t.co/H3OJTZHOnw
The non-nutritive sweetener erythritol adversely affects brain microvascular endothelial cell function | Journal of Applied Physiology | American Physiological Society https://t.co/DoPTo5Lz4L
More red flags for artificial sweeteners, the latest being a lab study that showed adverse effect of erythritol on cells that line blood vessels. https://t.co/JNr13y8pfu
See link
@FooleryT @simonmaechling I literally read this yesterday saying it's lethal.
https://t.co/hzTAnjTRt4
But for me, the major health consequence is that all the sweeteners destroy your gut. Enjoy your crohns, ibs, and uc.
L'edulcorant eritritol podria augmentar el risc d'accidents cardiovasculars i cerebrovasculars. Això suggereixen en aquest estudi on han sotmès a dosis usuals (com la típica d'un refresc) d'eritritol a cèl·lules endotelials microvasculars del cervell. https://t.co/0UfHxh2fKZ
Short Report by AR Berry et al. (@CUBoulderIPHY) The non-nutritive sweetener #erythritol adversely affects #brain #microvascular #endothelialcellfunction
The non-nutritive sweetener erythritol adversely affects brain microvascular endothelial cell function | Journal of Applied Physiology | American Physiological Society @RobertKennedyJr @SecKennedy
POPULAR SUGAR SUBSTITUTE IMPAIRS CELL FUNCTIONS VITAL FOR BRAIN BLOOD VESSEL HEALTH – NEW STUDY
https://t.co/h3WHIW46Qf
75% INCREASED REACTIVE OXYGEN SPECIES PRODUCTION WHICH CAN DAMAGE CELLS AND WEAKEN THE #BLOOD–BRAIN BARRIER
30% DISRUPT CEREBRAL FLOW
https://t.co/cUC3gdkYuk https://t.co/YmJceuF6W3
3/In der Studie "The Non-Nutritive Sweetener Erythritol Adversely Affects Brain Microvascular Endothelial Cell Function", die im Journal of Applied Physiology veröffentlicht wurde, entwarfen Forscher In-vitro-Experimente, um die zellulären Folgen der Erythrit-Exposition auf die
Jun 13, 2025 · 1 like · 1 share · 3,415 followersView post →
NW
NP AGARWAL世界一フォローを目指しますAiming best in world.
@np_grwl · X
RT @medical_xpress: #Erythritol exposure impairs key functions in brain blood vessel cells, increasing #OxidativeStress and reducing #Nitri…
Jun 12, 2025 · 22 shares · 1,786 followersView post →
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serrgv
@serrgv · X
RT @medical_xpress: #Erythritol exposure impairs key functions in brain blood vessel cells, increasing #OxidativeStress and reducing #Nitri…
Jun 12, 2025 · 22 shares · 144 followersView post →
TM
Tomasz Mrowicki
@tomrowicki · X
RT @medical_xpress: #Erythritol exposure impairs key functions in brain blood vessel cells, increasing #OxidativeStress and reducing #Nitri…
Jun 12, 2025 · 22 shares · 1,037 followersView post →
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Booklover848
@LadyBookworm117 · X
RT @medical_xpress: #Erythritol exposure impairs key functions in brain blood vessel cells, increasing #OxidativeStress and reducing #Nitri…
Jun 12, 2025 · 22 shares · 576 followersView post →
FA
Fandomguy (Destructive Creation arc)
@sciencefandom · X
RT @medical_xpress: #Erythritol exposure impairs key functions in brain blood vessel cells, increasing #OxidativeStress and reducing #Nitri…
Jun 12, 2025 · 22 shares · 921 followersView post →
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Aerycrow
@Aerycrow · X
RT @medical_xpress: #Erythritol exposure impairs key functions in brain blood vessel cells, increasing #OxidativeStress and reducing #Nitri…
Jun 12, 2025 · 22 shares · 1,953 followersView post →
PM
PDHAD, MCAS, PTSD and ME
@FatigueMe92484 · X
RT @medical_xpress: #Erythritol exposure impairs key functions in brain blood vessel cells, increasing #OxidativeStress and reducing #Nitri…
Jun 12, 2025 · 22 shares · 1,218 followersView post →
PO
Phys.org
@physorg_com · X
RT @medical_xpress: #Erythritol exposure impairs key functions in brain blood vessel cells, increasing #OxidativeStress and reducing #Nitri…
Jun 12, 2025 · 22 shares · 1,016,860 followersView post →
MX
Medical Xpress
@medical_xpress · X
#Erythritol exposure impairs key functions in brain blood vessel cells, increasing #OxidativeStress and reducing #NitricOxide signaling, which may elevate stroke risk. Further research is recommended. https://t.co/4DVDFWwFv6 https://t.co/P5SGLv6oOk
Jun 12, 2025 · 28 likes · 22 shares · 173,198 followersView post →
DS
David Silverberg
@SilverbergDave · X
We should all be watching how much erythritol we include in our diet. I just found out in a new study from @CUBoulder how this low-calorie sweetener is associated with higher risk of stroke. https://t.co/gnEL2rhave
Jun 10, 2025 · 1 like · 2,988 followersView post →
... 10.1152/japplphysiol. 00276.2025](https://doi.org/10.1152/japplphysiol. 00276.2025) · May be an image of coconut and wooden spoon. John Lin and ...