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The discussions mainly praise the study for its promising results in alleviating kidney damage in Alport syndrome, with phrases like 'potential new therapy' and 'significant impact.' The tone reflects a mix of curiosity, optimism, and recognition of the study’s importance, with examples citing the role of chemical chaperones in protein folding and potential disease treatment.
Most discussions express strong support and positive validation of the study's findings, emphasizing its potential benefits.
The posts show moderate interest, highlighting the novelty and relevance of chemical chaperones for kidney disease but with limited depth.
Several contributions include mentions of related research, potential therapies, or technical aspects, indicating active engagement.
The discussions suggest that the findings are viewed as impactful, with mentions of future therapeutic implications and scientific advances.
New data from the Deltas lab on targeting ER stress in Alport Syndrome. Chemical chaperone 4-phenylbutyrate treatment alleviates the kidney phenotype in a mouse model of Alport syndrome with a pathogenic variant in Col4a3 https://t.co/31x9XTNelP https://t.co/4sTe5OzFe0
Chemical chaperone 4-phenylbutyrate treatment alleviates the kidney phenotype in a mouse model of Alport syndrome with a pathogenic variant in Col4a3 - Kidney International www.kidney-international.org/article/S008...
New data from the Deltas lab on targeting ER stress in Alport Syndrome. Chemical chaperone 4-phenylbutyrate treatment alleviates the kidney phenotype in a mouse model of Alport syndrome with a pathogenic variant in Col4a3 www.sciencedirect.com/science/arti...
Chemical chaperone 4-phenylbutyrate treatment alleviates the kidney phenotype in a mouse model of Alport syndrome with a pathogenic variant in Col4a3 @Kidney_Int #openaccess https://t.co/6qTHt5an1L
Chemical chaperone 4-phenylbutyrate treatment alleviates the kidney phenotype in a mouse model of Alport syndrome with a pathogenic variant in Col4a3 doi.org/10.1016/j.kint.2025.05.016 #MedSky #NephSky #OpenAccess #ckd #chronickidneydisease #alportsyndrome
Pavlos Ioannou, and Christoforos Odiatis, https://t.co/m8d3WLrWwq join the @UCYOfficial channel to discuss the new scientific findings inherited kidney disease—Alport syndrome. Watch here: https://t.co/Mxiqc725eq #biobankcy #H2020 #EU2020 #UCY #biobank #Cyprus
This study explores how chemical chaperones like 4-phenylbutyrate (4PBA) can improve kidney health in mouse models of Alport syndrome, caused by collagen IV mutations. Results suggest 4PBA potential as a therapy by…
Unfolding the potential—chemical chaperones in #Alportsyndrome doi.org/10.1016/j.kint.2025.07.006 Original article: doi.org/10.1016/j.kint.2025.05.016 #KICommentary #NephSky #MedSky #CKD
RT @biobank_cy: Pavlos Ioannou, and Christoforos Odiatis, https://t.co/m8d3WLrWwq join the @UCYOfficial channel to discuss the new scienti…
Pavlos Ioannou, and Christoforos Odiatis, https://t.co/m8d3WLrWwq join the @UCYOfficial channel to discuss the new scientific findings inherited kidney disease—Alport syndrome. Watch here: https://t.co/Mxiqc725eq #biobankcy #H2020 #EU2020 #UCY #biobank #Cyprus
Chemical chaperone 4-phenylbutyrate treatment alleviates the kidney phenotype in a mouse model of Alport syndrome with a pathogenic variant in Col4a3 - Kidney International www.kidney-international.org/article/S008...
Chemical chaperone 4-phenylbutyrate treatment alleviates the kidney phenotype in a mouse model of Alport syndrome with a pathogenic variant in Col4a3 https://t.co/CqCB7ibINP https://t.co/VBEItiyWIw
RT @ASPNeph: Chemical chaperone 4-phenylbutyrate treatment alleviates the kidney phenotype in a mouse model of Alport syndrome with a patho…
Chemical chaperone 4-phenylbutyrate treatment alleviates the kidney phenotype in a mouse model of Alport syndrome with a pathogenic variant in Col4a3 #openaccess buff.ly/9HxjWAq
Chemical chaperone 4-phenylbutyrate treatment alleviates the kidney phenotype in a mouse model of Alport syndrome with a pathogenic variant in Col4a3 @Kidney_Int #openaccess https://t.co/6qTHt5an1L
RT @TomVanAgtmael: New data from the Deltas lab on targeting ER stress in Alport Syndrome. Chemical chaperone 4-phenylbutyrate treatment a…
New data from the Deltas lab on targeting ER stress in Alport Syndrome. Chemical chaperone 4-phenylbutyrate treatment alleviates the kidney phenotype in a mouse model of Alport syndrome with a pathogenic variant in Col4a3 www.sciencedirect.com/science/arti...
New data from the Deltas lab on targeting ER stress in Alport Syndrome. Chemical chaperone 4-phenylbutyrate treatment alleviates the kidney phenotype in a mouse model of Alport syndrome with a pathogenic variant in Col4a3 https://t.co/31x9XTNelP https://t.co/4sTe5OzFe0
Chemical chaperone 4-phenylbutyrate treatment alleviates the kidney phenotype in a mouse model of Alport syndrome with a pathogenic variant in Col4a3 doi.org/10.1016/j.kint.2025.05.016 #MedSky #NephSky #OpenAccess #ckd #chronickidneydisease #alportsyndrome